- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Isernia to Rome
Showing times and prices for Aug 05
Cheapest price
$17
Average price
$25
Fastest journey
2 h 25 m
Average duration
2 h 27 m
Buses per day
10
Distance
149 km
Cheap tickets
The best way to find a cheap bus ticket from Isernia to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Isernia to Rome will cost around $25 if you buy it on the day, but the cheapest tickets can be found for only $17.
Fast buses
Of the 10 buses that leave Isernia for Rome on Wed, Aug 05, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Aug 05 the direct buses cover the 149 km distance in an average of 2 h 27 m but if you time it right, some buses will get you there in just 2 h 25 m .
On Wed, Aug 05 the slowest buses will take 2 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
treno 23359 effettuato con bus CB7135:45 PM2h30Isernia station8:15 PMRome Termini$171One-way0 transfers- treno 23351 effettuato con bus CB7072:40 PM2h30Isernia station5:10 PMRome Termini$171One-way0 transfers
- treno 23341 effettuato con bus CB7016:25 AM2h35Isernia station9:00 AMRome Termini$171One-way0 transfers
- treno 23349 effettuato con bus CB7051:15 PM2h30Isernia station3:45 PMRome Tiburtina$171One-way0 transfers
- treno 23361 effettuato con bus CB7158:10 PM2h25Isernia station10:35 PMRome Termini$171One-way0 transfers
0598:25 AM2h25Isernia, Piazza della Repubblica (F. Martino bus station)10:50 AMRoma, Autostazione Tiburtina$221One-way0 transfers- treno 23361 effettuato con bus CB7158:10 PM2h25Isernia station10:35 PMRome Termini$171One-way0 transfers
FlixBus11:35 AM2h25Isernia, Piazza della Repubblica (F. Martino bus station)2:00 PMRoma, Autostazione Tiburtina$171One-way0 transfers- treno 23359 effettuato con bus CB7135:45 PM2h30Isernia station8:15 PMRome Termini$171One-way0 transfers
- treno 23351 effettuato con bus CB7072:40 PM2h30Isernia station5:10 PMRome Termini$171One-way0 transfers
Journey information
Overview: Bus from Isernia to Rome
ItalyItaly
Buses from Isernia to Rome run on average 10 times per day, taking around 2h 22m. Cheap bus tickets for this journey start at $10 if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:15, the last at 23:56. The fastest bus covers the 92 miles (149 km) distance in 2h 10m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 92 miles (149 km) |
Average bus duration 2h 22m |
Cheapest ticket price $10 |
Buses per day 10 |
Direct buses 6 |
Fastest bus 2h 10m |
First bus 12:15 AM |
Last bus 11:56 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Mon |
Best time to book 35 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Isernia to Rome Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar | Departure Time 06:10AM | Arrival Time 07:40AM | Duration 1h30 | Departure days Tue | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 06:20AM | Arrival Time 08:10AM | Duration 1h50 | Departure days Tue | Cheapest price $14 |
Operator Regionale | Departure Time 06:25AM | Arrival Time 09:00AM | Duration 2h35 | Departure days Everyday | Cheapest price $17 |
Operator Frecciarossa | Departure Time 06:50AM | Arrival Time 10:13AM | Duration 3h23 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $36 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 09:30AM | Duration 1h30 | Departure days Mon | Cheapest price $12 |
Operator Regionale | Departure Time 08:20AM | Arrival Time 10:55AM | Duration 2h35 | Departure days Everyday | Cheapest price $17 |
Operator Marino Autolinee | Departure Time 08:25AM | Arrival Time 10:50AM | Duration 2h25 | Departure days Everyday | Cheapest price $6 |
Operator BlaBlaCar | Departure Time 09:10AM | Arrival Time 10:30AM | Duration 1h20 | Departure days Wed | Cheapest price $13 |
Operator BlaBlaCar | Departure Time 09:50AM | Arrival Time 11:10AM | Duration 1h20 | Departure days Fri, Sat | Cheapest price $15 |
Operator BlaBlaCar | Departure Time 10:00AM | Arrival Time 11:20AM | Duration 1h20 | Departure days Thu | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 10:30AM | Arrival Time 11:50AM | Duration 1h20 | Departure days Thu | Cheapest price $13 |
Operator BlaBlaCar | Departure Time 10:40AM | Arrival Time 12:00PM | Duration 1h20 | Departure days Mon | Cheapest price $11 |
Operator BlaBlaCar | Departure Time 11:00AM | Arrival Time 12:20PM | Duration 1h20 | Departure days Mon, Wed | Cheapest price $9 |
Operator BlaBlaCar | Departure Time 11:10AM | Arrival Time 12:30PM | Duration 1h20 | Departure days Sat | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 11:30AM | Arrival Time 12:50PM | Duration 1h20 | Departure days Tue, Sun | Cheapest price $12 |
Operator FlixBus | Departure Time 11:35AM | Arrival Time 02:00PM | Duration 2h25 | Departure days Everyday | Cheapest price $16 |
Operator BlaBlaCar | Departure Time 12:20PM | Arrival Time 02:00PM | Duration 1h40 | Departure days Wed | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 12:30PM | Arrival Time 02:00PM | Duration 1h30 | Departure days Sat | Cheapest price $15 |
Operator BlaBlaCar | Departure Time 12:40PM | Arrival Time 02:00PM | Duration 1h20 | Departure days Thu | Cheapest price $13 |
Operator Regionale | Departure Time 01:15PM | Arrival Time 03:45PM | Duration 2h30 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $17 |
Operator BlaBlaCar | Departure Time 01:20PM | Arrival Time 02:50PM | Duration 1h30 | Departure days Wed, Fri | Cheapest price $12 |
Operator Frecciargento | Departure Time 01:50PM | Arrival Time 05:05PM | Duration 3h15 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $55 |
Operator BlaBlaCar | Departure Time 02:00PM | Arrival Time 03:20PM | Duration 1h20 | Departure days Wed | Cheapest price $13 |
Operator Regionale | Departure Time 02:40PM | Arrival Time 05:10PM | Duration 2h30 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $17 |
Operator BlaBlaCar | Departure Time 02:50PM | Arrival Time 04:10PM | Duration 1h20 | Departure days Sun | Cheapest price $10 |
Operator Regionale | Departure Time 03:00PM | Arrival Time 05:30PM | Duration 2h30 | Departure days Sun | Cheapest price $17 |
Operator BlaBlaCar | Departure Time 03:10PM | Arrival Time 04:30PM | Duration 1h20 | Departure days Mon | Cheapest price $9 |
Operator BlaBlaCar | Departure Time 03:20PM | Arrival Time 04:40PM | Duration 1h20 | Departure days Sat | Cheapest price $14 |
Operator BlaBlaCar | Departure Time 03:50PM | Arrival Time 05:30PM | Duration 1h40 | Departure days Thu, Sat, Sun | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 04:50PM | Arrival Time 06:20PM | Duration 1h30 | Departure days Tue | Cheapest price $14 |
Operator Regionale | Departure Time 05:05PM | Arrival Time 07:35PM | Duration 2h30 | Departure days Sun | Cheapest price $17 |
Operator BlaBlaCar | Departure Time 05:40PM | Arrival Time 07:30PM | Duration 1h50 | Departure days Thu | Cheapest price $8 |
Operator Regionale | Departure Time 05:45PM | Arrival Time 08:15PM | Duration 2h30 | Departure days Mon, Tue, Wed, Thu, Fri, Sat | Cheapest price $17 |
Operator Regionale | Departure Time 08:10PM | Arrival Time 10:35PM | Duration 2h25 | Departure days Everyday | Cheapest price $17 |
Operator BlaBlaCar | Departure Time 08:40PM | Arrival Time 10:00PM | Duration 1h20 | Departure days Sun | Cheapest price $13 |
Operator BlaBlaCar | Departure Time 08:50PM | Arrival Time 10:10PM | Duration 1h20 | Departure days Tue | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 11:40PM | Arrival Time 01:00AM | Duration 1h20 | Departure days Mon | Cheapest price $11 |
Live departures
Isernia to Rome bus times
The table below shows live departures for Isernia to Rome buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| treno 23341 effettuato con bus CB701 | 6:25 AM Isernia station | 2h35 | 9:00 AM Rome Termini | 0 transfersDirect | |
treno 5181 effettuato con bus CB905+ FRECCIAROSSA 8348 | 6:50 AM Isernia station | 3h23 | 10:13 AM Rome Termini | 1 transfer | |
| treno 23347 effettuato con bus CB703 | 8:20 AM Isernia station | 2h35 | 10:55 AM Rome Termini | 0 transfersDirect | |
| 059 | 8:25 AM Isernia, Piazza della Repubblica (F. Martino bus station) | 2h25 | 10:50 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
| FlixBus | 11:35 AM Isernia, Piazza della Repubblica (F. Martino bus station) | 2h25 | 2:00 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
| treno 23349 effettuato con bus CB705 | 1:15 PM Isernia station | 2h30 | 3:45 PM Rome Tiburtina | 0 transfersDirect | |
treno 5189 effettuato con bus CB907+ FRECCIARGENTO 8314 | 1:50 PM Isernia station | 3h15 | 5:05 PM Rome Termini | 1 transfer | |
| treno 23351 effettuato con bus CB707 | 2:40 PM Isernia station | 2h30 | 5:10 PM Rome Termini | 0 transfersDirect | |
| treno 23359 effettuato con bus CB713 | 5:45 PM Isernia station | 2h30 | 8:15 PM Rome Termini | 0 transfersDirect | |
| treno 23361 effettuato con bus CB715 | 8:10 PM Isernia station | 2h25 | 10:35 PM Rome Termini | 0 transfersDirect | |
Find all the dates and times for this journey
Why should you book Isernia to Rome buses with Omio?
FlixBus as well as ATM Azienda di Trasporti Molisana S.p.A. offer buses services from Isernia to Rome.
Omio is an official ticket reseller for all your travel options from Isernia to Rome.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of ATM Azienda di Trasporti Molisana S.p.A. to find the best option for your trip from Isernia to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Isernia to Rome.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Isernia to Rome.
Bus providers: FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A. from Isernia to RomeYou can travel by bus between Isernia to Rome with FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A. for as low as $10. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
2h 10m
Cheapest Price
$10
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
BlaBlaCar
About
BlaBlaCar is a French online marketplace for carpooling, connecting drivers with empty seats and passengers traveling to the same destination to share costs. Founded in 2006, it operates in Europe and Latin America, boasting 26 million active members. The platform also includes BlaBlaCar Bus, an intercity bus service. BlaBlaCar's name comes from its rating system for drivers' chattiness: "Bla" for quiet, "BlaBla" for talkative, and "BlaBlaBla" for very chatty. The company aims to be the leading marketplace for shared travel, offering affordable and sustainable solutions by combining carpooling with bus journeys.
Luggage & cancellation policy
BlaBlaCar frequency
5 a day
ATM Azienda di Trasporti Molisana S.p.A.
Luggage & cancellation policy
Average Duration
2h 10m
Cheapest Price
$12
ATM Azienda di Trasporti Molisana S.p.A. frequency
3 a day
Complete guide to Rome
Things to do in Rome
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
- Must visit
Capitoline Museums
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
- Must visit
Galleria Borghese
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
- Must visit
Piazza Navona
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
- Must visit
Piazza di Spagna
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
- Must visit
Trastevere
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Pasta Alla Carbonara
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Pasta All'Amatriciana
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta Alla Gricia
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Il Ristorante - Niko Romito
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Felice A Testaccio
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Pizzarium
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Euro (€)
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Average meal costs
- Budget
- €8-12 for pizza, panini, or street food.
- Mid-range
- €20-35 per person for a restaurant meal.
- Fine dining
- €60+ per person for upscale dining.
- Coffee
- €1.20-3 for espresso or cappuccino.
Tipping culture
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
TicketAppy ATAC Roma
Get the appOfficial public transport app
Prices
- Single ticket
- €1.50
- Day pass
- €7.00
To the city center
Via Marsala, Rome -> Piazza Barberini, Rome
- Distance
- 1.6 km
- Travel time
- 12 min
- Tap a contactless card or device on ATAC metro gates and on validators aboard buses and trams to buy a BIT ticket.
- Validate paper tickets before boarding or at metro gates. A Roma 24H pass costs €7.00 if you need multiple rides in one day.
FAQs: Bus from Isernia to Rome
Find answers to the most common questions about traveling from Isernia to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Isernia to Rome can start from as little as $10 when you book in advance. The average bus ticket price for Isernia to Rome is $18 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Isernia to Rome is 2h 10m to travel the 92 miles (149 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Isernia to Rome leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Isernia to Rome leaves at 11:56 PM.
Yes, there are 6 direct buses a day from Isernia to Rome with FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A.. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Isernia to Rome, you can count on FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A. for the best way to get you to Rome. You can also check all possible bus companies who offer a service between Isernia and Rome and compare the amenities they offer before buying a bus ticket.
It's helpful to compare your options as there are 2 ways to travel between Isernia and Rome including taking a train and bus.
Yes, there are bathrooms on board the bus from Isernia to Rome for bus company FlixBus.
Yes, the following accessibility options are available when taking the bus from Isernia to Rome:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Whether you can cancel your bus ticket from Isernia to Rome depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Isernia to Rome.
Yes, the following luggage options are included when booking a bus ticket from Isernia to Rome:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Isernia to Rome:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Isernia to Rome. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Isernia to Rome with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Isernia to Rome with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Isernia to Rome with the following bus company: FlixBus.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Rome, travelers should be cautious of pickpocketing, especially in crowded areas like public transport, major landmarks, and popular squares. Common scams include unofficial taxi drivers overcharging and street vendors selling counterfeit goods. It's advisable to use authorized taxis, keep valuables secure, and be wary of distraction techniques used by scammers in busy tourist spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Isernia to Rome
Most Isernia to Rome buses use the Isernia, Piazza della Repubblica (Autostazione F. Martino) to Roma, Autostazione Tiburtina station pair. Use this guide to compare Isernia and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Isernia
Arrival bus stations in Rome
Isernia, Piazza della Repubblica (Autostazione F. Martino)
Roma, Autostazione Tiburtina
City-centre transport
Getting to Roma, Autostazione Tiburtina from Rome city centre
Bus490, 495 · 16m · $2 · every ~22 min
SubwayMeb · 7m · $2 · every ~15 min
Most popular bus connections from Isernia
More options for your journey from Isernia to Rome
Here are some other resources that might have the information you need
Most popular buses to and from Rome and Isernia
Most popular bus connections to Rome
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
