The cheapest and fastest buses from Isernia to Rome
Cheapest price
$13
Average price
$23
Fastest journey
1 h 30 m
Average duration
1 h 40 m
Buses per day
7
Distance
149 km
The best way to find a cheap bus ticket from Isernia to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Isernia to Rome will cost around $23 if you buy it on the day, but the cheapest tickets can be found for only $13.
Of the 7 buses that leave Isernia for Rome on Thu, Nov 06, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Nov 06 the direct buses cover the 149 km distance in an average of 1 h 40 m but if you time it right, some buses will get you there in just 1 h 30 m .
On Thu, Nov 06 the slowest buses will take 2 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare train and bus for Isernia to Rome
Omio recommends booking the train as it is the most popular option from Isernia to Rome among Omio's users. If you are prioritising price take the bus with prices starting from €10. For those with little time consider booking a bus which can get you there in 2h 25m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.0 - 0.1kg. The ticket price range depends on the travel mode: a bus costs an average of €10, and a train costs an average of €14.
Distance: 92 miles (149 km)
Compare bus with
| Bus | Most popular Train |
|---|---|
€19 Average price Cheapest | €24 Average price |
2h 55m Average total duration Fastest 2h 25m Onboard + 30m Additional time* | 3h 17m Average total duration 2h 47m Onboard + 30m Additional time* |
0.1 - 0.4kg CO2 emissions | 0.0 - 0.1kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Isernia to Rome Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator BlaBlaCar | Departure Time 04:10AM | Arrival Time 05:30AM | Duration 1h20 | Departure days Sat | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 06:00AM | Arrival Time 07:30AM | Duration 1h30 | Departure days Wed | Cheapest price $12 |
Operator BlaBlaCar | Departure Time 08:30AM | Arrival Time 10:40AM | Duration 2h10 | Departure days Wed | Cheapest price $14 |
Operator BlaBlaCar | Departure Time 10:30AM | Arrival Time 12:00PM | Duration 1h30 | Departure days Thu | Cheapest price $16 |
Operator BlaBlaCar | Departure Time 10:50AM | Arrival Time 01:20PM | Duration 2h30 | Departure days Wed | Cheapest price $12 |
Operator FlixBus | Departure Time 11:25AM | Arrival Time 08:30PM | Duration 9h05 | Departure days Thu, Fri, Sat | Cheapest price $43 |
Operator Regionale | Departure Time 01:30PM | Arrival Time 04:00PM | Duration 2h30 | Departure days Sat | Cheapest price $18 |
Operator BlaBlaCar | Departure Time 03:00PM | Arrival Time 04:50PM | Duration 1h50 | Departure days Wed | Cheapest price $17 |
Operator BlaBlaCar | Departure Time 03:10PM | Arrival Time 04:40PM | Duration 1h30 | Departure days Thu | Cheapest price $13 |
Operator FlixBus | Departure Time 03:50PM | Arrival Time 10:45PM | Duration 6h55 | Departure days Wed, Thu, Fri, Sat | Cheapest price $25 |
Operator BlaBlaCar | Departure Time 04:10PM | Arrival Time 05:50PM | Duration 1h40 | Departure days Thu | Cheapest price $19 |
Operator BlaBlaCar | Departure Time 04:40PM | Arrival Time 06:00PM | Duration 1h20 | Departure days Sat | Cheapest price $18 |
Operator BlaBlaCar | Departure Time 05:20PM | Arrival Time 07:00PM | Duration 1h40 | Departure days Wed | Cheapest price $15 |
Operator BlaBlaCar | Departure Time 07:50PM | Arrival Time 10:00PM | Duration 2h10 | Departure days Thu | Cheapest price $23 |
Operator BlaBlaCar | Departure Time 08:20PM | Arrival Time 09:50PM | Duration 1h30 | Departure days Thu | Cheapest price $16 |
Live departures
Isernia to Rome bus times
The table below shows live departures for Isernia to Rome buses for today, Wednesday, November 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 2:50 PM Isernia, Piazza della Repubblica (F. Martino bus station) | 6h55 | 9:45 PM Roma, Autostazione Tiburtina | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Isernia to Rome by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 06
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Nov 14
Nov 15
Nov 16
Nov 17
Nov 18
Nov 19
Journey information
Overview: Bus from Isernia to Rome
Distance 92 miles (149 km) |
Average bus duration 2h 25m |
Cheapest ticket price $12 (€10) |
Buses per day 8 |
Direct buses 6 |
Fastest bus 2h 25m |
First bus 00:15 |
Last bus 23:58 |
Bus providers: FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A. from Isernia to RomeYou can travel by bus between Isernia to Rome with FlixBus, BlaBlaCar, ATM Azienda di Trasporti Molisana S.p.A. for as low as $12 (€10). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
ATM Azienda di Trasporti Molisana S.p.A.
FAQs: Bus from Isernia to Rome

Passengers board the bus most frequently from Isernia, Piazza della Repubblica (F. Martino bus station), which is located around 0.7 miles (1.1 km) away from the city centre, and they get off the bus at Roma, Autostazione Tiburtina, located 3.5 miles (5.6 km) away from the city centre.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Colosseum, an ancient amphitheater known for its gladiatorial contests and iconic architecture
- Vatican Museums, a vast collection of art and historical artifacts including the Sistine Chapel
- Roman Forum, the ruins of ancient Rome's center for public life and government
- Pantheon, a well-preserved Roman temple with a striking dome and oculus
- Trevi Fountain, a famous Baroque fountain where visitors traditionally toss coins for good luck.
- Explore Trastevere, a charming neighborhood with narrow streets and vibrant nightlife
- Take a stroll through Villa Borghese, a beautiful park with museums and gardens
- Enjoy a gelato at Piazza Navona, a lively square with fountains and street artists
- Visit the Spanish Steps, a popular spot for people-watching and enjoying the view
- Discover the Catacombs, ancient underground burial sites with guided tours.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Isernia to Rome, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Isernia to Rome
Most popular bus connections from Isernia
More options for your journey from Isernia to Rome
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