- Must visit
Museo Nazionale del Paleolitico di Isernia
Major Paleolithic museum beside the renowned prehistoric site. Essential for understanding early human settlement in Europe.
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The cheapest and fastest trains from Rome to Isernia
Showing times, prices and bookable tickets for Nov 04
- Cheapest price on Nov 04
- $17
- Average ticket price on Nov 04
- $17
- Fastest journey on Nov 04
- 2 h 5 m
- Average journey duration on Nov 04
- 2 h 19 m
- Trains on Nov 04
- 3
- Distance
- 149 km
Cheap tickets
The best way to find a cheap train ticket from Rome to Isernia is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Isernia will cost around $17 if you buy it on the day, but the cheapest tickets can be found for only $17.
Fast trains
On Wed, Nov 04, we found 3 trains from Rome to Isernia, including 3 direct services.
On Wed, Nov 04 the direct trains cover the 149 km distance in an average of 2 h 19 m but if you time it right, some trains will get you there in just 2 h 5 m .
On Wed, Nov 04 the slowest trains will take 2 h 48 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1:35 PM 2h05 Rome 3:40 PM Isernia $17 1 One-way 0 transfers5:07 PM 2h48 Rome 7:55 PM Isernia $17 1 One-way 0 transfers12:35 PM 2h05 Rome 2:40 PM Isernia $17 1 One-way 0 transfers
1:35 PM 2h05 Rome 3:40 PM Isernia $17 1 One-way 0 transfers12:35 PM 2h05 Rome 2:40 PM Isernia $17 1 One-way 0 transfers5:07 PM 2h48 Rome 7:55 PM Isernia $17 1 One-way 0 transfers
Journey information
Overview: Train from Rome to Isernia
ItalyItaly
Trains from Rome to Isernia run on average 11 times per day, taking around 2h 47m. Cheap train tickets for this journey start at $17 but you can travel from only $6 by bus.
There are 5 trains per day. The earliest train runs at 04:50, the last at 23:56. The fastest train covers the 92 miles (149 km) distance in 1h 59m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $6
Distance 92 miles (149 km) |
Average train duration 2h 47m |
Cheapest ticket price $17 |
Trains per day 11 |
Direct trains 5 |
Fastest train 1h 59m |
First train 4:50 AM |
Last train 11:56 PM |
Cheapest Month Jan |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Fri |
Best time to book 14 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $6
Frequently asked questions about your Rome to Isernia trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Rome to Isernia.
Train ticket prices from Rome to Isernia can vary. The cheapest ticket starts at $17, while the average price is around $33.
The train from Rome to Isernia takes 1h 59m and runs 11 per day.
The first train from Rome to Isernia leaves at 4:50 AM.
The distance by train from Rome to Isernia is 92 miles (149 km).
The last train from Rome to Isernia leaves at 11:56 PM.
Yes, there is a direct train from Rome to Isernia. This service operates 5 times per day, provided by Regionale.
Live departures
Rome to Isernia train times
The table below shows live departures for Rome to Isernia trains for today, Tuesday, November 3. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 FRECCIAROSSA 9643+Regionale 23495 | 6:53 PM Rome Termini | 2h50 | 9:43 PM Isernia station | 1 transfer | |
| Regionale 23381 | 8:07 PM Rome Termini | 2h19 | 10:26 PM Isernia station | 0 transfersDirect | |
| Wednesday, November 4 | |||||
| 12:35 PM Rome | 2h05 | 2:40 PM Isernia | 0 transfersDirect | |
| 1:35 PM Rome | 2h05 | 3:40 PM Isernia | 0 transfersDirect | |
| 5:07 PM Rome | 2h48 | 7:55 PM Isernia | 0 transfersDirect | |
Find all the dates and times for this journey
Why should you book Rome to Isernia trains with Omio?
Regionale as well as Intercity, Intercity Notte, Frecciarossa and more offer trains services from Rome to Isernia.
Omio is the only official third party seller for Regionale tickets.
Why book with Omio vs Regionale?
- Compare with other providers: On Omio, you can not only buy tickets for Regionale, but also compare tickets for the likes of Intercity, Intercity Notte or Frecciarossa to find the best option for your trip from Rome to Isernia.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Regionale with all available travel options, which are train and bus to ensure you get the best deal for traveling from Rome to Isernia.
Train companies: Regionale, Intercity, Intercity Notte, Frecciarossa from Rome to Isernia trainsRegionale, Intercity, Intercity Notte, Frecciarossa trains will get you between Rome and Isernia from $6. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Regionale
About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Regionale Duration
2h 5m
Cheapest Regionale Price
$17
Regionale frequency
10 a day
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone
Intercity
About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Intercity Duration
3h 13m
Cheapest Intercity Price
$28
Intercity frequency
1 a day
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone
Intercity Notte
About
Intercity Notte is an Italian train service operated by Trenitalia. It runs overnight services between major cities in Italy, making it a great option for travelers looking to save time and money. The Intercity Notte offers two types of trains: the Frecciarossa Notte and the Frecciargento Notte. The Frecciarossa Notte is the fastest train, with speeds of up to 300 km/h, while the Frecciargento Notte is slightly slower but still offers a comfortable journey. Both trains offer a range of onboard facilities, including comfortable seating, air conditioning, and Wi-Fi. Trenitalia offers a range of ticket types, including Standard, Comfort, and Business. Standard tickets are the most affordable, while Comfort and Business tickets offer additional benefits such as priority boarding and access to the lounge. The most popular routes for Intercity Notte are Rome to Milan, Rome to Venice, and Milan to Venice. These routes offer travelers the chance to explore some of Italy's most iconic cities in a convenient and comfortable way.
Luggage & cancellation policy
Average Intercity Notte Duration
3h 42m
Cheapest Intercity Notte Price
$28
Intercity Notte frequency
1 a day
Luggage included
1 handbag and 1 suitcase included in ticket price
Luggage storage
Luggage racks above seats and at carriage ends
Cancellation Policy
Cancellation possible according to ticket type conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full dining service and bar
Seat reservation
Seat reservation included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for disabled passengers
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs free.
Quiet zone
Frecciarossa
About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Frecciarossa Duration
1h 59m
Cheapest Frecciarossa Price
$20
Frecciarossa frequency
1 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone
Companies, tickets, and onboard amenities between Rome and Isernia
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Yes, there is a high-speed train from Rome to Isernia.
Yes, there is a night train from Rome to Isernia.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
Yes, rail passes such as the Eurail Italy Pass and Interrail Italy Pass are valid on most trains operated by Trenitalia and Italo within Italy, including regional, intercity, and high-speed trains, though some restrictions and seat reservation fees may apply.
Complete guide to Isernia
Things to do in Isernia
Discover the best of Isernia — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Isernia trip today.
- Recommended
Museo Archeologico di Santa Maria delle Monache
Archaeological area museum presenting finds from the ancient settlement. A strong companion visit to the cathedral and Roman remains.
- Recommended
Complesso Monumentale di Santa Maria delle Monache
Exhibition venue in a historic setting, often used for local heritage displays. Good for visitors interested in community-focused culture.
- Must visit
Corso Marcelli
Main historic street lined with palaces, churches, and shops. The best walk for absorbing Isernia's old-town atmosphere.
- Must visit
Centro Storico di Isernia
The historic center preserves medieval lanes, arches, and layered architecture. Ideal for slow exploration and local street photography.
- Recommended
Piazza Celestino V
Central square near the cathedral and Fontana Fraterna. A practical starting point for discovering the city's key monuments.
Lasagne Alla Molisana
Fresh pasta sheets layered with rich pork ragù, mozzarella, and caciocavallo. A Sunday and feast-day classic in Molise with deep family tradition.
Cavatelli
Small handmade cavatelli pasta, often served with tomato sauce, pork, or seasonal vegetables. It is one of Molise’s best-known home-style staples.
- Vegetarian
- Vegan
Pampanella E Minestra Di Erbe
Rustic soup of field greens, potatoes, beans, and cornbread or stale bread. A traditional peasant dish from the Isernia area, especially in colder months.
Ristorante Da Lulù
Established restaurant known for Molisan cooking, handmade pasta, and local meats in a refined but welcoming setting.
Osteria Le Antiche Mura
Well-regarded traditional venue serving regional specialties, grilled meats, and classic local dishes in a rustic atmosphere.
Ristorante Pizzeria La Strada
Casual, popular spot for pizza and southern Italian dishes, suited to an easy meal with locals and families.
Euro (€)
Moderate for Italy. Hotels and dining are usually cheaper than Rome or Florence, while local buses and coffee remain low-cost for most travelers.
Average meal costs
- Budget
- €8-12 for fast food or a simple meal.
- Mid-range
- €20-35 per person for a restaurant meal.
- Fine dining
- €50+ per person for upscale dining.
- Coffee
- €1.20-2.50 for espresso or cappuccino.
Tipping culture
Tipping is modest. Service may be included. Round up or leave 5-10% at restaurants for good service; round up taxi fares; small change is enough at cafes.
MooneyGo
Get the appOfficial public transport app
Prices
- Single ticket
- €1.20
- Day pass
- None
To the city center
Isernia Railway Station -> Piazza Andrea d'Isernia
- Distance
- 1 km
- Travel time
- 15 min
- Buy bus tickets before boarding; onboard sales may not be available on local services.
- Contactless bank card payment on board is not reliably available; carry a valid paper or mobile ticket.
Plan your visit to Isernia
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Isernia.
The Rome to Isernia train journey offers scenic views of the Italian countryside, including rolling hills and picturesque villages, providing a pleasant travel experience.
Popular day trips by train from Isernia include Naples, Venafro, Caserta, Cassino, Bojano.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Isernia, travelers should be cautious of petty theft, especially in crowded areas and near transportation hubs. It is advisable to stay vigilant with personal belongings and avoid accepting unsolicited offers from strangers. There are no widespread reports of specific scams targeting visitors, but standard travel precautions apply, such as using official taxi services and verifying ticket purchases to ensure safety and avoid fraud.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Trains from Rome to Isernia
Find answers to the most common questions about traveling from Rome to Isernia by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Isernia, this guide helps you travel smarter and with confidence.
Yes, you can take the train from Rome to Isernia.
popular train stations
Popular train stations from Rome to Isernia
Most Rome to Isernia trains use the Roma Termini to Isernia station pair. Use this guide to compare Rome and Isernia train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Departure train stations in Rome
Arrival train stations in Isernia
Which Rome station do trains to Isernia leave from?
Trains from Rome to Isernia leave from Roma Termini. The station is 1 miles (2 km) from Rome city centre at Piazza dei Cinquecento 1, 00185 Rome, Italy.
Roma TerminiPiazza dei Cinquecento 1, 00185 Rome, Italy+39 064745421
City-centre transport
Getting to Roma Termini from Rome city centre
Roma Termini is 1 km from Rome city centre. Public transport options include:
Metro linesA (red), B (blue)
Bus lines5, H, 38, 40 Express, 50 Express, 64, 66, 70, 75, 82, 90 Express, 92, 105, 150F, 223, 310, 590, 714, 910, C2, C3
Tram lines5, 14
Train linesItalo, FR, FA, FB, IC, ICN, EN, CNL, R, Leonardo Express
Roma Termini train station facilities and services
Roma Termini has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Car Rental, and Information Desk.
Food and drink
Food options include: Acafe, Moka Café, Roadhouse Grill, McDonald's, Gusto, Chef Express, Coop Minimarket, Mercato Centrale
Wi-Fi and ATMs
Free WiFi in the station. ATMs are there are ATMs in various locations around the station.
Tickets and information
The ticket office is open Mon - Sun: 06:30 - 22:00. Information desks are located near Platform 24.
Luggage and lost property
Luggage storage is provided by KiPoint and located on Platform 24. Open every day from 06:00 to 23:00.
Parking, taxis and toilets
Available at Roma Termini: Parking, Taxis, WC.
Bike and car services
Available at Roma Termini: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Roma Termini: The Sala Blu, Trenitalia's office of assistance for disabled travelers, is located next to Platform 1.
Shops, hotels and contact
Nearby hotels include Archi di Roma Guest House, Gemma di Roma, The Liberty Boutique Hotel.
Roma TiburtinaPiazzale Stazione Tiburtina, 00162 Roma RM, Italy+39 892021
City-centre transport
Getting to Roma Tiburtina from Rome city centre
Roma Tiburtina is 4 km from Rome city centre. Public transport options include:
Train8914, 9970, 9948, 9946, 9924, 9916, 9912, 9904, 8928, 8924, 8918, 8922, 8908, 8906, 8904, 8900, 8134, 9944, 9966, 9920, 9908, 8916, 8910, 9954, 9940 · 5m · $2 · every ~6 min
Bus490, 495 · 24m · $3 · every ~22 min
SubwayMeb · 13m · $3 · every ~15 min
Roma Tiburtina train station facilities and services
Roma Tiburtina has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Car Rental, and Information Desk.
Food and drink
Food options include: Rock n’ Coffee Roma, Arabian Kebab, Ingredienti, McDonald’s, Numb's Bakery Café
Wi-Fi and ATMs
Free, limited Wi-Fi available in the station for 15 minutes. ATMs are located on the ground floor level.
Tickets and information
The ticket office is open Mon - Sun: 06:35 - 20:20. Information desks are located inside the main terminal. .
Luggage and lost property
Luggage storage is luggage lockers are located in the station lobby.
Parking, taxis and toilets
Available at Roma Tiburtina: Parking, Taxis, WC.
Bike and car services
Available at Roma Tiburtina: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Roma Tiburtina: Accessible facilities include elevators and escalators.
Shops, hotels and contact
Nearby hotels include B&B Rome Tiburtina, B&B Alba Domus Roma, Hotel delle Province.
Roma TrasteverePiazza Flavio Biondo, 00153 Rome, Italy+39 06 575 5310
City-centre transport
Getting to Roma Trastevere from Rome city centre
Roma Trastevere is 2 km from Rome city centre. Public transport options include:
TrainRe, 4134, 4136, 4138, 4140, 4130, 34488, 34482, 34480, 34476, 34474, 4132, 4128 · 20m · $2 · every ~4 min
Bus170 · 36m · $3 · every ~10 min
170 · 39m · $3 · every ~10 min
Tram3 · 38m · $3 · every ~3 min
Roma Trastevere train station facilities and services
Roma Trastevere has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Information Desk, and Luggage Carts.
Food and drink
Food options include: Trattoria Da Enzo al 29, Osteria der Belli
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Roma Trastevere. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Roma Trastevere. Lost and found is available at the station.
Parking, taxis and toilets
Available at Roma Trastevere: Parking, Taxis, WC.
Bike and car services
Available at Roma Trastevere: Bike Parking.
Accessibility
Accessibility facilities are available at Roma Trastevere: Elevators, ramps, restrooms.
Shops, hotels and contact
Nearby hotels include Hotel San Francesco, Hotel Ripa Roma, Hotel Santa Maria.
Which Isernia station do trains from Rome arrive at?
Trains from Rome to Isernia arrive at Isernia. Isernia is from Isernia city centre.
IserniaPiazza della Repubblica, 86170 Isernia IS, Italy+39 0865 4131
City-centre transport
Getting to Isernia from Isernia city centre
Bus31 · 1m · $4
Isernia train station facilities and services
Isernia has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Information Desk, and Luggage Carts.
Food and drink
Food options include: Pasta e Pizza, Ristorante da Adriano
Wi-Fi and ATMs
Free.
Tickets and information
Ticket office support is available at Isernia. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Isernia. Lost and found is available at the station.
Parking, taxis and toilets
Available at Isernia: Parking, Taxis, WC.
Bike and car services
Available at Isernia: Bike Parking.
Accessibility
Accessibility facilities are available at Isernia: Ramps.
Shops, hotels and contact
Nearby hotels include Grand Hotel Europa, Hotel Ristorante Sayonara, Hotel La Tequila.
Train stations for Rome to Isernia
Check train stations information for Rome and Isernia, including where trains depart and arrive on this route.
The train station in Rome that goes to Isernia is Roma Termini, which connects to Isernia.
More options for your journey from Rome to Isernia
Here are some other resources that might have the information you need
Most popular trains to and from Isernia and Rome
Most popular train connections to Isernia
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