- Must visit
Museo Nazionale del Paleolitico di Isernia
Major Paleolithic museum beside the renowned prehistoric site. Essential for understanding early human settlement in Europe.
Cheapest price
$17
Average price
$21
Fastest journey
2 h 29 m
Average duration
4 h 21 m
Buses per day
4
Distance
96 km
The best way to find a cheap bus ticket from Pescara to Isernia is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pescara to Isernia will cost around $21 if you buy it on the day, but the cheapest tickets can be found for only $17.
Of the 4 buses that leave Pescara for Isernia on Tue, Aug 25, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, Aug 25 the direct buses cover the 96 km distance in an average of 4 h 21 m but if you time it right, some buses will get you there in just 2 h 29 m .
On Tue, Aug 25 the slowest buses will take 6 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








Omio recommends booking the bus as it is the most popular option from Pescara to Isernia among Omio's users. If you are prioritising price take the bus with prices starting from $20. For those with little time consider booking a bus which can get you there in 2h 53m. The ticket price range depends on the travel mode: a bus costs an average of $20, and a train costs an average of $33.
Distance: 59 miles (96 km)
Most popular Bus | Train | Driving |
|---|---|---|
$25 Average price Cheapest | $33 Average price | $38 Average price (fuel + tolls) |
3h 23m Average total duration Fastest 2h 53m Onboard + 30m Additional time* | 7h 12m Average total duration 6h 42m Onboard + 30m Additional time* | 2h 0m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Pescara to Isernia:
A bus is $8 (€7) less than a train for this route with tickets for a train from Pescara to Isernia costing on average $33 (€27).
Other travel options to Isernia take longer:
Train takes on average 6h 42m.
Tickets start at around $25 (€20) compared to roughly $38 (€30) in fuel and tolls — a saving of about $13 (€10). The journey takes 2h 53m versus 2h 0m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by Satam, FlixBus, BlaBlaCar.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Intercity Notte | Departure Time 04:28AM | Arrival Time 08:50AM | Duration 4h22 | Departure days Thu, Sat, Sun | Cheapest price $29 |
Operator BlaBlaCar | Departure Time 08:30AM | Arrival Time 10:50AM | Duration 2h20 | Departure days Mon | Cheapest price $17 |
Operator Regionale | Departure Time 10:10AM | Arrival Time 04:20PM | Duration 6h10 | Departure days Tue, Wed | Cheapest price $22 |
Operator Regionale | Departure Time 11:10AM | Arrival Time 05:20PM | Duration 6h10 | Departure days Tue, Sun | Cheapest price $22 |
Operator Regionale | Departure Time 11:14AM | Arrival Time 05:35PM | Duration 6h21 | Departure days Sun | Cheapest price $22 |
Operator Regionale | Departure Time 11:17AM | Arrival Time 05:35PM | Duration 6h18 | Departure days Sun | Cheapest price $22 |
Operator Intercity | Departure Time 12:03PM | Arrival Time 05:35PM | Duration 5h32 | Departure days Sun | Cheapest price $29 |
Operator Regionale | Departure Time 12:10PM | Arrival Time 06:10PM | Duration 6h00 | Departure days Thu, Fri, Sat | Cheapest price $22 |
Operator Regionale | Departure Time 12:14PM | Arrival Time 06:10PM | Duration 5h56 | Departure days Thu, Fri, Sat | Cheapest price $22 |
Operator FlixBus | Departure Time 12:15PM | Arrival Time 02:49PM | Duration 2h34 | Departure days Tue, Wed | Cheapest price $19 |
Operator Regionale | Departure Time 12:17PM | Arrival Time 06:10PM | Duration 5h53 | Departure days Thu, Fri, Sat | Cheapest price $22 |
Operator Frecciarossa | Departure Time 12:47PM | Arrival Time 06:10PM | Duration 5h23 | Departure days Thu, Fri, Sat, Sun | Cheapest price $37 |
Operator FlixBus | Departure Time 01:35PM | Arrival Time 04:04PM | Duration 2h29 | Departure days Tue, Wed | Cheapest price $17 |
Operator Regionale | Departure Time 03:05PM | Arrival Time 08:40PM | Duration 5h35 | Departure days Sun | Cheapest price $22 |
Operator Regionale | Departure Time 03:09PM | Arrival Time 08:40PM | Duration 5h31 | Departure days Sun | Cheapest price $22 |
Operator Regionale | Departure Time 03:12PM | Arrival Time 08:40PM | Duration 5h28 | Departure days Sun | Cheapest price $22 |
Operator FlixBus | Departure Time 03:35PM | Arrival Time 06:04PM | Duration 2h29 | Departure days Thu, Fri, Sat, Sun | Cheapest price $27 |
Operator FlixBus | Departure Time 03:50PM | Arrival Time 06:14PM | Duration 2h24 | Departure days Mon | Cheapest price $33 |
Operator Intercity | Departure Time 04:01PM | Arrival Time 08:40PM | Duration 4h39 | Departure days Sun | Cheapest price $29 |
Operator Frecciarossa | Departure Time 04:50PM | Arrival Time 08:40PM | Duration 3h50 | Departure days Thu, Sat, Sun | Cheapest price $37 |
Operator BlaBlaCar | Departure Time 05:40PM | Arrival Time 08:00PM | Duration 2h20 | Departure days Mon | Cheapest price $23 |
The table below shows live departures for Pescara to Isernia buses for today, Monday, August 24. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 3:50 PM Pescara, Terminal Bus | 2h24 | 6:14 PM Isernia, Piazza della Repubblica (F. Martino bus station) | 0 transfersDirect | |
| Tuesday, August 25 | |||||
![]() | 10:10 AM Pescara | 6h10 | 4:20 PM Isernia | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Pescara to Isernia run on average 8 times per day, taking around 2h 51m. Cheap bus tickets for this journey start at $13 (€11) if you book in advance.
There are 4 buses per day. The earliest bus runs at 05:25, the last at 19:50. The fastest bus covers the 59 miles (96 km) distance in 2h 29m.
Distance 59 miles (96 km) |
Average bus duration 2h 51m |
Cheapest ticket price $13 (€11) |
Buses per day 8 |
Direct buses 4 |
Fastest bus 2h 29m |
First bus 5:25 AM |
Last bus 7:50 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Fri |
Best time to book 6 days |
Discover the best of Isernia — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Isernia trip today.
Major Paleolithic museum beside the renowned prehistoric site. Essential for understanding early human settlement in Europe.
Archaeological area museum presenting finds from the ancient settlement. A strong companion visit to the cathedral and Roman remains.
Exhibition venue in a historic setting, often used for local heritage displays. Good for visitors interested in community-focused culture.
Main historic street lined with palaces, churches, and shops. The best walk for absorbing Isernia's old-town atmosphere.
The historic center preserves medieval lanes, arches, and layered architecture. Ideal for slow exploration and local street photography.
Central square near the cathedral and Fontana Fraterna. A practical starting point for discovering the city's key monuments.
Fresh pasta sheets layered with rich pork ragù, mozzarella, and caciocavallo. A Sunday and feast-day classic in Molise with deep family tradition.
Small handmade cavatelli pasta, often served with tomato sauce, pork, or seasonal vegetables. It is one of Molise’s best-known home-style staples.
Rustic soup of field greens, potatoes, beans, and cornbread or stale bread. A traditional peasant dish from the Isernia area, especially in colder months.
Established restaurant known for Molisan cooking, handmade pasta, and local meats in a refined but welcoming setting.
Well-regarded traditional venue serving regional specialties, grilled meats, and classic local dishes in a rustic atmosphere.
Casual, popular spot for pizza and southern Italian dishes, suited to an easy meal with locals and families.
Moderate for Italy. Hotels and dining are usually cheaper than Rome or Florence, while local buses and coffee remain low-cost for most travelers.
Tipping is modest. Service may be included. Round up or leave 5-10% at restaurants for good service; round up taxi fares; small change is enough at cafes.
Find answers to the most common questions about traveling from Pescara to Isernia by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Isernia, this guide helps you travel smarter and with confidence.

Most Pescara to Isernia buses use the Pescara, Terminal Bus to Isernia, Piazza della Repubblica (Autostazione F. Martino) station pair. Use this guide to compare Pescara and Isernia bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Pescara, Terminal Bus is 1 km from Pescara city centre. Public transport options include:
Pescara, Terminal Bus has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Caffè Terminal (in the station), Trattoria del Mare (0.5 km), Osteria La Vongola (0.7 km).
Free Wi-Fi. ATMs are located inside the terminal for cash withdrawals.
Ticket office support is available at Pescara, Terminal Bus.
Available at Pescara, Terminal Bus: Parking, Taxis, WC.
Accessibility facilities are available at Pescara, Terminal Bus: Elevators, ramps.
Isernia, Piazza della Repubblica (Autostazione F. Martino) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Nearby cafés and fast food outlets.
Wi-Fi is available at Isernia, Piazza della Repubblica (Autostazione F. Martino). ATMs are aTM located near the entrance.
Ticket office support is available at Isernia, Piazza della Repubblica (Autostazione F. Martino).
Available at Isernia, Piazza della Repubblica (Autostazione F. Martino): Parking, Taxis, WC.
Accessibility facilities are available at Isernia, Piazza della Repubblica (Autostazione F. Martino): Wheelchair accessible facility.
Here are some other resources that might have the information you need