- Must visit
Museo Nazionale del Paleolitico di Isernia
Major Paleolithic museum beside the renowned prehistoric site. Essential for understanding early human settlement in Europe.
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The cheapest and fastest buses from Cassino to Isernia
Showing times, prices and bookable tickets for Nov 02
- Cheapest price on Nov 02
- €6
- Average ticket price on Nov 02
- €6
- Fastest journey on Nov 02
- 1 h
- Average journey duration on Nov 02
- 1 h 29 m
- Buses on Nov 02
- 2
- Distance
- 36 km
Cheap tickets
The best way to find a cheap bus ticket from Cassino to Isernia is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Cassino to Isernia will cost around €6 if you buy it on the day, but the cheapest tickets can be found for only €6.
Fast buses
On Mon, Nov 02, we found 2 buses from Cassino to Isernia, including 1 direct services.
On Mon, Nov 02 the direct buses cover the 36 km distance in an average of 1 h 29 m but if you time it right, some buses will get you there in just 1 h .
On Mon, Nov 02 the slowest buses will take 1 h 58 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
Regionale 5805 · Autobus CB1065:47 AM 1h58 Cassino station 7:45 AM Isernia station €6 1 One-way 1 transfer- Autobus RM114
7:55 PM 1h00 Cassino station 8:55 PM Isernia station €6 1 One-way 0 transfers
- Autobus RM114
7:55 PM 1h00 Cassino station 8:55 PM Isernia station €6 1 One-way 0 transfers - Regionale 5805 · Autobus CB106
5:47 AM 1h58 Cassino station 7:45 AM Isernia station €6 1 One-way 1 transfer
Journey information
Overview: Bus from Cassino to Isernia
ItalyItaly
Take a bus from Cassino to Isernia and enjoy the approximately 22 miles (36 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 04:50, the last at 22:00.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €6
Plan this route
Journey facts
- Distance22 miles (36 km)
- First bus4:50 AM
- Last bus10:00 PM
- Cheapest MonthJan
- Cheapest DaySat
- High SeasonOct - Dec
- Low SeasonJan - Mar
- Busiest DayTue
- Least Busy DaySun
- Best time to book7 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €6
Frequently asked questions about your Cassino to Isernia trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Cassino to Isernia.
The earliest bus from Cassino to Isernia leaves at 4:50 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Cassino to Isernia leaves at 10:00 PM.
Cassino to Isernia Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Regionale | Departure Time 03:50AM | Arrival Time 05:45AM | Duration 1h55 | Departure days Thu, Fri, Sat | Cheapest price €6 |
Operator Regionale | Departure Time 04:34AM | Arrival Time 06:45AM | Duration 2h11 | Departure days Wed, Thu, Fri | Cheapest price €6 |
Operator Regionale | Departure Time 04:50AM | Arrival Time 06:45AM | Duration 1h55 | Departure days Wed, Thu, Fri, Sat | Cheapest price €6 |
Operator Regionale | Departure Time 05:47AM | Arrival Time 07:45AM | Duration 1h58 | Departure days Mon, Tue | Cheapest price €6 |
Operator BlaBlaCar | Departure Time 11:20AM | Arrival Time 11:30AM | Duration 0h10 | Departure days Sun | Cheapest price €3 |
Operator Regionale | Departure Time 05:55PM | Arrival Time 06:55PM | Duration 1h00 | Departure days Wed, Fri | Cheapest price €6 |
Operator Regionale | Departure Time 06:55PM | Arrival Time 07:55PM | Duration 1h00 | Departure days Wed, Thu, Sat | Cheapest price €6 |
Operator Regionale | Departure Time 07:55PM | Arrival Time 08:55PM | Duration 1h00 | Departure days Mon, Tue | Cheapest price €6 |
Operator BlaBlaCar | Departure Time 11:00PM | Arrival Time 11:30PM | Duration 0h30 | Departure days Sun | Cheapest price €4 |
Live departures
Cassino to Isernia bus times
The table below shows live departures for Cassino to Isernia buses for today, Sunday, November 1. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
 | 11:20 AM Cassino | 0h10 | 11:30 AM Isernia | 0 transfersDirect | |
| 11:00 PM Cassino | 0h30 | 11:30 PM Isernia | 0 transfersDirect | |
| Monday, November 2 | |||||
| Regionale 5805 · Autobus CB106 | 5:47 AM Cassino station | 1h58 | 7:45 AM Isernia station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Complete guide to Isernia
Things to do in Isernia
Discover the best of Isernia — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Isernia trip today.
- Recommended
Museo Archeologico di Santa Maria delle Monache
Archaeological area museum presenting finds from the ancient settlement. A strong companion visit to the cathedral and Roman remains.
- Recommended
Complesso Monumentale di Santa Maria delle Monache
Exhibition venue in a historic setting, often used for local heritage displays. Good for visitors interested in community-focused culture.
- Must visit
Corso Marcelli
Main historic street lined with palaces, churches, and shops. The best walk for absorbing Isernia's old-town atmosphere.
- Must visit
Centro Storico di Isernia
The historic center preserves medieval lanes, arches, and layered architecture. Ideal for slow exploration and local street photography.
- Recommended
Piazza Celestino V
Central square near the cathedral and Fontana Fraterna. A practical starting point for discovering the city's key monuments.
Lasagne Alla Molisana
Fresh pasta sheets layered with rich pork ragù, mozzarella, and caciocavallo. A Sunday and feast-day classic in Molise with deep family tradition.
Cavatelli
Small handmade cavatelli pasta, often served with tomato sauce, pork, or seasonal vegetables. It is one of Molise’s best-known home-style staples.
- Vegetarian
- Vegan
Pampanella E Minestra Di Erbe
Rustic soup of field greens, potatoes, beans, and cornbread or stale bread. A traditional peasant dish from the Isernia area, especially in colder months.
Ristorante Da Lulù
Established restaurant known for Molisan cooking, handmade pasta, and local meats in a refined but welcoming setting.
Osteria Le Antiche Mura
Well-regarded traditional venue serving regional specialties, grilled meats, and classic local dishes in a rustic atmosphere.
Ristorante Pizzeria La Strada
Casual, popular spot for pizza and southern Italian dishes, suited to an easy meal with locals and families.
Euro (€)
Moderate for Italy. Hotels and dining are usually cheaper than Rome or Florence, while local buses and coffee remain low-cost for most travelers.
Average meal costs
- Budget
- €8-12 for fast food or a simple meal.
- Mid-range
- €20-35 per person for a restaurant meal.
- Fine dining
- €50+ per person for upscale dining.
- Coffee
- €1.20-2.50 for espresso or cappuccino.
Tipping culture
Tipping is modest. Service may be included. Round up or leave 5-10% at restaurants for good service; round up taxi fares; small change is enough at cafes.
Plan your visit to Isernia
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Isernia.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Isernia, travelers should be cautious of petty theft, especially in crowded areas and near transportation hubs. It is advisable to stay vigilant with personal belongings and avoid accepting unsolicited offers from strangers. There are no widespread reports of specific scams targeting visitors, but standard travel precautions apply, such as using official taxi services and verifying ticket purchases to ensure safety and avoid fraud.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from Cassino to Isernia
Find answers to the most common questions about traveling from Cassino to Isernia by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Isernia, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 2 ways to travel between Cassino and Isernia including taking a train and bus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Most popular bus connections from Cassino
Most popular buses to and from Isernia and Cassino
Most popular bus connections to Isernia
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