- Must visit
Saint Louis Art Museum
Major fine arts museum in Forest Park with collections spanning ancient to modern works. A top cultural stop known for strong European, American, and global holdings.
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The cheapest and fastest buses from Rochester, NY to St. Louis, MO
Showing times and prices for Jun 21
Cheapest price
$128
Average price
$135
Fastest journey
1 d 1 h 15 m
Average duration
1 d 1 h 15 m
Buses per day
2
Distance
1170 km
Cheap tickets
The best way to find a cheap bus ticket from Rochester, NY to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rochester, NY to St. Louis, MO will cost around $135 if you buy it on the day, but the cheapest tickets can be found for only $128.
Fast buses
Of the 2 buses that leave Rochester, NY for St. Louis, MO on Sun, Jun 21, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jun 21 the direct buses cover the 1170 km distance in an average of 1 d 1 h 15 m but if you time it right, some buses will get you there in just 1 d 1 h 15 m .
On Sun, Jun 21 the slowest buses will take 1 d 1 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
10:10 AM25h15Rochester, NY11:25 AMSt. Louis, MO$1281One-way0 transfers- 11:10 AM25h15Rochester, NY12:25 PMSt. Louis, MO$1431One-way0 transfers
- 11:10 AM25h15Rochester, NY12:25 PMSt. Louis, MO$1431One-way0 transfers
- 10:10 AM25h15Rochester, NY11:25 AMSt. Louis, MO$1281One-way0 transfers
Travel Information
Compare train, bus, and flight for Rochester, NY to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Rochester, NY to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $108. For those with little time consider booking a flight which can get you there in 4h 10m. The ticket price range depends on the travel mode: a bus costs an average of $108, and a flight costs an average of $183.
Distance: 727 miles (1170 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
$124 Average price Cheapest | $249 Average price | $384 Average price |
30h 20m Average total duration 29h 50m Onboard + 30m Additional time* | 17h 28m Average total duration 16h 58m Onboard + 30m Additional time* | 7h 10m Average total duration Fastest 4h 10m Onboard + 3h 0m Additional time* |
Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Rochester, NY to St. Louis, MO is a bus with an average price of $124 (€101).
This is compared to other travel options from Rochester, NY to St. Louis, MO:
A bus is $125 (€103) less than a train for this route with tickets for a train from Rochester, NY to St. Louis, MO costing on average $249 (€204).
A bus is $260 (€213) less than a flight for this route with tickets for a flight from Rochester, NY to St. Louis, MO costing on average $384 (€314).
The fastest way to travel from Rochester, NY to St. Louis, MO is by flight with an average journey time of 4h 10m.
Other travel options to St. Louis, MO take longer:
Train takes on average 16h 58m.
Bus takes on average 29h 50m.
It's helpful to compare your options as there are 3 ways to travel between Rochester, NY and St. Louis, MO including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Rochester, NY to St. Louis, MO among Omio's users.
Rochester, NY to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:10AM | Arrival Time 06:25AM | Duration 25h15 | Departure days Mon, Tue, Wed, Fri | Cheapest price $108 |
Operator Greyhound | Departure Time 10:10AM | Arrival Time 11:25AM | Duration 25h15 | Departure days Thu, Sat, Sun | Cheapest price $125 |
Operator Greyhound | Departure Time 11:10AM | Arrival Time 12:25PM | Duration 25h15 | Departure days Sat, Sun | Cheapest price $111 |
Operator Greyhound | Departure Time 09:15PM | Arrival Time 11:15PM | Duration 27h00 | Departure days Mon, Tue, Wed, Fri | Cheapest price $106 |
Live departures
Rochester, NY to St. Louis, MO bus times
The table below shows live departures for Rochester, NY to St. Louis, MO buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 11:10 AM Rochester, NY | 25h15 | 12:25 PM St. Louis, MO | 0 transfersDirect | |
| Sunday, June 21 | |||||
| 10:10 AM Rochester, NY | 25h15 | 11:25 AM St. Louis, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rochester, NY to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Rochester, NY to St. Louis, MO buses with Omio?
Greyhound as well as Trailways offer buses services from Rochester, NY to St. Louis, MO.
Omio is an official ticket reseller for all your travel options from Rochester, NY to St. Louis, MO.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of Trailways to find the best option for your trip from Rochester, NY to St. Louis, MO.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rochester, NY to St. Louis, MO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rochester, NY to St. Louis, MO.
Journey information
Overview: Bus from Rochester, NY to St. Louis, MO
USAUSA
Buses from Rochester, NY to St. Louis, MO run on average 3 times per day, taking around 29h 50m. Cheap bus tickets for this journey start at $108 (€88) if you book in advance.
The earliest bus runs at 06:10, the last at 23:50. The fastest bus covers the 727 miles (1170 km) distance in 25h 15m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 727 miles (1170 km) |
Average bus duration 29h 50m |
Cheapest ticket price $108 (€88) |
Buses per day 3 |
Fastest bus 25h 15m |
First bus 6:10 AM |
Last bus 11:50 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, Trailways from Rochester, NY to St. Louis, MOYou can travel by bus between Rochester, NY to St. Louis, MO with Greyhound, Trailways for as low as $108 (€88). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
25h 15m
Cheapest Price
$108 (€88)
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Trailways
Luggage & cancellation policy
Average Duration
19h 50m
Cheapest Price
$237 (€194)
Trailways frequency
1 a day
Complete guide to St. Louis
Things to do in St. Louis
Discover the best of St. Louis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis trip today.
- Must visit
City Museum
Highly original museum and artist-built environment with architectural salvage, tunnels, slides, and installations. One of the city’s most distinctive and widely shared attractions.
- Recommended
Missouri History Museum
History museum in Forest Park covering St. Louis, Missouri, and regional stories through permanent and rotating exhibitions. Well suited for visitors wanting local context.
- Must visit
Forest Park
One of the largest urban parks in the United States, home to major institutions, lakes, trails, and broad green spaces. Essential for first-time visitors.
- Must visit
Gateway Arch National Park Grounds
Riverfront grounds around the Arch with lawns, paths, and strong skyline views, useful for walking and iconic photos.
- Recommended
The Delmar Loop
Lively entertainment and walking district known for music venues, public art, shops, and the St. Louis Walk of Fame.
- Vegetarian
St. Louis-Style Pizza
A local pizza style with a very thin, cracker-like crust, cut into squares and traditionally topped with Provel cheese. It is one of the city’s signature foods.
Toasted Ravioli
Breaded and fried meat- or cheese-filled ravioli, usually served with marinara sauce. This St. Louis Italian-American specialty is strongly associated with The Hill neighborhood.
- Vegetarian
Gooey Butter Cake
A rich, dense cake with a buttery base and sweet cream cheese-like topping. It is one of the most famous desserts identified with St. Louis.
Charlie Gitto's On The Hill
A long-established Italian restaurant on The Hill, known for classic red-sauce dishes, toasted ravioli, and an old-school fine dining feel.
Ted Drewes Frozen Custard
An iconic St. Louis custard stand famous for thick concretes and nostalgic roadside charm. A must for trying the city’s best-known frozen treat.
Sidney Street Cafe
A respected contemporary American restaurant known for refined cooking, strong wine service, and a polished neighborhood setting.
United States Dollar
Generally moderate by U.S. standards. Hotels and attractions are often reasonable, while dining costs vary by neighborhood and venue.
Average meal costs
- Budget
- USD 10-18 for fast food or casual spots.
- Mid-range
- USD 20-40 per person at a mid-range restaurant.
- Fine dining
- USD 70+ per person before drinks and tip.
- Coffee
- USD 3-6 for regular coffee or a latte.
Tipping culture
Tip 18-20% at restaurants. Tip USD 1-2 per drink at bars, round up taxis, and tip hotel staff and delivery drivers.
FAQs: Bus from Rochester, NY to St. Louis, MO
Find answers to the most common questions about traveling from Rochester, NY to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Rochester, NY to St. Louis, MO can start from as little as $108 (€88) when you book in advance. The average bus ticket price for Rochester, NY to St. Louis, MO is $124 (€101) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Rochester, NY to St. Louis, MO is 25h 15m to travel the 727 miles (1170 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Rochester, NY to St. Louis, MO leaves at 6:10 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Rochester, NY to St. Louis, MO leaves at 11:50 PM.
There are 3 buses a day from Rochester, NY to St. Louis, MO which require at least one change with Greyhound, Trailways. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Rochester, NY to St. Louis, MO, you can count on Greyhound, Trailways for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Rochester, NY and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
A trip to St. Louis, MO from Rochester, NY is worth doing but not as a day trip with a journey time of 25h 15m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Rochester, NY to St. Louis, MO is February.
It's helpful to compare your options as there are 3 ways to travel between Rochester, NY and St. Louis, MO including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Rochester, NY to St. Louis, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Rochester, NY to St. Louis, MO for bus company Greyhound.
Whether you can cancel your bus ticket from Rochester, NY to St. Louis, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Rochester, NY to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Rochester, NY to St. Louis, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Rochester, NY to St. Louis, MO:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Rochester, NY to St. Louis, MO.
You can reserve your seat on the bus from Rochester, NY to St. Louis, MO with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Rochester, NY to St. Louis, MO with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Rochester, NY to St. Louis, MO with the following bus company: Greyhound.
Since neither Rochester, NY nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the train as it is the most popular way to get from Rochester, NY to St. Louis, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Rochester, NY to St. Louis, MO
Rochester
St. Louis
The major bus station for departures in Rochester is Rochester, Pleasant St (Greyhound Stop). Find all the information you need to know about services, amenities and connections at Rochester, Pleasant St (Greyhound Stop) for your trip from Rochester to St. Louis.
Rochester, Pleasant St (Greyhound Stop)
information
The major bus station for arrivals in St. Louis is St. Louis, S 15th St (Civic center). Find all the information you need to know about services, amenities and connections at St. Louis, S 15th St (Civic center) for your trip to St. Louis from Rochester.
St. Louis, S 15th St (Civic center)
information
More options for your journey from Rochester, NY to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Rochester, NY
Most popular bus connections to St. Louis, MO
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