The cheapest and fastest buses from Rome to Karlsruhe
Cheapest price
$58
Average price
$77
Fastest journey
17 h 35 m
Average duration
18 h 23 m
Buses per day
8
Distance
852 km
The best way to find a cheap bus ticket from Rome to Karlsruhe is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Karlsruhe will cost around $77 if you buy it on the day, but the cheapest tickets can be found for only $58.
Of the 8 buses that leave Rome for Karlsruhe on Thu, May 28, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 28 the direct buses cover the 852 km distance in an average of 18 h 23 m but if you time it right, some buses will get you there in just 17 h 35 m .
On Thu, May 28 the slowest buses will take 19 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
12:05 PM19h15Rome7:20 AMKarlsruhe$581One-way0 transfers
2:35 PM18h35Rome9:10 AMKarlsruhe$681One-way0 transfers
3:35 PM18h35Rome10:10 AMKarlsruhe$681One-way0 transfers
8:00 PM22h27Rome6:27 PMKarlsruhe$691One-way0 transfers
8:45 PM17h55Rome2:40 PMKarlsruhe$761One-way0 transfers
8:10 AM17h35Rome1:45 AMKarlsruhe$941One-way0 transfers
8:45 PM17h55Rome2:40 PMKarlsruhe$761One-way0 transfers
3:35 PM18h35Rome10:10 AMKarlsruhe$681One-way0 transfers
2:35 PM18h35Rome9:10 AMKarlsruhe$681One-way0 transfers
12:05 PM19h15Rome7:20 AMKarlsruhe$581One-way0 transfers
Travel Information
Compare bus for Rome to Karlsruhe
Omio recommends booking the bus as it is the most popular option from Rome to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from $58. For those with little time consider booking a bus which can get you there in 17h 45m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of $58, and a bus costs an average of $58.
Distance: 529 miles (852 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
$80 Average price Cheapest | $341 Average price (fuel + tolls) |
18h 15m Average total duration Fastest 17h 45m Onboard + 30m Additional time* | 10h 50m Average total duration (door-to-door) |
0.9 - 2.1kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Tickets start at around $80 (€65) compared to roughly $341 (€275) in fuel and tolls — a saving of about $261 (€211). The journey takes 17h 45m versus 10h 50m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Rome to Karlsruhe Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:15AM | Arrival Time 08:25PM | Duration 20h10 | Departure days Fri, Sat, Sun | Cheapest price $108 |
Operator FlixBus | Departure Time 08:10AM | Arrival Time 01:45AM | Duration 17h35 | Departure days Mon, Thu | Cheapest price $92 |
Operator FlixBus | Departure Time 09:10AM | Arrival Time 02:45AM | Duration 17h35 | Departure days Mon | Cheapest price $87 |
Operator FlixBus | Departure Time 09:25AM | Arrival Time 03:10AM | Duration 17h45 | Departure days Tue, Wed, Fri, Sat, Sun | Cheapest price $115 |
Operator FlixBus | Departure Time 10:25AM | Arrival Time 07:20AM | Duration 20h55 | Departure days Mon | Cheapest price $80 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 03:45AM | Duration 17h05 | Departure days Tue, Wed, Fri, Sat, Sun | Cheapest price $88 |
Operator FlixBus | Departure Time 11:10AM | Arrival Time 06:10AM | Duration 19h00 | Departure days Sat, Sun | Cheapest price $121 |
Operator FlixBus | Departure Time 12:05PM | Arrival Time 07:20AM | Duration 19h15 | Departure days Thu | Cheapest price $58 |
Operator FlixBus | Departure Time 12:10PM | Arrival Time 08:20AM | Duration 20h10 | Departure days Tue, Wed, Fri, Sat, Sun | Cheapest price $89 |
Operator FlixBus | Departure Time 12:20PM | Arrival Time 10:23AM | Duration 22h03 | Departure days Fri | Cheapest price $162 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 10:23AM | Duration 21h38 | Departure days Fri, Sat, Sun | Cheapest price $120 |
Operator FlixBus | Departure Time 01:00PM | Arrival Time 09:45AM | Duration 20h45 | Departure days Tue, Wed, Fri, Sat, Sun | Cheapest price $100 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 08:20AM | Duration 19h15 | Departure days Tue, Wed, Fri, Sat, Sun | Cheapest price $115 |
Operator FlixBus | Departure Time 02:35PM | Arrival Time 09:10AM | Duration 18h35 | Departure days Mon, Thu | Cheapest price $68 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 10:23AM | Duration 19h38 | Departure days Tue, Sun | Cheapest price $107 |
Operator FlixBus | Departure Time 03:35PM | Arrival Time 10:10AM | Duration 18h35 | Departure days Mon, Thu | Cheapest price $62 |
Operator FlixBus | Departure Time 03:45PM | Arrival Time 10:23AM | Duration 18h38 | Departure days Sat, Sun | Cheapest price $107 |
Operator FlixBus | Departure Time 04:35PM | Arrival Time 11:10AM | Duration 18h35 | Departure days Tue, Wed, Fri, Sat, Sun | Cheapest price $68 |
Operator FlixBus | Departure Time 05:00PM | Arrival Time 03:26PM | Duration 22h26 | Departure days Tue, Fri, Sun | Cheapest price $110 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 12:10PM | Duration 18h45 | Departure days Tue, Wed, Fri, Sat, Sun | Cheapest price $100 |
Operator FlixBus | Departure Time 07:00PM | Arrival Time 05:49PM | Duration 22h49 | Departure days Thu | Cheapest price $97 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 06:27PM | Duration 22h27 | Departure days Tue, Wed, Thu, Fri, Sat, Sun | Cheapest price $69 |
Operator FlixBus | Departure Time 08:45PM | Arrival Time 02:40PM | Duration 17h55 | Departure days Thu | Cheapest price $76 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 07:27PM | Duration 22h27 | Departure days Sat | Cheapest price $172 |
Operator FlixBus | Departure Time 09:35PM | Arrival Time 07:40PM | Duration 22h05 | Departure days Mon | Cheapest price $69 |
Operator FlixBus | Departure Time 09:45PM | Arrival Time 03:35PM | Duration 17h50 | Departure days Tue, Wed, Fri, Sat, Sun | Cheapest price $89 |
Operator FlixBus | Departure Time 10:35PM | Arrival Time 07:25PM | Duration 20h50 | Departure days Thu | Cheapest price $82 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 07:35PM | Duration 20h40 | Departure days Wed, Fri, Sat, Sun | Cheapest price $126 |
Operator Marino Autolinee | Departure Time 11:00PM | Arrival Time 05:05PM | Duration 18h05 | Departure days Tue | Cheapest price $177 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 08:25PM | Duration 20h50 | Departure days Wed, Fri, Sat, Sun | Cheapest price $95 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 08:25PM | Duration 20h35 | Departure days Wed, Fri, Sat, Sun | Cheapest price $97 |
Live departures
Rome to Karlsruhe bus times
The table below shows live departures for Rome to Karlsruhe buses for today, Wednesday, May 27. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 9:25 AM Roma, Autostazione Tiburtina | 17h45 | 3:10 AM Karlsruhe Hbf | 1 transfer | |
FlixBus · FlixBus | 10:40 AM Roma, Autostazione Tiburtina | 17h05 | 3:45 AM Karlsruhe Hbf | 1 transfer | |
FlixBus · FlixBus | 12:10 PM Roma, Autostazione Tiburtina | 20h10 | 8:20 AM Karlsruhe Hbf | 1 transfer | |
FlixBus · FlixBus | 1:00 PM Roma, Autostazione Tiburtina | 20h45 | 9:45 AM Karlsruhe Hbf | 1 transfer | |
FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 19h15 | 8:20 AM Karlsruhe Hbf | 1 transfer | |
FlixBus | 4:35 PM Roma, Autostazione Tiburtina | 18h35 | 11:10 AM Karlsruhe Hbf | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 18h45 | 12:10 PM Karlsruhe Hbf | 2 transfers | |
FlixBus · FlixBus | 8:00 PM Roma, Autostazione Tiburtina | 19h00 | 3:00 PM Karlsruhe Hbf | 1 transfer | |
FlixBus · FlixBus+ FlixTrain | 8:00 PM Roma, Autostazione Tiburtina | 18h21 | 2:21 PM Karlsruhe Hbf | 2 transfers | |
FlixBus · FlixBus | 9:45 PM Roma, Autostazione Tiburtina | 17h50 | 3:35 PM Karlsruhe Hbf | 1 transfer | |
FlixBus · FlixBus | 10:55 PM Roma, Autostazione Tiburtina | 20h40 | 7:35 PM Karlsruhe Hbf | 1 transfer | |
FlixBus · FlixBus | 11:35 PM Roma, Autostazione (Metro Anagnina) | 20h50 | 8:25 PM Karlsruhe Hbf | 1 transfer | |
FlixBus · FlixBus | 11:50 PM Roma, Autostazione Tiburtina | 20h35 | 8:25 PM Karlsruhe Hbf | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Karlsruhe by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 28
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May 31
Jun 01
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Jun 10
Why should you book Rome to Karlsruhe buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Marino Autolinee to find the best option for your trip from Rome to Karlsruhe.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Marino Autolinee to find the best option for your trip from Rome to Karlsruhe.
Journey information
Overview: Bus from Rome to Karlsruhe
Buses from Rome to Karlsruhe run on average 13 times per day, taking around 17h 45m. Cheap bus tickets for this journey start at $58 (€47) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 529 miles (852 km) distance in 17h 5m.
Distance 529 miles (852 km) |
Average bus duration 17h 45m |
Cheapest ticket price $58 (€47) |
Buses per day 13 |
Direct buses 1 |
Fastest bus 17h 5m |
First bus 12:05 AM |
Last bus 11:55 PM |
Cheapest Month Dec |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 7 days |
Bus providers: FlixBus, Marino Autolinee from Rome to KarlsruheYou can travel by bus between Rome to Karlsruhe with FlixBus, Marino Autolinee for as low as $58 (€47). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Marino Autolinee
FAQs: Bus from Rome to Karlsruhe
Find answers to the most common questions about traveling from Rome to Karlsruhe by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Karlsruhe, this guide helps you travel smarter and with confidence.

- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Rome to Karlsruhe
More options for your journey from Rome to Karlsruhe
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