- Must visit
Badisches Landesmuseum
Major regional museum inside Karlsruhe Palace, with archaeology, applied arts, and cultural history collections.
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The cheapest and fastest buses from Rome to Karlsruhe
Showing times and prices for Jul 15
Cheapest price
$67
Average price
$90
Fastest journey
17 h 5 m
Average duration
17 h 55 m
Buses per day
13
Distance
852 km
Cheap tickets
The best way to find a cheap bus ticket from Rome to Karlsruhe is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Karlsruhe will cost around $90 if you buy it on the day, but the cheapest tickets can be found for only $67.
Fast buses
Of the 13 buses that leave Rome for Karlsruhe on Wed, Jul 15, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jul 15 the direct buses cover the 852 km distance in an average of 17 h 55 m but if you time it right, some buses will get you there in just 17 h 5 m .
On Wed, Jul 15 the slowest buses will take 18 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus4:35 PM18h35Roma, Autostazione Tiburtina11:10 AMKarlsruhe Hbf$671One-way0 transfers- FlixBus · FlixBus10:40 AM17h05Roma, Autostazione Tiburtina3:45 AMKarlsruhe Hbf$791One-way1 transfer
- FlixBus · FlixBus12:10 PM20h10Roma, Autostazione Tiburtina8:20 AMKarlsruhe Hbf$791One-way1 transfer
- FlixBus · FlixBus9:45 PM17h50Roma, Autostazione Tiburtina3:35 PMKarlsruhe Hbf$811One-way1 transfer
- FlixBus · FlixBus11:35 PM21h25Roma, Autostazione (Metro Anagnina)9:00 PMKarlsruhe Hbf$821One-way1 transfer
- FlixBus · FlixBus10:40 AM17h05Roma, Autostazione Tiburtina3:45 AMKarlsruhe Hbf$791One-way1 transfer
- FlixBus · FlixBus9:25 AM17h45Roma, Autostazione Tiburtina3:10 AMKarlsruhe Hbf$921One-way1 transfer
- FlixBus · FlixBus9:45 PM17h50Roma, Autostazione Tiburtina3:35 PMKarlsruhe Hbf$811One-way1 transfer
- FlixBus · FlixBus+
FlixTrain8:00 PM18h21Roma, Autostazione Tiburtina2:21 PMKarlsruhe Hbf$951One-way2 transfers - FlixBus4:35 PM18h35Roma, Autostazione Tiburtina11:10 AMKarlsruhe Hbf$671One-way0 transfers
Travel Information
Compare bus for Rome to Karlsruhe
Omio recommends booking the bus as it is the most popular option from Rome to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from $57. For those with little time consider booking a bus which can get you there in 17h 45m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of $57, and a bus costs an average of $57.
Distance: 529 miles (852 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
$79 Average price Cheapest | $334 Average price (fuel + tolls) |
18h 15m Average total duration Fastest 17h 45m Onboard + 30m Additional time* | 10h 50m Average total duration (door-to-door) |
0.9 - 2.1kg CO2 emissions Lowest | - CO2 emissions |
Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Rome to Karlsruhe is a bus with an average price of $79 (€65).
The fastest way to travel from Rome to Karlsruhe is by bus with an average journey time of 17h 45m.
Yes, you can take a bus between Rome and Karlsruhe.
We recommend using the bus as it is the most popular way to get from Rome to Karlsruhe among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $79 (€65) compared to roughly $334 (€275) in fuel and tolls — a saving of about $255 (€211). The journey takes 17h 45m versus 10h 50m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Direct services are operated by FlixBus.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Rome to Karlsruhe Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:15AM | Arrival Time 09:00PM | Duration 20h45 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $87 |
Operator FlixBus | Departure Time 09:25AM | Arrival Time 03:10AM | Duration 17h45 | Departure days Everyday | Cheapest price $92 |
Operator FlixBus | Departure Time 10:40AM | Arrival Time 03:45AM | Duration 17h05 | Departure days Everyday | Cheapest price $76 |
Operator FlixBus | Departure Time 11:00AM | Arrival Time 06:10AM | Duration 19h10 | Departure days Sat, Sun | Cheapest price $115 |
Operator FlixBus | Departure Time 12:10PM | Arrival Time 08:20AM | Duration 20h10 | Departure days Everyday | Cheapest price $79 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 10:23AM | Duration 21h38 | Departure days Mon, Tue, Thu, Fri, Sun | Cheapest price $111 |
Operator FlixBus | Departure Time 01:00PM | Arrival Time 09:45AM | Duration 20h45 | Departure days Everyday | Cheapest price $76 |
Operator FlixBus | Departure Time 01:05PM | Arrival Time 08:20AM | Duration 19h15 | Departure days Everyday | Cheapest price $85 |
Operator FlixBus | Departure Time 02:45PM | Arrival Time 10:23AM | Duration 19h38 | Departure days Mon, Tue, Fri | Cheapest price $109 |
Operator FlixBus | Departure Time 03:45PM | Arrival Time 10:23AM | Duration 18h38 | Departure days Thu, Sun | Cheapest price $100 |
Operator FlixBus | Departure Time 04:35PM | Arrival Time 11:10AM | Duration 18h35 | Departure days Everyday | Cheapest price $67 |
Operator FlixBus | Departure Time 05:00PM | Arrival Time 03:26PM | Duration 22h26 | Departure days Mon, Tue, Fri, Sun | Cheapest price $76 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 12:10PM | Duration 18h45 | Departure days Everyday | Cheapest price $76 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 03:00PM | Duration 19h00 | Departure days Everyday | Cheapest price $92 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 07:27PM | Duration 22h27 | Departure days Thu, Sat | Cheapest price $89 |
Operator FlixBus | Departure Time 09:45PM | Arrival Time 03:35PM | Duration 17h50 | Departure days Everyday | Cheapest price $77 |
Operator FlixBus | Departure Time 10:55PM | Arrival Time 07:35PM | Duration 20h40 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $107 |
Operator Marino Autolinee | Departure Time 11:00PM | Arrival Time 05:05PM | Duration 18h05 | Departure days Tue, Thu | Cheapest price $126 |
Operator FlixBus | Departure Time 11:35PM | Arrival Time 09:00PM | Duration 21h25 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $82 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 09:00PM | Duration 21h10 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $83 |
Live departures
Rome to Karlsruhe bus times
The table below shows live departures for Rome to Karlsruhe buses for today, Tuesday, July 14. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus+FlixTrain | 2:45 PM Roma, Autostazione Tiburtina | 19h38 | 10:23 AM Karlsruhe Hbf | 2 transfers | |
| FlixBus | 4:35 PM Roma, Autostazione Tiburtina | 18h35 | 11:10 AM Karlsruhe Hbf | 0 transfersDirect | |
| FlixBus · FlixBus+FlixTrain | 5:00 PM Roma, Autostazione Tiburtina | 22h26 | 3:26 PM Karlsruhe Hbf | 2 transfers | |
| FlixBus · FlixBus · FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 18h45 | 12:10 PM Karlsruhe Hbf | 2 transfers | |
| FlixBus · FlixBus | 8:00 PM Roma, Autostazione Tiburtina | 19h00 | 3:00 PM Karlsruhe Hbf | 1 transfer | |
| FlixBus · FlixBus | 9:45 PM Roma, Autostazione Tiburtina | 17h50 | 3:35 PM Karlsruhe Hbf | 1 transfer | |
 054 · 253 | 11:00 PM Roma, Autostazione Tiburtina | 18h05 | 5:05 PM Karlsruhe, Hinterm Hauptbahnhof (Südeingang) | 1 transfer | |
| Wednesday, July 15 | |||||
| FlixBus · FlixBus | 9:25 AM Roma, Autostazione Tiburtina | 17h45 | 3:10 AM Karlsruhe Hbf | 1 transfer | |
| FlixBus · FlixBus | 10:40 AM Roma, Autostazione Tiburtina | 17h05 | 3:45 AM Karlsruhe Hbf | 1 transfer | |
| FlixBus · FlixBus | 12:10 PM Roma, Autostazione Tiburtina | 20h10 | 8:20 AM Karlsruhe Hbf | 1 transfer | |
| FlixBus · FlixBus | 1:00 PM Roma, Autostazione Tiburtina | 20h45 | 9:45 AM Karlsruhe Hbf | 1 transfer | |
| FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 19h15 | 8:20 AM Karlsruhe Hbf | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Karlsruhe by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Rome to Karlsruhe buses with Omio?
FlixBus as well as Marino Autolinee offer buses services from Rome to Karlsruhe.
Omio is an official ticket reseller for all your travel options from Rome to Karlsruhe.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Marino Autolinee to find the best option for your trip from Rome to Karlsruhe.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Marino Autolinee to find the best option for your trip from Rome to Karlsruhe.
Journey information
Overview: Bus from Rome to Karlsruhe
Italy
Germany
Buses from Rome to Karlsruhe run on average 13 times per day, taking around 17h 45m. Cheap bus tickets for this journey start at $57 (€47) if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 529 miles (852 km) distance in 17h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 529 miles (852 km) |
Average bus duration 17h 45m |
Cheapest ticket price $57 (€47) |
Buses per day 13 |
Direct buses 1 |
Fastest bus 17h 5m |
First bus 12:05 AM |
Last bus 11:55 PM |
Cheapest Month Dec |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Wed |
Best time to book 7 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus, Marino Autolinee from Rome to KarlsruheYou can travel by bus between Rome to Karlsruhe with FlixBus, Marino Autolinee for as low as $57 (€47). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
17h 5m
Cheapest Price
$57 (€47)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Marino Autolinee
About
MarinoBus is an Italian bus company with more than 200 destinations and 6,000 connections across Italy and Europe. Originally focused on Basilicata and Apulia, its network has expanded to cover the rest of Italy as well as Switzerland, France, Germany, and Luxembourg. All MarinoBus coaches are equipped with spacious reclining seats, air conditioning, onboard restrooms, WiFi, minibars, and color TVs. For your next trip, you can book the standard ticket, which includes one piece of hand luggage and up to two checked bags per passenger
Luggage & cancellation policy
Average Duration
18h 5m
Cheapest Price
$91 (€75)
Luggage included
One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
10€ per additional bag up to 20 kg.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.
Complete guide to Karlsruhe
Things to do in Karlsruhe
Discover the best of Karlsruhe — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Karlsruhe trip today.
- Must visit
ZKM | Center for Art and Media
Leading center for art and media with exhibitions on digital culture, contemporary art, and immersive technology.
- Recommended
Staatliche Kunsthalle Karlsruhe
State art museum showing works from old masters to modern periods in a distinguished historic setting.
- Must visit
Marktplatz
Grand central square lined with major buildings and the city pyramid, ideal for orientation and architecture.
- Must visit
Schlossgarten
Large landscaped park behind the palace with tree-lined paths, gardens, and space for relaxed walks.
- Must visit
Turmberg
Wooded hill and lookout area above Durlach, popular for walks, sunsets, and broad views of the Rhine plain.
- Vegetarian
- Gluten-free
Badische Kartoffelsuppe
A hearty Baden potato soup, often finished with cream and herbs. It is a regional comfort dish common across Baden homes and inns.
Flädlesuppe
Thin pancakes sliced into strips and served in clear beef broth. Popular in Baden and Swabia, it is a classic starter in traditional restaurants.
- Vegetarian
Spätzle
Handmade egg noodles from nearby Swabian tradition, often served with cheese or lentils. Widely eaten in Karlsruhe and across Baden-Württemberg.
sein
Michelin-starred fine dining with creative tasting menus and polished service. Best for a high-end meal showcasing modern German cuisine.
Oberländer Weinstube
Traditional Baden restaurant in a historic setting, known for regional classics, seasonal menus, and a refined but welcoming atmosphere.
Vogelbräu Karlsruhe
Established brewery venue serving house beers and hearty German dishes. Lively, casual atmosphere popular for local food and social evenings.
Euro (€)
Moderate for Germany. Hotels and dining are cheaper than Munich or Frankfurt, while transit is affordable and many casual meals stay reasonably priced.
Average meal costs
- Budget
- €8-12 for fast food or simple lunch.
- Mid-range
- €18-30 per person for a restaurant meal.
- Fine dining
- €60+ per person for upscale dining.
- Coffee
- €2.80-4.50 for a cappuccino.
Tipping culture
Service is usually included, but rounding up is standard. Add about 5-10% in restaurants, round up taxi fares, and leave small change at cafes.
FAQs: Bus from Rome to Karlsruhe
Find answers to the most common questions about traveling from Rome to Karlsruhe by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Karlsruhe, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Rome to Karlsruhe can start from as little as $57 (€47) when you book in advance. The average bus ticket price for Rome to Karlsruhe is $79 (€65) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Rome to Karlsruhe is 17h 5m to travel the 529 miles (852 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Rome to Karlsruhe leaves at 12:05 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Rome to Karlsruhe leaves at 11:55 PM.
Yes, there are 1 direct buses a day from Rome to Karlsruhe with FlixBus. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Rome to Karlsruhe, you can count on FlixBus, Marino Autolinee for the best way to get you to Karlsruhe. You can also check all possible bus companies who offer a service between Rome and Karlsruhe and compare the amenities they offer before buying a bus ticket.
A trip to Karlsruhe from Rome is worth doing but not as a day trip with a journey time of 17h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Rome to Karlsruhe is December.
Yes, you can take a bus between Rome and Karlsruhe.
Yes, the following accessibility options are available when taking the bus from Rome to Karlsruhe:
- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Rome to Karlsruhe for bus company FlixBus, Marino Autolinee.
Whether you can cancel your bus ticket from Rome to Karlsruhe depends on the bus companies:
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus, Marino Autolinee.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Rome to Karlsruhe.
Yes, the following luggage options are included when booking a bus ticket from Rome to Karlsruhe:
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Rome to Karlsruhe:
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Rome to Karlsruhe. The following conditions apply:
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Rome to Karlsruhe with the following bus company: FlixBus, Marino Autolinee
Yes, there are USB plugs on board the bus from Rome to Karlsruhe with the following bus company: FlixBus, Marino Autolinee.
Yes, there is Wifi on board the bus from Rome to Karlsruhe with the following bus company: FlixBus, Marino Autolinee.
Since both Rome and Karlsruhe are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the bus as it is the most popular way to get from Rome to Karlsruhe among Omio's users.
Germany uses the euro (€) as its currency. Travelers generally find it convenient to use cards, especially contactless payments, in cities and larger establishments. However, cash is still widely accepted and sometimes preferred in smaller shops, markets, and rural areas. Carrying some cash is recommended for flexibility.
In Karlsruhe, travelers should be cautious of pickpocketing, especially in crowded areas like public transport and popular tourist spots. Scams involving fake charity collectors and overcharging in taxis can occur, so it's advisable to use official transportation services and verify fares beforehand. Staying aware of surroundings and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
More options for your journey from Rome to Karlsruhe
Here are some other resources that might have the information you need
Most popular buses to and from Karlsruhe and Rome
Most popular bus connections to Karlsruhe
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