- Must visit
Vatican Museums
A vast complex of papal collections with masterpieces from antiquity to the Renaissance. A global essential for art, history, and iconic galleries.
Cheapest price on Sep 08
$13
Average ticket price on Sep 08
$15
Fastest journey on Sep 08
4 h 45 m
Average journey duration on Sep 08
5 h 24 m
Buses on Sep 08
4
Distance
262 km
The best way to find a cheap bus ticket from Pisa to Vatican is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Vatican will cost around $15 if you buy it on the day, but the cheapest tickets can be found for only $13.
On Tue, Sep 08, we found 4 buses from Pisa to Vatican, including 4 direct services.
On Tue, Sep 08 the direct buses cover the 262 km distance in an average of 5 h 24 m but if you time it right, some buses will get you there in just 4 h 45 m .
On Tue, Sep 08 the slowest buses will take 6 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








Omio recommends booking the train as it is the most popular option from Pisa to Vatican among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $30 For those with little time, consider booking a train, which has an average total journey time of 3h 49m. Average ticket prices depend on the travel mode: a bus costs an average of $30, while a flight costs an average of $489.
Distance: 162 miles (262 km)
| Bus | Most popular Train | Flight |
|---|---|---|
$30 Average price Cheapest | $44 Average price | $489 Average price |
5h 33m Average total duration 5h 3m Onboard + 30m Additional time* | 3h 49m Average total duration Fastest 3h 19m Onboard + 30m Additional time* | 5h 37m Average total duration 3h 37m Onboard + 2h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Pisa to Vatican:
A bus is $15 (€12) less than a train for this route with tickets for a train from Pisa to Vatican costing on average $44 (€36).
A bus is $459 (€371) less than a flight for this route with tickets for a flight from Pisa to Vatican costing on average $489 (€395).
Other travel options to Vatican take longer:
Flight takes on average 3h 37m.
Bus takes on average 5h 3m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:05AM | Arrival Time 08:50AM | Duration 4h45 | Departure days Mon, Tue, Sun | Cheapest price $16 |
Operator FlixBus | Departure Time 05:05AM | Arrival Time 09:50AM | Duration 4h45 | Departure days Mon, Fri | Cheapest price $16 |
Operator FlixBus | Departure Time 06:10AM | Arrival Time 12:20PM | Duration 6h10 | Departure days Mon, Tue, Wed, Sat, Sun | Cheapest price $13 |
Operator FlixBus | Departure Time 06:15AM | Arrival Time 12:20PM | Duration 6h05 | Departure days Wed | Cheapest price $14 |
Operator Marino Autolinee | Departure Time 06:20AM | Arrival Time 12:20PM | Duration 6h00 | Departure days Sat | Cheapest price $21 |
Operator Marino Autolinee | Departure Time 07:20AM | Arrival Time 01:20PM | Duration 6h00 | Departure days Wed, Fri, Sun | Cheapest price $20 |
Operator Regionale | Departure Time 07:45AM | Arrival Time 01:27PM | Duration 5h42 | Departure days Thu | Cheapest price $31 |
Operator Marino Autolinee | Departure Time 08:20AM | Arrival Time 02:20PM | Duration 6h00 | Departure days Thu | Cheapest price $30 |
Operator FlixBus | Departure Time 11:25AM | Arrival Time 04:35PM | Duration 5h10 | Departure days Fri | Cheapest price $21 |
Operator FlixBus | Departure Time 12:25PM | Arrival Time 05:35PM | Duration 5h10 | Departure days Tue | Cheapest price $16 |
Operator FlixBus | Departure Time 04:25PM | Arrival Time 09:35PM | Duration 5h10 | Departure days Mon | Cheapest price $20 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 12:35AM | Duration 4h35 | Departure days Mon | Cheapest price $17 |
Operator FlixBus | Departure Time 10:25PM | Arrival Time 03:55AM | Duration 5h30 | Departure days Mon, Sat | Cheapest price $16 |
The table below shows live departures for Pisa to Vatican buses for tomorrow, Tuesday, September 8. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:05 AM Pisa | 4h45 | 8:50 AM Vatican | 0 transfersDirect | |
![]() | 6:10 AM Pisa | 6h10 | 12:20 PM Vatican | 0 transfersDirect | |
![]() | 12:25 PM Pisa | 5h10 | 5:35 PM Vatican | 0 transfersDirect | |
![]() | 10:25 PM Pisa | 5h30 | 3:55 AM Vatican | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Pisa to Vatican run on average 6 times per day, taking around 5h 3m. Cheap bus tickets for this journey start at $15 (€12) if you book in advance.
There are 4 buses per day. The earliest bus runs at 00:10, the last at 23:52. The fastest bus covers the 162 miles (262 km) distance in 4h 14m.
Distance 162 miles (262 km) |
Average bus duration 5h 3m |
Cheapest ticket price $15 (€12) |
Buses per day 6 |
Direct buses 4 |
Fastest bus 4h 14m |
First bus 12:10 AM |
Last bus 11:52 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Oct - Dec |
Busiest Day Fri |
Least Busy Day Thu |
Best time to book 63 days |
Discover the best of Vatican — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Vatican trip today.
A vast complex of papal collections with masterpieces from antiquity to the Renaissance. A global essential for art, history, and iconic galleries.
Home to Raphael’s fresco cycles, including The School of Athens. These rooms are among the Vatican’s greatest artistic highlights and a major museum draw.
This gallery presents maps of Italy in a long frescoed corridor. It is both visually striking and historically fascinating within the museum route.
This broad ceremonial piazza is Vatican City’s main gathering place, offering classic basilica views, fountains, and a powerful sense of scale.
Bernini’s embracing colonnades create one of the world’s great urban spaces. Walk here for architecture, symmetry, and changing light across the square.
The basilica dome terraces deliver one of Rome’s most famous viewpoints, with close-up architecture and sweeping city vistas.
Cacio e Pepe is a Roman pasta with Pecorino Romano and black pepper. It is a local staple around Vatican City for its simplicity and strong regional identity.
Carbonara is pasta with egg, Pecorino Romano, guanciale, and pepper. It is one of Rome's most famous dishes and widely served in trattorias near the Vatican.
Amatriciana is pasta with tomato, guanciale, and Pecorino Romano. Though linked to Amatrice, it is a classic Roman favorite commonly eaten near the Vatican.
Traditional Roman trattoria in Prati known for pasta classics and a lively local atmosphere, convenient for Vatican visitors.
Long-established Roman restaurant near the Vatican serving cacio e pepe, amatriciana, and other regional staples in a classic setting.
Refined dining room in Prati with polished Roman and Italian dishes, strong wine list, and a more upscale atmosphere.
Very high tourist demand and limited lodging nearby make stays pricey. Dining is similar to central Rome, while transit costs are low if using Rome buses and metro.
Service may be included. Round up or leave 5-10% at restaurants for good service. Taxis are usually rounded up. Small change is fine at cafés.
Official public transport app
Vatican City Railway Station -> Piazza Venezia
Find answers to the most common questions about traveling from Pisa to Vatican by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Vatican, this guide helps you travel smarter and with confidence.

Most Pisa to Vatican buses use the Pisa, Via delle Fiamme Gialle (Park Pietrasantina) to Roma, Autostazione Tiburtina station pair. Use this guide to compare Pisa and Vatican bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) is 1 km from Pisa city centre. Public transport options include:
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, Ticket Office, Bike Parking, and Bike Rental.
Wi-Fi is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina). ATMs are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Ticket office support is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Parking, Taxis, WC.
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): The station is accessible for people with reduced mobility.
Pisa (Pisamover via San Giusto/Aurelia) is 1 km from Pisa city centre. Public transport options include:
Pisa (Pisamover via San Giusto/Aurelia) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Pisa (Pisamover via San Giusto/Aurelia). ATMs are available at Pisa (Pisamover via San Giusto/Aurelia).
Ticket office support is available at Pisa (Pisamover via San Giusto/Aurelia).
Available at Pisa (Pisamover via San Giusto/Aurelia): Parking, Taxis, WC.
Accessibility facilities are available at Pisa (Pisamover via San Giusto/Aurelia): Wheelchair accessible with assistance.
Here are some other resources that might have the information you need