- Must visit
Vatican Museums
A vast complex of papal collections with masterpieces from antiquity to the Renaissance. A global essential for art, history, and iconic galleries.
Cheapest price
$35
Average price
$35
Fastest journey
6 h
Average duration
6 h
Buses per day
1
Distance
262 km
The best way to find a cheap bus ticket from Pisa to Vatican is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Vatican will cost around $35 if you buy it on the day, but the cheapest tickets can be found for only $35.
Of the 1 buses that leave Pisa for Vatican on Sat, Jul 25, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jul 25 the direct buses cover the 262 km distance in an average of 6 h but if you time it right, some buses will get you there in just 6 h .
On Sat, Jul 25 the slowest buses will take 6 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
207
207Omio recommends booking the train as it is the most popular option from Pisa to Vatican among Omio's users. If you are prioritising price take the bus with prices starting from $10. For those with little time consider booking a train which can get you there in 3h 18m. The ticket price range depends on the travel mode: a bus costs an average of $10, and a train costs an average of $15.
Distance: 162 miles (262 km)
| Bus | Most popular Train |
|---|---|
$15 Average price Cheapest | $21 Average price |
5h 40m Average total duration 5h 10m Onboard + 30m Additional time* | 3h 48m Average total duration Fastest 3h 18m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
This is compared to other travel options from Pisa to Vatican:
A bus is $7 (€7) less than a train for this route with tickets for a train from Pisa to Vatican costing on average $21 (€21).
Other travel options to Vatican take longer:
Bus takes on average 5h 10m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:25AM | Arrival Time 05:55AM | Duration 5h30 | Departure days Fri | Cheapest price $25 |
Operator FlixBus | Departure Time 04:05AM | Arrival Time 08:50AM | Duration 4h45 | Departure days Mon, Tue, Thu, Sun | Cheapest price $13 |
Operator FlixBus | Departure Time 05:05AM | Arrival Time 09:50AM | Duration 4h45 | Departure days Mon, Thu | Cheapest price $12 |
Operator FlixBus | Departure Time 06:05AM | Arrival Time 10:50AM | Duration 4h45 | Departure days Fri | Cheapest price $21 |
Operator FlixBus | Departure Time 06:10AM | Arrival Time 12:20PM | Duration 6h10 | Departure days Mon, Tue, Wed, Sun | Cheapest price $10 |
Operator FlixBus | Departure Time 06:15AM | Arrival Time 12:20PM | Duration 6h05 | Departure days Wed | Cheapest price $11 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 01:20PM | Duration 6h05 | Departure days Fri | Cheapest price $25 |
Operator Marino Autolinee | Departure Time 07:20AM | Arrival Time 01:20PM | Duration 6h00 | Departure days Wed, Sun | Cheapest price $16 |
Operator Marino Autolinee | Departure Time 08:20AM | Arrival Time 02:20PM | Duration 6h00 | Departure days Fri, Sat | Cheapest price $26 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 04:05PM | Duration 6h25 | Departure days Fri | Cheapest price $25 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 05:50PM | Duration 5h50 | Departure days Fri | Cheapest price $32 |
Operator FlixBus | Departure Time 12:25PM | Arrival Time 05:35PM | Duration 5h10 | Departure days Tue | Cheapest price $13 |
Operator FlixBus | Departure Time 01:25PM | Arrival Time 06:35PM | Duration 5h10 | Departure days Fri | Cheapest price $26 |
Operator FlixBus | Departure Time 04:25PM | Arrival Time 09:35PM | Duration 5h10 | Departure days Mon | Cheapest price $16 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 10:35PM | Duration 5h10 | Departure days Fri | Cheapest price $18 |
Operator FlixBus | Departure Time 08:00PM | Arrival Time 12:35AM | Duration 4h35 | Departure days Mon | Cheapest price $14 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 01:35AM | Duration 4h35 | Departure days Thu | Cheapest price $13 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 02:35AM | Duration 4h35 | Departure days Fri | Cheapest price $19 |
Operator FlixBus | Departure Time 10:25PM | Arrival Time 03:55AM | Duration 5h30 | Departure days Mon, Sat | Cheapest price $13 |
The table below shows live departures for Pisa to Vatican buses for tomorrow, Saturday, July 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
207 | 8:20 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 6h00 | 2:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Pisa to Vatican run on average 9 times per day, taking around 5h 10m. Cheap bus tickets for this journey start at $10 (€10) if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:10, the last at 23:52. The fastest bus covers the 162 miles (262 km) distance in 4h 35m.
Distance 162 miles (262 km) |
Average bus duration 5h 10m |
Cheapest ticket price $10 (€10) |
Buses per day 9 |
Direct buses 6 |
Fastest bus 4h 35m |
First bus 12:10 AM |
Last bus 11:52 PM |
Cheapest Month Mar |
Cheapest Day Tue |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Wed |
Least Busy Day Fri |
Best time to book 63 days |
Discover the best of Vatican — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Vatican trip today.
A vast complex of papal collections with masterpieces from antiquity to the Renaissance. A global essential for art, history, and iconic galleries.
Home to Raphael’s fresco cycles, including The School of Athens. These rooms are among the Vatican’s greatest artistic highlights and a major museum draw.
This gallery presents maps of Italy in a long frescoed corridor. It is both visually striking and historically fascinating within the museum route.
This broad ceremonial piazza is Vatican City’s main gathering place, offering classic basilica views, fountains, and a powerful sense of scale.
Bernini’s embracing colonnades create one of the world’s great urban spaces. Walk here for architecture, symmetry, and changing light across the square.
The basilica dome terraces deliver one of Rome’s most famous viewpoints, with close-up architecture and sweeping city vistas.
Cacio e Pepe is a Roman pasta with Pecorino Romano and black pepper. It is a local staple around Vatican City for its simplicity and strong regional identity.
Carbonara is pasta with egg, Pecorino Romano, guanciale, and pepper. It is one of Rome's most famous dishes and widely served in trattorias near the Vatican.
Amatriciana is pasta with tomato, guanciale, and Pecorino Romano. Though linked to Amatrice, it is a classic Roman favorite commonly eaten near the Vatican.
Traditional Roman trattoria in Prati known for pasta classics and a lively local atmosphere, convenient for Vatican visitors.
Long-established Roman restaurant near the Vatican serving cacio e pepe, amatriciana, and other regional staples in a classic setting.
Refined dining room in Prati with polished Roman and Italian dishes, strong wine list, and a more upscale atmosphere.
Very high tourist demand and limited lodging nearby make stays pricey. Dining is similar to central Rome, while transit costs are low if using Rome buses and metro.
Service may be included. Round up or leave 5-10% at restaurants for good service. Taxis are usually rounded up. Small change is fine at cafés.
Official public transport app
Vatican City Railway Station -> Piazza Venezia
Find answers to the most common questions about traveling from Pisa to Vatican by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Vatican, this guide helps you travel smarter and with confidence.

Most Pisa to Vatican buses use the Pisa, Via delle Fiamme Gialle (Park Pietrasantina) to Roma, Autostazione Tiburtina station pair. Use this guide to compare Pisa and Vatican bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need