- Recommended
Museo Archeologico Provinciale Francesco Ribezzo
Main archaeological museum of Brindisi, known for finds from ancient Brundisium and underwater discoveries from the Adriatic.
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The cheapest and fastest buses from Palermo to Brindisi
Showing times and prices for May 25
Cheapest price
$66
Average price
$66
Fastest journey
20 h 24 m
Average duration
20 h 24 m
Buses per day
1
Distance
482 km
Cheap tickets
The best way to find a cheap bus ticket from Palermo to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Brindisi will cost around $66 if you buy it on the day, but the cheapest tickets can be found for only $66.
Fast buses
It's difficult to get from Palermo to Brindisi without transferring at least once.
FlixBus · FlixBus9:10 PM20h24Palermo, Via Tommaso Fazello (Terminal Bus)5:34 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$661One-way1 transfer
- FlixBus · FlixBus9:10 PM20h24Palermo, Via Tommaso Fazello (Terminal Bus)5:34 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$661One-way1 transfer
Travel Information
Compare bus, train, and flight for Palermo to Brindisi
Omio recommends booking the flight as it is the most popular option from Palermo to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from $38. For those with little time consider booking a flight which can get you there in 1h 39m. The ticket price range depends on the travel mode: a bus costs an average of $38, and a flight costs an average of $135.
Distance: 299 miles (482 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$75 Average price Cheapest | $185 Average price | $80 Average price | $60 Average price (fuel + tolls) |
12h 54m Average total duration 12h 24m Onboard + 30m Additional time* | 4h 39m Average total duration Fastest 1h 39m Onboard + 3h 0m Additional time* | 14h 22m Average total duration 13h 52m Onboard + 30m Additional time* | 8h 4m Average total duration (door-to-door) |
Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Palermo to Brindisi is a bus with an average price of $75 (€61).
This is compared to other travel options from Palermo to Brindisi:
A bus is $5 (€4) less than a train for this route with tickets for a train from Palermo to Brindisi costing on average $80 (€65).
A bus is $110 (€89) less than a flight for this route with tickets for a flight from Palermo to Brindisi costing on average $185 (€150).
The fastest way to travel from Palermo to Brindisi is by flight with an average journey time of 1h 39m.
Other travel options to Brindisi take longer:
Bus takes on average 12h 24m.
Train takes on average 13h 52m.
It's helpful to compare your options as there are 3 ways to travel between Palermo and Brindisi including taking a bus, train, and flight.
We recommend using the flight as it is the most popular way to get from Palermo to Brindisi among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.
You'll arrive about -5h -20m sooner (12h 24m by bus vs 8h 4m by car) and save roughly $-15.56 (€-12.59) compared to fuel and tolls ($75 (€61) vs $60 (€48)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by FlixBus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Palermo to Brindisi Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 07:10PM | Arrival Time 03:49PM | Duration 20h39 | Departure days Tue | Cheapest price $95 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 05:34PM | Duration 20h24 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price $42 |
Live departures
Palermo to Brindisi bus times
The table below shows live departures for Palermo to Brindisi buses for tomorrow, Monday, May 25. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 9:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 20h24 | 5:34 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Palermo to Brindisi by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Palermo to Brindisi buses with Omio?
FlixBus as well as Sais Autolinee or Infobus offer buses services from Palermo to Brindisi.
Omio is an official ticket reseller for all your travel options from Palermo to Brindisi.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Sais Autolinee or Infobus to find the best option for your trip from Palermo to Brindisi.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Palermo to Brindisi.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Sais Autolinee or Infobus to find the best option for your trip from Palermo to Brindisi.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Palermo to Brindisi.
Journey information
Overview: Bus from Palermo to Brindisi
ItalyItaly
Buses from Palermo to Brindisi run on average 1 times per day, taking around 12h 24m. Cheap bus tickets for this journey start at $38 (€31) but you can travel from only $33 (€27) by train.
The earliest bus runs at 04:21, the last at 23:50. The fastest bus covers the 299 miles (482 km) distance in 20h 24m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $33 (€27)
Distance 299 miles (482 km) |
Average bus duration 12h 24m |
Cheapest ticket price $38 (€31) |
Buses per day 1 |
Fastest bus 20h 24m |
First bus 4:21 AM |
Last bus 11:50 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Wed |
Best time to book 21 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $33 (€27)
Bus providers: FlixBus, Sais Autolinee, Infobus from Palermo to BrindisiYou can travel by bus between Palermo to Brindisi with FlixBus, Sais Autolinee, Infobus for as low as $33 (€27). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
20h 24m
Cheapest Price
$38 (€31)
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Sais Autolinee
About
Sais Autolinee S.p.A. is an Italian bus company founded in Enna in 1926, providing urban, suburban, and intercity bus services primarily within Sicily and connecting to other destinations in Italy. With over 90 years of experience, Sais Autolinee is a prominent mobility provider in Sicily, offering more than 70 daily departures from major cities like Catania, Palermo, and Messina. The company focuses on comfort, safety, and technological innovation, aiming to provide enjoyable travel experiences with a modern and eco-friendly fleet. Popular routes include connections between Catania, Palermo, and Messina, as well as services to Catania Airport.
Luggage & cancellation policy
Average Duration
10h 45m
Cheapest Price
$52 (€42)
Sais Autolinee frequency
1 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. No refunds for cancellations within 24 hours.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating.
Bikes
Bikes are allowed; prior reservation is recommended.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.
Infobus
About
Infobus is an international IT company that operates as an online service for finding and purchasing bus, train, and plane tickets, rather than being a bus company itself. Established in 2002, Infobus acts as an intermediary between passengers and various transport carriers, particularly helping smaller bus companies offer online booking services. They utilize their own "BusSystem" to manage routes and ticket sales globally. Infobus covers over 30 countries and 300 cities, offering a wide range of routes and daily departures. While amenities can vary by carrier, Infobus aims to provide affordable and convenient travel with features like online booking, 24/7 support, and prompt notifications.
Luggage & cancellation policy
Luggage included
One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
Additional luggage
10€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Transport for wheelchairs and mobility aids.
Bikes
Bikes are allowed; may require prior reservation and an additional fee.
Pets
Small pets allowed in carriers; larger pets may require a separate ticket.
Complete guide to Brindisi
Things to do in Brindisi
Discover the best of Brindisi — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brindisi trip today.
- Recommended
Tempietto di San Giovanni al Sepolcro Interpretive Area
Though primarily a landmark, the interior often functions as a small interpretive heritage space about medieval Brindisi and pilgrim routes.
Palazzo Granafei Nervegna
Historic palace used for exhibitions and cultural displays, often visited for temporary shows and its central location near the Roman column.
- Must visit
Scalinata Virgilio
The grand waterfront staircase by the Roman column, one of Brindisi's signature viewpoints and a favorite photo stop.
- Must visit
Lungomare Regina Margherita
Elegant seafront promenade lined with palms and harbor views, ideal for walks, sunset photos, and experiencing Brindisi's maritime character.
- Recommended
Piazza Duomo
Atmospheric cathedral square surrounded by major historic buildings, offering one of the most distinctive urban spaces in Brindisi's old town.
- Vegetarian
- Vegan
Orecchiette Alle Cime Di Rapa
Puglia’s signature ear-shaped pasta with turnip greens, olive oil, garlic, and often chili. A classic local dish strongly associated with the region around Brindisi.
- Vegetarian
- Vegan
- Gluten-free
Fave E Cicoria
A rustic Apulian staple of dried fava bean purée served with wild chicory. It is simple, traditional peasant food still loved across Brindisi and Salento.
Puccia
A round Apulian bread, usually split and filled with local ingredients such as cheese, vegetables, or cured meats. It is a popular street-food style meal in the area.
Penny
Recognized Brindisi restaurant appreciated for refined seafood cooking and a more contemporary dining style. Suitable for a higher-end meal featuring local ingredients.
Betty Cafe Ristorante
Established waterfront restaurant in Brindisi known for seafood, Apulian dishes, and views over the harbor. A polished but relaxed setting for a classic local meal.
La Locanda Del Porto
Well-known dining spot near the port with a traditional menu focused on fresh fish, pasta, and regional specialties. Popular for a pleasant maritime atmosphere.
Euro
Generally cheaper than Rome or Milan. Good value for casual dining and coffee, while hotels and waterfront restaurants cost more in peak season.
Average meal costs
- Budget
- EUR 8-15 for pizza, panini, or simple lunch.
- Mid-range
- EUR 20-35 per person for a standard restaurant meal.
- Fine dining
- EUR 50-90 per person at upscale seafood or tasting restaurants.
- Coffee
- EUR 1.20-2.50 for espresso or cappuccino.
Tipping culture
Service is often included or modest. Rounding up or leaving EUR 1-2 at cafes is enough; about 5-10% in restaurants for very good service. Taxis can be rounded up.
MyCicero
Get the appOfficial public transport app
Prices
- Single ticket
- EUR 1.00
- Day pass
- None
To the city center
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) -> Brindisi Railway Station
- Distance
- 2 km
- Travel time
- 10 min
- Buy city bus tickets before boarding; they are usually sold by tobacconists, kiosks, and authorized retailers.
- Card payment on board is not reliably available on local buses, so carry a validated paper ticket or mobile ticket before travel.
FAQs: Bus from Palermo to Brindisi
Find answers to the most common questions about traveling from Palermo to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Palermo to Brindisi can start from as little as $38 (€31) when you book in advance. The average bus ticket price for Palermo to Brindisi is $75 (€61) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Palermo to Brindisi is 20h 24m to travel the 299 miles (482 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Palermo to Brindisi leaves at 4:21 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Palermo to Brindisi leaves at 11:50 PM.
There are 1 buses a day from Palermo to Brindisi which require at least one change with FlixBus, Sais Autolinee, Infobus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Palermo to Brindisi, you can count on FlixBus, Sais Autolinee, Infobus for the best way to get you to Brindisi. You can also check all possible bus companies who offer a service between Palermo and Brindisi and compare the amenities they offer before buying a bus ticket.
Passengers board the bus most frequently from Palermo, Via Tommaso Fazello (Terminal Bus), which is located around 1 away from the city centre, and they get off the bus at Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale), located 0 away from the city centre.
A trip to Brindisi from Palermo is worth doing but not as a day trip with a journey time of 20h 24m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Palermo to Brindisi is September.
It's helpful to compare your options as there are 3 ways to travel between Palermo and Brindisi including taking a bus, train, and flight.
Yes, there are bathrooms on board the bus from Palermo to Brindisi for bus company FlixBus, Sais Autolinee, Infobus.
Yes, the following accessibility options are available when taking the bus from Palermo to Brindisi:
- Sais Autolinee
- Assistance
- Priority boarding
- Accessible seating.
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Palermo to Brindisi depends on the bus companies:
- Sais Autolinee
- You can cancel your ticket up to 24 hours before departure for a partial refund. No refunds for cancellations within 24 hours.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus, Sais Autolinee, Infobus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Palermo to Brindisi.
Yes, the following luggage options are included when booking a bus ticket from Palermo to Brindisi:
- Sais Autolinee
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Palermo to Brindisi:
- Sais Autolinee
- Additional luggage can be purchased for a fee.
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Palermo to Brindisi. The following conditions apply:
- Sais Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Palermo to Brindisi with the following bus company: FlixBus, Sais Autolinee, Infobus
Yes, there are USB plugs on board the bus from Palermo to Brindisi with the following bus company: FlixBus, Sais Autolinee, Infobus.
Yes, there is Wifi on board the bus from Palermo to Brindisi with the following bus company: FlixBus, Sais Autolinee, Infobus.
Since both Palermo and Brindisi are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Palermo to Brindisi among Omio's users.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Brindisi, travelers should be cautious of pickpocketing, especially in crowded areas like the port and public transport hubs. Common scams include overpriced taxi rides and unlicensed tour operators. It's advisable to use official transportation services and remain vigilant with personal belongings in busy spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Palermo to Brindisi
Palermo
Brindisi
Most popular bus connections from Palermo
More options for your journey from Palermo to Brindisi
Here are some other resources that might have the information you need
Most popular buses to and from Brindisi and Palermo
Most popular bus connections to Brindisi
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