- Must visit
Pinacoteca di Brera
Milan’s premier fine-art gallery, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
Cheapest price
$143
Average price
$166
Fastest journey
22 h 20 m
Average duration
23 h 4 m
Buses per day
6
Distance
887 km
The best way to find a cheap bus ticket from Palermo to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Milan will cost around $166 if you buy it on the day, but the cheapest tickets can be found for only $143.
Of the 6 buses that leave Palermo for Milan on Sun, Jul 12, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Jul 12 the direct buses cover the 887 km distance in an average of 23 h 4 m but if you time it right, some buses will get you there in just 22 h 20 m .
On Sun, Jul 12 the slowest buses will take 23 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Palermo to Milan among Omio's users. If you are prioritising price take the ferry with prices starting from $77. For those with little time consider booking a flight which can get you there in 2h 3m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.8kg. The ticket price range depends on the travel mode: a ferry costs an average of $77, and a train costs an average of $87.
Distance: 551 miles (887 km)
| Bus | Most popular Flight | Train | Ferry | Driving |
|---|---|---|---|---|
$129 Average price | $131 Average price | $172 Average price | $87 Average price Cheapest | $129 Average price (fuel + tolls) |
19h 47m Average total duration 19h 17m Onboard + 30m Additional time* | 5h 3m Average total duration Fastest 2h 3m Onboard + 3h 0m Additional time* | 15h 45m Average total duration 15h 15m Onboard + 30m Additional time* | 21h 10m Average total duration 20h 10m Onboard + 1h 0m Additional time* | 25h 7m Average total duration (door-to-door) |
0.9 - 2.2kg CO2 emissions | - CO2 emissions | 0.3 - 0.8kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | ![]() Most popular ferry company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Palermo to Milan:
A ferry is $42 (€35) less than a bus for this route with tickets for a bus from Palermo to Milan costing on average $129 (€106).
A ferry is $44 (€36) less than a flight for this route with tickets for a flight from Palermo to Milan costing on average $131 (€108).
A ferry is $85 (€70) less than a train for this route with tickets for a train from Palermo to Milan costing on average $172 (€142).
Other travel options to Milan take longer:
Train takes on average 15h 15m.
Bus takes on average 19h 17m.
Ferry takes on average 20h 10m.
You'll arrive about 5h 50m sooner (19h 17m by bus vs 25h 7m by car). Tickets start at around $129 (€106) compared to roughly $129 (€106) in fuel and tolls — a bit more, but you're getting time back, skipping traffic and parking, and you can work or rest on board.
Direct coaches are operated by Itabus, FlixBus, BlaBlaCar, Autoservizi Salemi Srl.
Driving makes more sense if you're travelling as a group (where fuel splits across several people), want flexibility on timing, or plan to stop en route.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 09:10AM | Arrival Time 07:50AM | Duration 22h40 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $119 |
Operator FlixBus | Departure Time 03:25PM | Arrival Time 02:35PM | Duration 23h10 | Departure days Everyday | Cheapest price $123 |
Operator Salemi | Departure Time 06:00PM | Arrival Time 01:10PM | Duration 19h10 | Departure days Mon, Wed, Sat | Cheapest price $107 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 08:55PM | Duration 23h45 | Departure days Everyday | Cheapest price $104 |
The table below shows live departures for Palermo to Milan buses for today, Saturday, July 11. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 9:10 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 23h25 | 8:35 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 9:10 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 22h40 | 7:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus | 3:25 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 22h20 | 1:45 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 3:25 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 23h10 | 2:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
S202 · 700 | 6:00 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 19h10 | 1:10 PM Milano, San Donato M3 | 1 transfer | |
S202 · 700 | 6:00 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 19h50 | 1:50 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 9:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 23h45 | 8:55 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus · FlixBus | 9:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 24h30 | 9:40 PM Milano, Autostazione Lampugnano | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Palermo to Milan run on average 6 times per day, taking around 19h 17m. Cheap bus tickets for this journey start at $72 (€59) but you can travel from only $23 (€19) by flight.
There are 1 buses per day. The earliest bus runs at 01:01, the last at 23:05. The fastest bus covers the 551 miles (887 km) distance in 19h 10m.
Distance 551 miles (887 km) |
Average bus duration 19h 17m |
Cheapest ticket price $72 (€59) |
Buses per day 6 |
Direct buses 1 |
Fastest bus 19h 10m |
First bus 1:01 AM |
Last bus 11:05 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 49 days |
Discover the best of Milan — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Milan trip today.
Milan’s premier fine-art gallery, known for masterpieces by Raphael, Caravaggio, and Mantegna in the historic Brera district.
A leading museum of 20th-century Italian art facing Piazza del Duomo, with strong Futurist and modern collections.
A major design-forward museum for world cultures and blockbuster temporary exhibitions in the Tortona area.
Milan’s canal district, loved for waterside walks, lively atmosphere, and photogenic bridges and alleys.
A charming central neighborhood with elegant streets, galleries, boutiques, and a classic Milan atmosphere.
Milan’s main square and symbolic heart, framed by the cathedral, museums, and major historic buildings.
Creamy saffron risotto, one of Milan’s signature dishes, prized for its rich color and elegant flavor.
Braised veal shank, often served with risotto alla Milanese, a classic celebratory dish from Milanese cuisine.
Breaded veal cutlet fried until golden, a famous Milan specialty often compared with schnitzel but traditionally thicker.
Legendary casual stop near the Duomo, famous for panzerotti and a beloved institution for quick, affordable bites.
Well-known modern Milanese restaurant near Porta Nuova, celebrated for refined local classics in a stylish setting.
Historic trattoria serving traditional Milanese and Lombard dishes in an old-fashioned, atmospheric dining room.
Prices are high by Italian standards, especially for hotels and central dining, though transit and casual food stay manageable.
Tipping is modest. Service may be included. Round up or leave EUR 1-2 for coffee, 5-10% at restaurants for good service, and round up taxi fares.
Official public transport app
Orio al Serio Milan Bergamo Airport Bus Station, Bergamo -> Milano Centrale, Milan
Find answers to the most common questions about traveling from Palermo to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

Most Palermo to Milan buses use the Palermo, Via Tommaso Fazello (Terminal Bus) to Milano, Autostazione Lampugnano station pair, with some services arriving at Milano, San Donato - Settore B (Viale Giuseppe Impastato). Use this guide to compare Palermo and Milan bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Milano, Autostazione Lampugnano is 5 km from Milan city centre. Public transport options include:
Milano, Autostazione Lampugnano has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Lampugnano (in the station), Trattoria Milano (0.5 km), Pizza Express (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Milano, Autostazione Lampugnano.
Available at Milano, Autostazione Lampugnano: Parking, Taxis, WC.
Accessibility facilities are available at Milano, Autostazione Lampugnano: Elevators, ramps.
Milano, San Donato - Settore B (Viale Giuseppe Impastato) is 6 km from Milan city centre. Public transport options include:
Milano, San Donato - Settore B (Viale Giuseppe Impastato) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafeteria Italiana (in the station), Fast Food Express (in the station), Trattoria Milano (0.5 km).
Free Wi-Fi. ATMs are located near the main entrance for cash withdrawals.
Ticket office support is available at Milano, San Donato - Settore B (Viale Giuseppe Impastato).
Available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Parking, Taxis, WC.
Accessibility facilities are available at Milano, San Donato - Settore B (Viale Giuseppe Impastato): Elevators, ramps.
Here are some other resources that might have the information you need