- Must visit
Museo Archeologico Provinciale Francesco Ribezzo
Main civic museum with archaeology, sculptures, and local history collections that provide the best introduction to Brindisi and its territory.
Cheapest price on Sep 18
€32
Average ticket price on Sep 18
€46
Fastest journey on Sep 18
13 h 5 m
Average journey duration on Sep 18
14 h 35 m
Buses on Sep 18
8
Distance
710 km
The best way to find a cheap bus ticket from Pisa to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Brindisi will cost around €46 if you buy it on the day, but the cheapest tickets can be found for only €32.
On Fri, Sep 18, we found 8 buses from Pisa to Brindisi, including 1 direct services.
On Fri, Sep 18 the direct buses cover the 710 km distance in an average of 14 h 35 m but if you time it right, some buses will get you there in just 13 h 5 m .
On Fri, Sep 18 the slowest buses will take 16 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
207
131 · 108
FlixBus · FlixBus
207
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Pisa to Brindisi among Omio's users. If you are prioritising price, take the train, with an average ticket price of €60 For those with little time, consider booking a flight, which has an average total journey time of 4h 56m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.6kg. Average ticket prices depend on the travel mode: a train costs an average of €60, while a flight costs an average of €311.
Distance: 441 miles (710 km)
| Bus | Most popular Flight | Train |
|---|---|---|
€82 Average price | €311 Average price | €60 Average price Cheapest |
13h 34m Average total duration 13h 4m Onboard + 30m Additional time* | 4h 56m Average total duration Fastest 2h 56m Onboard + 2h 0m Additional time* | 10h 33m Average total duration 10h 3m Onboard + 30m Additional time* |
0.7 - 1.8kg CO2 emissions | - CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Pisa to Brindisi:
A train is €22 less than a bus for this route with tickets for a bus from Pisa to Brindisi costing on average €82.
A train is €251 less than a flight for this route with tickets for a flight from Pisa to Brindisi costing on average €311.
Other travel options to Brindisi take longer:
Train takes on average 10h 3m.
Bus takes on average 13h 4m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:25AM | Arrival Time 04:40PM | Duration 16h15 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price €33 |
Operator FlixBus | Departure Time 04:45AM | Arrival Time 10:25PM | Duration 17h40 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price €24 |
Operator FlixBus | Departure Time 06:05AM | Arrival Time 10:25PM | Duration 16h20 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price €25 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 06:10AM | Duration 22h55 | Departure days Wed | Cheapest price €57 |
Operator Marino Autolinee | Departure Time 08:20AM | Arrival Time 10:10PM | Duration 13h50 | Departure days Everyday | Cheapest price €42 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 06:10AM | Duration 18h10 | Departure days Thu | Cheapest price €67 |
Operator FlixBus | Departure Time 01:25PM | Arrival Time 06:10AM | Duration 16h45 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price €29 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 10:05AM | Duration 16h55 | Departure days Tue, Wed | Cheapest price €28 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 07:15AM | Duration 13h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €37 |
Operator Marino Autolinee | Departure Time 07:20PM | Arrival Time 08:25AM | Duration 13h05 | Departure days Everyday | Cheapest price €43 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 01:55PM | Duration 15h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €43 |
The table below shows live departures for Pisa to Brindisi buses for tomorrow, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 12:25 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 16h15 | 4:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 4:45 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 17h40 | 10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 6:05 AM Pisa (Pisamover via San Giusto/Aurelia) | 16h20 | 10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
207 | 8:20 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h50 | 10:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
FlixBus · FlixBus | 1:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 16h45 | 6:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 5:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h50 | 7:15 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
131 · 108 | 7:20 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h05 | 8:25 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 15h55 | 1:55 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Pisa to Brindisi run on average 6 times per day, taking around 13h 4m. Cheap bus tickets for this journey start at €30 but you can travel from only €9 by train.
There are 1 buses per day. The earliest bus runs at 00:25, the last at 23:30. The fastest bus covers the 441 miles (710 km) distance in 11h 50m.
Distance 441 miles (710 km) |
Average bus duration 13h 4m |
Cheapest ticket price €30 |
Buses per day 6 |
Direct buses 1 |
Fastest bus 11h 50m |
First bus 12:25 AM |
Last bus 11:30 PM |
Cheapest Month Feb |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 35 days |
Discover the best of Brindisi — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brindisi trip today.
Main civic museum with archaeology, sculptures, and local history collections that provide the best introduction to Brindisi and its territory.
Archaeological zone and small interpretive museum preserving a Roman domus with mosaics, ideal for understanding everyday life in ancient Brindisi.
Historic site museum in a circular medieval church, appreciated for architecture and exhibits linked to pilgrims, crusaders, and the city’s past.
Brindisi’s main waterfront promenade, ideal for harbor views, evening walks, and seeing the city’s maritime life at its most atmospheric.
Historic square beside the cathedral, Roman column, and staircase, making it one of the most important and scenic urban spaces in Brindisi.
Elegant central square framed by historic buildings and cafés nearby, a practical base for sightseeing and people-watching in the old town.
Rustico leccese is a flaky pastry filled with béchamel, tomato, and mozzarella. Popular across Salento, it is a beloved snack in Brindisi bars and bakeries.
Puccia salentina is a round Apulian bread sandwich, often stuffed with tuna, olives, capers, or vegetables. It is a classic street food in Brindisi and nearby Salento.
Fave e cicorie pairs creamy pureed fava beans with wild chicory. This humble Puglian staple is deeply traditional and widely eaten in Brindisi homes and trattorias.
Refined seafood restaurant in central Brindisi, known for elegant tasting menus, polished service, and creative Apulian cuisine in a stylish setting.
Well-known traditional restaurant serving Apulian seafood and local classics. Relaxed, reliable, and popular for fresh fish near the historic center.
Casual seafood spot appreciated for raw and cooked fish dishes, simple local preparations, and an unfussy atmosphere close to the waterfront.
Moderate for Italy. Hotels and dining are usually cheaper than Rome or Milan, while local buses and casual meals stay fairly affordable for tourists.
Service is often included or modest. Round up or leave €1-2 at cafes, 5-10% at restaurants for good service, and round up taxi fares.
Official public transport app
Via Giuseppe Maria Galanti, Brindisi -> Brindisi Railway Station, Brindisi
Find answers to the most common questions about traveling from Pisa to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

Most Pisa to Brindisi buses use the Pisa, Via delle Fiamme Gialle (Park Pietrasantina) to Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) station pair. Use this guide to compare Pisa and Brindisi bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) is 1 km from Pisa city centre. Public transport options include:
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, Ticket Office, Bike Parking, and Bike Rental.
Wi-Fi is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina). ATMs are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Ticket office support is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Parking, Taxis, WC.
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): The station is accessible for people with reduced mobility.
Pisa (Pisamover via San Giusto/Aurelia) is 1 km from Pisa city centre. Public transport options include:
Pisa (Pisamover via San Giusto/Aurelia) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Pisa (Pisamover via San Giusto/Aurelia). ATMs are available at Pisa (Pisamover via San Giusto/Aurelia).
Ticket office support is available at Pisa (Pisamover via San Giusto/Aurelia).
Available at Pisa (Pisamover via San Giusto/Aurelia): Parking, Taxis, WC.
Accessibility facilities are available at Pisa (Pisamover via San Giusto/Aurelia): Wheelchair accessible with assistance.
Here are some other resources that might have the information you need