- Recommended
Museo Archeologico Provinciale Francesco Ribezzo
The city’s main archaeological museum, with finds from ancient Brundisium and the wider Salento area, including Roman and underwater archaeology.
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The cheapest and fastest buses from Pisa to Brindisi
Showing times and prices for Jun 20
Cheapest price
$74
Average price
$122
Fastest journey
13 h 5 m
Average duration
14 h 36 m
Buses per day
7
Distance
710 km
Cheap tickets
The best way to find a cheap bus ticket from Pisa to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Brindisi will cost around $122 if you buy it on the day, but the cheapest tickets can be found for only $74.
Fast buses
Of the 7 buses that leave Pisa for Brindisi on Sat, Jun 20, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct buses cover the 710 km distance in an average of 14 h 36 m but if you time it right, some buses will get you there in just 13 h 5 m .
On Sat, Jun 20 the slowest buses will take 16 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
131 · 1087:20 PM13h05Pisa, Via delle Fiamme Gialle (Park Pietrasantina)8:25 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$741One-way1 transfer- 2078:20 AM13h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:10 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$1131One-way0 transfers
FlixBus · FlixBus5:25 PM13h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)7:15 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$1151One-way1 transfer- FlixBus · FlixBus1:25 PM16h45Pisa, Via delle Fiamme Gialle (Park Pietrasantina)6:10 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$1161One-way1 transfer
- FlixBus · FlixBus10:00 PM15h55Pisa, Via delle Fiamme Gialle (Park Pietrasantina)1:55 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$1291One-way1 transfer
- 131 · 1087:20 PM13h05Pisa, Via delle Fiamme Gialle (Park Pietrasantina)8:25 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$741One-way1 transfer
- 2078:20 AM13h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:10 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$1131One-way0 transfers
- FlixBus · FlixBus5:25 PM13h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)7:15 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$1151One-way1 transfer
- FlixBus · FlixBus10:00 PM15h55Pisa, Via delle Fiamme Gialle (Park Pietrasantina)1:55 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$1291One-way1 transfer
- FlixBus · FlixBus · FlixBus6:05 AM16h20Pisa, Aeroporto Parcheggio Aurelia10:25 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)$1691One-way2 transfers
Travel Information
Compare train, bus, and flight for Pisa to Brindisi
Omio recommends booking the flight as it is the most popular option from Pisa to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from $34. For those with little time consider booking a flight which can get you there in 1h 28m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $34, and a flight costs an average of $21.
Distance: 441 miles (710 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$65 Average price Cheapest | $123 Average price | $89 Average price |
14h 7m Average total duration 13h 37m Onboard + 30m Additional time* | 4h 28m Average total duration Fastest 1h 28m Onboard + 3h 0m Additional time* | 10h 3m Average total duration 9h 33m Onboard + 30m Additional time* |
0.7 - 1.8kg CO2 emissions | - CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
Most popular bus company |  Most popular airline |  Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Pisa to Brindisi is a bus with an average price of $65 (€53).
This is compared to other travel options from Pisa to Brindisi:
A bus is $24 (€20) less than a train for this route with tickets for a train from Pisa to Brindisi costing on average $89 (€73).
A bus is $58 (€48) less than a flight for this route with tickets for a flight from Pisa to Brindisi costing on average $123 (€101).
The fastest way to travel from Pisa to Brindisi is by flight with an average journey time of 1h 28m.
Other travel options to Brindisi take longer:
Train takes on average 9h 33m.
Bus takes on average 13h 37m.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Brindisi including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Pisa to Brindisi among Omio's users.
Pisa to Brindisi Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:25AM | Arrival Time 04:30PM | Duration 16h05 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $93 |
Operator FlixBus | Departure Time 04:45AM | Arrival Time 10:25PM | Duration 17h40 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $96 |
Operator FlixBus | Departure Time 06:05AM | Arrival Time 10:25PM | Duration 16h20 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $138 |
Operator Marino Autolinee | Departure Time 08:20AM | Arrival Time 10:10PM | Duration 13h50 | Departure days Everyday | Cheapest price $83 |
Operator FlixBus | Departure Time 09:40AM | Arrival Time 06:10AM | Duration 20h30 | Departure days Wed | Cheapest price $96 |
Operator FlixBus | Departure Time 01:25PM | Arrival Time 06:10AM | Duration 16h45 | Departure days Mon, Tue, Fri, Sat | Cheapest price $95 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 10:05AM | Duration 16h55 | Departure days Tue, Wed | Cheapest price $89 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 07:15AM | Duration 13h50 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $94 |
Operator Marino Autolinee | Departure Time 07:20PM | Arrival Time 08:25AM | Duration 13h05 | Departure days Everyday | Cheapest price $67 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 01:55PM | Duration 15h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $98 |
Live departures
Pisa to Brindisi bus times
The table below shows live departures for Pisa to Brindisi buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 1:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 16h45 | 6:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
| FlixBus · FlixBus | 5:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h50 | 7:15 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
| 131 · 108 | 7:20 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h05 | 8:25 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
| FlixBus · FlixBus | 10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 15h55 | 1:55 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
| Saturday, June 20 | |||||
| FlixBus · FlixBus | 4:45 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 17h40 | 10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
| FlixBus · FlixBus · FlixBus | 6:05 AM Pisa, Aeroporto Parcheggio Aurelia | 16h20 | 10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
| 207 | 8:20 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h50 | 10:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Brindisi by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Pisa to Brindisi buses with Omio?
Marino Autolinee as well as FlixBus offer buses services from Pisa to Brindisi.
Omio is an official ticket reseller for all your travel options from Pisa to Brindisi.
Why book with Omio vs Marino Autolinee?
- Compare with other providers: On Omio, you can not only buy tickets for Marino Autolinee, but also compare tickets for the likes of FlixBus to find the best option for your trip from Pisa to Brindisi.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Marino Autolinee with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Brindisi.
Why book with Omio over Checkmybus, Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Pisa to Brindisi.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Brindisi.
Journey information
Overview: Bus from Pisa to Brindisi
ItalyItaly
Buses from Pisa to Brindisi run on average 6 times per day, taking around 13h 37m. Cheap bus tickets for this journey start at $34 (€28) but you can travel from only $21 (€17) by flight.
There are 1 buses per day. The earliest bus runs at 00:25, the last at 23:30. The fastest bus covers the 441 miles (710 km) distance in 13h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $21 (€17)
Distance 441 miles (710 km) |
Average bus duration 13h 37m |
Cheapest ticket price $34 (€28) |
Buses per day 6 |
Direct buses 1 |
Fastest bus 13h 5m |
First bus 12:25 AM |
Last bus 11:30 PM |
Cheapest Month Feb |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 1 day |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $21 (€17)
Bus providers: Marino Autolinee, FlixBus from Pisa to BrindisiYou can travel by bus between Pisa to Brindisi with Marino Autolinee, FlixBus for as low as $21 (€17). When you search for schedules and tickets, Omio will show you the best journey
Marino Autolinee
About
MarinoBus is an Italian bus company with more than 200 destinations and 6,000 connections across Italy and Europe. Originally focused on Basilicata and Apulia, its network has expanded to cover the rest of Italy as well as Switzerland, France, Germany, and Luxembourg. All MarinoBus coaches are equipped with spacious reclining seats, air conditioning, onboard restrooms, WiFi, minibars, and color TVs. For your next trip, you can book the standard ticket, which includes one piece of hand luggage and up to two checked bags per passenger
Luggage & cancellation policy
Average Duration
13h 5m
Cheapest Price
$54 (€44)
Luggage included
One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
10€ per additional bag up to 20 kg.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
13h 50m
Cheapest Price
$34 (€28)
FlixBus frequency
4 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Brindisi
Things to do in Brindisi
Discover the best of Brindisi — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brindisi trip today.
Palazzo Granafei Nervegna
A historic palace used for exhibitions and cultural displays, also known for preserved Roman remains in its underground area.
Museo Diocesano Giovanni Tarantini
Diocesan museum with sacred art, liturgical objects, paintings, and items linked to the religious history of Brindisi.
- Must visit
Lungomare Regina Margherita
Brindisi’s best-known waterfront promenade, ideal for harbor views, evening walks, and seeing the city’s maritime character.
- Recommended
Piazza Duomo
Atmospheric square around the cathedral, distinct from many Italian piazzas for its quiet, enclosed monumental setting.
- Recommended
Scalinata Virgilio
Waterside staircase near the Roman Columns, a favorite photo spot and one of the city’s most recognizable viewpoints.
- Vegetarian
- Vegan
Orecchiette Alle Cime Di Rapa
Handmade ear-shaped pasta with turnip greens, garlic, olive oil, and often chili. A classic Pugliese dish closely associated with everyday cooking in the region.
- Vegetarian
- Vegan
- Gluten-free
Fave E Cicorie
A rustic Puglian staple of pureed dried broad beans served with wild chicory. It is simple, traditional peasant food and one of the area’s most emblematic dishes.
Tiella Di Riso, Patate E Cozze
A baked layered dish of rice, potatoes, and mussels with tomato, onion, and breadcrumbs. Popular across coastal Puglia and especially loved for family meals.
Betty - Cibo E Vino In Centro
Well-regarded central restaurant known for polished Puglian cooking, seafood, and a refined but relaxed atmosphere near the historic center.
Spilusi
Popular casual venue in Brindisi for creative sandwiches, puccia, and quick local bites, with a lively informal atmosphere.
La Locanda Del Porto
Established harbor-side dining spot focused on seafood and regional dishes, appreciated for its setting and classic local menu.
Euro
Generally moderate by Italian standards. Dining and coffee are reasonable, while hotels cost more in peak summer.
Average meal costs
- Budget
- EUR 8-15 for pizza, panini, or a simple lunch.
- Mid-range
- EUR 20-35 per person for a casual restaurant meal.
- Fine dining
- EUR 50-90 per person at upscale seafood or tasting-menu spots.
- Coffee
- EUR 1.20-2.50 for espresso or cappuccino.
Tipping culture
Service is often included or modest. Locals may round up or leave EUR 1-2 at cafes, 5-10% at restaurants for good service, and round up taxi fares.
STP Brindisi
Get the appOfficial public transport app
Prices
- Single ticket
- EUR 1.00
- Day pass
- None
To the city center
Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale), Brindisi -> Brindisi Railway Station, Brindisi
- Distance
- 2 km
- Travel time
- 10 min
- Buy tickets before boarding when possible, as onboard sales may be limited depending on the route and operator.
- Check STP Brindisi timetables in advance because frequencies can be lower in the evening and on holidays.
FAQs: Bus from Pisa to Brindisi
Find answers to the most common questions about traveling from Pisa to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Pisa to Brindisi can start from as little as $34 (€28) when you book in advance. The average bus ticket price for Pisa to Brindisi is $65 (€53) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Pisa to Brindisi is 13h 5m to travel the 441 miles (710 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Pisa to Brindisi leaves at 12:25 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Pisa to Brindisi leaves at 11:30 PM.
Yes, there are 1 direct buses a day from Pisa to Brindisi with . Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Pisa to Brindisi, you can count on Marino Autolinee, FlixBus for the best way to get you to Brindisi. You can also check all possible bus companies who offer a service between Pisa and Brindisi and compare the amenities they offer before buying a bus ticket.
When departing from Pisa , you have various bus station options to start your journey from including Pisa, Via delle Fiamme Gialle (Park Pietrasantina), Pisa, Aeroporto Parcheggio Aurelia, Livorno, Piazza Dante (Stazione ferroviaria), Pisa, Lucca, Stazione FS, Lucca, Viale Regina Margherita / Via Montanara, Lucca . When arriving in Brindisi , you can end your journey in bus stations like Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale), Brindisi .Passengers board the bus most frequently from Pisa, Via delle Fiamme Gialle (Park Pietrasantina), which is located around away from the city centre, and they get off the bus at Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale), located 0 away from the city centre.
A trip to Brindisi from Pisa is worth doing but not as a day trip with a journey time of 13h 5m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Pisa to Brindisi is February.
It's helpful to compare your options as there are 3 ways to travel between Pisa and Brindisi including taking a train, bus, and flight.
Yes, there are bathrooms on board the bus from Pisa to Brindisi for bus company Marino Autolinee, FlixBus.
Yes, the following accessibility options are available when taking the bus from Pisa to Brindisi:
- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Whether you can cancel your bus ticket from Pisa to Brindisi depends on the bus companies:
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Marino Autolinee, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Pisa to Brindisi.
Yes, the following luggage options are included when booking a bus ticket from Pisa to Brindisi:
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Pisa to Brindisi:
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Pisa to Brindisi. The following conditions apply:
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Pisa to Brindisi with the following bus company: Marino Autolinee, FlixBus
Yes, there are USB plugs on board the bus from Pisa to Brindisi with the following bus company: Marino Autolinee, FlixBus.
Yes, there is Wifi on board the bus from Pisa to Brindisi with the following bus company: Marino Autolinee, FlixBus.
Since both Pisa and Brindisi are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Pisa to Brindisi among Omio's users.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Brindisi, travelers should be cautious of pickpocketing, especially in crowded areas like the port and public transport hubs. Common scams include overpriced taxi rides and unlicensed tour operators. It's advisable to use official transportation services and remain vigilant with personal belongings in busy spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Pisa to Brindisi
Pisa
Brindisi
The major bus station for departures in Pisa is Pisa, Via delle Fiamme Gialle (Park Pietrasantina). Find all the information you need to know about services, amenities and connections at Pisa, Via delle Fiamme Gialle (Park Pietrasantina) for your trip from Pisa to Brindisi.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina)
information
Pisa, Aeroporto Parcheggio Aurelia
information
Pisa
information
The major bus station for arrivals in Brindisi is Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale). Find all the information you need to know about services, amenities and connections at Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) for your trip to Brindisi from Pisa.
Brindisi
information
Most popular bus connections from Pisa
More options for your journey from Pisa to Brindisi
Here are some other resources that might have the information you need
Most popular buses to and from Brindisi and Pisa
Most popular bus connections to Brindisi
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