The cheapest and fastest buses from Pisa to Brindisi
Cheapest price
$85
Average price
$113
Fastest journey
13 h
Average duration
13 h 30 m
Buses per day
3
Distance
710 km
The best way to find a cheap bus ticket from Pisa to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Brindisi will cost around $113 if you buy it on the day, but the cheapest tickets can be found for only $85.
Of the 3 buses that leave Pisa for Brindisi on Sun, Dec 21, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Dec 21 the direct buses cover the 710 km distance in an average of 13 h 30 m but if you time it right, some buses will get you there in just 13 h .
On Sun, Dec 21 the slowest buses will take 13 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Travel Information
Compare train, bus, and flight for Pisa to Brindisi
Omio recommends booking the flight as it is the most popular option from Pisa to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from €47. For those with little time consider booking a flight which can get you there in 1h 27m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €47, and a flight costs an average of €28.
Distance: 441 miles (710 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€69 Average price Cheapest | €154 Average price | €78 Average price |
14h 28m Average total duration 13h 58m Onboard + 30m Additional time* | 4h 27m Average total duration Fastest 1h 27m Onboard + 3h 0m Additional time* | 9h 30m Average total duration 9h 0m Onboard + 30m Additional time* |
0.7 - 1.8kg CO2 emissions | - CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Pisa to Brindisi Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:25AM | Arrival Time 04:45PM | Duration 16h20 | Departure days Tue, Fri, Sat | Cheapest price $127 |
Operator BlaBlaCar | Departure Time 04:50AM | Arrival Time 03:00PM | Duration 10h10 | Departure days Sat | Cheapest price $62 |
Operator FlixBus | Departure Time 05:45AM | Arrival Time 09:40PM | Duration 15h55 | Departure days Tue, Sat | Cheapest price $167 |
Operator FlixBus | Departure Time 06:00AM | Arrival Time 09:40PM | Duration 15h40 | Departure days Tue, Sat | Cheapest price $167 |
Operator BlaBlaCar | Departure Time 09:00AM | Arrival Time 07:00PM | Duration 10h00 | Departure days Fri | Cheapest price $78 |
Operator BlaBlaCar | Departure Time 12:00PM | Arrival Time 10:20PM | Duration 10h20 | Departure days Sat | Cheapest price $59 |
Operator FlixBus | Departure Time 01:25PM | Arrival Time 06:10AM | Duration 16h45 | Departure days Tue, Fri, Sat | Cheapest price $119 |
Operator FlixBus | Departure Time 04:45PM | Arrival Time 10:30AM | Duration 17h45 | Departure days Fri | Cheapest price $130 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 07:15AM | Duration 13h50 | Departure days Sat | Cheapest price $168 |
Operator Marino Autolinee | Departure Time 07:25PM | Arrival Time 08:25AM | Duration 13h00 | Departure days Tue, Sat | Cheapest price $145 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 01:25PM | Duration 15h25 | Departure days Tue, Sat | Cheapest price $160 |
Live departures
Pisa to Brindisi bus times
The table below shows live departures for Pisa to Brindisi buses for today, Saturday, December 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 12:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 16h45 | 5:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 4:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h50 | 6:15 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
104 · 108 | 6:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h00 | 7:25 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 9:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 15h25 | 12:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
| Sunday, December 21 | |||||
![]() | 6:30 AM Pisa | 13h40 | 8:10 PM Brindisi | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Pisa to Brindisi by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 21
Dec 22
Dec 23
Dec 24
Dec 25
Dec 26
Dec 27
Dec 28
Dec 29
Dec 30
Dec 31
Jan 01
Jan 02
Jan 03
Jan 04
Jan 05
Jan 06
Jan 07
Jan 08
Jan 09
Jan 10
Journey information
Overview: Bus from Pisa to Brindisi
Buses from Pisa to Brindisi run on average 6 times per day, taking around 13h 58m. Cheap bus tickets for this journey start at $59 (€47) but you can travel from only $35 (€28) by flight.
There are 1 buses per day. The earliest bus runs at 00:25, the last at 23:30. The fastest bus covers the 441 miles (710 km) distance in 13h 0m.
Distance 441 miles (710 km) |
Average bus duration 13h 58m |
Cheapest ticket price $59 (€47) |
Buses per day 6 |
Direct buses 1 |
Fastest bus 13h 0m |
First bus 00:25 |
Last bus 23:30 |
Bus providers: Marino Autolinee, FlixBus from Pisa to BrindisiYou can travel by bus between Pisa to Brindisi with Marino Autolinee, FlixBus for as low as $35 (€28). When you search for schedules and tickets, Omio will show you the best journey
Marino Autolinee
FlixBus
FAQs: Bus from Pisa to Brindisi
Find answers to the most common questions about traveling from Pisa to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

Passengers board the bus most frequently from Pisa, Via delle Fiamme Gialle (Park Pietrasantina), which is located around 1.9 miles (3 km) away from the city centre, and they get off the bus at Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale), located 0.6 miles (1 km) away from the city centre.
- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Pisa to Brindisi, follow these tips:
Start your search now and compare ticket prices to find the best deal!
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Marino Autolinee
- Small pets allowed in carriers
- Larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
popular bus stations
Popular bus stations from Pisa to Brindisi
Most popular bus connections from Pisa
More options for your journey from Pisa to Brindisi
Here are some other resources that might have the information you need


