- Must visit
Museo Archeologico Provinciale Francesco Ribezzo
Main civic museum with archaeology, sculptures, and local history collections that provide the best introduction to Brindisi and its territory.
The best way to find a cheap bus ticket from Pisa to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Brindisi will cost around €51 if you buy it on the day, but the cheapest tickets can be found for only €43.
On Mon, Nov 02, we found 7 buses from Pisa to Brindisi, including 1 direct services.
On Mon, Nov 02 the direct buses cover the 710 km distance in an average of 14 h 35 m but if you time it right, some buses will get you there in just 13 h 5 m .
On Mon, Nov 02 the slowest buses will take 16 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
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131 · 108
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Buses from Pisa to Brindisi run on average 7 times per day, taking around 13h 7m. Cheap bus tickets for this journey start at €25 but you can travel from only €10 by train.
There are 1 buses per day. The earliest bus runs at 00:25, the last at 23:30. The fastest bus covers the 441 miles (710 km) distance in 11h 50m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Pisa to Brindisi.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:25AM | Arrival Time 04:40PM | Duration 16h15 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price €44 |
Operator FlixBus | Departure Time 04:45AM | Arrival Time 10:25PM | Duration 17h40 | Departure days Fri, Sun | Cheapest price €70 |
Operator FlixBus | Departure Time 06:05AM | Arrival Time 10:25PM | Duration 16h20 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price €36 |
Operator FlixBus | Departure Time 07:15AM | Arrival Time 06:10AM | Duration 22h55 | Departure days Tue, Wed | Cheapest price €51 |
Operator Marino Autolinee | Departure Time 08:20AM | Arrival Time 10:10PM | Duration 13h50 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price €45 |
Operator FlixBus | Departure Time 12:00PM | Arrival Time 06:10AM | Duration 18h10 | Departure days Thu | Cheapest price €64 |
Operator FlixBus | Departure Time 01:25PM | Arrival Time 06:10AM | Duration 16h45 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price €41 |
Operator BlaBlaCar | Departure Time 02:00PM | Arrival Time 01:20AM | Duration 11h20 | Departure days Wed | Cheapest price €74 |
Operator FlixBus | Departure Time 05:10PM | Arrival Time 07:15AM | Duration 14h05 | Departure days Tue, Wed, Sun | Cheapest price €49 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 07:15AM | Duration 13h50 | Departure days Mon, Thu, Fri, Sat | Cheapest price €36 |
Operator Marino Autolinee | Departure Time 07:20PM | Arrival Time 08:25AM | Duration 13h05 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price €40 |
Operator FlixBus | Departure Time 10:00PM | Arrival Time 01:55PM | Duration 15h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €40 |
The table below shows live departures for Pisa to Brindisi buses for tomorrow, Monday, November 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 12:25 AM Pisa (Pisamover via San Giusto/Aurelia) | 16h15 | 4:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 6:05 AM Pisa (Pisamover via San Giusto/Aurelia) | 16h20 | 10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
207 | 8:20 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h50 | 10:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
FlixBus · FlixBus | 1:25 PM Pisa (Pisamover via San Giusto/Aurelia) | 16h45 | 6:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 5:25 PM Pisa (Pisamover via San Giusto/Aurelia) | 13h50 | 7:15 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
131 · 108 | 7:20 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h05 | 8:25 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 10:00 PM Pisa (Pisamover via San Giusto/Aurelia) | 15h55 | 1:55 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Buses from Pisa to Brindisi with FlixBus and Marino Autolinee. Overnight buses available on this route with FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Brindisi — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brindisi trip today.
Main civic museum with archaeology, sculptures, and local history collections that provide the best introduction to Brindisi and its territory.
Archaeological zone and small interpretive museum preserving a Roman domus with mosaics, ideal for understanding everyday life in ancient Brindisi.
Historic site museum in a circular medieval church, appreciated for architecture and exhibits linked to pilgrims, crusaders, and the city’s past.
Brindisi’s main waterfront promenade, ideal for harbor views, evening walks, and seeing the city’s maritime life at its most atmospheric.
Historic square beside the cathedral, Roman column, and staircase, making it one of the most important and scenic urban spaces in Brindisi.
Elegant central square framed by historic buildings and cafés nearby, a practical base for sightseeing and people-watching in the old town.
Rustico leccese is a flaky pastry filled with béchamel, tomato, and mozzarella. Popular across Salento, it is a beloved snack in Brindisi bars and bakeries.
Puccia salentina is a round Apulian bread sandwich, often stuffed with tuna, olives, capers, or vegetables. It is a classic street food in Brindisi and nearby Salento.
Fave e cicorie pairs creamy pureed fava beans with wild chicory. This humble Puglian staple is deeply traditional and widely eaten in Brindisi homes and trattorias.
Refined seafood restaurant in central Brindisi, known for elegant tasting menus, polished service, and creative Apulian cuisine in a stylish setting.
Well-known traditional restaurant serving Apulian seafood and local classics. Relaxed, reliable, and popular for fresh fish near the historic center.
Casual seafood spot appreciated for raw and cooked fish dishes, simple local preparations, and an unfussy atmosphere close to the waterfront.
Moderate for Italy. Hotels and dining are usually cheaper than Rome or Milan, while local buses and casual meals stay fairly affordable for tourists.
Service is often included or modest. Round up or leave €1-2 at cafes, 5-10% at restaurants for good service, and round up taxi fares.
Official public transport app
Via Giuseppe Maria Galanti, Brindisi -> Brindisi Railway Station, Brindisi
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Brindisi.
Find answers to the most common questions about traveling from Pisa to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

Most Pisa to Brindisi buses use the Pisa, Via delle Fiamme Gialle (Park Pietrasantina) to Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) station pair. Use this guide to compare Pisa and Brindisi bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) is 1 km from Pisa city centre. Public transport options include:
Pisa, Via delle Fiamme Gialle (Park Pietrasantina) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, Ticket Office, Bike Parking, and Bike Rental.
Wi-Fi is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina). ATMs are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Ticket office support is available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina).
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Parking, Taxis, WC.
Available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa, Via delle Fiamme Gialle (Park Pietrasantina): The station is accessible for people with reduced mobility.
Pisa (Pisamover via San Giusto/Aurelia) is 1 km from Pisa city centre. Public transport options include:
Pisa (Pisamover via San Giusto/Aurelia) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Pisa (Pisamover via San Giusto/Aurelia). ATMs are available at Pisa (Pisamover via San Giusto/Aurelia).
Ticket office support is available at Pisa (Pisamover via San Giusto/Aurelia).
Available at Pisa (Pisamover via San Giusto/Aurelia): Parking, Taxis, WC.
Accessibility facilities are available at Pisa (Pisamover via San Giusto/Aurelia): Wheelchair accessible with assistance.