Frankfurt am Main to Brindisi bus with FlixBus

Fri, Mar 20
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The cheapest and fastest buses from Frankfurt am Main to Brindisi

Showing times and prices for Mar 23

Cheapest price

$90

Average price

$132

Fastest journey

1 d 2 h 20 m

Average duration

1 d 3 h 53 m

Buses per day

8

Distance

1277 km

Cheap tickets

The best way to find a cheap bus ticket from Frankfurt am Main to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Frankfurt am Main to Brindisi will cost around $132 if you buy it on the day, but the cheapest tickets can be found for only $90.

Fast buses

It's difficult to get from Frankfurt am Main to Brindisi without transferring at least once.

FlixBusFlixBus · FlixBus · FlixBus
05:55AM29h25
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
11:20AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
$901One-way
2 transfers
FlixBusFlixBus · FlixBus · FlixBus
04:00PM30h10
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
10:10PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
$1021One-way
2 transfers
FlixTrainFlixTrain+FlixBusFlixBus · FlixBus
02:03PM32h07
Frankfurt South station
10:10PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
$1161One-way
2 transfers
FlixBusFlixBus · FlixBus
02:45PM27h40
Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
06:25PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
$1221One-way
1 transfer
FlixBusFlixBus · FlixBus
05:45PM28h25
Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
10:10PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
$1331One-way
1 transfer

Travel Information

Compare train, bus, and flight for Frankfurt am Main to Brindisi

Omio recommends booking the flight as it is the most popular option from Frankfurt am Main to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from $68. For those with little time consider booking a flight which can get you there in 2h 51m. The ticket price range depends on the travel mode: a bus costs an average of $68, and a train costs an average of $470.

Distance: 793 miles (1277 km)

Compare bus with

Bus
Most popular
Flight
Train

$135

Average price

Cheapest

$334

Average price

$470

Average price

25h 14m

Average total duration

24h 44m

Onboard

+

30m

Additional time*

5h 51m

Average total duration

Fastest

2h 51m

Onboard

+

3h 0m

Additional time*

25h 45m

Average total duration

25h 15m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Direct Options

Frankfurt am Main to Brindisi Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
01:05AM
Arrival Time
06:10AM
Duration
29h05
Departure days
Mon, Thu
Cheapest price
$169
Operator
FlixBus
Departure Time
05:55AM
Arrival Time
11:20AM
Duration
29h25
Departure days
Mon, Sun
Cheapest price
$90
Operator
Marino Autolinee
Departure Time
07:30AM
Arrival Time
09:45AM
Duration
26h15
Departure days
Thu
Cheapest price
$137
Operator
FlixBus
Departure Time
07:45AM
Arrival Time
10:05AM
Duration
26h20
Departure days
Mon, Thu, Sun
Cheapest price
$167
Operator
FlixBus
Departure Time
09:00AM
Arrival Time
05:49PM
Duration
32h49
Departure days
Thu
Cheapest price
$145
Operator
FlixBus
Departure Time
09:30AM
Arrival Time
01:25PM
Duration
27h55
Departure days
Mon, Sun
Cheapest price
$141
Operator
FlixBus
Departure Time
01:40PM
Arrival Time
06:25PM
Duration
28h45
Departure days
Thu, Sun
Cheapest price
$160
Operator
FlixBus
Departure Time
02:03PM
Arrival Time
10:10PM
Duration
32h07
Departure days
Mon, Thu
Cheapest price
$116
Operator
FlixBus
Departure Time
02:45PM
Arrival Time
06:25PM
Duration
27h40
Departure days
Mon, Thu, Sun
Cheapest price
$122
Operator
FlixBus
Departure Time
04:00PM
Arrival Time
10:10PM
Duration
30h10
Departure days
Mon, Thu
Cheapest price
$102
Operator
FlixBus
Departure Time
04:03PM
Arrival Time
10:10PM
Duration
30h07
Departure days
Sun
Cheapest price
$181
Operator
FlixBus
Departure Time
05:10PM
Arrival Time
10:10PM
Duration
29h00
Departure days
Sun
Cheapest price
$151
Operator
FlixBus
Departure Time
05:45PM
Arrival Time
10:10PM
Duration
28h25
Departure days
Mon, Thu, Sun
Cheapest price
$133

Live departures

Frankfurt am Main to Brindisi bus times

The table below shows live departures for Frankfurt am Main to Brindisi buses for today, Sunday, March 22. You can also manually refresh the results below to see updated bus journeys.

Last updated at 4:55 AM
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbusFlixBus · FlixBus · FlixBus6:45 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
26h20
9:05 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus8:30 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
27h55
12:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus12:40 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
28h45
5:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers
meinfernbus_flixbusFlixBus · FlixBus1:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
25h55
3:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)1 transfer
flixbus_flixtrainFlixTrain+meinfernbus_flixbusFlixBus · FlixBus · FlixBus3:03 PM Frankfurt South station
30h07
9:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)3 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus4:10 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
29h00
9:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers
meinfernbus_flixbusFlixBus · FlixBus4:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
28h25
9:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)1 transfer
Monday, March 23
meinfernbus_flixbusFlixBus · FlixBus · FlixBus12:05 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
29h05
5:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus4:55 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
29h25
10:20 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Frankfurt am Main to Brindisi by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Mon
Mar 23
Tue
Mar 24
Wed
Mar 25
Thu
Mar 26
Fri
Mar 27
Sat
Mar 28
Sun
Mar 29

Why should you book Frankfurt am Main to Brindisi buses with Omio?

FlixBus operates all buses services from Frankfurt am Main to Brindisi.
Omio is an official ticket reseller for all your travel options from Frankfurt am Main to Brindisi.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Frankfurt am Main to Brindisi.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Frankfurt am Main to Brindisi.

Journey information

Overview: Bus from Frankfurt am Main to Brindisi

GermanyGermany
ItalyItaly
Icon of bus

Buses from Frankfurt am Main to Brindisi run on average 7 times per day, taking around 24h 44m. Cheap bus tickets for this journey start at $68 (€55) if you book in advance.

The earliest bus runs at 00:45, the last at 23:30. The fastest bus covers the 793 miles (1277 km) distance in 25h 55m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
793 miles (1277 km)
Average bus duration
24h 44m
Cheapest ticket price
$68 (€55)
Buses per day
7
Fastest bus
25h 55m
First bus
00:45
Last bus
23:30
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus from Frankfurt am Main to BrindisiYou can travel by bus between Frankfurt am Main to Brindisi with FlixBus for as low as $68 (€55). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
25h 55m
Cheapest Price
$68 (€55)
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

FAQs: Bus from Frankfurt am Main to Brindisi

Find answers to the most common questions about traveling from Frankfurt am Main to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Frankfurt am Main to Brindisi can start from as little as $68 (€55) when you book in advance. The average bus ticket price for Frankfurt am Main to Brindisi is $135 (€110) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Frankfurt am Main to Brindisi is 25h 55m to travel the 793 miles (1277 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Frankfurt am Main to Brindisi leaves at 12:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Frankfurt am Main to Brindisi leaves at 11:30 PM.
There are 7 buses a day from Frankfurt am Main to Brindisi which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Frankfurt am Main to Brindisi, you can count on FlixBus for the best way to get you to Brindisi. You can also check all possible bus companies who offer a service between Frankfurt am Main and Brindisi and compare the amenities they offer before buying a bus ticket.
When departing from Frankfurt am Main , you have various bus station options to start your journey from including Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36), Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof), Darmstadt, Lise-Meitner-Str. / Europaplatz . When arriving in Brindisi , you can end your journey in bus stations like Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale), Mesagne, Viale Indipendenza / Via Asiago, San Vito dei Normanni, Via Carovigno / Via Oberdan (Eni) .Passengers board the bus most frequently from Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36), which is located around 10 away from the city centre, and they get off the bus at Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale), located 0 away from the city centre.
A trip to Brindisi from Frankfurt am Main is worth doing but not as a day trip with a journey time of 25h 55m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Frankfurt am Main to Brindisi is April.
It's helpful to compare your options as there are 3 ways to travel between Frankfurt am Main and Brindisi including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Frankfurt am Main to Brindisi:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Frankfurt am Main to Brindisi for bus company FlixBus.
Whether you can cancel your bus ticket from Frankfurt am Main to Brindisi depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Frankfurt am Main to Brindisi.
Yes, the following luggage options are included when booking a bus ticket from Frankfurt am Main to Brindisi:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Frankfurt am Main to Brindisi:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Frankfurt am Main to Brindisi. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Frankfurt am Main to Brindisi with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Frankfurt am Main to Brindisi with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Frankfurt am Main to Brindisi with the following bus company: FlixBus.

popular bus stations

Popular bus stations from Frankfurt am Main to Brindisi

Frankfurt am Main
Brindisi
The major bus station for departures in Frankfurt am Main is Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36). Find all the information you need to know about services, amenities and connections at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) for your trip from Frankfurt am Main to Brindisi.
Amenities at bus station
WifiWifi
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
Ticket OfficeTicket Office
information
ticketOfficeHours
Ticket Office Hours
  • 00:00-23:59
ticketOfficeHours
Distance to city center
10 km
carConnection
Car connection
Hugo-Eckener-Ring
Wifi
Wifi
  • Free Wi-Fi
Dining
Dining
  • McDonald's (in the station)
  • Hausmann's (in the station).
Taxis
Taxis
  • Available outside the terminal at designated taxi stands.
Accessibility
Accessibility
  • Elevators, ramps, assistance
WC
WC
  • Available in the station.
Public transit options for Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
  • Bus: 61, 62, 77 Train: S8, S9
Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
information

More options for your journey from Frankfurt am Main to Brindisi

Here are some other resources that might have the information you need

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