- Must visit
Museo Archeologico Provinciale Francesco Ribezzo
Main civic museum with archaeology, sculptures, and local history collections that provide the best introduction to Brindisi and its territory.
Cheapest price on Sep 19
€104
Average ticket price on Sep 19
€122
Fastest journey on Sep 19
1 d 1 h 35 m
Average journey duration on Sep 19
1 d 2 h 43 m
Buses on Sep 19
11
Distance
1277 km
The best way to find a cheap bus ticket from Frankfurt am Main to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Frankfurt am Main to Brindisi will cost around €122 if you buy it on the day, but the cheapest tickets can be found for only €104.
It's difficult to get from Frankfurt am Main to Brindisi without transferring at least once.
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixTrain+
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
254 · 043
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixTrain+
FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Frankfurt am Main to Brindisi among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €148 For those with little time, consider booking a flight, which has an average total journey time of 5h 52m. Average ticket prices depend on the travel mode: a bus costs an average of €148, while a flight costs an average of €572.
Distance: 793 miles (1277 km)
| Bus | Most popular Flight | Driving |
|---|---|---|
€148 Average price Cheapest | €572 Average price | €393 Average price (fuel + tolls) |
26h 2m Average total duration 25h 32m Onboard + 30m Additional time* | 5h 52m Average total duration Fastest 3h 52m Onboard + 2h 0m Additional time* | 16h 33m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Frankfurt am Main to Brindisi:
A bus is €423 less than a flight for this route with tickets for a flight from Frankfurt am Main to Brindisi costing on average €572.
Other travel options to Brindisi take longer:
Bus takes on average 25h 32m.
Tickets start at around €148 compared to roughly €393 in fuel and tolls — a saving of about €245. The journey takes 25h 32m versus 16h 33m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 01:05AM | Arrival Time 06:10AM | Duration 29h05 | Departure days Everyday | Cheapest price €60 |
Operator Marino Autolinee | Departure Time 07:30AM | Arrival Time 09:45AM | Duration 26h15 | Departure days Thu, Sat | Cheapest price €126 |
Operator FlixBus | Departure Time 07:50AM | Arrival Time 10:05AM | Duration 26h15 | Departure days Everyday | Cheapest price €69 |
Operator FlixBus | Departure Time 08:30AM | Arrival Time 10:05AM | Duration 25h35 | Departure days Everyday | Cheapest price €79 |
Operator FlixBus | Departure Time 09:00AM | Arrival Time 04:40PM | Duration 31h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €106 |
Operator FlixBus | Departure Time 12:03PM | Arrival Time 06:25PM | Duration 30h22 | Departure days Fri | Cheapest price €128 |
Operator FlixBus | Departure Time 01:40PM | Arrival Time 06:25PM | Duration 28h45 | Departure days Thu, Fri, Sat, Sun | Cheapest price €72 |
Operator FlixBus | Departure Time 02:03PM | Arrival Time 06:25PM | Duration 28h22 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price €87 |
Operator FlixBus | Departure Time 03:15PM | Arrival Time 06:25PM | Duration 27h10 | Departure days Everyday | Cheapest price €87 |
Operator FlixBus | Departure Time 04:00PM | Arrival Time 10:25PM | Duration 30h25 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price €75 |
Operator FlixBus | Departure Time 04:03PM | Arrival Time 10:25PM | Duration 30h22 | Departure days Sat | Cheapest price €150 |
Operator FlixBus | Departure Time 05:45PM | Arrival Time 10:25PM | Duration 28h40 | Departure days Mon, Wed, Thu, Fri, Sat, Sun | Cheapest price €86 |
Operator FlixBus | Departure Time 06:03PM | Arrival Time 10:25PM | Duration 28h22 | Departure days Fri, Sun | Cheapest price €115 |
Operator FlixBus | Departure Time 08:03PM | Arrival Time 06:10AM | Duration 34h07 | Departure days Fri | Cheapest price €122 |
The table below shows live departures for Frankfurt am Main to Brindisi buses for today, Friday, September 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixTrain+ FlixBus · FlixBus · FlixBus | 8:03 PM Frankfurt South station | 34h07 | 6:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 3 transfers | |
| Saturday, September 19 | |||||
FlixBus · FlixBus · FlixBus | 1:05 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 29h05 | 6:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
254 · 043 | 7:30 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 26h15 | 9:45 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 7:50 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 26h15 | 10:05 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:30 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 25h35 | 10:05 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 31h40 | 4:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 1:40 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 28h45 | 6:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
FlixTrain+ FlixBus · FlixBus | 2:03 PM Frankfurt South station | 28h22 | 6:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
FlixBus · FlixBus | 3:15 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 27h10 | 6:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:00 PM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) | 30h25 | 10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
FlixTrain+ FlixBus · FlixBus · FlixBus | 4:03 PM Frankfurt South station | 30h22 | 10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 3 transfers | |
FlixBus · FlixBus | 5:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) | 28h40 | 10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Frankfurt am Main to Brindisi run on average 8 times per day, taking around 25h 32m. Cheap bus tickets for this journey start at €68 if you book in advance.
The earliest bus runs at 00:45, the last at 23:30. The fastest bus covers the 793 miles (1277 km) distance in 23h 5m.
Distance 793 miles (1277 km) |
Average bus duration 25h 32m |
Cheapest ticket price €68 |
Buses per day 8 |
Fastest bus 23h 5m |
First bus 12:45 AM |
Last bus 11:30 PM |
Cheapest Month May |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Thu |
Best time to book 1 day |
Discover the best of Brindisi — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brindisi trip today.
Main civic museum with archaeology, sculptures, and local history collections that provide the best introduction to Brindisi and its territory.
Archaeological zone and small interpretive museum preserving a Roman domus with mosaics, ideal for understanding everyday life in ancient Brindisi.
Historic site museum in a circular medieval church, appreciated for architecture and exhibits linked to pilgrims, crusaders, and the city’s past.
Brindisi’s main waterfront promenade, ideal for harbor views, evening walks, and seeing the city’s maritime life at its most atmospheric.
Historic square beside the cathedral, Roman column, and staircase, making it one of the most important and scenic urban spaces in Brindisi.
Elegant central square framed by historic buildings and cafés nearby, a practical base for sightseeing and people-watching in the old town.
Rustico leccese is a flaky pastry filled with béchamel, tomato, and mozzarella. Popular across Salento, it is a beloved snack in Brindisi bars and bakeries.
Puccia salentina is a round Apulian bread sandwich, often stuffed with tuna, olives, capers, or vegetables. It is a classic street food in Brindisi and nearby Salento.
Fave e cicorie pairs creamy pureed fava beans with wild chicory. This humble Puglian staple is deeply traditional and widely eaten in Brindisi homes and trattorias.
Refined seafood restaurant in central Brindisi, known for elegant tasting menus, polished service, and creative Apulian cuisine in a stylish setting.
Well-known traditional restaurant serving Apulian seafood and local classics. Relaxed, reliable, and popular for fresh fish near the historic center.
Casual seafood spot appreciated for raw and cooked fish dishes, simple local preparations, and an unfussy atmosphere close to the waterfront.
Moderate for Italy. Hotels and dining are usually cheaper than Rome or Milan, while local buses and casual meals stay fairly affordable for tourists.
Service is often included or modest. Round up or leave €1-2 at cafes, 5-10% at restaurants for good service, and round up taxi fares.
Official public transport app
Via Giuseppe Maria Galanti, Brindisi -> Brindisi Railway Station, Brindisi
Find answers to the most common questions about traveling from Frankfurt am Main to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

Most Frankfurt am Main to Brindisi buses use the Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) to Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) station pair. Use this guide to compare Frankfurt am Main and Brindisi bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) is 10 km from Frankfurt am Main city centre. Public transport options include:
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: McDonald's (in the station), Hausmann's (in the station).
Free Wi-Fi. ATMs are located throughout the terminal, offering various banking services.
Ticket office support is available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).
Available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Parking, Taxis, WC.
Accessibility facilities are available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Elevators, ramps, assistance.
Here are some other resources that might have the information you need