Frankfurt am Main to Brindisi bus with FlixBus

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The cheapest and fastest buses from Frankfurt am Main to Brindisi

Showing times and prices for Jun 21

Cheapest price

$123

Average price

$159

Fastest journey

1 d 1 h 35 m

Average duration

1 d 3 h 8 m

Buses per day

10

Distance

1277 km

Cheap tickets

The best way to find a cheap bus ticket from Frankfurt am Main to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Frankfurt am Main to Brindisi will cost around $159 if you buy it on the day, but the cheapest tickets can be found for only $123.

Fast buses

It's difficult to get from Frankfurt am Main to Brindisi without transferring at least once.

  • FlixBusFlixBus · FlixBus · FlixBus
    7:50 AM26h15
    Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
    10:05 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
    $1231One-way
    2 transfers
  • FlixBusFlixBus · FlixBus · FlixBus
    1:05 AM29h05
    Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
    6:10 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
    $1421One-way
    2 transfers
  • FlixBusFlixBus · FlixBus
    3:15 PM27h10
    Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
    6:25 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
    $1481One-way
    1 transfer
  • FlixTrainFlixTrain+FlixBusFlixBus · FlixBus · FlixBus
    6:05 PM28h20
    Frankfurt South station
    10:25 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
    $1591One-way
    3 transfers
  • FlixBusFlixBus · FlixBus
    5:45 PM28h40
    Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
    10:25 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
    $1591One-way
    1 transfer

Travel Information

Compare train, bus, and flight for Frankfurt am Main to Brindisi

Omio recommends booking the flight as it is the most popular option from Frankfurt am Main to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from $60. For those with little time consider booking a flight which can get you there in 2h 50m. The ticket price range depends on the travel mode: a bus costs an average of $60, and a train costs an average of $489.

Distance: 793 miles (1277 km)

Compare bus with

Bus
Most popular
Flight
Train
Driving

$112

Average price

Cheapest

$335

Average price

$489

Average price

$478

Average price

(fuel + tolls)

25h 3m

Average total duration

24h 33m

Onboard

+

30m

Additional time*

5h 50m

Average total duration

Fastest

2h 50m

Onboard

+

3h 0m

Additional time*

21h 47m

Average total duration

21h 17m

Onboard

+

30m

Additional time*

16h 33m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Frankfurt am Main to Brindisi is a bus with an average price of $112 (€92).

This is compared to other travel options from Frankfurt am Main to Brindisi:

A bus is $223 (€183) less than a flight for this route with tickets for a flight from Frankfurt am Main to Brindisi costing on average $335 (€274).

A bus is $377 (€308) less than a train for this route with tickets for a train from Frankfurt am Main to Brindisi costing on average $489 (€400).

The fastest way to travel from Frankfurt am Main to Brindisi is by flight with an average journey time of 2h 50m.

Other travel options to Brindisi take longer:

Train takes on average 21h 17m.

Bus takes on average 24h 33m.

It's helpful to compare your options as there are 3 ways to travel between Frankfurt am Main and Brindisi including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Frankfurt am Main to Brindisi among Omio's users.
Take the bus. On this route, it's both cheaper and quicker than driving.

You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.

Direct coaches are operated by {directProviders}.

Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.

Frankfurt am Main to Brindisi Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
01:05AM
Arrival Time
06:10AM
Duration
29h05
Departure days
Everyday
Cheapest price
$117
Operator
Marino Autolinee
Departure Time
07:30AM
Arrival Time
09:45AM
Duration
26h15
Departure days
Thu, Sat
Cheapest price
$200
Operator
FlixBus
Departure Time
07:50AM
Arrival Time
10:05AM
Duration
26h15
Departure days
Everyday
Cheapest price
$109
Operator
FlixBus
Departure Time
08:30AM
Arrival Time
10:05AM
Duration
25h35
Departure days
Everyday
Cheapest price
$115
Operator
FlixBus
Departure Time
09:00AM
Arrival Time
04:30PM
Duration
31h30
Departure days
Mon, Thu, Fri, Sun
Cheapest price
$140
Operator
FlixBus
Departure Time
01:40PM
Arrival Time
06:25PM
Duration
28h45
Departure days
Tue, Wed, Thu, Fri, Sun
Cheapest price
$121
Operator
FlixBus
Departure Time
02:03PM
Arrival Time
06:25PM
Duration
28h22
Departure days
Everyday
Cheapest price
$103
Operator
FlixBus
Departure Time
03:15PM
Arrival Time
06:25PM
Duration
27h10
Departure days
Everyday
Cheapest price
$104
Operator
FlixBus
Departure Time
04:00PM
Arrival Time
10:25PM
Duration
30h25
Departure days
Mon, Tue, Thu
Cheapest price
$99
Operator
FlixBus
Departure Time
05:45PM
Arrival Time
10:25PM
Duration
28h40
Departure days
Everyday
Cheapest price
$122
Operator
FlixBus
Departure Time
06:05PM
Arrival Time
10:25PM
Duration
28h20
Departure days
Sun
Cheapest price
$159
Operator
FlixBus
Departure Time
08:03PM
Arrival Time
06:10AM
Duration
34h07
Departure days
Fri
Cheapest price
$159
Operator
FlixBus
Departure Time
08:04PM
Arrival Time
06:10AM
Duration
34h06
Departure days
Mon, Tue, Sun
Cheapest price
$142
Operator
FlixBus
Departure Time
08:05PM
Arrival Time
06:10AM
Duration
34h05
Departure days
Sat
Cheapest price
$174

Live departures

Frankfurt am Main to Brindisi bus times

The table below shows live departures for Frankfurt am Main to Brindisi buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBusFlixBus · FlixBus+FlixTrainFlixTrain2:03 PM Frankfurt South station
28h22
6:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers
FlixBusFlixBus · FlixBus3:15 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
27h10
6:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)1 transfer
FlixBusFlixBus · FlixBus5:45 PM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
28h40
10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)1 transfer
FlixBusFlixBus · FlixBus · FlixBus+FlixTrainFlixTrain8:05 PM Frankfurt South station
34h05
6:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)3 transfers
Sunday, June 21
FlixBusFlixBus · FlixBus · FlixBus1:05 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
29h05
6:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers
FlixBusFlixBus · FlixBus · FlixBus7:50 AM Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
26h15
10:05 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers
FlixBusFlixBus · FlixBus · FlixBus8:30 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
25h35
10:05 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers
FlixBusFlixBus · FlixBus · FlixBus9:00 AM Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
31h30
4:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale)2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Frankfurt am Main to Brindisi by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Sun
Jun 21
Mon
Jun 22
Tue
Jun 23
Wed
Jun 24
Thu
Jun 25
Fri
Jun 26
Sat
Jun 27

Why should you book Frankfurt am Main to Brindisi buses with Omio?

FlixBus operates all buses services from Frankfurt am Main to Brindisi.
Omio is an official ticket reseller for all your travel options from Frankfurt am Main to Brindisi.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Frankfurt am Main to Brindisi.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Frankfurt am Main to Brindisi.

Journey information

Overview: Bus from Frankfurt am Main to Brindisi

GermanyGermany
ItalyItaly
Icon of bus

Buses from Frankfurt am Main to Brindisi run on average 8 times per day, taking around 24h 33m. Cheap bus tickets for this journey start at $60 (€49) if you book in advance.

The earliest bus runs at 00:45, the last at 23:30. The fastest bus covers the 793 miles (1277 km) distance in 25h 55m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
793 miles (1277 km)
Average bus duration
24h 33m
Cheapest ticket price
$60 (€49)
Buses per day
8
Fastest bus
25h 55m
First bus
12:45 AM
Last bus
11:30 PM
Cheapest Month
Oct
Cheapest Day
Mon
High Season
Jul - Sep
Low Season
Jan - Mar
Best time to book
3 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus from Frankfurt am Main to BrindisiYou can travel by bus between Frankfurt am Main to Brindisi with FlixBus for as low as $60 (€49). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
25h 55m
Cheapest Price
$60 (€49)
FlixBus frequency
10 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Complete guide to Brindisi

Things to do in Brindisi

Discover the best of Brindisi — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Brindisi trip today.

  • Recommended

Museo Archeologico Provinciale Francesco Ribezzo

The city’s main archaeological museum, with finds from ancient Brundisium and the wider Salento area, including Roman and underwater archaeology.

Palazzo Granafei Nervegna

A historic palace used for exhibitions and cultural displays, also known for preserved Roman remains in its underground area.

Museo Diocesano Giovanni Tarantini

Diocesan museum with sacred art, liturgical objects, paintings, and items linked to the religious history of Brindisi.

Euro

Generally moderate by Italian standards. Dining and coffee are reasonable, while hotels cost more in peak summer.

Average meal costs

Budget
EUR 8-15 for pizza, panini, or a simple lunch.
Mid-range
EUR 20-35 per person for a casual restaurant meal.
Fine dining
EUR 50-90 per person at upscale seafood or tasting-menu spots.
Coffee
EUR 1.20-2.50 for espresso or cappuccino.

Tipping culture

Service is often included or modest. Locals may round up or leave EUR 1-2 at cafes, 5-10% at restaurants for good service, and round up taxi fares.

FAQs: Bus from Frankfurt am Main to Brindisi

Find answers to the most common questions about traveling from Frankfurt am Main to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Frankfurt am Main to Brindisi can start from as little as $60 (€49) when you book in advance. The average bus ticket price for Frankfurt am Main to Brindisi is $112 (€92) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Frankfurt am Main to Brindisi is 25h 55m to travel the 793 miles (1277 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Frankfurt am Main to Brindisi leaves at 12:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Frankfurt am Main to Brindisi leaves at 11:30 PM.
There are 8 buses a day from Frankfurt am Main to Brindisi which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Frankfurt am Main to Brindisi, you can count on FlixBus for the best way to get you to Brindisi. You can also check all possible bus companies who offer a service between Frankfurt am Main and Brindisi and compare the amenities they offer before buying a bus ticket.
When departing from Frankfurt am Main , you have various bus station options to start your journey from including Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof), Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36), Darmstadt, Lise-Meitner-Str. / Europaplatz . When arriving in Brindisi , you can end your journey in bus stations like Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale), Mesagne, Viale Indipendenza / Via Asiago, San Vito dei Normanni, Via Carovigno / Via Oberdan (Eni) .Passengers board the bus most frequently from Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36), which is located around 6 miles (10 km) away from the city centre, and they get off the bus at Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale), located 0 away from the city centre.
A trip to Brindisi from Frankfurt am Main is worth doing but not as a day trip with a journey time of 25h 55m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Frankfurt am Main to Brindisi is October.
It's helpful to compare your options as there are 3 ways to travel between Frankfurt am Main and Brindisi including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the bus from Frankfurt am Main to Brindisi:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Frankfurt am Main to Brindisi for bus company FlixBus.
Whether you can cancel your bus ticket from Frankfurt am Main to Brindisi depends on the bus companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Frankfurt am Main to Brindisi.
Yes, the following luggage options are included when booking a bus ticket from Frankfurt am Main to Brindisi:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Frankfurt am Main to Brindisi:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Frankfurt am Main to Brindisi. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Frankfurt am Main to Brindisi with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Frankfurt am Main to Brindisi with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Frankfurt am Main to Brindisi with the following bus company: FlixBus.
Since both Frankfurt am Main and Brindisi are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Frankfurt am Main to Brindisi among Omio's users.
Italy uses the euro (EUR) as its currency. Travelers generally find it convenient to use cards for most payments, especially in cities and larger establishments, but carrying some cash is advisable for small shops, markets, and rural areas where card acceptance may be limited.
In Brindisi, travelers should be cautious of pickpocketing, especially in crowded areas like the port and public transport hubs. Common scams include overpriced taxi rides and unlicensed tour operators. It's advisable to use official transportation services and remain vigilant with personal belongings in busy spots.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Frankfurt am Main to Brindisi

Most Frankfurt am Main to Brindisi buses use the Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) to Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) station pair. Use this guide to compare Frankfurt am Main and Brindisi bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Frankfurt am Main
Arrival bus stations in Brindisi
Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
City-centre transport

Getting to Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof) from Frankfurt am Main city centre

Tram12 · 10m · $4 · every ~13 min
12 · 14m · $4 · every ~13 min
Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)WifiParkingDiningATMTaxisAccessibilityWCTicket Office
City-centre transport

Getting to Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) from Frankfurt am Main city centre

Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) is 10 km from Frankfurt am Main city centre. Public transport options include:

TrainIce · 19m · $2
S9, S8 · 24m · $4 · every ~9 min
BusBlaBlaCar Bus · 15m · $1 · every ~1 min
: Amsterdam Central Sloterdijk Train Station - Prague Central Bus Station, RegioJet 540 · 30m · $1
X61, 61 · 35m · every ~13 min
61, X61 · 36m · every ~13 min

Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) bus station facilities and services

Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.

Food and drink

Food options include: McDonald's (in the station), Hausmann's (in the station).

Wi-Fi and ATMs

Free Wi-Fi. ATMs are located throughout the terminal, offering various banking services.

Tickets and information

Ticket office support is available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).

Parking, taxis and toilets

Available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36): Elevators, ramps, assistance.

More options for your journey from Frankfurt am Main to Brindisi

Here are some other resources that might have the information you need

HomeBusesBuses in ItalyBus tickets to BrindisiFrankfurt am Main to Brindisi bus

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