- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Cheapest price on Oct 25
$72
Average ticket price on Oct 25
$106
Fastest journey on Oct 25
12 h 15 m
Average journey duration on Oct 25
15 h 8 m
Buses on Oct 25
4
Distance
427 km
The best way to find a cheap bus ticket from Palermo to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Rome will cost around $106 if you buy it on the day, but the cheapest tickets can be found for only $72.
On Sun, Oct 25, we found 4 buses from Palermo to Rome, including 2 direct services.
On Sun, Oct 25 the direct buses cover the 427 km distance in an average of 15 h 8 m but if you time it right, some buses will get you there in just 12 h 15 m .
On Sun, Oct 25 the slowest buses will take 18 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
S202
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
S202
FlixBus
FlixBus · FlixBus
FlixBus · FlixBusBuses from Palermo to Rome run on average 4 times per day, taking around 14h 23m. Cheap bus tickets for this journey start at $14 (€11) but you can travel from only $11 (€10) by flight.
There are 2 buses per day. The earliest bus runs at 00:45, the last at 23:45. The fastest bus covers the 265 miles (427 km) distance in 12h 15m.
Distance 265 miles (427 km) |
Average bus duration 14h 23m |
Cheapest ticket price $14 (€11) |
Buses per day 4 |
Direct buses 2 |
Fastest bus 12h 15m |
First bus 12:45 AM |
Last bus 11:45 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Thu |
Best time to book 70 days |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Palermo to Rome.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 11:05AM | Arrival Time 05:35AM | Duration 18h30 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $74 |
Operator FlixBus | Departure Time 03:25PM | Arrival Time 06:50AM | Duration 15h25 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $97 |
Operator BlaBlaCar | Departure Time 04:20PM | Arrival Time 03:10AM | Duration 10h50 | Departure days Mon, Fri | Cheapest price $90 |
Operator Salemi | Departure Time 06:00PM | Arrival Time 06:15AM | Duration 12h15 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price $55 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 12:30PM | Duration 16h20 | Departure days Everyday | Cheapest price $54 |
The table below shows live departures for Palermo to Rome buses for tomorrow, Sunday, October 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:05 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 18h30 | 5:35 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 3:25 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 15h25 | 6:50 AM Roma, Autostazione Tiburtina | 1 transfer | |
S202 | 6:00 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 12h15 | 6:15 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 9:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 14h20 | 11:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
This is the last bus of the day. | |||||
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Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Via Marsala, Rome -> Piazza Barberini, Rome
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Rome.
Find answers to the most common questions about traveling from Palermo to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Palermo to Rome buses use the to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Palermo and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) is 3 km from Rome city centre. Public transport options include:
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Ristorante Italiano (in the station), Fast Food Express (in the station), Caffè del Terminal (in the station).
Free Wi-Fi. ATMs are located near the arrivals area.
Ticket office support is available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus).
Available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Parking, Taxis, WC.
Accessibility facilities are available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Elevators, ramps.
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