- Must visit
Vatican Museums
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Cheapest price on Sep 10
$57
Average ticket price on Sep 10
$92
Fastest journey on Sep 10
12 h 15 m
Average journey duration on Sep 10
16 h 7 m
Buses on Sep 10
5
Distance
427 km
The best way to find a cheap bus ticket from Palermo to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Rome will cost around $92 if you buy it on the day, but the cheapest tickets can be found for only $57.
On Thu, Sep 10, we found 5 buses from Palermo to Rome, including 2 direct services.
On Thu, Sep 10 the direct buses cover the 427 km distance in an average of 16 h 7 m but if you time it right, some buses will get you there in just 12 h 15 m .
On Thu, Sep 10 the slowest buses will take 20 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
S202
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
S202
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Palermo to Rome among Omio's users. If you are prioritising price, take the ferry, with an average ticket price of $71 For those with little time, consider booking a flight, which has an average total journey time of 4h 29m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a ferry costs an average of $71, while a flight costs an average of $346.
Distance: 265 miles (427 km)
| Bus | Most popular Flight | Train | Ferry |
|---|---|---|---|
$81 Average price | $346 Average price | $100 Average price | $71 Average price Cheapest |
14h 59m Average total duration 14h 29m Onboard + 30m Additional time* | 4h 29m Average total duration Fastest 2h 29m Onboard + 2h 0m Additional time* | 12h 10m Average total duration 11h 40m Onboard + 30m Additional time* | 14h 59m Average total duration 13h 59m Onboard + 1h 0m Additional time* |
0.4 - 1.1kg CO2 emissions | 1.3 - 2.6kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | ![]() Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Palermo to Rome:
A ferry is $9 (€8) less than a bus for this route with tickets for a bus from Palermo to Rome costing on average $81 (€65).
A ferry is $29 (€23) less than a train for this route with tickets for a train from Palermo to Rome costing on average $100 (€81).
A ferry is $275 (€222) less than a flight for this route with tickets for a flight from Palermo to Rome costing on average $346 (€279).
Other travel options to Rome take longer:
Train takes on average 11h 40m.
Ferry takes on average 13h 59m.
Bus takes on average 14h 29m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 09:10AM | Arrival Time 05:20AM | Duration 20h10 | Departure days Fri, Sat, Sun | Cheapest price $104 |
Operator FlixBus | Departure Time 11:05AM | Arrival Time 05:35AM | Duration 18h30 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $76 |
Operator FlixBus | Departure Time 03:25PM | Arrival Time 06:50AM | Duration 15h25 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $63 |
Operator Salemi | Departure Time 06:00PM | Arrival Time 06:15AM | Duration 12h15 | Departure days Everyday | Cheapest price $57 |
Operator Itabus | Departure Time 07:45PM | Arrival Time 09:25AM | Duration 13h40 | Departure days Mon, Sat, Sun | Cheapest price $33 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 05:15PM | Duration 20h05 | Departure days Everyday | Cheapest price $33 |
The table below shows live departures for Palermo to Rome buses for tomorrow, Thursday, September 10. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:05 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 18h30 | 5:35 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 3:25 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 15h25 | 6:50 AM Roma, Autostazione Tiburtina | 1 transfer | |
S202 | 6:00 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 12h15 | 6:15 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 9:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 20h05 | 5:15 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 9:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 14h20 | 11:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect |
Find all the dates and times for this journey
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Palermo to Rome run on average 3 times per day, taking around 14h 29m. Cheap bus tickets for this journey start at $22 (€18) but you can travel from only $11 (€9) by flight.
There are 1 buses per day. The earliest bus runs at 00:45, the last at 23:45. The fastest bus covers the 265 miles (427 km) distance in 12h 0m.
Distance 265 miles (427 km) |
Average bus duration 14h 29m |
Cheapest ticket price $22 (€18) |
Buses per day 3 |
Direct buses 1 |
Fastest bus 12h 0m |
First bus 12:45 AM |
Last bus 11:45 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Thu |
Best time to book 70 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous papal museums with the Sistine Chapel, Raphael Rooms, and major classical collections.
Outstanding ancient sculpture and mosaic museum housed in the Palazzo dei Conservatori and Palazzo Nuovo.
Celebrated villa museum with Bernini sculptures, Caravaggio paintings, and refined garden setting.
Elegant Baroque square with Bernini's fountains, lively atmosphere, and superb people-watching.
Historic square and gathering place at the Spanish Steps, ideal for classic city views and strolls.
Charming cobbled neighborhood filled with ivy-clad lanes, churches, nightlife, and local character.
Classic Roman pasta with guanciale, egg yolk, Pecorino Romano, and black pepper. A city icon known for rich flavor without cream.
Roman pasta with guanciale, tomato, and Pecorino Romano. A traditional Lazio staple tied to shepherd cooking and bold savory flavor.
Pasta with guanciale, Pecorino Romano, and black pepper. Considered one of Rome's oldest pasta dishes and prized for its simplicity.
Three-Michelin-star dining by Niko Romito at Bulgari Hotel Roma, offering refined Italian tasting menus in an elegant setting.
Historic trattoria in Testaccio known for classic Roman pasta and quinto quarto dishes in a lively, traditional setting.
Popular casual spot famed for Roman-style pizzas and fried starters. Bustling atmosphere and a long-standing local reputation.
Moderate for Europe: stays in central Rome are pricey, but transit is cheap and meals range from affordable pizza to costly tourist-area dining.
Service may be included via coperto or servizio. Round up or leave 5-10% at restaurants if service is good; round up in taxis; small change is fine at cafés.
Official public transport app
Via Marsala, Rome -> Piazza Barberini, Rome
There are several options to reach Rome from Palermo by bus: the routes proposed by three bus companies are directed from city to city or, at most, provide for a change in an intermediate city. The most frequent departures are on Mondays, the day on which five buses depart from Palermo. The duration of the journey also includes boarding and passage on the ferry that from the port of Messina reaches that of Villa San Giovanni in Calabria.
The buses that provide direct daily connections with buses Palermo Rome are the company BusCenter.it and the company SAIS Transport. The Flixbus bus also operates on the same route and offers transfers that involve a change of bus at the bus station in Taranto.
The duration of the journey to reach the city of Rome from Palermo with a journey that arrives directly at your destination goes, approximately, from 12 hours and 15 minutes to 12 hours and 45 minutes. It is different if you select a departure including change: in this case, the Palermo Roma buses take, more or less, 19 hours and 10 minutes.
The weekly runs to the capital from Palermo are on average four per day, three of which are direct and one with change: about 30 per week. The departure time for all bus lines is in the late afternoon, so most of the journey is made at night, and then arrive in Rome around 06:15.
Palermo Bus Station: the bus station in Piazza Cairoli, parallel to platform n.1 of the State Railways, can be reached by local bus 101. Here you will find refreshment points, toilets and ticket office. The Filippo Turati bus station, connected by buses 101 and 102 that take you to the centre in 15 minutes, is near a bar and a ticket office.
Arrival station: The Tiburtina bus station is connected to the centre and can be reached in about 20 minutes by bus 62 and by metro line B. Available to users: free Wi-Fi, monitor with indication of departures and arrivals, ticket office, information point, toilets, security service and parking for the disabled.
Find answers to the most common questions about traveling from Palermo to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Palermo to Rome buses use the Palermo, Via Tommaso Fazello (Terminal Bus) to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Palermo and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Cafes and vending machines available.
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Ticket office support is available at Roma, Autostazione Tiburtina.
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) is 3 km from Rome city centre. Public transport options include:
Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Ristorante Italiano (in the station), Fast Food Express (in the station), Caffè del Terminal (in the station).
Free Wi-Fi. ATMs are located near the arrivals area.
Ticket office support is available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus).
Available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Parking, Taxis, WC.
Accessibility facilities are available at Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus): Elevators, ramps.
Here are some other resources that might have the information you need