- Must visit
Vatican Museums
World-famous museum complex with the Sistine Chapel, Raphael Rooms, and major classical and Renaissance collections. Timed entry is strongly recommended due to very high demand.
Cheapest price
$61
Average price
$83
Fastest journey
12 h 15 m
Average duration
16 h 7 m
Buses per day
5
Distance
427 km
The best way to find a cheap bus ticket from Palermo to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Rome will cost around $83 if you buy it on the day, but the cheapest tickets can be found for only $61.
Of the 5 buses that leave Palermo for Rome on Fri, Jun 12, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jun 12 the direct buses cover the 427 km distance in an average of 16 h 7 m but if you time it right, some buses will get you there in just 12 h 15 m .
On Fri, Jun 12 the slowest buses will take 20 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
S202
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
S202
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Palermo to Rome among Omio's users. If you are prioritising price take the ferry with prices starting from $61. For those with little time consider booking a flight which can get you there in 5h 27m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a ferry costs an average of $61, and a flight costs an average of $25.
Distance: 265 miles (427 km)
| Bus | Most popular Flight | Train | Ferry |
|---|---|---|---|
$75 Average price | $132 Average price | $107 Average price | $69 Average price Cheapest |
11h 51m Average total duration 11h 21m Onboard + 30m Additional time* | 8h 27m Average total duration Fastest 5h 27m Onboard + 3h 0m Additional time* | 11h 0m Average total duration 10h 30m Onboard + 30m Additional time* | 14h 19m Average total duration 13h 19m Onboard + 1h 0m Additional time* |
0.4 - 1.1kg CO2 emissions | 1.3 - 2.6kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | ![]() Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Palermo to Rome:
A ferry is $7 (€5) less than a bus for this route with tickets for a bus from Palermo to Rome costing on average $75 (€61).
A ferry is $39 (€31) less than a train for this route with tickets for a train from Palermo to Rome costing on average $107 (€87).
A ferry is $64 (€52) less than a flight for this route with tickets for a flight from Palermo to Rome costing on average $132 (€108).
Other travel options to Rome take longer:
Train takes on average 10h 30m.
Bus takes on average 11h 21m.
Ferry takes on average 13h 19m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 11:05AM | Arrival Time 05:35AM | Duration 18h30 | Departure days Everyday | Cheapest price $87 |
Operator FlixBus | Departure Time 03:25PM | Arrival Time 06:50AM | Duration 15h25 | Departure days Everyday | Cheapest price $80 |
Operator Salemi | Departure Time 06:00PM | Arrival Time 06:15AM | Duration 12h15 | Departure days Everyday | Cheapest price $61 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 11:30AM | Duration 14h20 | Departure days Everyday | Cheapest price $61 |
Operator BlaBlaCar | Departure Time 10:40PM | Arrival Time 09:00AM | Duration 10h20 | Departure days Sat | Cheapest price $55 |
The table below shows live departures for Palermo to Rome buses for today, Thursday, June 11. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:05 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 18h30 | 5:35 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 3:25 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 15h25 | 6:50 AM Roma, Autostazione Tiburtina | 1 transfer | |
S202 | 6:00 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 12h15 | 6:15 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 9:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 14h20 | 11:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 9:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 20h05 | 5:15 PM Roma, Autostazione (Metro Anagnina) | 1 transfer |
Find all the dates and times for this journey
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Palermo to Rome run on average 3 times per day, taking around 11h 21m. Cheap bus tickets for this journey start at $37 (€30) but you can travel from only $25 (€20) by flight.
There are 1 buses per day. The earliest bus runs at 00:45, the last at 23:45. The fastest bus covers the 265 miles (427 km) distance in 12h 15m.
Distance 265 miles (427 km) |
Average bus duration 11h 21m |
Cheapest ticket price $37 (€30) |
Buses per day 3 |
Direct buses 1 |
Fastest bus 12h 15m |
First bus 12:45 AM |
Last bus 11:45 PM |
Cheapest Month Jun |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Tue |
Best time to book 70 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous museum complex with the Sistine Chapel, Raphael Rooms, and major classical and Renaissance collections. Timed entry is strongly recommended due to very high demand.
One of Rome’s finest art museums, known for Bernini sculptures and paintings by Caravaggio and Raphael. Advance reservation is typically required because entry is strictly timed.
The city’s historic civic museums on Capitoline Hill, featuring Roman bronzes, imperial sculpture, and art with views over the Forum.
Elegant Baroque square built on an ancient stadium, lined with fountains, palaces, and lively street life. A classic area for strolling and people-watching.
Atmospheric neighborhood of narrow lanes, ivy-covered buildings, and busy evening streets. Popular with visitors but still one of Rome’s most characteristic areas.
Famous monumental staircase linking Piazza di Spagna and Trinità dei Monti. A highly photographed landmark and social-media favorite.
A classic Roman pasta with pecorino Romano and black pepper. It is one of the city’s most iconic dishes and a benchmark of Roman cooking.
Traditional Roman pasta made with guanciale, egg yolk, pecorino Romano, and black pepper. It is famous for its rich sauce without cream.
A beloved pasta sauce of tomato, guanciale, and pecorino Romano, closely tied to Rome’s culinary identity and served with bucatini or rigatoni.
Rome’s most famous fine-dining restaurant, offering elegant tasting menus, panoramic views, and one of the city’s most prestigious dining experiences.
A historic trattoria near the Pantheon, famous for traditional Roman dishes such as gricia, amatriciana, and seasonal specialties.
A celebrated central Rome venue known for classic Roman pasta, exceptional cured meats, and a refined but lively atmosphere.
Rome is moderate by Western Europe standards: sights are affordable, but central hotels and tourist-area dining cost more.
Service is usually included or modest. Tipping is not required, but rounding up or leaving EUR 1-2 at cafes and 5-10% at restaurants for good service is appreciated.
Official public transport app
Rome, Via Marsala / Viale Enrico De Nicola -> Roma Termini
There are several options to reach Rome from Palermo by bus: the routes proposed by three bus companies are directed from city to city or, at most, provide for a change in an intermediate city. The most frequent departures are on Mondays, the day on which five buses depart from Palermo. The duration of the journey also includes boarding and passage on the ferry that from the port of Messina reaches that of Villa San Giovanni in Calabria.
The buses that provide direct daily connections with buses Palermo Rome are the company BusCenter.it and the company SAIS Transport. The Flixbus bus also operates on the same route and offers transfers that involve a change of bus at the bus station in Taranto.
The duration of the journey to reach the city of Rome from Palermo with a journey that arrives directly at your destination goes, approximately, from 12 hours and 15 minutes to 12 hours and 45 minutes. It is different if you select a departure including change: in this case, the Palermo Roma buses take, more or less, 19 hours and 10 minutes.
The weekly runs to the capital from Palermo are on average four per day, three of which are direct and one with change: about 30 per week. The departure time for all bus lines is in the late afternoon, so most of the journey is made at night, and then arrive in Rome around 06:15.
Palermo Bus Station: the bus station in Piazza Cairoli, parallel to platform n.1 of the State Railways, can be reached by local bus 101. Here you will find refreshment points, toilets and ticket office. The Filippo Turati bus station, connected by buses 101 and 102 that take you to the centre in 15 minutes, is near a bar and a ticket office.
Arrival station: The Tiburtina bus station is connected to the centre and can be reached in about 20 minutes by bus 62 and by metro line B. Available to users: free Wi-Fi, monitor with indication of departures and arrivals, ticket office, information point, toilets, security service and parking for the disabled.
Find answers to the most common questions about traveling from Palermo to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

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