- Must visit
Museo Nacional del Prado
Spain’s premier art museum, famed for masterpieces by Velázquez, Goya, and El Greco. A cornerstone of Madrid’s Golden Triangle of Art and a top priority for first-time visitors.
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The cheapest and fastest buses from Palermo to Madrid
Showing times and prices for Jun 21
Cheapest price
$274
Average price
$289
Fastest journey
2 d 1 h 20 m
Average duration
2 d 7 h 1 m
Buses per day
4
Distance
1489 km
Cheap tickets
The best way to find a cheap bus ticket from Palermo to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Madrid will cost around $289 if you buy it on the day, but the cheapest tickets can be found for only $274.
Fast buses
It's difficult to get from Palermo to Madrid without transferring at least 2 times.
FlixBus · FlixBus · FlixBus · FlixBus9:10 PM58h15Palermo, Via Tommaso Fazello (Terminal Bus)7:25 AMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)$2741One-way3 transfers- FlixBus · FlixBus · FlixBus · FlixBus9:10 PM58h45Palermo, Via Tommaso Fazello (Terminal Bus)7:55 AMMadrid, Estación Sur de Autobuses$2771One-way3 transfers
- FlixBus · FlixBus · FlixBus · FlixBus9:10 AM53h45Palermo, Via Tommaso Fazello (Terminal Bus)2:55 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)$2961One-way3 transfers
- FlixBus · FlixBus · FlixBus9:10 AM49h20Palermo, Via Tommaso Fazello (Terminal Bus)10:30 AMMadrid, Estación Sur de Autobuses$3081One-way2 transfers
- FlixBus · FlixBus · FlixBus9:10 AM49h20Palermo, Via Tommaso Fazello (Terminal Bus)10:30 AMMadrid, Estación Sur de Autobuses$3081One-way2 transfers
- FlixBus · FlixBus · FlixBus · FlixBus9:10 AM53h45Palermo, Via Tommaso Fazello (Terminal Bus)2:55 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)$2961One-way3 transfers
- FlixBus · FlixBus · FlixBus · FlixBus9:10 PM58h15Palermo, Via Tommaso Fazello (Terminal Bus)7:25 AMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)$2741One-way3 transfers
- FlixBus · FlixBus · FlixBus · FlixBus9:10 PM58h45Palermo, Via Tommaso Fazello (Terminal Bus)7:55 AMMadrid, Estación Sur de Autobuses$2771One-way3 transfers
Travel Information
Compare bus and flight for Palermo to Madrid
Omio recommends booking the flight as it is the most popular option from Palermo to Madrid among Omio's users. If you are prioritising price take the flight with prices starting from $27. For those with little time consider booking a flight which can get you there in 3h 39m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.5 - 3.7kg. The ticket price range depends on the travel mode: a flight costs an average of $27, and a bus costs an average of $135.
Distance: 925 miles (1489 km)
Compare bus with
| Bus | Most popular Flight |
|---|---|
$266 Average price | $219 Average price Cheapest |
50h 2m Average total duration 49h 32m Onboard + 30m Additional time* | 6h 39m Average total duration Fastest 3h 39m Onboard + 3h 0m Additional time* |
1.5 - 3.7kg CO2 emissions Lowest | 4.5 - 8.9kg CO2 emissions |
Most popular bus company |  Most popular airline |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Palermo to Madrid is a flight with an average price of $219 (€179).
This is compared to other travel options from Palermo to Madrid:
A flight is $47 (€39) less than a bus for this route with tickets for a bus from Palermo to Madrid costing on average $266 (€218).
The fastest way to travel from Palermo to Madrid is by flight with an average journey time of 3h 39m.
Other travel options to Madrid take longer:
Bus takes on average 49h 32m.
It's helpful to compare your options as there are 2 ways to travel between Palermo and Madrid including taking a bus and flight.
We recommend using the flight as it is the most popular way to get from Palermo to Madrid among Omio's users.
Palermo to Madrid Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 09:10AM | Arrival Time 10:30AM | Duration 49h20 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price $239 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 07:25AM | Duration 58h15 | Departure days Everyday | Cheapest price $256 |
Live departures
Palermo to Madrid bus times
The table below shows live departures for Palermo to Madrid buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus · FlixBus · FlixBus | 9:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 58h15 | 7:25 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 3 transfers | |
| FlixBus · FlixBus · FlixBus · FlixBus | 9:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 58h45 | 7:55 AM Madrid, Estación Sur de Autobuses | 3 transfers | |
| Sunday, June 21 | |||||
| FlixBus · FlixBus · FlixBus | 9:10 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 49h20 | 10:30 AM Madrid, Estación Sur de Autobuses | 2 transfers | |
| FlixBus · FlixBus · FlixBus · FlixBus | 9:10 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 53h45 | 2:55 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Palermo to Madrid by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Palermo to Madrid buses with Omio?
FlixBus operates all buses services from Palermo to Madrid.
Omio is an official ticket reseller for all your travel options from Palermo to Madrid.
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Palermo to Madrid.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Palermo to Madrid.
Journey information
Overview: Bus from Palermo to Madrid
Italy
Spain
Buses from Palermo to Madrid run on average 3 times per day, taking around 49h 32m. Cheap bus tickets for this journey start at $135 (€111) but you can travel from only $27 (€22) by flight.
The earliest bus runs at 00:40, the last at 23:50. The fastest bus covers the 925 miles (1489 km) distance in 58h 15m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $27 (€22)
Distance 925 miles (1489 km) |
Average bus duration 49h 32m |
Cheapest ticket price $135 (€111) |
Buses per day 3 |
Fastest bus 58h 15m |
First bus 12:40 AM |
Last bus 11:50 PM |
Cheapest Month Jul |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Thu |
Best time to book 5 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $27 (€22)
Bus providers: FlixBus from Palermo to MadridYou can travel by bus between Palermo to Madrid with FlixBus for as low as $27 (€22). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
58h 15m
Cheapest Price
$135 (€111)
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Complete guide to Madrid
Things to do in Madrid
Discover the best of Madrid — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Madrid trip today.
- Must visit
Museo Nacional Centro de Arte Reina Sofía
Madrid’s leading modern art museum, best known for Picasso’s Guernica alongside major works by Dalí and Miró. Essential for modern and contemporary art lovers.
- Must visit
Museo Nacional Thyssen-Bornemisza
A major museum spanning European painting from the Renaissance to the 20th century. Its broad collection complements the Prado and Reina Sofía perfectly.
- Must visit
Parque del Retiro
Madrid’s most famous park, ideal for walking, boating, and relaxing among monuments and formal gardens. A top city experience for nearly every visitor.
- Must visit
Gran Vía
Madrid’s best-known avenue, lined with historic architecture, theaters, shops, and rooftop views. Energetic by day and night, it is one of the city’s defining walks.
- Must visit
Puerta del Sol
The symbolic heart of Madrid and a major meeting point, home to the Kilómetro Cero marker and famous public celebrations. Constantly busy and central.
- Gluten-free
Cocido Madrileño
Madrid’s signature chickpea stew, traditionally served in stages with broth, vegetables, chickpeas, and assorted meats. It is one of the city’s most emblematic comfort dishes.
Bocadillo de Calamares
A classic Madrid sandwich of fried squid rings in crusty bread, especially associated with bars around Plaza Mayor. It is a simple local staple and iconic snack.
- Gluten-free
Callos a la Madrileña
A rich traditional stew made with tripe, chorizo, and morcilla in a paprika-forward sauce. It is a historic tavern dish closely linked to Madrid cuisine.
Corral de la Morería
Prestigious flamenco venue with acclaimed dining, known for refined Spanish cuisine in an intimate historic setting. It combines performance and high-end gastronomy.
Sobrino de Botín
Historic traditional restaurant famous for roast suckling pig and Castilian classics. It offers an old-world atmosphere and is one of Madrid’s most iconic dining rooms.
Casa Lucio
Well-known classic restaurant celebrated for huevos rotos and traditional Spanish cooking. It is a long-established spot with a lively, polished tavern feel.
Euro
Moderate for Western Europe. Museums and transport are reasonable, while central hotels and fine dining cost more.
Average meal costs
- Budget
- EUR 8-15 for tapas, menu del día, or fast food.
- Mid-range
- EUR 20-40 per person at a casual sit-down restaurant.
- Fine dining
- EUR 70+ per person at upscale restaurants.
- Coffee
- EUR 1.80-3.50 for espresso or cappuccino.
Tipping culture
Service is usually included. Locals often round up or leave EUR 1-2 in cafés and 5-10% at restaurants for very good service. Tipping is appreciated, not required.
Tarjeta Transporte
Get the appOfficial public transport app
Prices
- Single ticket
- EUR 1.50
- Day pass
- EUR 8.40
To the city center
Madrid, Estación Sur de Autobuses -> Puerta del Sol, Madrid
- Distance
- 4 km
- Travel time
- 20 min
- Use the Tarjeta Multi card for Metro and bus tickets; it is required for most non-contactless paper ticket products in Madrid.
- On EMT Madrid buses, you can usually pay onboard by card or mobile wallet, but Metro ticket machines are the easiest option for visitors.
FAQs: Bus from Palermo to Madrid
Find answers to the most common questions about traveling from Palermo to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Palermo to Madrid can start from as little as $135 (€111) when you book in advance. The average bus ticket price for Palermo to Madrid is $266 (€218) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Palermo to Madrid is 58h 15m to travel the 925 miles (1489 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Palermo to Madrid leaves at 12:40 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Palermo to Madrid leaves at 11:50 PM.
There are 3 buses a day from Palermo to Madrid which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Palermo to Madrid, you can count on FlixBus for the best way to get you to Madrid. You can also check all possible bus companies who offer a service between Palermo and Madrid and compare the amenities they offer before buying a bus ticket.
When departing from Palermo , you have various bus station options to start your journey from including Palermo, Via Tommaso Fazello (Terminal Bus) . When arriving in Madrid , you can end your journey in bus stations like Madrid, Estación Sur de Autobuses, Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) .Passengers board the bus most frequently from Palermo, Via Tommaso Fazello (Terminal Bus), which is located around 0 miles (1 km) away from the city centre, and they get off the bus at Madrid, Estación Sur de Autobuses, located 3 away from the city centre.
A trip to Madrid from Palermo is worth doing but not as a day trip with a journey time of 58h 15m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Palermo to Madrid is July.
It's helpful to compare your options as there are 2 ways to travel between Palermo and Madrid including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Palermo to Madrid:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Palermo to Madrid for bus company FlixBus.
Some of the most interesting sights to explore in Madrid are:
- Prado Museum, a renowned art museum housing European masterpieces from the 12th to the early 20th century
- Royal Palace of Madrid, the official residence of the Spanish royal family with opulent architecture and historical artifacts
- Retiro Park, a large and popular park in the city center featuring sculptures, a lake, and the Crystal Palace
- Plaza Mayor, a grand square surrounded by historic buildings and a hub for cultural events and markets
- Gran Vía, a bustling street known for its shopping, theaters, and vibrant nightlife.
The best things to do in Madrid include:
- Puerta del Sol, a bustling public square known for its iconic clock and vibrant atmosphere
- Mercado de San Miguel, a historic market offering a variety of gourmet foods and traditional Spanish delicacies
- Explore the vibrant nightlife in the Malasaña district, known for its eclectic bars and live music venues
- Attend a flamenco show to experience traditional Spanish dance and music
- Visit the Santiago Bernabéu Stadium, home to Real Madrid, for a tour or to catch a football match.
Whether you can cancel your bus ticket from Palermo to Madrid depends on the bus companies:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Palermo to Madrid.
Yes, the following luggage options are included when booking a bus ticket from Palermo to Madrid:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Palermo to Madrid:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Palermo to Madrid. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Palermo to Madrid with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Palermo to Madrid with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Palermo to Madrid with the following bus company: FlixBus.
Since both Palermo and Madrid are in the Schengen Area, a passport is not required for European Union (EU) or Schengen-associated country citizens. A national ID card is sufficient.
We recommend using the flight as it is the most popular way to get from Palermo to Madrid among Omio's users.
Spain uses the euro (€) as its currency. Travelers can use both cash and cards, but cards are widely accepted in cities and tourist areas, while cash may be preferred for small purchases, markets, and rural locations.
In Madrid, the main safety concerns for travelers include pickpocketing, especially in crowded areas like Puerta del Sol, Gran Vía, and on public transportation. Common scams involve distraction techniques, such as someone asking for signatures on petitions or offering friendship bracelets, to steal valuables. Travelers should also be cautious of unlicensed taxi drivers and always use official transport services. Staying vigilant in busy tourist spots and keeping belongings secure helps minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Palermo to Madrid
Most Palermo to Madrid buses use the Palermo, Via Tommaso Fazello (Terminal Bus) to Madrid, Estación Sur de Autobuses station pair, with some services arriving at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid). Use this guide to compare Palermo and Madrid bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Palermo
Arrival bus stations in Madrid
Which Madrid station do buses from Palermo arrive at?
Buses from Palermo to Madrid most often arrive at Madrid, Estación Sur de Autobuses. Some services arrive at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid), so check your ticket before travel to confirm your Madrid arrival station.
Madrid, Estación Sur de AutobusesCalle de Mendez Alvaro, 83, 28045 Madrid, Spain
City-centre transport
Getting to Madrid, Estación Sur de Autobuses from Madrid city centre
Madrid, Estación Sur de Autobuses is 3 km from Madrid city centre. Public transport options include:
TrainC5, C10, C7 · 2m · $1 · every ~23 min
C10, C7 · 8m · $1 · every ~8 min
C3, C4, C4a, C4b · 11m · $1 · every ~15 min
BusN11 · 16m · $1 · every ~11 min
N13 · 18m · $1 · every ~15 min
148 · 45m · $5 · every ~30 min
Subway6 · 24m · $2 · every ~48 min
Madrid, Estación Sur de Autobuses bus station facilities and services
Madrid, Estación Sur de Autobuses has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafetería de la estación (in the station), Restaurante El Brillante (0.5 km), La Taberna de Domínguez (0.7 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Tickets and information
Ticket office support is available at Madrid, Estación Sur de Autobuses.
Parking, taxis and toilets
Available at Madrid, Estación Sur de Autobuses: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Madrid, Estación Sur de Autobuses: Elevators, ramps.
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)Av. de la Hispanidad, s/n, 28042 Madrid, Spain
City-centre transport
Getting to Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) from Madrid city centre
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) is 12 km from Madrid city centre. Public transport options include:
Bus203, N27 · 1h 2m · $11 · every ~45 min
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) bus station facilities and services
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) has practical services for this route, including Dining, ATM, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Rodilla, Mahoudrid
Wi-Fi and ATMs
ATMs are aTMs located throughout T4, major cards accepted .
Tickets and information
Ticket office support is available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid).
Parking, taxis and toilets
Available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): WC.
Accessibility
Accessibility facilities are available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): Step-free access, elevators, accessible toilets.
Most popular bus connections from Palermo
More options for your journey from Palermo to Madrid
Here are some other resources that might have the information you need
Most popular buses to and from Madrid and Palermo
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