- Must visit
Museo del Prado
World-class art museum with masterpieces by Velázquez, Goya, and Bosch; essential for Spanish and European painting.
Cheapest price
€234
Average price
€259
Fastest journey
2 d 10 h 15 m
Average duration
2 d 10 h 30 m
Buses per day
2
Distance
1489 km
The best way to find a cheap bus ticket from Palermo to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Madrid will cost around €259 if you buy it on the day, but the cheapest tickets can be found for only €234.
It's difficult to get from Palermo to Madrid without transferring at least 3 times.
FlixBus · FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus · FlixBus
FlixBus · FlixBus · FlixBus · FlixBusOmio recommends booking the flight as it is the most popular option from Palermo to Madrid among Omio's users. If you are prioritising price take the flight with prices starting from €22. For those with little time consider booking a flight which can get you there in 3h 39m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.5 - 3.7kg. The ticket price range depends on the travel mode: a flight costs an average of €22, and a bus costs an average of €111.
Distance: 925 miles (1489 km)
| Bus | Most popular Flight |
|---|---|
€218 Average price | €179 Average price Cheapest |
50h 2m Average total duration 49h 32m Onboard + 30m Additional time* | 6h 39m Average total duration Fastest 3h 39m Onboard + 3h 0m Additional time* |
1.5 - 3.7kg CO2 emissions Lowest | 4.5 - 8.9kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Palermo to Madrid:
A flight is €39 less than a bus for this route with tickets for a bus from Palermo to Madrid costing on average €218.
Other travel options to Madrid take longer:
Bus takes on average 49h 32m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 09:10AM | Arrival Time 10:30AM | Duration 49h20 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price €186 |
Operator FlixBus | Departure Time 09:10PM | Arrival Time 07:55AM | Duration 58h45 | Departure days Everyday | Cheapest price €171 |
The table below shows live departures for Palermo to Madrid buses for today, Tuesday, August 4. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus · FlixBus | 9:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 58h45 | 7:55 AM Madrid, Estación Sur de Autobuses | 3 transfers | |
FlixBus · FlixBus · FlixBus · FlixBus | 9:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 58h15 | 7:25 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 3 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Palermo to Madrid run on average 3 times per day, taking around 49h 32m. Cheap bus tickets for this journey start at €111 but you can travel from only €22 by flight.
The earliest bus runs at 00:40, the last at 23:50. The fastest bus covers the 925 miles (1489 km) distance in 58h 15m.
Distance 925 miles (1489 km) |
Average bus duration 49h 32m |
Cheapest ticket price €111 |
Buses per day 3 |
Fastest bus 58h 15m |
First bus 12:40 AM |
Last bus 11:50 PM |
Cheapest Month Jul |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Thu |
Best time to book 5 days |
Discover the best of Madrid — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Madrid trip today.
World-class art museum with masterpieces by Velázquez, Goya, and Bosch; essential for Spanish and European painting.
Leading modern art museum best known for Picasso’s Guernica, plus major works by Dalí and Miró.
Celebrated collection of European masters from Van Eyck to Hopper in a refined palace setting.
Madrid’s most famous park offers gardens, a boating lake, monuments, and relaxed walks in the city center.
Lively grand avenue known for architecture, shopping, theaters, and nonstop energy from day to night.
Elegant boulevard linking major museums and landmarks, ideal for a classic central Madrid walk.
A hearty chickpea stew with meats, vegetables, and broth, especially traditional in Madrid and often served in stages.
Crisp fried squid rings served in a baguette roll. This iconic Madrid street food is especially linked to bars around Plaza Mayor.
Tripe stew with chorizo and morcilla in a rich sauce. A classic old Madrid tavern dish with deep local roots.
Refined two-Michelin-star dining focused on seasonal Spanish produce, with elegant modern cooking in a polished fine-dining room.
Traditional Madrid restaurant known for cocido madrileño served in stages, with an old-school dining room and loyal local following.
Historic century-old tavern famed for roast suckling pig and Castilian dishes in a classic, wood-lined setting near Plaza Mayor.
Moderate for Western Europe: hotels vary, dining is reasonable, and public transport is good value for tourists.
Tipping is modest: round up or leave 5-10% in restaurants for good service. Taxis are usually rounded up. In cafés, small change is enough.
Official public transport app
Madrid Estación Sur de Autobuses -> Puerta del Sol
Find answers to the most common questions about traveling from Palermo to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

Most Palermo to Madrid buses use the Palermo, Via Tommaso Fazello (Terminal Bus) to Madrid, Estación Sur de Autobuses station pair, with some services arriving at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid). Use this guide to compare Palermo and Madrid bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Madrid, Estación Sur de Autobuses is 3 km from Madrid city centre. Public transport options include:
Madrid, Estación Sur de Autobuses has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Cafetería de la estación (in the station), Restaurante El Brillante (0.5 km), La Taberna de Domínguez (0.7 km).
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Ticket office support is available at Madrid, Estación Sur de Autobuses.
Available at Madrid, Estación Sur de Autobuses: Parking, Taxis, WC.
Accessibility facilities are available at Madrid, Estación Sur de Autobuses: Elevators, ramps.
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) is 12 km from Madrid city centre. Public transport options include:
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) has practical services for this route, including Dining, ATM, Accessibility, WC, Shower, and Ticket Office.
Food options include: Rodilla, Mahoudrid
ATMs are aTMs located throughout T4, major cards accepted .
Ticket office support is available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid).
Available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): WC.
Accessibility facilities are available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): Step-free access, elevators, accessible toilets.
Here are some other resources that might have the information you need