The cheapest and fastest buses from Milan to Brindisi
Cheapest price
$44
Average price
$69
Fastest journey
10 h 40 m
Average duration
12 h 30 m
Buses per day
26
Distance
890 km
The best way to find a cheap bus ticket from Milan to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Brindisi will cost around $69 if you buy it on the day, but the cheapest tickets can be found for only $44.
Of the 26 buses that leave Milan for Brindisi on Sat, Feb 28, 7 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Feb 28 the direct buses cover the 890 km distance in an average of 12 h 30 m but if you time it right, some buses will get you there in just 10 h 40 m .
On Sat, Feb 28 the slowest buses will take 13 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
043
043
3803 · 1107
2421 · 1103
3803 · 1107
043
102 · 108
201 · 207
043Travel Information
Compare bus, train, and flight for Milan to Brindisi
Omio recommends booking the flight as it is the most popular option from Milan to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from $20. For those with little time consider booking a flight which can get you there in 1h 43m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.3 - 0.8kg. The ticket price range depends on the travel mode: a bus costs an average of $20, and a flight costs an average of $22.
Distance: 553 miles (890 km)
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
$49 Average price Cheapest | $134 Average price | $91 Average price |
13h 27m Average total duration 12h 57m Onboard + 30m Additional time* | 4h 43m Average total duration Fastest 1h 43m Onboard + 3h 0m Additional time* | 11h 29m Average total duration 10h 59m Onboard + 30m Additional time* |
0.9 - 2.2kg CO2 emissions | - CO2 emissions | 0.3 - 0.8kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Milan to Brindisi Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:35AM | Arrival Time 06:25PM | Duration 17h50 | Departure days Mon, Tue, Wed, Thu | Cheapest price $62 |
Operator FlixBus | Departure Time 01:10AM | Arrival Time 06:25PM | Duration 17h15 | Departure days Mon, Tue, Wed, Thu | Cheapest price $63 |
Operator FlixBus | Departure Time 07:25AM | Arrival Time 10:10PM | Duration 14h45 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $44 |
Operator BlaBlaCar | Departure Time 08:00AM | Arrival Time 06:40PM | Duration 10h40 | Departure days Sat | Cheapest price $83 |
Operator FlixBus | Departure Time 08:15AM | Arrival Time 10:10PM | Duration 13h55 | Departure days Mon, Tue, Thu, Fri, Sat, Sun | Cheapest price $44 |
Operator Marino Autolinee | Departure Time 08:25AM | Arrival Time 10:10PM | Duration 13h45 | Departure days Everyday | Cheapest price $46 |
Operator Marino Autolinee | Departure Time 09:10AM | Arrival Time 10:10PM | Duration 13h00 | Departure days Everyday | Cheapest price $46 |
Operator FlixBus | Departure Time 10:10AM | Arrival Time 07:15AM | Duration 21h05 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $60 |
Operator FlixBus | Departure Time 11:55AM | Arrival Time 07:15AM | Duration 19h20 | Departure days Wed | Cheapest price $77 |
Operator FlixBus | Departure Time 12:25PM | Arrival Time 06:10AM | Duration 17h45 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $36 |
Operator FlixBus | Departure Time 12:40PM | Arrival Time 07:15AM | Duration 18h35 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $45 |
Operator FlixBus | Departure Time 12:45PM | Arrival Time 06:10AM | Duration 17h25 | Departure days Mon, Wed, Fri | Cheapest price $44 |
Operator Itabus | Departure Time 12:50PM | Arrival Time 07:30AM | Duration 18h40 | Departure days Mon, Fri, Sat, Sun | Cheapest price $29 |
Operator Itabus | Departure Time 01:35PM | Arrival Time 07:30AM | Duration 17h55 | Departure days Mon, Fri, Sat, Sun | Cheapest price $29 |
Operator FlixBus | Departure Time 03:25PM | Arrival Time 10:05AM | Duration 18h40 | Departure days Everyday | Cheapest price $84 |
Operator FlixBus | Departure Time 06:25PM | Arrival Time 10:05AM | Duration 15h40 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $45 |
Operator Marino Autolinee | Departure Time 06:50PM | Arrival Time 08:25AM | Duration 13h35 | Departure days Everyday | Cheapest price $38 |
Operator FlixBus | Departure Time 07:10PM | Arrival Time 10:05AM | Duration 14h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $45 |
Operator Marino Autolinee | Departure Time 07:35PM | Arrival Time 08:25AM | Duration 12h50 | Departure days Everyday | Cheapest price $38 |
Operator Marino Autolinee | Departure Time 08:25PM | Arrival Time 09:45AM | Duration 13h20 | Departure days Everyday | Cheapest price $38 |
Operator FlixBus | Departure Time 09:00PM | Arrival Time 05:49PM | Duration 20h49 | Departure days Everyday | Cheapest price $52 |
Operator FlixBus | Departure Time 09:05PM | Arrival Time 11:20AM | Duration 14h15 | Departure days Everyday | Cheapest price $44 |
Operator Marino Autolinee | Departure Time 09:05PM | Arrival Time 09:45AM | Duration 12h40 | Departure days Everyday | Cheapest price $38 |
Operator Itabus | Departure Time 09:35PM | Arrival Time 04:30PM | Duration 18h55 | Departure days Thu, Fri, Sat, Sun | Cheapest price $45 |
Operator FlixBus | Departure Time 09:50PM | Arrival Time 11:20AM | Duration 13h30 | Departure days Everyday | Cheapest price $44 |
Operator Itabus | Departure Time 10:30PM | Arrival Time 04:30PM | Duration 18h00 | Departure days Thu, Fri, Sat, Sun | Cheapest price $43 |
Operator FlixBus | Departure Time 10:45PM | Arrival Time 04:40PM | Duration 17h55 | Departure days Fri, Sat, Sun | Cheapest price $68 |
Operator FlixBus | Departure Time 11:05PM | Arrival Time 06:25PM | Duration 19h20 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $53 |
Operator FlixBus | Departure Time 11:20PM | Arrival Time 04:40PM | Duration 17h20 | Departure days Fri, Sat, Sun | Cheapest price $68 |
Operator FlixBus | Departure Time 11:50PM | Arrival Time 06:25PM | Duration 18h35 | Departure days Mon, Tue, Wed, Thu, Sat, Sun | Cheapest price $53 |
Live departures
Milan to Brindisi bus times
The table below shows live departures for Milan to Brindisi buses for today, Friday, February 27. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 5:25 PM Milano, Autostazione Lampugnano | 15h40 | 9:05 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
102 · 108 | 5:50 PM Milano, Autostazione Lampugnano | 13h35 | 7:25 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 6:10 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 14h55 | 9:05 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
102 · 108 | 6:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 12h50 | 7:25 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
043 | 7:25 PM Milano, Autostazione Lampugnano | 13h20 | 8:45 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 8:00 PM Milano, Milan Linate Airport | 20h49 | 4:49 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
FlixBus | 8:05 PM Milano, Autostazione Lampugnano | 14h15 | 10:20 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
043 | 8:05 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 12h40 | 8:45 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
2421 · 1103 | 8:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 18h55 | 3:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus | 8:50 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 13h30 | 10:20 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
3897 · 1103 | 9:30 PM Milano, Autostazione Lampugnano | 18h00 | 3:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
3897A · 1103 | 9:30 PM Milano, Autostazione Lampugnano | 18h00 | 3:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 9:45 PM Milano, Autostazione Lampugnano | 17h55 | 3:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 10:20 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 17h20 | 3:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
| Saturday, February 28 | |||||
FlixBus | 6:25 AM Milano, Autostazione Lampugnano | 14h45 | 9:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
FlixBus | 7:15 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 13h55 | 9:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
201 · 207 | 7:25 AM Milano, Autostazione Lampugnano | 13h45 | 9:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
201 · 207 | 8:10 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 13h00 | 9:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:10 AM Milano, Milan Linate Airport | 20h00 | 5:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
FlixBus · FlixBus | 11:25 AM Milano, Autostazione Lampugnano | 17h45 | 5:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 11:40 AM Milano, Autostazione Lampugnano | 18h35 | 6:15 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
3803 · 1107 | 11:50 AM Milano, Autostazione Lampugnano | 18h40 | 6:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
3803 · 1107 | 12:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 17h55 | 6:30 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 2:25 PM Milano, Milan Linate Airport | 18h40 | 9:05 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan to Brindisi by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 27
Feb 28
Mar 01
Mar 02
Mar 03
Mar 04
Mar 05
Mar 06
Mar 07
Mar 08
Mar 09
Mar 10
Mar 11
Mar 12
Mar 13
Mar 14
Mar 15
Mar 16
Mar 17
Mar 18
Mar 19
Why should you book Milan to Brindisi buses with Omio?
Why book with Omio vs Marino Autolinee?
- Compare with other providers: On Omio, you can not only buy tickets for Marino Autolinee, but also compare tickets for the likes of Itabus or FlixBus to find the best option for your trip from Milan to Brindisi.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Marino Autolinee with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Milan to Brindisi.
Why book with Omio over Checkmybus, Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus or FlixBus to find the best option for your trip from Milan to Brindisi.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Milan to Brindisi.
Journey information
Overview: Bus from Milan to Brindisi
Buses from Milan to Brindisi run on average 25 times per day, taking around 12h 57m. Cheap bus tickets for this journey start at $20 (€16) if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 553 miles (890 km) distance in 12h 40m.
Distance 553 miles (890 km) |
Average bus duration 12h 57m |
Cheapest ticket price $20 (€16) |
Buses per day 25 |
Direct buses 6 |
Fastest bus 12h 40m |
First bus 00:10 |
Last bus 23:55 |
Bus providers: Marino Autolinee, Itabus, FlixBus, BlaBlaCar from Milan to BrindisiYou can travel by bus between Milan to Brindisi with Marino Autolinee, Itabus, FlixBus, BlaBlaCar for as low as $20 (€16). When you search for schedules and tickets, Omio will show you the best journey
Marino Autolinee
Itabus
FlixBus
BlaBlaCar
FAQs: Bus from Milan to Brindisi
Find answers to the most common questions about traveling from Milan to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Milan to Brindisi
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M1 Bus: 68, 78, 80
- 06:00-22:00
- Free Wi-Fi
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Bus: 121, 132 Metro: M3
More options for your journey from Milan to Brindisi
Here are some other resources that might have the information you need



