Madrid to Pisa bus

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Overview: Bus from Madrid to Pisa

distanceDistance755 miles (1218 km)
frequencyBus frequency1 a day
changesDirect busNo
carriersBus providersFlixbus

Buses from Madrid to Pisa cover the 755 miles (1218 km) long journey taking on average 39 h 50 min with our travel partners like Flixbus. Normally, there is 1 bus operating per day, including direct services available. Travelers depart most frequently from Madrid-Puerta de Atocha and arrive in Pisa, Via delle Fiamme Gialle (Park Pietrasantina).

Bus providers: FlixBus from Madrid to Pisa

Travel between Madrid and Pisa on FlixBus buses with Omio. When comparing schedules and tickets, we will also show you other options with multiple connections or other travel modes if they’re available.


FlixBus is one of Europe's leading low-cost bus companies, founded in Germany and offering long-distance bus services in Europe and the U. S. FlixBus also operates overnight buses on select routes throughout Europe. Standard amenities on FlixBus include free Wi-Fi, power outlets to charge your phone, tablet or laptop during long bus journeys, extra legroom, luggage space and toilets. You can even purchase snacks and drinks onboard. FlixBus offers only the Standard ticket for all its routes, which allows you to bring one carry-on luggage and one checked bag per person. Additional fees apply for extra luggage and specific seat reservations, such as if you want to book an Extra Seat, Table Seat or the Panorama Seat.

Madrid to Pisa bus information with FlixBus:

  • Average Duration: 39 h 50 min
  • FlixBus frequency: 1 a day

Travel Tips: Bus to Pisa from Madrid

Travel Tips: Take the bus to Pisa easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Madrid to Pisa.

Travel between Madrid, Spain and Pisa, Italy by bus is: Unrestricted.

What is the status of international entry into Italy from Spain?

International entry status: Entry is unrestricted for citizens and permanent residents of Spain

Do I need to self-quarantine on arrival in Italy from Madrid?

Conditions of entry:

  • There are no current restrictions

What are the safety rules to follow in Pisa, Italy?

When traveling in Italy, you must follow these COVID-19 safety rules:

  • Physical distance requirement: 1.5 metre (s) (5 feet)
  • Face mask requirement: Mandatory

The information above was last checked on 10/3/22. This can change before your date of travel so please review the latest COVID-19 travel safety regulations   for your bus to Pisa from Madrid before traveling.

The current restriction level for your return trip by bus from Pisa to Madrid is: Unrestricted

Are there any international entry restrictions on returning to Spain from Italy?

Reentry to Spain is allowed for: Entry is unrestricted for citizens and permanent residents of Italy

Do I need to quarantine on arrival in Spain from Pisa?

What are the requirements?

  • There are no current restrictions

What are the safety rules to follow in Madrid, Spain?

The government of Spain has imposed these measures to reduce the spread of COVID-19:

  • Physical distance: 1.5 metre (s) (5 feet)
  • Face mask: Mandatory

Last checked on 10/3/22. We do our best to keep this information up to date, but regulations can change so please double check the latest COVID-19 travel safety regulations ahead of your bus to Madrid from Pisa here.

When traveling this route you should expect the distance to Pisa from Madrid by bus to be approximately 755 miles (1218 km).
The bus time from Madrid to Pisa is on average 39 h 50 min  for the 755 miles (1218 km) long journey, but the time it takes to go to Pisa from Madrid by bus can vary depending on specific dates or traveling on weekends and holidays.

Some of the Madrid bus stations to Pisa you can start your journey from include Madrid, Estación Sur/Gare routière Méndez Alvaro - 83, Madrid, Estación de Moncloa and Madrid, Méndez Álvaro - Terminal. Similarly, some of the arrival bus stations in Pisa include Pisa, Via delle Fiamme Gialle (Park Pietrasantina), Pisa, Staz. FS and Pisa, Via Giuseppe Sainati.

When traveling this route, Omio customers are departing most frequently from Madrid-Puerta de Atocha   and arriving in Pisa, Via delle Fiamme Gialle (Park Pietrasantina).

Passengers board their bus most frequently from Madrid-Puerta de Atocha and travel around 1.4 miles (2.2 km) from the city center to this bus station.

Passengers traveling this route most often arrive at Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and need to travel approximately 1 mile (1.6 km) from the bus station to the city center in Pisa.

For the journey from Madrid to Pisa you can take a bus with Flixbus. Be sure to check out all possible bus providers that offer services between Madrid and Pisa on Omio to compare what amenities they may have.
The average number of buses departing Madrid for Pisa is 1 a day. The bus schedules and services may vary between weekdays and weekends.
The first Madrid to Pisa bus departs at 7: 35 PM   and the last bus from Madrid to Pisa leaves at 7: 35 PM. Check out the most up-to-date bus schedule from Madrid to Pisa on Omio and find the best time to travel to your destination.

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