The cheapest and fastest buses from Independence, MO to St. Louis, MO
Cheapest price
$148
Average price
$148
Fastest journey
5 h 32 m
Average duration
6 h 1 m
Buses per day
5
Distance
369 km
The best way to find a cheap bus ticket from Independence, MO to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Independence, MO to St. Louis, MO will cost around $148 if you buy it on the day, but the cheapest tickets can be found for only $148.
It's difficult to get from Independence, MO to St. Louis, MO without transferring at least once.










Travel Information
Compare train, bus, and flight for Independence, MO to St. Louis, MO
Omio recommends booking the train as it is the most popular option from Independence, MO to St. Louis, MO among Omio's users. If you are prioritising price take the train with prices starting from €35. For those with little time consider booking a bus which can get you there in 3h 55m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a train costs an average of €35, and a flight costs an average of €334.
Distance: 229 miles (369 km)
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€41 Average price | €37 Average price Cheapest | €334 Average price |
4h 25m Average total duration Fastest 3h 55m Onboard + 30m Additional time* | 5h 51m Average total duration 5h 21m Onboard + 30m Additional time* | 9h 14m Average total duration 6h 14m Onboard + 3h 0m Additional time* |
0.4 - 0.9kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 1.1 - 2.2kg CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Independence, MO to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:00AM | Arrival Time 12:05PM | Duration 6h05 | Departure days Tue | Cheapest price $53 |
Operator Greyhound | Departure Time 08:40AM | Arrival Time 12:55PM | Duration 4h15 | Departure days Tue | Cheapest price $67 |
Operator Greyhound | Departure Time 03:50PM | Arrival Time 10:55PM | Duration 7h05 | Departure days Tue | Cheapest price $55 |
Operator Greyhound | Departure Time 06:50PM | Arrival Time 10:50PM | Duration 4h00 | Departure days Tue | Cheapest price $54 |
Live departures
Independence, MO to St. Louis, MO bus times
The table below shows live departures for Independence, MO to St. Louis, MO buses for today, Tuesday, February 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:50 PM Kansas City, Jefferson Lines | 7h05 | 4:55 AM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
| Wednesday, February 4 | |||||
![]() | 12:50 AM Kansas City, Jefferson Lines | 4h00 | 4:50 AM St. Louis, S 15th St (Civic center) | 0 transfersDirect | |
![]() | 4:19 AM Independence, MO | 7h46 | 12:05 PM St. Louis, MO | 2 transfers | |
![]() | 4:19 AM Independence, MO | 7h46 | 12:05 PM St. Louis, MO | 1 transfer | |
![]() | 7:18 AM Independence, MO | 5h37 | 12:55 PM St. Louis, MO | 2 transfers | |
![]() | 7:18 AM Independence, MO | 5h37 | 12:55 PM St. Louis, MO | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Independence, MO to St. Louis, MO by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 04
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Feb 10
Why should you book Independence, MO to St. Louis, MO buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of Ride KC to find the best option for your trip from Independence, MO to St. Louis, MO.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Independence, MO to St. Louis, MO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Independence, MO to St. Louis, MO.
Journey information
Overview: Bus from Independence, MO to St. Louis, MO
Buses from Independence, MO to St. Louis, MO run on average 4 times per day, taking around 3h 55m. Cheap bus tickets for this journey start at $47 (€37) but you can travel from only $44 (€35) by train.
There are 4 buses per day. The earliest bus runs at 01:00, the last at 18:50. The fastest bus covers the 229 miles (369 km) distance in 4h 0m.
Distance 229 miles (369 km) |
Average bus duration 3h 55m |
Cheapest ticket price $47 (€37) |
Buses per day 4 |
Direct buses 4 |
Fastest bus 4h 0m |
First bus 01:00 |
Last bus 18:50 |
Bus providers: Greyhound, Ride KC from Independence, MO to St. Louis, MOYou can travel by bus between Independence, MO to St. Louis, MO with Greyhound, Ride KC for as low as $44 (€35). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
Ride KC
FAQs: Bus from Independence, MO to St. Louis, MO
Find answers to the most common questions about traveling from Independence, MO to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Independence, MO to St. Louis, MO
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