- Must visit
Saint Louis Art Museum
Vast art museum in Forest Park with global collections from antiquity to modern works and strong free general admission.
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The cheapest and fastest buses from Independence, MO to St. Louis, MO
Showing times, prices and bookable tickets for Sep 20
Cheapest price on Sep 20
$56
Average ticket price on Sep 20
$56
Fastest journey on Sep 20
6 h 5 m
Average journey duration on Sep 20
6 h 5 m
Buses on Sep 20
1
Distance
369 km
Cheap tickets
The best way to find a cheap bus ticket from Independence, MO to St. Louis, MO is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Independence, MO to St. Louis, MO will cost around $56 if you buy it on the day, but the cheapest tickets can be found for only $56.
Fast buses
On Sun, Sep 20, we found 1 buses from Independence, MO to St. Louis, MO, including 1 direct services.
On Sun, Sep 20 the direct buses cover the 369 km distance in an average of 6 h 5 m but if you time it right, some buses will get you there in just 6 h 5 m .
On Sun, Sep 20 the slowest buses will take 6 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
11:00 AM6h05Independence, MO5:05 PMSt. Louis, MO$561One-way0 transfers
- 11:00 AM6h05Independence, MO5:05 PMSt. Louis, MO$561One-way0 transfers
Travel Information
Compare train and bus for Independence, MO to St. Louis, MO
Omio recommends booking the flight as it is the most popular option from Independence, MO to St. Louis, MO among Omio's users. If you are prioritising price, take the train, with an average ticket price of $55 For those with little time, consider booking a bus, which has an average total journey time of 5h 51m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a train costs an average of $55, while a flight costs an average of $651.
Distance: 229 miles (369 km)
Compare bus with
| Bus | Most popular Flight | Train | Driving |
|---|---|---|---|
$71 Average price | $651 Average price | $55 Average price Cheapest | $49 Average price (fuel + tolls) |
5h 51m Average total duration Fastest 5h 21m Onboard + 30m Additional time* | 6h 0m Average total duration 4h 0m Onboard + 2h 0m Additional time* | 5h 51m Average total duration 5h 21m Onboard + 30m Additional time* | 3h 44m Average total duration (door-to-door) |
0.4 - 0.9kg CO2 emissions | 1.1 - 2.2kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions |
Most popular bus company |  Most popular airline |  Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
The cheapest way to travel from Independence, MO to St. Louis, MO is a train with an average price of $55.
This is compared to other travel options from Independence, MO to St. Louis, MO:
A train is $16 less than a bus for this route with tickets for a bus from Independence, MO to St. Louis, MO costing on average $71.
A train is $595 less than a flight for this route with tickets for a flight from Independence, MO to St. Louis, MO costing on average $651.
The fastest way to travel from Independence, MO to St. Louis, MO is by flight with an average journey time of 4h 0m.
Other travel options to St. Louis, MO take longer:
Train takes on average 5h 21m.
Bus takes on average 5h 21m.
It's helpful to compare your options as there are 2 ways to travel between Independence, MO and St. Louis, MO including taking a train and bus.
We recommend using the flight as it is the most popular way to get from Independence, MO to St. Louis, MO among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.
Tickets start at around $71 compared to roughly $49 in fuel and tolls — a saving of about $-21.82. The journey takes 5h 21m versus 3h 44m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Independence, MO to St. Louis, MO Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:50AM | Arrival Time 04:50AM | Duration 4h00 | Departure days Tue, Wed, Thu, Sun | Cheapest price $43 |
Operator Greyhound | Departure Time 11:00AM | Arrival Time 05:05PM | Duration 6h05 | Departure days Thu, Fri, Sun | Cheapest price $56 |
Operator Greyhound | Departure Time 12:00PM | Arrival Time 06:05PM | Duration 6h05 | Departure days Fri | Cheapest price $57 |
Operator Greyhound | Departure Time 01:40PM | Arrival Time 05:55PM | Duration 4h15 | Departure days Sat | Cheapest price $46 |
Operator Greyhound | Departure Time 08:50PM | Arrival Time 03:55AM | Duration 7h05 | Departure days Thu, Fri | Cheapest price $73 |
Operator Greyhound | Departure Time 11:50PM | Arrival Time 03:50AM | Duration 4h00 | Departure days Tue, Thu | Cheapest price $45 |
Live departures
Independence, MO to St. Louis, MO bus times
The table below shows live departures for Independence, MO to St. Louis, MO buses for today, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 1:40 PM Independence, MO | 4h15 | 5:55 PM St. Louis, MO | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Independence, MO to St. Louis, MO by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Independence, MO to St. Louis, MO buses with Omio?
Greyhound operates all buses services from Independence, MO to St. Louis, MO.
Omio is an official ticket reseller for all your travel options from Independence, MO to St. Louis, MO.
Why book with Omio vs Greyhound?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are train and bus to ensure you get the best deal for traveling from Independence, MO to St. Louis, MO.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Independence, MO to St. Louis, MO.
Journey information
Overview: Bus from Independence, MO to St. Louis, MO
USAUSA
Buses from Independence, MO to St. Louis, MO run on average 4 times per day, taking around 5h 21m. Cheap bus tickets for this journey start at $44 but you can travel from only $39 by train.
There are 4 buses per day. The earliest bus runs at 01:00, the last at 18:50. The fastest bus covers the 229 miles (369 km) distance in 4h 0m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $39
Distance 229 miles (369 km) |
Average bus duration 5h 21m |
Cheapest ticket price $44 |
Buses per day 4 |
Direct buses 4 |
Fastest bus 4h 0m |
First bus 1:00 AM |
Last bus 6:50 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Oct - Dec |
Busiest Day Fri |
Least Busy Day Fri |
Best time to book 6 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from $39
Bus providers: Greyhound from Independence, MO to St. Louis, MOYou can travel by bus between Independence, MO to St. Louis, MO with Greyhound for as low as $39. When you search for schedules and tickets, Omio will show you the best journey
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
4h 0m
Cheapest Greyhound Price
$44
Greyhound frequency
4 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to St. Louis, MO
Things to do in St. Louis, MO
Discover the best of St. Louis, MO — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis, MO trip today.
- Recommended
Missouri History Museum
Leading history museum covering St. Louis, Missouri, and national stories through rotating exhibitions in Forest Park.
- Recommended
Saint Louis Science Center
Interactive science museum with hands-on exhibits, planetarium, and family-friendly displays near Forest Park.
- Must visit
Gateway Arch National Park Grounds
Lively downtown riverfront district with trails, views of the Arch, public art, and access to major historic sites.
- Must visit
Forest Park
Large urban park with trails, lakes, zoo access, and major museums, ideal for walking between top attractions.
- Recommended
Tower Grove Park
Beloved neighborhood park with formal lily ponds, pavilions, and one of the city's most photographed landscapes.
- Vegetarian
St. Louis-Style Pizza
A thin, cracker-like crust pizza cut into squares and topped with Provel cheese, a St. Louis original loved for its distinct texture and tangy flavor.
- Vegetarian
Toasted Ravioli
Crisp, breaded ravioli said to be born on The Hill, usually served with marinara. It is a signature St. Louis Italian-American appetizer.
- Vegetarian
Gooey Butter Cake
Sticky butter cake with a dense base and gooey sweet top. A longtime St. Louis bakery favorite often enjoyed for breakfast or dessert.
Bulrush
Refined contemporary restaurant with tasting menus and strong national acclaim. Elegant fine dining focused on seasonal Midwestern ingredients.
Ted Drewes Frozen Custard
Beloved frozen custard stand serving concretes and sundaes since 1929. Casual, nostalgic, and one of the city's iconic dessert stops.
Pappy's Smokehouse
Popular smokehouse known for St. Louis barbecue, especially ribs, brisket, and pork steak, in a polished but relaxed atmosphere.
United States dollar ($)
Moderate for U.S. city breaks: hotels and dining are reasonable, transit is limited, and attractions often cost less than in larger U.S. tourist cities.
Average meal costs
- Budget
- $10-15 for fast food or casual lunch.
- Mid-range
- $20-35 per person for a mid-range restaurant meal.
- Fine dining
- $60+ per person at upscale restaurants.
- Coffee
- $3-5 for coffee or cappuccino.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, and 10-15% for taxis. Cafes often have tip jars or screen prompts.
FAQs: Bus from Independence, MO to St. Louis, MO
Find answers to the most common questions about traveling from Independence, MO to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Independence, MO to St. Louis, MO can start from as little as $44 when you book in advance. The average bus ticket price for Independence, MO to St. Louis, MO is $71 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Independence, MO to St. Louis, MO is 4h 0m to travel the 229 miles (369 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Independence, MO to St. Louis, MO leaves at 1:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Independence, MO to St. Louis, MO leaves at 6:50 PM.
Yes, there are 4 direct buses a day from Independence, MO to St. Louis, MO with Greyhound. Schedules can vary on holidays or weekends with fewer direct buses.
When taking a bus from Independence, MO to St. Louis, MO, you can count on Greyhound for the best way to get you to St. Louis, MO. You can also check all possible bus companies who offer a service between Independence, MO and St. Louis, MO and compare the amenities they offer before buying a bus ticket.
When departing from Independence, MO , you have various bus station options to start your journey from including Kansas City, Jefferson Lines, Kansas City, 47th St (Transit Center), KS . When arriving in St. Louis, MO , you can end your journey in bus stations like St. Louis, S 15th St (Civic center) .Passengers board the bus most frequently from Kansas City, Jefferson Lines, which is located around away from the city centre, and they get off the bus at St. Louis, S 15th St (Civic center), located 0 away from the city centre.
A trip to St. Louis, MO from Independence, MO is worth doing but not as a day trip with a journey time of 4h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Independence, MO to St. Louis, MO is February.
It's helpful to compare your options as there are 2 ways to travel between Independence, MO and St. Louis, MO including taking a train and bus.
Yes, the following accessibility options are available when taking the bus from Independence, MO to St. Louis, MO:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Independence, MO to St. Louis, MO for bus company Greyhound.
Whether you can cancel your bus ticket from Independence, MO to St. Louis, MO depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Yes, bikes are allowed on board the bus with bus company Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Independence, MO to St. Louis, MO.
Yes, the following luggage options are included when booking a bus ticket from Independence, MO to St. Louis, MO:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Yes, the following additional luggage options are available when booking a bus ticket from Independence, MO to St. Louis, MO:
- Greyhound
- $15 per additional bag.
Unfortunately, pets are not allowed on the bus from Independence, MO to St. Louis, MO.
You can reserve your seat on the bus from Independence, MO to St. Louis, MO with the following bus company: Greyhound
Yes, there are USB plugs on board the bus from Independence, MO to St. Louis, MO with the following bus company: Greyhound.
Yes, there is Wifi on board the bus from Independence, MO to St. Louis, MO with the following bus company: Greyhound.
Since neither Independence, MO nor St. Louis, MO are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Independence, MO to St. Louis, MO among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In St. Louis, MO, travelers should be cautious in certain neighborhoods with higher crime rates, especially after dark. Common safety concerns include petty theft, pickpocketing, and occasional scams targeting visitors near popular attractions like the Gateway Arch. It’s advisable to stay in well-populated areas, avoid displaying valuables openly, and use reputable transportation services to minimize risks.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Independence, MO to St. Louis, MO
Most Independence, MO to St. Louis, MO buses use the Kansas City, Jefferson Lines to St. Louis, S 15th St (Civic center) station pair. Use this guide to compare Independence, MO and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Independence
Arrival bus stations in St. Louis
Which St. Louis, MO station do buses from Independence, MO arrive at?
Buses from Independence, MO to St. Louis, MO arrive at St. Louis, S 15th St (Civic center). St. Louis, S 15th St (Civic center) is 0 miles (1 km) from St. Louis, MO city centre.
St. Louis, S 15th St (Civic center)S 15th St, St. Louis, MO, USA
City-centre transport
Getting to St. Louis, S 15th St (Civic center) from St. Louis city centre
TrainMlb, Mlr · 4m · $4 · every ~14 min
Bus19, 32, 40 · 8m · $1 · every ~9 min
St. Louis, S 15th St (Civic center) bus station facilities and services
St. Louis, S 15th St (Civic center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at St. Louis, S 15th St (Civic center). ATMs are available at St. Louis, S 15th St (Civic center).
Tickets and information
Ticket office support is available at St. Louis, S 15th St (Civic center).
Parking, taxis and toilets
Available at St. Louis, S 15th St (Civic center): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at St. Louis, S 15th St (Civic center): Wheelchair accessible routes available.
More options for your journey from Independence, MO to St. Louis, MO
Here are some other resources that might have the information you need
Most popular buses to and from St. Louis, MO and Independence, MO
Most popular bus connections to St. Louis, MO
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