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Journey information
Overview: Bus from Gainesville, FL to Charleston, SC
Buses from Gainesville, FL to Charleston, SC run on average 2 times per day, taking around 13h 15m. Cheap bus tickets for this journey start at $57 (€46) if you book in advance.
The earliest bus runs at 00:35, the last at 22:40. The fastest bus covers the 257 miles (415 km) distance in 13h 15m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 257 miles (415 km) |
Average bus duration 13h 15m |
Cheapest ticket price $57 (€46) |
Buses per day 2 |
Fastest bus 13h 15m |
First bus 00:35 |
Last bus 22:40 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
FAQs: Bus from Gainesville, FL to Charleston, SC
Find answers to the most common questions about traveling from Gainesville, FL to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

The first bus from Gainesville, FL to Charleston, SC leaves at 1: 55PM. Plan your trip with the Journey Planner from Omio.
The last bus from Gainesville, FL to Charleston, SC leaves at 10: 20PM.
A day trip to Charleston, SC from Gainesville, FL is worth doing with a journey time of min each way. Check with Omio app the best way to travel.
No, the bus from Gainesville, FL to Charleston, SC has no accessibility options.
No, there are no bathrooms on board the bus from Gainesville, FL to Charleston, SC.
No, bikes are not allowed on board the bus from Gainesville, FL to Charleston, SC.
To find the cheapest bus tickets for your trip from Gainesville, FL to Charleston, SC, follow these tips:
Start your search now and compare ticket prices to find the best deal!
Yes, there is food available to purchase on board the bus from Gainesville, FL to Charleston, SC.
No, luggage for the bus from Gainesville, FL to Charleston, SC needs to be booked in addition.
No, there are no additional luggage options for the bus from Gainesville, FL to Charleston, SC.
Unfortunately, pets are not allowed on the bus from Gainesville, FL to Charleston, SC.
No, there are no USB plugs on board the bus from Gainesville, FL to Charleston, SC.
No, there is no WiFi on board the bus from Gainesville, FL to Charleston, SC.
popular bus stations
Popular bus stations from Gainesville, FL to Charleston, SC
Gainesville
Charleston
The major bus station for departures in Gainesville is Gainesville, Rosa Parks Transfer station. Find all the information you need to know about services, amenities and connections at Gainesville, Rosa Parks Transfer station for your trip from Gainesville to Charleston.
Gainesville, Rosa Parks Transfer station
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Gainesville, NW 23rd St (North Walmart Supercenter)
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The major bus station for arrivals in Charleston is Charleston, Gaynor Avenue (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Charleston, Gaynor Avenue (Greyhound Bus Station) for your trip to Charleston from Gainesville.
Charleston, Gaynor Avenue (Greyhound Bus Station)
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Most popular bus connections from Gainesville, FL
More options for your journey from Gainesville, FL to Charleston, SC
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