Journey information
Overview: Bus from Gainesville, FL to Charleston, SC
Buses from Gainesville, FL to Charleston, SC run on average 2 times per day, taking around 13h 15m. Cheap bus tickets for this journey start at $58 (€46) if you book in advance.
The earliest bus runs at 00:35, the last at 22:40. The fastest bus covers the 257 miles (415 km) distance in 13h 15m.
Distance 257 miles (415 km) |
Average bus duration 13h 15m |
Cheapest ticket price $58 (€46) |
Buses per day 2 |
Fastest bus 13h 15m |
First bus 00:35 |
Last bus 22:40 |
FAQs: Bus from Gainesville, FL to Charleston, SC
Find answers to the most common questions about traveling from Gainesville, FL to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

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Popular bus stations from Gainesville, FL to Charleston, SC
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