1,000+ travel companies
1,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
Compare prices and tickets Gainesville, FL to Key West, FL by bus
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sun
Dec 21
Dec 21
Mon
Dec 22
Dec 22
Tue
Dec 23
Dec 23
Wed
Dec 24
Dec 24
Thu
Dec 25
Dec 25
Fri
Dec 26
Dec 26
Sat
Dec 27
Dec 27
Journey information
Overview: Bus from Gainesville, FL to Key West, FL
USAUSA
Buses from Gainesville, FL to Key West, FL run on average 4 times per day, taking around 21h 17m. Cheap bus tickets for this journey start at $161 (€129) if you book in advance.
The earliest bus runs at 08:50, the last at 17:35. The fastest bus covers the 353 miles (569 km) distance in 18h 5m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 353 miles (569 km) |
Average bus duration 21h 17m |
Cheapest ticket price $161 (€129) |
Buses per day 4 |
Fastest bus 18h 5m |
First bus 08:50 |
Last bus 17:35 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: FlixBus from Gainesville, FL to Key West, FLYou can travel by bus between Gainesville, FL to Key West, FL with FlixBus for as low as $161 (€129). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
18h 5m
Cheapest Price
$160 (€128)
FlixBus frequency
4 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
FAQs: Bus from Gainesville, FL to Key West, FL
Find answers to the most common questions about traveling from Gainesville, FL to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Gainesville, FL to Key West, FL can start from as little as $182 (€146) when you book in advance. The average bus ticket price for Gainesville, FL to Key West, FL is $226 (€182); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Gainesville, FL to Key West, FL bus travel time is 18 h 5 min for the 353 mile (569 km) long route, but the duration can vary if you travel on weekends and holidays.
The first bus from Gainesville, FL to Key West, FL leaves at 9: 30AM. Plan your trip with the Journey Planner from Omio.
The last bus from Gainesville, FL to Key West, FL leaves at 5: 00PM.
There are 6 buses a day from Gainesville, FL to Key West, FL which require at least one change with FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Gainesville, FL to Key West, FL, you can count on FlixBus for the best way to get you to Key West, FL. You can also check all possible bus companies who offer a service between Gainesville, FL and Key West, FL and compare the amenities they offer before buying a bus ticket.
Yes, you can take a bus between Gainesville, FL and Key West, FL.
Yes, the following accessibility options are available when taking the bus from Gainesville, FL to Key West, FL:
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Gainesville, FL to Key West, FL for bus company FlixBus.
Some of the most interesting sights to explore in Key West, FL are:
- Ernest Hemingway Home and Museum, the former residence of the famous author featuring guided tours and a colony of six-toed cats
- Key West Butterfly and Nature Conservatory, a lush habitat housing hundreds of butterflies and exotic birds
- Fort Zachary Taylor Historic State Park, a Civil War-era fort offering beach access, snorkeling, and picnic areas
- Mallory Square, a waterfront plaza known for its nightly sunset celebrations and street performances
- Key West Lighthouse and Keeper's Quarters Museum, offering panoramic views of the island and insights into maritime history.
The best things to do in Key West, FL include:
- Duval Street, stroll along the vibrant street lined with shops, bars, and restaurants
- Dry Tortugas National Park, visit the remote park known for its historic fort and snorkeling opportunities
- Southernmost Point Buoy, take a photo at the iconic landmark marking the southernmost point in the continental USA
- Key West Ghost and Mysteries Tour, embark on a guided tour exploring the haunted history of the island
- Fury Water Adventures, enjoy a variety of water sports including snorkeling, parasailing, and sunset cruises.
Yes, bikes are allowed on board the bus with bus company FlixBus.
Whether you can cancel your bus ticket from Gainesville, FL to Key West, FL depends on the bus company:
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
To find the cheapest bus tickets for your trip from Gainesville, FL to Key West, FL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
Yes, there is food available to purchase on board the bus from Gainesville, FL to Key West, FL.
Yes, the following luggage options are included when booking a bus ticket from Gainesville, FL to Key West, FL:
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Gainesville, FL to Key West, FL:
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Gainesville, FL to Key West, FL. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- Guide dogs travel for free.
You can reserve your seat on the bus from Gainesville, FL to Key West, FL with the following bus company: FlixBus
Yes, there are USB plugs on board the bus from Gainesville, FL to Key West, FL with the following bus company: FlixBus.
Yes, there is Wifi on board the bus from Gainesville, FL to Key West, FL with the following bus company: FlixBus.
popular bus stations
Popular bus stations from Gainesville, FL to Key West, FL
Gainesville
Key West
The major bus station for departures in Gainesville is Gainesville, Rosa Parks Transfer station. Find all the information you need to know about services, amenities and connections at Gainesville, Rosa Parks Transfer station for your trip from Gainesville to Key West.
Gainesville, Rosa Parks Transfer station
information
Gainesville, NW 23rd St (North Walmart Supercenter)
information
The major bus station for arrivals in Key West is Key West, South Roosevelt Boulevard (Key West International Airport). Find all the information you need to know about services, amenities and connections at Key West, South Roosevelt Boulevard (Key West International Airport) for your trip to Key West from Gainesville.
Key West, South Roosevelt Boulevard (Key West International Airport)
information
Most popular bus connections from Gainesville, FL
More options for your journey from Gainesville, FL to Key West, FL
Here are some other resources that might have the information you need
Most popular buses to and from Key West, FL and Gainesville, FL
Most popular bus connections to Key West, FL
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
