The cheapest and fastest buses from Gainesville, FL to Key West, FL
Cheapest price
$102
Average price
$111
Fastest journey
14 h 55 m
Average duration
19 h 50 m
Buses per day
5
Distance
569 km
The best way to find a cheap bus ticket from Gainesville, FL to Key West, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Gainesville, FL to Key West, FL will cost around $111 if you buy it on the day, but the cheapest tickets can be found for only $102.
It's difficult to get from Gainesville, FL to Key West, FL without transferring at least once.
FlixBus+
· 6:05 PM15h25Gainesville, Rosa Parks Transfer station9:30 AMKey West, South Roosevelt Boulevard (Key West International Airport), FL$1021One-way2 transfers
· 12:35 AM14h55Gainesville, NW 23rd St (North Walmart Supercenter), FL3:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FL$1051One-way1 transfer
· +
FlixBus+
8:00 AM25h30Gainesville, NW 23rd St (North Walmart Supercenter), FL9:30 AMKey West, South Roosevelt Boulevard (Key West International Airport), FL$1121One-way4 transfers
FlixBus · FlixBus+
9:20 PM15h10Gainesville, Rosa Parks Transfer station12:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FL$1161One-way2 transfers
FlixBus · FlixBus+
· 8:20 AM28h10Gainesville, NW 23rd St (North Walmart Supercenter), FL12:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FL$1181One-way4 transfers
· 12:35 AM14h55Gainesville, NW 23rd St (North Walmart Supercenter), FL3:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FL$1051One-way1 transfer
FlixBus · FlixBus+
9:20 PM15h10Gainesville, Rosa Parks Transfer station12:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FL$1161One-way2 transfers
FlixBus+
· 6:05 PM15h25Gainesville, Rosa Parks Transfer station9:30 AMKey West, South Roosevelt Boulevard (Key West International Airport), FL$1021One-way2 transfers
· +
FlixBus+
8:00 AM25h30Gainesville, NW 23rd St (North Walmart Supercenter), FL9:30 AMKey West, South Roosevelt Boulevard (Key West International Airport), FL$1121One-way4 transfers
FlixBus · FlixBus+
· 8:20 AM28h10Gainesville, NW 23rd St (North Walmart Supercenter), FL12:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FL$1181One-way4 transfers
Gainesville, FL to Key West, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:35AM | Arrival Time 03:30PM | Duration 14h55 | Departure days Mon, Sun | Cheapest price $85 |
Operator Greyhound | Departure Time 08:00AM | Arrival Time 09:30AM | Duration 25h30 | Departure days Mon, Sun | Cheapest price $92 |
Operator FlixBus | Departure Time 08:20AM | Arrival Time 12:30PM | Duration 28h10 | Departure days Mon, Sun | Cheapest price $93 |
Operator Greyhound | Departure Time 06:05PM | Arrival Time 09:30AM | Duration 15h25 | Departure days Mon, Sun | Cheapest price $84 |
Operator FlixBus | Departure Time 09:20PM | Arrival Time 12:30PM | Duration 15h10 | Departure days Mon, Sun | Cheapest price $84 |
Live departures
Gainesville, FL to Key West, FL bus times
The table below shows live departures for Gainesville, FL to Key West, FL buses for tomorrow, Sunday, August 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 12:35 AM Gainesville, NW 23rd St (North Walmart Supercenter), FL | 14h55 | 3:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL | 1 transfer | |
· + FlixBus+![]() | 8:00 AM Gainesville, NW 23rd St (North Walmart Supercenter), FL | 25h30 | 9:30 AM Key West, South Roosevelt Boulevard (Key West International Airport), FL | 4 transfers | |
FlixBus · FlixBus+ · | 8:20 AM Gainesville, NW 23rd St (North Walmart Supercenter), FL | 28h10 | 12:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL | 4 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Journey information
Overview: Bus from Gainesville, FL to Key West, FL
Take a bus from Gainesville, FL to Key West, FL and enjoy the approximately 353 miles (569 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 10:00, the last at 17:00.
Distance 353 miles (569 km) |
Buses per day 5 |
First bus 10:00 AM |
Last bus 5:00 PM |
Cheapest Month Jan |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
FAQs: Bus from Gainesville, FL to Key West, FL
Find answers to the most common questions about traveling from Gainesville, FL to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.

- Ernest Hemingway Home and Museum, the former residence of the famous author featuring guided tours and a colony of six-toed cats
- Key West Butterfly and Nature Conservatory, a lush habitat housing hundreds of butterflies and exotic birds
- Fort Zachary Taylor Historic State Park, a Civil War-era fort offering beach access, snorkeling, and picnic areas
- Mallory Square, a waterfront plaza known for its nightly sunset celebrations and street performances
- Key West Lighthouse and Keeper's Quarters Museum, offering panoramic views of the island and insights into maritime history.
- Duval Street, stroll along the vibrant street lined with shops, bars, and restaurants
- Dry Tortugas National Park, visit the remote park known for its historic fort and snorkeling opportunities
- Southernmost Point Buoy, take a photo at the iconic landmark marking the southernmost point in the continental USA
- Key West Ghost and Mysteries Tour, embark on a guided tour exploring the haunted history of the island
- Fury Water Adventures, enjoy a variety of water sports including snorkeling, parasailing, and sunset cruises.
popular bus stations
Popular bus stations from Gainesville, FL to Key West, FL
Most Gainesville, FL to Key West, FL buses use the Gainesville, NW 23rd St (North Walmart Supercenter) to Key West, South Roosevelt Boulevard (Key West International Airport) station pair. Use this guide to compare Gainesville, FL and Key West, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Gainesville, FL station do buses to Key West, FL leave from?
Getting to Gainesville, NW 23rd St (North Walmart Supercenter) from Gainesville city centre
Gainesville, NW 23rd St (North Walmart Supercenter) is 7 km from Gainesville city centre. Public transport options include:
Gainesville, NW 23rd St (North Walmart Supercenter) bus station facilities and services
Gainesville, NW 23rd St (North Walmart Supercenter) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Gainesville, NW 23rd St (North Walmart Supercenter). ATMs are available at Gainesville, NW 23rd St (North Walmart Supercenter).
Tickets and information
Ticket office support is available at Gainesville, NW 23rd St (North Walmart Supercenter).
Parking, taxis and toilets
Available at Gainesville, NW 23rd St (North Walmart Supercenter): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Gainesville, NW 23rd St (North Walmart Supercenter): Bus stop has basic accessibility features.
Getting to Gainesville, Rosa Parks Transfer station from Gainesville city centre
Gainesville, Rosa Parks Transfer station bus station facilities and services
Gainesville, Rosa Parks Transfer station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free Wi-Fi is available at the station. ATMs are available at Gainesville, Rosa Parks Transfer station.
Tickets and information
Ticket office support is available at Gainesville, Rosa Parks Transfer station.
Parking, taxis and toilets
Available at Gainesville, Rosa Parks Transfer station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Gainesville, Rosa Parks Transfer station: The station is wheelchair accessible.
Which Key West, FL station do buses from Gainesville, FL arrive at?
Getting to Key West, South Roosevelt Boulevard (Key West International Airport) from Key West city centre
Key West, South Roosevelt Boulevard (Key West International Airport) is 2 km from Key West city centre. Public transport options include:
Key West, South Roosevelt Boulevard (Key West International Airport) bus station facilities and services
Key West, South Roosevelt Boulevard (Key West International Airport) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Key West, South Roosevelt Boulevard (Key West International Airport). ATMs are available at Key West, South Roosevelt Boulevard (Key West International Airport).
Tickets and information
Ticket office support is available at Key West, South Roosevelt Boulevard (Key West International Airport).
Parking, taxis and toilets
Available at Key West, South Roosevelt Boulevard (Key West International Airport): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Key West, South Roosevelt Boulevard (Key West International Airport): The station is wheelchair accessible.
Most popular bus connections from Gainesville, FL
More options for your journey from Gainesville, FL to Key West, FL
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