- Must visit
Ernest Hemingway Home and Museum
The Ernest Hemingway Home and Museum lets visitors tour the writer's residence, gardens, and rooms tied to his Key West years.
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Why should you book Gainesville, FL to Key West, FL buses with Omio?
Greyhound as well as FlixBus offer buses services from Gainesville, FL to Key West, FL.
Omio is an official ticket reseller for all your travel options from Gainesville, FL to Key West, FL.
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Gainesville, FL to Key West, FL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Gainesville, FL to Key West, FL.
Journey information
Overview: Bus from Gainesville, FL to Key West, FL
USAUSA
Buses from Gainesville, FL to Key West, FL run on average 4 times per day, taking around 14h 22m. Cheap bus tickets for this journey start at $72 (€59) if you book in advance.
The earliest bus runs at 10:00, the last at 17:00. The fastest bus covers the 353 miles (569 km) distance in 11h 20m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 353 miles (569 km) |
Average bus duration 14h 22m |
Cheapest ticket price $72 (€59) |
Buses per day 4 |
Fastest bus 11h 20m |
First bus 10:00 AM |
Last bus 5:00 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: Greyhound, FlixBus from Gainesville, FL to Key West, FLYou can travel by bus between Gainesville, FL to Key West, FL with Greyhound, FlixBus for as low as $72 (€59). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
12h 29m
Cheapest FlixBus Price
$77 (€63)
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
11h 20m
Cheapest Greyhound Price
$72 (€59)
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Complete guide to Key West, FL
Things to do in Key West, FL
Discover the best of Key West, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Key West, FL trip today.
- Recommended
Key West Butterfly and Nature Conservatory
The Key West Butterfly and Nature Conservatory features a glass habitat with butterflies, birds, and tropical plants in a calm setting.
- Recommended
Key West Museum of Art and History at the Custom House
The Key West Museum of Art and History at the Custom House presents island history, art, and rotating exhibitions in a grand landmark building.
- Must visit
Duval Street
Duval Street is Key West's main historic thoroughfare, lined with shops, galleries, and lively architecture across the old town.
- Must visit
Mallory Square
Mallory Square is a waterfront plaza known for harbor views, public space, and easy access to the historic seaport district.
- Must visit
Fort Zachary Taylor Historic State Park
Fort Zachary Taylor Historic State Park combines a coastal fort, walking paths, shaded grounds, and one of the island's best natural beaches.
- Vegetarian
Key Lime Pie
Tangy pie made with Key lime juice, sweetened condensed milk, and a graham cracker crust. It is the island's signature dessert and a classic Florida Keys specialty.
- Gluten-free
Key West Pink Shrimp
Fresh local pink shrimp, usually simply peeled and chilled or lightly cooked. They are prized in the Keys for their sweet flavor and local waters.
- Gluten-free
Yellowtail Snapper
Whole snapper, often yellowtail, seasoned and grilled or baked. It reflects Key West's strong fishing culture and the abundance of fresh local catch.
Nine One Five
Polished seafood restaurant focused on Florida fish, oysters, and seasonal ingredients in a refined but approachable dining room.
Sandy's Cafe
Beloved casual spot for Cuban coffee, breakfast, sandwiches, and Cuban toast. A dependable choice for everyday local flavors.
Half Shell Raw Bar
Historic seafood house known for pink shrimp, conch dishes, and classic Key lime pie in a lively, casual Old Town setting.
US Dollar ($)
Very pricey versus many US beach towns; hotels, seafood, and drinks run high, while transit is limited and parking can add costs.
Average meal costs
- Budget
- $12-20 for fast food or casual takeout.
- Mid-range
- $25-45 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $4-6 for coffee or a latte.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and small change at cafes.
FAQs: Bus from Gainesville, FL to Key West, FL
Find answers to the most common questions about traveling from Gainesville, FL to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.
Cheap bus tickets from Gainesville, FL to Key West, FL can start from as little as $72 (€59) when you book in advance. The average bus ticket price for Gainesville, FL to Key West, FL is $92 (€76) ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Gainesville, FL to Key West, FL is 11h 20m to travel the 353 miles (569 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Gainesville, FL to Key West, FL leaves at 10:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Gainesville, FL to Key West, FL leaves at 5:00 PM.
There are 4 buses a day from Gainesville, FL to Key West, FL which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Gainesville, FL to Key West, FL, you can count on Greyhound, FlixBus for the best way to get you to Key West, FL. You can also check all possible bus companies who offer a service between Gainesville, FL and Key West, FL and compare the amenities they offer before buying a bus ticket.
When departing from Gainesville, FL , you have various bus station options to start your journey from including Gainesville, NW 23rd St (North Walmart Supercenter), FL, Gainesville, Rosa Parks Transfer station . When arriving in Key West, FL , you can end your journey in bus stations like Key West, South Roosevelt Boulevard (Key West International Airport), FL .Passengers board the bus most frequently from Gainesville, NW 23rd St (North Walmart Supercenter), FL, which is located around 4 miles (7 km) away from the city centre, and they get off the bus at Key West, South Roosevelt Boulevard (Key West International Airport), FL, located 2 away from the city centre.
Yes, you can take a bus between Gainesville, FL and Key West, FL.
Yes, the following accessibility options are available when taking the bus from Gainesville, FL to Key West, FL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Gainesville, FL to Key West, FL for bus company Greyhound, FlixBus.
Whether you can cancel your bus ticket from Gainesville, FL to Key West, FL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Gainesville, FL to Key West, FL.
Yes, the following luggage options are included when booking a bus ticket from Gainesville, FL to Key West, FL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Gainesville, FL to Key West, FL:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Gainesville, FL to Key West, FL. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Gainesville, FL to Key West, FL with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Gainesville, FL to Key West, FL with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Gainesville, FL to Key West, FL with the following bus company: Greyhound, FlixBus.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Key West, FL, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Duval Street. Common scams include overpriced taxi rides and timeshare presentations that pressure visitors into purchases. It's advisable to use licensed transportation and be vigilant with personal belongings to stay safe.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular bus stations
Popular bus stations from Gainesville, FL to Key West, FL
Most Gainesville, FL to Key West, FL buses use the Gainesville, NW 23rd St (North Walmart Supercenter) to Key West, South Roosevelt Boulevard (Key West International Airport) station pair. Use this guide to compare Gainesville, FL and Key West, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Gainesville
Arrival bus stations in Key West
Which Gainesville, FL station do buses to Key West, FL leave from?
Buses from Gainesville, FL to Key West, FL leave from Gainesville, NW 23rd St (North Walmart Supercenter). The station is 4 miles (7 km) from Gainesville, FL city centre at 5700 NW 23rd St, Gainesville, FL 32653, USA.
Gainesville, NW 23rd St (North Walmart Supercenter)5700 NW 23rd St, Gainesville, FL 32653, USA
City-centre transport
Getting to Gainesville, NW 23rd St (North Walmart Supercenter) from Gainesville city centre
Gainesville, NW 23rd St (North Walmart Supercenter) is 7 km from Gainesville city centre. Public transport options include:
Bus6 · 23m · every ~1 min
6 · 25m · every ~1 min
6 · 26m · every ~1 min
8 · 31m · every ~2 min
Gainesville, NW 23rd St (North Walmart Supercenter) bus station facilities and services
Gainesville, NW 23rd St (North Walmart Supercenter) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Gainesville, NW 23rd St (North Walmart Supercenter). ATMs are available at Gainesville, NW 23rd St (North Walmart Supercenter).
Tickets and information
Ticket office support is available at Gainesville, NW 23rd St (North Walmart Supercenter).
Parking, taxis and toilets
Available at Gainesville, NW 23rd St (North Walmart Supercenter): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Gainesville, NW 23rd St (North Walmart Supercenter): Bus stop has basic accessibility features.
Gainesville, Rosa Parks Transfer stationRosa Parks Transfer station, 700 SE 3rd St, Gainesville, FL 32601, USA
City-centre transport
Getting to Gainesville, Rosa Parks Transfer station from Gainesville city centre
Bus15, 6, 5, 46, 10, 1, 25 · 2m · every ~15 min
Gainesville, Rosa Parks Transfer station bus station facilities and services
Gainesville, Rosa Parks Transfer station has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Free Wi-Fi is available at the station. ATMs are available at Gainesville, Rosa Parks Transfer station.
Tickets and information
Ticket office support is available at Gainesville, Rosa Parks Transfer station.
Parking, taxis and toilets
Available at Gainesville, Rosa Parks Transfer station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Gainesville, Rosa Parks Transfer station: The station is wheelchair accessible.
Which Key West, FL station do buses from Gainesville, FL arrive at?
Buses from Gainesville, FL to Key West, FL arrive at Key West, South Roosevelt Boulevard (Key West International Airport). Key West, South Roosevelt Boulevard (Key West International Airport) is 1 miles (3 km) from Key West, FL city centre.
Key West, South Roosevelt Boulevard (Key West International Airport)Key West International Airport, 3491 S Roosevelt Blvd, Key West, FL 33040, USA
City-centre transport
Getting to Key West, South Roosevelt Boulevard (Key West International Airport) from Key West city centre
Key West, South Roosevelt Boulevard (Key West International Airport) is 2 km from Key West city centre. Public transport options include:
TRUE
Key West, South Roosevelt Boulevard (Key West International Airport) bus station facilities and services
Key West, South Roosevelt Boulevard (Key West International Airport) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Key West, South Roosevelt Boulevard (Key West International Airport). ATMs are available at Key West, South Roosevelt Boulevard (Key West International Airport).
Tickets and information
Ticket office support is available at Key West, South Roosevelt Boulevard (Key West International Airport).
Parking, taxis and toilets
Available at Key West, South Roosevelt Boulevard (Key West International Airport): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Key West, South Roosevelt Boulevard (Key West International Airport): The station is wheelchair accessible.
Most popular bus connections from Gainesville, FL
More options for your journey from Gainesville, FL to Key West, FL
Here are some other resources that might have the information you need
Most popular buses to and from Key West, FL and Gainesville, FL
Most popular bus connections to Key West, FL
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