Gainesville, FL to Key West, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:35AM | Arrival Time 03:30PM | Duration 14h55 | Departure days Thu, Sat | Cheapest price $101 |
Operator Greyhound | Departure Time 08:00AM | Arrival Time 09:30AM | Duration 25h30 | Departure days Thu, Sat | Cheapest price $104 |
Operator FlixBus | Departure Time 08:20AM | Arrival Time 12:30PM | Duration 28h10 | Departure days Thu, Sat | Cheapest price $107 |
Operator Greyhound | Departure Time 06:05PM | Arrival Time 09:30AM | Duration 15h25 | Departure days Thu, Sat | Cheapest price $93 |
Operator FlixBus | Departure Time 09:20PM | Arrival Time 12:30PM | Duration 15h10 | Departure days Thu, Sat | Cheapest price $102 |
Live departures
Gainesville, FL to Key West, FL bus times
The table below shows live departures for Gainesville, FL to Key West, FL buses for today, Saturday, June 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+ · | 6:05 PM Gainesville, Rosa Parks Transfer station | 15h25 | 9:30 AM Key West, South Roosevelt Boulevard (Key West International Airport), FL | 2 transfers | |
FlixBus · FlixBus+![]() | 9:20 PM Gainesville, Rosa Parks Transfer station | 15h10 | 12:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL | 2 transfers | |
This is the last bus of the day. | |||||
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Journey information
Overview: Bus from Gainesville, FL to Key West, FL
Take a bus from Gainesville, FL to Key West, FL and enjoy the approximately 353 miles (569 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest bus runs at 10:00, the last at 17:00.
Distance 353 miles (569 km) |
Buses per day 5 |
First bus 10:00 AM |
Last bus 5:00 PM |
Cheapest Month Jan |
Cheapest Day Sun |
High Season Jan - Mar |
Low Season Jul - Sep |
FAQs: Bus from Gainesville, FL to Key West, FL
Find answers to the most common questions about traveling from Gainesville, FL to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.

- Ernest Hemingway Home and Museum, the former residence of the famous author featuring guided tours and a colony of six-toed cats
- Key West Butterfly and Nature Conservatory, a lush habitat housing hundreds of butterflies and exotic birds
- Fort Zachary Taylor Historic State Park, a Civil War-era fort offering beach access, snorkeling, and picnic areas
- Mallory Square, a waterfront plaza known for its nightly sunset celebrations and street performances
- Key West Lighthouse and Keeper's Quarters Museum, offering panoramic views of the island and insights into maritime history.
- Duval Street, stroll along the vibrant street lined with shops, bars, and restaurants
- Dry Tortugas National Park, visit the remote park known for its historic fort and snorkeling opportunities
- Southernmost Point Buoy, take a photo at the iconic landmark marking the southernmost point in the continental USA
- Key West Ghost and Mysteries Tour, embark on a guided tour exploring the haunted history of the island
- Fury Water Adventures, enjoy a variety of water sports including snorkeling, parasailing, and sunset cruises.
popular bus stations
Popular bus stations from Gainesville, FL to Key West, FL
Most Gainesville, FL to Key West, FL buses use the Gainesville, Rosa Parks Transfer station to Key West, South Roosevelt Boulevard (Key West International Airport) station pair. Use this guide to compare Gainesville, FL and Key West, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to Gainesville, Rosa Parks Transfer station from Gainesville city centre
Getting to Gainesville, NW 23rd St (North Walmart Supercenter) from Gainesville city centre
Most popular bus connections from Gainesville, FL
More options for your journey from Gainesville, FL to Key West, FL
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