- Must visit
National Museum of Civil War Medicine
Interactive museum explaining battlefield medicine, surgery, and care during the Civil War in a historic downtown building.
Cheapest price on Oct 29
$51
Average ticket price on Oct 29
$52
Fastest journey on Oct 29
5 h 25 m
Average journey duration on Oct 29
6 h 30 m
Buses on Oct 29
2
Distance
201 km
The best way to find a cheap bus ticket from Philadelphia, PA to Frederick, MD is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Philadelphia, PA to Frederick, MD will cost around $52 if you buy it on the day, but the cheapest tickets can be found for only $51.
It's difficult to get from Philadelphia, PA to Frederick, MD without transferring at least once.
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Buses from Philadelphia, PA to Frederick, MD run on average 3 times per day, taking around 4h 48m. Cheap bus tickets for this journey start at $41 (€35) if you book in advance.
The earliest bus runs at 00:30, the last at 23:15. The fastest bus covers the 124 miles (201 km) distance in 4h 0m.
Plan this route
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Philadelphia, PA to Frederick, MD.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:30AM | Arrival Time 10:40AM | Duration 10h10 | Departure days Thu | Cheapest price $61 |
Operator FlixBus | Departure Time 02:00AM | Arrival Time 10:40AM | Duration 8h40 | Departure days Wed | Cheapest price $58 |
Operator FlixBus | Departure Time 03:05AM | Arrival Time 08:30AM | Duration 5h25 | Departure days Thu, Fri | Cheapest price $51 |
Operator Greyhound | Departure Time 11:55AM | Arrival Time 07:30PM | Duration 7h35 | Departure days Thu, Fri | Cheapest price $52 |
Operator Greyhound | Departure Time 01:45PM | Arrival Time 11:25PM | Duration 9h40 | Departure days Tue, Wed, Sat | Cheapest price $40 |
Operator Greyhound | Departure Time 02:45PM | Arrival Time 12:25AM | Duration 9h40 | Departure days Tue | Cheapest price $48 |
Operator FlixBus | Departure Time 03:15PM | Arrival Time 12:25AM | Duration 9h10 | Departure days Sat | Cheapest price $50 |
The table below shows live departures for Philadelphia, PA to Frederick, MD buses for tomorrow, Thursday, October 29. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus+![]() | 3:05 AM Philadelphia Bus Station | 5h25 | 8:30 AM Frederick, East Street (Transit Center) | 1 transfer | |
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Find all the dates and times for this journey
Buses from Philadelphia, PA to Frederick, MD with Greyhound and FlixBus. Overnight buses available on this route with Greyhound and FlixBus. Use the details below to compare onboard facilities.
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Frederick, MD — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Frederick, MD trip today.
Interactive museum explaining battlefield medicine, surgery, and care during the Civil War in a historic downtown building.
Regional history museum with exhibits on Frederick County life, culture, and changing communities inside a restored historic home.
Contemporary art space in downtown Frederick presenting rotating exhibitions by regional and national artists in a modern gallery setting.
Linear downtown park and promenade with fountains, public art, bridges, and event spaces, ideal for walking day or evening.
Central historic district with preserved architecture, local shops, galleries, and easy access to many of Frederick’s main sights.
Popular downtown street lined with historic buildings, boutiques, public art, and one of the city’s best pedestrian atmospheres.
Maryland crab cakes are packed with blue crab and light seasoning. They are a regional staple near Frederick and widely served across Central Maryland.
Cream of crab soup is a rich Maryland favorite made with crab meat, cream, and seasoning. It reflects the state's strong Chesapeake seafood tradition.
Smith Island cake is Maryland's official state dessert, with many thin cake layers and frosting. It is a classic sweet treat found around Frederick.
Well-known farm brewery outside downtown with estate beer, pizza, and scenic grounds suited to relaxed afternoons.
Contemporary American restaurant known for wood-fired dishes, cocktails, and a polished but relaxed downtown atmosphere.
Casual local favorite for New York-style pizza, pasta, and Italian-American comfort food in the historic district.
Moderate for a U.S. mid-size city: hotels and dining are below major metros, but car-based transport and limited transit can raise visitor costs.
Tip 18-20% at restaurants, more for excellent service. Taxis usually 10-15%. Cafes often have tip jars; $1-2 is common.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Frederick, MD.
Find answers to the most common questions about traveling from Philadelphia, PA to Frederick, MD by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Frederick, MD, this guide helps you travel smarter and with confidence.

Most Philadelphia, PA to Frederick, MD buses use the Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) to Frederick, East Street (Transit Center) station pair. Use this guide to compare Philadelphia, PA and Frederick, MD bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) is 2 km from Philadelphia city centre. Public transport options include:
Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park). ATMs are available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park).
Ticket office support is available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park).
Available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park): Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Spring Garden St / N 2nd St (Madison War Memorial Park): The bus stop is accessible with ramps.
Philadelphia, Greyhound Bus Station has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Snack bars and vending machines are available.
Free Wi-Fi available in the waiting area. ATMs are an ATM is available near the entrance.
Ticket office support is available at Philadelphia, Greyhound Bus Station.
Available at Philadelphia, Greyhound Bus Station: Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Greyhound Bus Station: The station is wheelchair accessible with ramps and elevators.
Philadelphia, Schuylkill Ave (Cira Centre South) is 1 km from Philadelphia city centre. Public transport options include:
Philadelphia, Schuylkill Ave (Cira Centre South) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Free Wi-Fi available in the waiting area. ATMs are available at Philadelphia, Schuylkill Ave (Cira Centre South).
Ticket office support is available at Philadelphia, Schuylkill Ave (Cira Centre South).
Available at Philadelphia, Schuylkill Ave (Cira Centre South): Parking, Taxis, WC.
Accessibility facilities are available at Philadelphia, Schuylkill Ave (Cira Centre South): Wheelchair accessible area.
Frederick, East Street (Transit Center) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Frederick, East Street (Transit Center). ATMs are available at Frederick, East Street (Transit Center).
Ticket office support is available at Frederick, East Street (Transit Center).
Available at Frederick, East Street (Transit Center): Parking, Taxis, WC.
Accessibility facilities are available at Frederick, East Street (Transit Center): Wheelchair accessible entry and exit points.
Check bus stations information for Philadelphia, PA and Frederick, MD, including where buses depart and arrive on this route.