Travel Information
Compare train, bus, and flight for Brussels to Prague
Omio recommends booking the flight as it is the most popular option from Brussels to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $51. For those with little time consider booking a flight which can get you there in 2h 6m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of $51, and a flight costs an average of $25.
Distance: 445 miles (717 km)
Compare flight with
Most popular Flight | Train | Bus |
|---|---|---|
$146 Average price | $145 Average price | $83 Average price Cheapest |
5h 6m Average total duration Fastest 2h 6m Onboard + 3h 0m Additional time* | 13h 15m Average total duration 12h 45m Onboard + 30m Additional time* | 15h 58m Average total duration 15h 28m Onboard + 30m Additional time* |
2.2 - 4.3kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | 0.7 - 1.8kg CO2 emissions |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Brussels to Prague
How to get from Brussels to Prague by train, bus or flight.
Our recommendation
The best way to travel from Brussels to Prague is by taking a flight because it’s the best combination of price and speed.
QS1003Cheapest
(London -> Prague)Fastest
QS1003Other options
ICE 13 · ICE 547 · rj 177
ICE 15 · ICE 549 · rj 385
ICE 13 · ICE 547 · RJ 177
(London -> Prague)
FlixBus
FlixBus · FlixBus
SK1594 · SK1761
KL1704+
KL1355
9315+
U27929Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 25
Feb 26
Feb 27
Feb 28
Mar 01
Mar 02
Mar 03
Mar 04
Mar 05
Mar 06
Mar 07
Mar 08
Mar 09
Mar 10
Mar 11
Mar 12
Mar 13
Mar 14
Mar 15
Mar 16
Mar 17
How to Travel from Brussels to Prague?
As you plan your trip Brussels to Prague, you will find that there are three convenient modes of transportation that you may choose from. The three ways to travel to Prague from Brussels are by bus, by train and by plane. There are around 20 buses that depart daily, and take a little over 15 hours on average to arrive at the destination. Three trains serve this route daily, with a journey time of fewer than 10 hours. Lastly, around 25 flights travel from Brussels to Prague each day, with a flight time of 1 hour and 30 minutes.
What is the Cheapest Way To Get from Brussels to Prague?
The cheapest mode of transportation, if booked at least a month or a few weeks in advance, is by taking the plane. Nonetheless, all three methods of transportation can be relatively cheap if booked ahead of the departure date.
What is the Fastest Way to Travel from Brussels to Prague?
The fastest mode of transportation to travel from Brussels to Prague is definitely by plane. By choosing to fly to Prague, you will be able to arrive at your final destination in just one and a half hours. These flights usually depart from either the Brussels Airport (BRU) or the Brussels South Charleroi Airport (CRL) and arrive at the Prague Vaclav Havel Airport (PRG). All of these airports are near the city center.
Find and Book with Omio the Best Tickets from Brussels to Prague
The services provided by the Omio app and website will give you the necessary tools to book any tickets for any mode of transport from Brussels to Prague.
Travel from Brussels to Prague by Bus
Traveling by bus is a great way for you to experience the scenery on the route from Brussels to Prague. You will be able to choose between several departure stations in Brussels, including Brussels South (Gare du Midi), Brussels - Nord and Brussels - Gare du Midi. Travelers will arrive into one of the two main stations in Prague, including Úan Florenc and Hlavní Nádrazí. The average journey takes 15 hours and 27 minutes, with routes either being direct or with up to 4 transfers. The main bus operators for this route are Deutsche Bahn, RegioJet, Eurolines, and FlixBus.
Travel from Brussels to Prague by Train
Another mode of transportation servicing the route from Brussels to Prague is by train. Traveling by train is the second fastest and second most affordable mode of transport. The average journey takes on average 13 hours, and requires between two and four transfers. Only around three trains are scheduled daily and, therefore, it is best to book the tickets ahead of time. The trains usually depart from Brussels-Nord and arrive at Praha Hlavaní Nádrazí station. The train routes are serviced by Deutsche Bahn.
Travel from Brussels to Prague by Plane
The fastest and most affordable mode of transportation to travel from Prague to Amsterdam is by taking the plane. You will find that more than 20 planes depart daily from Brussels Airport (BRU) and Brussels South Charleroi Airport (CRL), and arrive into the Prague Vaclav Havel Airport (PRG). Planes are usually direct on this route and last only an hour and 30 minutes. The flights are operated by RyanAir, Czech Airlines, LOT, KLM, Alitalia, Lufthansa, Austrian Airlines and Air France.
How to get from Brussels to Prague
The Best Way According to our Users
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Brussels to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Brussels to Prague.

This is compared to other travel options from Brussels to Prague:
A flight is $6 (€5) less than a train for this route with tickets for a train from Brussels to Prague costing on average $31 (€25).
A flight is $28 (€22) less than a bus for this route with tickets for a bus from Brussels to Prague costing on average $53 (€42).
Other travel options to Prague take longer:
Train takes on average 10h 41m.
Bus takes on average 11h 50m.
- Around 42 flights per day.
- Around 18 buses per day.
- Around 6 trains per day.
However, we recommend checking specific travel dates for your route between Brussels and Prague as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Brussels Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Brussels-Midi and arrive in Prague hlavní nádraží.
- Buses mostly depart from Brussels, Brussels South (Gare du Midi) and arrive in Praha, ÚAN Florenc.
- Travel with FlixBus, BlaBlaCar Bus, Infobus to go to Prague by bus.
- Travel with Brussels Airlines, Ryanair, Smartwings, Buzz, KLM Cityhopper, LOT Polish Airlines, Lufthansa, SAS, KLM, CityJet, Air Baltic, LAER, Lufthansa Cityline, SWISS, Austrian Airlines to go to Prague by flight.
- Travel with Deutsche Bahn, European Sleeper, České dráhy, Alex, European Sleeper to go to Prague by train.
- 2 direct buses per day with FlixBus, Infobus.
- 4 direct flights per day with Brussels Airlines, Ryanair, Buzz.
- 0 direct trains per day with European Sleeper.
Travelling from Brussels to Prague: related information
Here are some other resources that might have the information you need

