Travel Information
Compare train, bus, and flight for Brussels to Prague
Omio recommends booking the flight as it is the most popular option from Brussels to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $80 For those with little time, consider booking a flight, which has an average total journey time of 4h 56m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.6kg. Average ticket prices depend on the travel mode: a bus costs an average of $80, while a flight costs an average of $356.
Distance: 445 miles (717 km)
Compare flight with
Most popular Flight | Train | Bus | Driving |
|---|---|---|---|
$356 Average price | $200 Average price | $80 Average price Cheapest | $179 Average price (fuel + tolls) |
4h 56m Average total duration Fastest 2h 56m Onboard + 2h 0m Additional time* | 11h 15m Average total duration 10h 45m Onboard + 30m Additional time* | 16h 18m Average total duration 15h 48m Onboard + 30m Additional time* | 8h 38m Average total duration (door-to-door) |
2.2 - 4.3kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | 0.7 - 1.8kg CO2 emissions | - CO2 emissions |
![]() Most popular airline | ![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Brussels to Prague:
A bus is $120 (€100) less than a train for this route with tickets for a train from Brussels to Prague costing on average $200 (€167).
A bus is $276 (€231) less than a flight for this route with tickets for a flight from Brussels to Prague costing on average $356 (€298).
Other travel options to Prague take longer:
Train takes on average 11h 15m.
Bus takes on average 16h 18m.
You'll arrive about 5h 42m sooner (2h 56m by flight vs 8h 38m by car). Tickets start at around $356 (€298) compared to roughly $179 (€150) in fuel and tolls — a bit more, but you get time back and avoid a long drive.
Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.
Travel optionsfrom Brussels to Prague
How to get from Brussels to Prague by train, bus or flight.
Our recommendation
The best way to travel from Brussels to Prague is by taking a train because it’s the best combination of price and speed.
ICE 319 · ICE 1541 · RJX 2518:25 PM13h57Brussels-Midi10:22 AMPrague-Holešovice$601One-way2 transfers
Cheapest
ICE 319 · ICE 1541 · RJX 2518:25 PM13h57Brussels-Midi10:22 AMPrague-Holešovice$601One-way2 transfers
Fastest
FR 6812:35 PM1h30Brussels South Charleroi Airport2:05 PMPrague Vaclav Havel Airport$1651One-way0 transfers
Other options
ICE 319 · EC 459+
243798:25 PM13h00Brussels-Midi9:25 AMPrague hlavní nádraží$691One-way2 transfers
IC 520 · 18981 · 26845 · ICE 8279:56 PM14h25Brussels-Midi12:21 PMPrague hlavní nádraží$901One-way5 transfers
ICE 11 · ICE 529 · 5287 · RJ 5156:23 AM10h58Brussels-Midi5:21 PMPrague hlavní nádraží$1091One-way3 transfers
FlixBus · FlixBus · FlixBus3:40 PM18h30Brussels, Avenue des Magnolias (King Baudouin)10:10 AMPraha, ÚAN Florenc$681One-way2 transfers
FlixBus · FlixBus1:20 AM17h50Brussels, Brussels South (Gare du Midi)7:10 PMPraha, ÚAN Florenc$781One-way1 transfer
FlixBus · FlixBus5:40 PM19h05Brussels, Brussels South (Gare du Midi)12:45 PMPraha, Na Knížecí$781One-way1 transfer
KL1706 · KL13613:10 PM7h25Brussels Airport10:35 PMPrague Vaclav Havel Airport$3271One-way1 transfer
KL1700 · KL13536:20 AM4h10Brussels Airport10:30 AMPrague Vaclav Havel Airport$3281One-way1 transfer
KL1706 · KL13593:10 PM4h40Brussels Airport7:50 PMPrague Vaclav Havel Airport$3281One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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How to Travel from Brussels to Prague?
As you plan your trip Brussels to Prague, you will find that there are three convenient modes of transportation that you may choose from. The three ways to travel to Prague from Brussels are by bus, by train and by plane. There are around 20 buses that depart daily, and take a little over 15 hours on average to arrive at the destination. Three trains serve this route daily, with a journey time of fewer than 10 hours. Lastly, around 25 flights travel from Brussels to Prague each day, with a flight time of 1 hour and 30 minutes.
What is the Cheapest Way To Get from Brussels to Prague?
The cheapest mode of transportation, if booked at least a month or a few weeks in advance, is by taking the plane. Nonetheless, all three methods of transportation can be relatively cheap if booked ahead of the departure date.
What is the Fastest Way to Travel from Brussels to Prague?
The fastest mode of transportation to travel from Brussels to Prague is definitely by plane. By choosing to fly to Prague, you will be able to arrive at your final destination in just one and a half hours. These flights usually depart from either the Brussels Airport (BRU) or the Brussels South Charleroi Airport (CRL) and arrive at the Prague Vaclav Havel Airport (PRG). All of these airports are near the city center.
Find and Book with Omio the Best Tickets from Brussels to Prague
The services provided by the Omio app and website will give you the necessary tools to book any tickets for any mode of transport from Brussels to Prague.
Travel from Brussels to Prague by Bus
Traveling by bus is a great way for you to experience the scenery on the route from Brussels to Prague. You will be able to choose between several departure stations in Brussels, including Brussels South (Gare du Midi), Brussels - Nord and Brussels - Gare du Midi. Travelers will arrive into one of the two main stations in Prague, including Úan Florenc and Hlavní Nádrazí. The average journey takes 15 hours and 27 minutes, with routes either being direct or with up to 4 transfers. The main bus operators for this route are Deutsche Bahn, RegioJet, Eurolines, and FlixBus.
Travel from Brussels to Prague by Train
Another mode of transportation servicing the route from Brussels to Prague is by train. Traveling by train is the second fastest and second most affordable mode of transport. The average journey takes on average 13 hours, and requires between two and four transfers. Only around three trains are scheduled daily and, therefore, it is best to book the tickets ahead of time. The trains usually depart from Brussels-Nord and arrive at Praha Hlavaní Nádrazí station. The train routes are serviced by Deutsche Bahn.
Travel from Brussels to Prague by Plane
The fastest and most affordable mode of transportation to travel from Prague to Amsterdam is by taking the plane. You will find that more than 20 planes depart daily from Brussels Airport (BRU) and Brussels South Charleroi Airport (CRL), and arrive into the Prague Vaclav Havel Airport (PRG). Planes are usually direct on this route and last only an hour and 30 minutes. The flights are operated by RyanAir, Czech Airlines, LOT, KLM, Alitalia, Lufthansa, Austrian Airlines and Air France.
How to get from Brussels to Prague
The Best Way According to our Users
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FAQs: Travel from Brussels to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Brussels to Prague.

This is compared to other travel options from Brussels to Prague:
A bus is $120 (€100) less than a train for this route with tickets for a train from Brussels to Prague costing on average $200 (€167).
A bus is $276 (€231) less than a flight for this route with tickets for a flight from Brussels to Prague costing on average $356 (€298).
Other travel options to Prague take longer:
Train takes on average 11h 15m.
Bus takes on average 16h 18m.
- Around 48 flights per day.
- Around 10 buses per day.
- Around 7 trains per day.
However, we recommend checking specific travel dates for your route between Brussels and Prague as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Brussels Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Brussels-Midi and arrive in Prague hlavní nádraží.
- Buses mostly depart from Brussels, Brussels South (Gare du Midi) and arrive in Praha, ÚAN Florenc.
- Travel with České dráhy, Deutsche Bahn, Alibus, alex-Länderbahn und Vogtlandbahn-GmbH to go to Prague by train.
- Travel with FlixBus, BlaBlaCar Bus to go to Prague by bus.
- Travel with Ryanair, Smartwings, Brussels Airlines, Buzz, KLM, KLM Cityhopper, Lot Polish Airlines, Sas Airways, Air Baltic, Helvetic Airways, Lufthansa, Swiss, Lufthansa Cityline, Cityjet, Qatar Airways, Croatia Airlines, Egypt Air, British Airways, Edelweiss Air, Lufthansa City Airlines, Austrian Airlines, Air Serbia, Turkish Airlines, TAP Portugal to go to Prague by flight.
- 0 direct trains per day with Alibus.
- 2 direct buses per day with FlixBus.
- 4 direct flights per day with Ryanair, Smartwings, Brussels Airlines, Buzz.
Travelling from Brussels to Prague: related information
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