- Must visit
Charleston Museum
Often called America’s first museum, with collections on Lowcountry history, natural history, decorative arts, and city development.
Cheapest price
$111
Average price
$127
Fastest journey
18 h 45 m
Average duration
18 h 55 m
Buses per day
2
Distance
783 km
The best way to find a cheap bus ticket from Baltimore, MD to Charleston, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Baltimore, MD to Charleston, SC will cost around $127 if you buy it on the day, but the cheapest tickets can be found for only $111.
Of the 2 buses that leave Baltimore, MD for Charleston, SC on Thu, May 28, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, May 28 the direct buses cover the 783 km distance in an average of 18 h 55 m but if you time it right, some buses will get you there in just 18 h 45 m .
On Thu, May 28 the slowest buses will take 19 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the train as it is the most popular option from Baltimore, MD to Charleston, SC among Omio's users. If you are prioritising price take the bus with prices starting from $83. For those with little time consider booking a flight which can get you there in 6h 55m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.7kg. The ticket price range depends on the travel mode: a bus costs an average of $83, and a flight costs an average of $89.
Distance: 486 miles (783 km)
| Bus | Most popular Train | Flight | Driving |
|---|---|---|---|
$153 Average price Cheapest | $183 Average price | $306 Average price | $111 Average price (fuel + tolls) |
19h 31m Average total duration 19h 1m Onboard + 30m Additional time* | 11h 12m Average total duration 10h 42m Onboard + 30m Additional time* | 9h 55m Average total duration Fastest 6h 55m Onboard + 3h 0m Additional time* | 9h 59m Average total duration (door-to-door) |
0.8 - 2.0kg CO2 emissions | 0.2 - 0.7kg CO2 emissions Lowest | 2.3 - 4.7kg CO2 emissions | - CO2 emissions |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Baltimore, MD to Charleston, SC:
A bus is $30 (€24) less than a train for this route with tickets for a train from Baltimore, MD to Charleston, SC costing on average $183 (€147).
A bus is $153 (€124) less than a flight for this route with tickets for a flight from Baltimore, MD to Charleston, SC costing on average $306 (€247).
Other travel options to Charleston, SC take longer:
Train takes on average 10h 42m.
Bus takes on average 19h 1m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:25AM | Arrival Time 10:30PM | Duration 19h05 | Departure days Everyday | Cheapest price $83 |
Operator Greyhound | Departure Time 03:45AM | Arrival Time 10:30PM | Duration 18h45 | Departure days Sun | Cheapest price $83 |
Operator FlixBus | Departure Time 04:25AM | Arrival Time 11:30PM | Duration 19h05 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $109 |
Operator Greyhound | Departure Time 04:45AM | Arrival Time 11:30PM | Duration 18h45 | Departure days Thu | Cheapest price $111 |
Operator Greyhound | Departure Time 05:35AM | Arrival Time 10:30PM | Duration 16h55 | Departure days Fri | Cheapest price $116 |
The table below shows live departures for Baltimore, MD to Charleston, SC buses for tomorrow, Wednesday, May 27. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:25 AM Baltimore, MD | 19h05 | 10:30 PM Charleston, SC | 0 transfersDirect | |
![]() | 4:45 AM Baltimore, MD | 18h45 | 11:30 PM Charleston, SC | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Baltimore, MD to Charleston, SC run on average 2 times per day, taking around 19h 1m. Cheap bus tickets for this journey start at $83 (€67) if you book in advance.
The earliest bus runs at 00:25, the last at 23:45. The fastest bus covers the 486 miles (783 km) distance in 16h 55m.
Distance 486 miles (783 km) |
Average bus duration 19h 1m |
Cheapest ticket price $83 (€67) |
Buses per day 2 |
Fastest bus 16h 55m |
First bus 12:25 AM |
Last bus 11:45 PM |
Cheapest Month Oct |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jul - Sep |
Busiest Day Fri |
Least Busy Day Fri |
Best time to book 4 days |
Discover the best of Charleston — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Charleston trip today.
Often called America’s first museum, with collections on Lowcountry history, natural history, decorative arts, and city development.
Charleston’s leading art museum, known for American art with strong connections to the South and rotating exhibitions.
A major modern museum exploring African American history and culture, located at a nationally significant waterfront site.
Charleston’s best-known shopping and strolling street, mixing historic architecture, boutiques, and lively city atmosphere.
A compact historic district with galleries, churches, courtyards, and some of the city’s most atmospheric old streets.
A popular harborfront park known for relaxing walks, pier views, and the famous Pineapple Fountain.
A Lowcountry staple of sautéed shrimp served over creamy grits, often with bacon or gravy. It is one of Charleston’s most iconic dishes.
A rich, creamy crab soup finished with crab roe and a splash of sherry. It is a classic Charleston specialty with deep local roots.
Also called Lowcountry boil, this one-pot dish combines shrimp, sausage, corn, and potatoes. It is a beloved coastal gathering food.
One of Charleston’s best-known fine dining restaurants, praised for seasonal Southern cuisine and polished service.
A celebrated restaurant focused on Southern ingredients and refined Lowcountry cooking in a historic setting.
A popular waterfront spot known for seafood, shrimp and grits, and relaxed harbor views.
Moderate by U.S. standards. Hotels can be pricey in peak season, but casual dining and coffee are fairly typical for a mid-size tourist city.
Tip 18-20% in restaurants; 20%+ for excellent service. Bartenders: USD 1-2 per drink. Taxis/rideshares: 10-15%. Hotel staff: USD 2-5. Not expected for counter service, but appreciated.
Find answers to the most common questions about traveling from Baltimore, MD to Charleston, SC by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Charleston, SC, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need