- Must visit
Vatican Museums
World-famous museum complex with the Sistine Chapel, Raphael Rooms, and major classical and Renaissance collections. Timed entry is strongly recommended due to very high demand.
Cheapest price
$73
Average price
$97
Fastest journey
13 h 50 m
Average duration
15 h 54 m
Buses per day
4
Distance
517 km
The best way to find a cheap bus ticket from Agrigento to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Agrigento to Rome will cost around $97 if you buy it on the day, but the cheapest tickets can be found for only $73.
Of the 4 buses that leave Agrigento for Rome on Sat, Jun 20, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 20 the direct buses cover the 517 km distance in an average of 15 h 54 m but if you time it right, some buses will get you there in just 13 h 50 m .
On Sat, Jun 20 the slowest buses will take 19 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
S122
FlixBus · FlixBus
FlixBus
FlixBus
S122
FlixBus
FlixBus
FlixBus · FlixBusOmio recommends booking the bus as it is the most popular option from Agrigento to Rome among Omio's users. If you are prioritising price take the ferry with prices starting from $62. For those with little time consider booking a train which can get you there in 11h 4m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a ferry costs an average of $62, and a train costs an average of $45.
Distance: 321 miles (517 km)
Most popular Bus | Train | Ferry | Driving |
|---|---|---|---|
$81 Average price | $103 Average price | $67 Average price Cheapest | $80 Average price (fuel + tolls) |
14h 6m Average total duration 13h 36m Onboard + 30m Additional time* | 11h 34m Average total duration Fastest 11h 4m Onboard + 30m Additional time* | 15h 0m Average total duration 14h 0m Onboard + 1h 0m Additional time* | 10h 24m Average total duration (door-to-door) |
0.5 - 1.3kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | - CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular ferry company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Agrigento to Rome:
A ferry is $14 (€12) less than a bus for this route with tickets for a bus from Agrigento to Rome costing on average $81 (€66).
A ferry is $37 (€30) less than a train for this route with tickets for a train from Agrigento to Rome costing on average $103 (€85).
Other travel options to Rome take longer:
Train takes on average 11h 4m.
Bus takes on average 13h 36m.
Ferry takes on average 14h 0m.
You'll arrive about -4h -12m sooner (13h 36m by bus vs 10h 24m by car) and save roughly $-0.60 (€-0.49) compared to fuel and tolls ($81 (€66) vs $80 (€66)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by Autoservizi Salemi, FlixBus, Salemi, BlaBlaCar.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 04:55AM | Arrival Time 08:30PM | Duration 15h35 | Departure days Thu | Cheapest price $112 |
Operator FlixBus | Departure Time 05:55AM | Arrival Time 09:30PM | Duration 15h35 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $85 |
Operator BlaBlaCar | Departure Time 11:30AM | Arrival Time 10:30PM | Duration 11h00 | Departure days Mon | Cheapest price $63 |
Operator Salemi | Departure Time 02:25PM | Arrival Time 04:15AM | Duration 13h50 | Departure days Thu | Cheapest price $74 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 11:50AM | Duration 19h35 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $67 |
Operator Salemi | Departure Time 04:25PM | Arrival Time 06:15AM | Duration 13h50 | Departure days Mon, Tue, Wed, Fri, Sat, Sun | Cheapest price $37 |
Operator FlixBus | Departure Time 04:30PM | Arrival Time 10:40AM | Duration 18h10 | Departure days Thu | Cheapest price $134 |
The table below shows live departures for Agrigento to Rome buses for today, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 5:55 AM Agrigento, Piazzale Rosselli | 15h35 | 9:30 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 4:15 PM Agrigento, Piazzale Rosselli | 14h35 | 6:50 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 4:15 PM Agrigento, Piazzale Rosselli | 19h35 | 11:50 AM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
S122 | 4:25 PM Agrigento, Piazzale V. Emanuele (Cinema Astor) | 13h50 | 6:15 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Agrigento to Rome run on average 3 times per day, taking around 13h 36m. Cheap bus tickets for this journey start at $48 (€39) but you can travel from only $45 (€37) by train.
There are 2 buses per day. The earliest bus runs at 01:15, the last at 23:55. The fastest bus covers the 321 miles (517 km) distance in 13h 50m.
Distance 321 miles (517 km) |
Average bus duration 13h 36m |
Cheapest ticket price $48 (€39) |
Buses per day 3 |
Direct buses 2 |
Fastest bus 13h 50m |
First bus 1:15 AM |
Last bus 11:55 PM |
Cheapest Month Aug |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Thu |
Best time to book 21 days |
Discover the best of Rome — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Rome trip today.
World-famous museum complex with the Sistine Chapel, Raphael Rooms, and major classical and Renaissance collections. Timed entry is strongly recommended due to very high demand.
One of Rome’s finest art museums, known for Bernini sculptures and paintings by Caravaggio and Raphael. Advance reservation is typically required because entry is strictly timed.
The city’s historic civic museums on Capitoline Hill, featuring Roman bronzes, imperial sculpture, and art with views over the Forum.
Elegant Baroque square built on an ancient stadium, lined with fountains, palaces, and lively street life. A classic area for strolling and people-watching.
Atmospheric neighborhood of narrow lanes, ivy-covered buildings, and busy evening streets. Popular with visitors but still one of Rome’s most characteristic areas.
Famous monumental staircase linking Piazza di Spagna and Trinità dei Monti. A highly photographed landmark and social-media favorite.
A classic Roman pasta with pecorino Romano and black pepper. It is one of the city’s most iconic dishes and a benchmark of Roman cooking.
Traditional Roman pasta made with guanciale, egg yolk, pecorino Romano, and black pepper. It is famous for its rich sauce without cream.
A beloved pasta sauce of tomato, guanciale, and pecorino Romano, closely tied to Rome’s culinary identity and served with bucatini or rigatoni.
Rome’s most famous fine-dining restaurant, offering elegant tasting menus, panoramic views, and one of the city’s most prestigious dining experiences.
A historic trattoria near the Pantheon, famous for traditional Roman dishes such as gricia, amatriciana, and seasonal specialties.
A celebrated central Rome venue known for classic Roman pasta, exceptional cured meats, and a refined but lively atmosphere.
Rome is moderate by Western Europe standards: sights are affordable, but central hotels and tourist-area dining cost more.
Service is usually included or modest. Tipping is not required, but rounding up or leaving EUR 1-2 at cafes and 5-10% at restaurants for good service is appreciated.
Official public transport app
Rome, Via Marsala / Viale Enrico De Nicola -> Roma Termini
Find answers to the most common questions about traveling from Agrigento to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

Most Agrigento to Rome buses use the Agrigento, Piazzale Rosselli to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Agrigento and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need