- Must visit
Santa Maria della Scala
A vast former hospital complex opposite the cathedral, now a museum center with archaeological finds, frescoed halls, and temporary exhibitions. One of Siena’s richest cultural sites.
Cheapest price
$72
Average price
$117
Fastest journey
18 h 50 m
Average duration
21 h 40 m
Buses per day
3
Distance
694 km
The best way to find a cheap bus ticket from Agrigento to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Agrigento to Siena will cost around $117 if you buy it on the day, but the cheapest tickets can be found for only $72.
Of the 3 buses that leave Agrigento for Siena on Sat, Jun 06, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Jun 06 the direct buses cover the 694 km distance in an average of 21 h 40 m but if you time it right, some buses will get you there in just 18 h 50 m .
On Sat, Jun 06 the slowest buses will take 23 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Omio recommends booking the bus as it is the most popular option from Agrigento to Siena among Omio's users. If you are prioritising price take the ferry with prices starting from $46. For those with little time consider booking a train which can get you there in 18h 15m. The ticket price range depends on the travel mode: a ferry costs an average of $46, and a train costs an average of $205.
Distance: 431 miles (694 km)
Most popular Bus | Ferry | Train | Driving |
|---|---|---|---|
$121 Average price | $53 Average price Cheapest | $221 Average price | $26 Average price (fuel + tolls) |
18h 56m Average total duration 18h 26m Onboard + 30m Additional time* | 20h 50m Average total duration 19h 50m Onboard + 1h 0m Additional time* | 18h 45m Average total duration Fastest 18h 15m Onboard + 30m Additional time* | 12h 15m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Agrigento to Siena:
A ferry is $68 (€55) less than a bus for this route with tickets for a bus from Agrigento to Siena costing on average $121 (€99).
A ferry is $167 (€136) less than a train for this route with tickets for a train from Agrigento to Siena costing on average $221 (€179).
Other travel options to Siena take longer:
Bus takes on average 18h 26m.
Ferry takes on average 19h 50m.
You'll arrive about -7h -11m sooner (18h 26m by bus vs 12h 15m by car) and save roughly $-95.77 (€-77.71) compared to fuel and tolls ($121 (€99) vs $26 (€21)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by FlixBus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:55AM | Arrival Time 10:40PM | Duration 18h45 | Departure days Mon, Wed, Thu, Fri, Sat | Cheapest price $115 |
Operator FlixBus | Departure Time 04:55AM | Arrival Time 11:40PM | Duration 18h45 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $89 |
Operator FlixBus | Departure Time 02:15PM | Arrival Time 03:10PM | Duration 24h55 | Departure days Mon, Thu, Fri, Sat, Sun | Cheapest price $123 |
Operator FlixBus | Departure Time 04:30PM | Arrival Time 11:20AM | Duration 18h50 | Departure days Wed, Thu, Fri, Sat, Sun | Cheapest price $72 |
The table below shows live departures for Agrigento to Siena buses for tomorrow, Saturday, June 6. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:55 AM Agrigento | 23h35 | 3:30 AM Siena | 0 transfersDirect | |
![]() | 2:15 PM Agrigento | 22h35 | 12:50 PM Siena | 0 transfersDirect | |
![]() | 4:30 PM Agrigento | 18h50 | 11:20 AM Siena | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Agrigento to Siena run on average 5 times per day, taking around 18h 26m. Cheap bus tickets for this journey start at $56 (€46) but you can travel from only $46 (€37) by ferry.
There are 1 buses per day. The earliest bus runs at 00:45, the last at 23:39. The fastest bus covers the 431 miles (694 km) distance in 18h 40m.
Distance 431 miles (694 km) |
Average bus duration 18h 26m |
Cheapest ticket price $56 (€46) |
Buses per day 5 |
Direct buses 1 |
Fastest bus 18h 40m |
First bus 12:45 AM |
Last bus 11:39 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jul - Sep |
Discover the best of Siena — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Siena trip today.
A vast former hospital complex opposite the cathedral, now a museum center with archaeological finds, frescoed halls, and temporary exhibitions. One of Siena’s richest cultural sites.
Siena’s civic museum inside Palazzo Pubblico, famous for Ambrogio Lorenzetti’s fresco cycle Allegory of Good and Bad Government and rooms tied to the city’s republican history.
The cathedral museum complex includes works linked to the Duomo, including sculpture, stained glass, and access to important cathedral-related spaces.
Siena’s shell-shaped central square is one of Italy’s most famous urban spaces, home to the Palio and essential for understanding the city’s civic identity.
A famous panoramic terrace in the unfinished cathedral extension, popular for skyline photos and increasingly prominent on social media.
This elevated panorama over Siena’s rooftops and countryside is especially sought out for sunset photos and dramatic views over the cathedral area.
Thick hand-rolled pasta from southern Tuscany, usually served with a garlicky tomato sauce made with aglione, a local mild garlic. It is one of the most emblematic pasta dishes around Siena.
A traditional Tuscan bread and vegetable soup, typically made with beans, cavolo nero, and stale bread, then reheated to deepen the flavor. It is a classic rustic dish eaten across Siena.
A thick tomato and bread soup with olive oil, garlic, and basil. It is a simple but beloved Tuscan staple that showcases the region's bread-based cucina povera tradition.
Well-known traditional restaurant in a historic setting, celebrated for Tuscan classics, pasta, and meat dishes, with a warm and refined atmosphere.
Established upscale dining room near the center, known for elegant Tuscan cuisine, seasonal ingredients, and polished service in a classic Sienese setting.
Long-running central restaurant appreciated for honest Tuscan cooking, generous portions, and a simple local feel. A solid choice for classic Sienese fare.
Moderate by Italian standards. Historic-center dining costs more, but cafes, bakeries, and simple trattorias can be good value.
Service is often included or covered by coperto. Tipping is not required, but rounding up or leaving 5-10% for very good restaurant service is appreciated. Small change for taxis is enough.
Official public transport app
Siena, Stazione FS (Piazzale Carlo Rosselli) -> Piazza del Campo, Siena
Find answers to the most common questions about traveling from Agrigento to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

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