- Must visit
Museo Civico
Siena’s main civic museum displays Lorenzetti’s frescoes and superb medieval art inside the historic town hall. It is essential for understanding the city.
Cheapest price
$88
Average price
$114
Fastest journey
18 h 45 m
Average duration
18 h 47 m
Buses per day
3
Distance
694 km
The best way to find a cheap bus ticket from Agrigento to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Agrigento to Siena will cost around $114 if you buy it on the day, but the cheapest tickets can be found for only $88.
Of the 3 buses that leave Agrigento for Siena on Wed, Jul 22, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jul 22 the direct buses cover the 694 km distance in an average of 18 h 47 m but if you time it right, some buses will get you there in just 18 h 45 m .
On Wed, Jul 22 the slowest buses will take 18 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






Omio recommends booking the bus as it is the most popular option from Agrigento to Siena among Omio's users. If you are prioritising price take the ferry with prices starting from $45. For those with little time consider booking a train which can get you there in 18h 15m. The ticket price range depends on the travel mode: a ferry costs an average of $45, and a train costs an average of $202.
Distance: 431 miles (694 km)
Most popular Bus | Ferry | Train | Driving |
|---|---|---|---|
$120 Average price | $53 Average price Cheapest | $218 Average price | $25 Average price (fuel + tolls) |
18h 56m Average total duration 18h 26m Onboard + 30m Additional time* | 20h 50m Average total duration 19h 50m Onboard + 1h 0m Additional time* | 18h 45m Average total duration Fastest 18h 15m Onboard + 30m Additional time* | 12h 15m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Agrigento to Siena:
A ferry is $67 (€55) less than a bus for this route with tickets for a bus from Agrigento to Siena costing on average $120 (€99).
A ferry is $165 (€136) less than a train for this route with tickets for a train from Agrigento to Siena costing on average $218 (€179).
Other travel options to Siena take longer:
Bus takes on average 18h 26m.
Ferry takes on average 19h 50m.
You'll arrive about -7h -11m sooner (18h 26m by bus vs 12h 15m by car) and save roughly $-94.53 (€-77.71) compared to fuel and tolls ($120 (€99) vs $25 (€21)). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by FlixBus.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 03:55AM | Arrival Time 03:30AM | Duration 23h35 | Departure days Mon, Wed, Thu, Fri, Sat | Cheapest price $113 |
Operator FlixBus | Departure Time 04:55AM | Arrival Time 11:40PM | Duration 18h45 | Departure days Mon, Tue, Wed, Thu, Fri | Cheapest price $88 |
Operator FlixBus | Departure Time 05:55AM | Arrival Time 12:40AM | Duration 18h45 | Departure days Sun | Cheapest price $153 |
Operator FlixBus | Departure Time 02:15PM | Arrival Time 12:50PM | Duration 22h35 | Departure days Mon, Thu, Fri, Sat | Cheapest price $122 |
Operator FlixBus | Departure Time 04:15PM | Arrival Time 11:25AM | Duration 19h10 | Departure days Sun | Cheapest price $109 |
Operator FlixBus | Departure Time 04:30PM | Arrival Time 11:20AM | Duration 18h50 | Departure days Wed, Thu, Fri, Sat | Cheapest price $71 |
The table below shows live departures for Agrigento to Siena buses for tomorrow, Wednesday, July 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 3:55 AM Agrigento | 18h45 | 10:40 PM Siena | 0 transfersDirect | |
![]() | 4:55 AM Agrigento | 18h45 | 11:40 PM Siena | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare train, bus, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Agrigento to Siena run on average 5 times per day, taking around 18h 26m. Cheap bus tickets for this journey start at $56 (€46) but you can travel from only $45 (€37) by ferry.
There are 1 buses per day. The earliest bus runs at 00:45, the last at 23:39. The fastest bus covers the 431 miles (694 km) distance in 18h 40m.
Distance 431 miles (694 km) |
Average bus duration 18h 26m |
Cheapest ticket price $56 (€46) |
Buses per day 5 |
Direct buses 1 |
Fastest bus 18h 40m |
First bus 12:45 AM |
Last bus 11:39 PM |
Cheapest Month Feb |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jul - Sep |
Discover the best of Siena — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Siena trip today.
Siena’s main civic museum displays Lorenzetti’s frescoes and superb medieval art inside the historic town hall. It is essential for understanding the city.
This major museum complex occupies a former hospital and combines archaeology, frescoes, chapels, and underground spaces in a memorable setting.
The cathedral museum preserves sculptures, stained glass, and treasures from the Duomo complex, including close views of masterpieces and architecture.
Siena’s iconic shell-shaped square is the social and visual heart of the city, perfect for architecture, people-watching, and understanding the Palio.
This broad square in front of the cathedral frames some of Siena’s finest Gothic monuments and is a natural stop on any walking route.
The city’s main pedestrian street links major sights with shops and noble facades. It is ideal for a first walk through Siena’s historic core.
Thick rustic soup of bread, beans, cavolo nero and vegetables. A Tuscan staple in Siena, prized for peasant roots and deep, comforting flavor.
Dense vegetable and bread soup made with beans, tomato, onion, celery and stale bread. Traditional cucina povera, often linked to Sienese home cooking.
Hand-rolled thick spaghetti, usually served with rich garlic-forward tomato sauce or duck ragù. A classic Tuscan pasta common in Siena trattorie.
Popular central trattoria focused on pici, ribollita and other regional staples, offering a casual atmosphere near major sights.
Well-known osteria for classic Tuscan and Sienese dishes, with a cozy brick interior and strong local wine selection.
Elegant Michelin-starred restaurant near Piazza del Campo, known for refined Tuscan tasting menus and polished historic atmosphere.
Moderate for Italy: lodging and dining cost more than small towns, but transit is limited and many sights are walkable.
Service is often included or covered by coperto. Round up or leave 5-10% for great restaurant service; taxis are usually rounded up; cafés need no tip.
Official public transport app
Siena, Stazione FS (Piazzale Carlo Rosselli) -> Piazza del Campo, Siena
Find answers to the most common questions about traveling from Agrigento to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

Most Agrigento to Siena buses use the Agrigento, Piazzale Rosselli to Siena, Stazione FS (Piazzale Carlo Rosselli) station pair, with some services arriving at Siena, Siena/Viale Pietro Toselli. Use this guide to compare Agrigento and Siena bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Here are some other resources that might have the information you need