Travel Information
Compare train and bus for Milan to Karlsruhe
Omio recommends booking the train as it is the most popular option from Milan to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from €26. For those with little time consider booking a train which can get you there in 6h 8m. The ticket price range depends on the travel mode: a bus costs an average of €26, and a train costs an average of €56.
Distance: 247 miles (398 km)
Compare train with
Most popular Train | Bus |
|---|---|
€109 Average price | €39 Average price Cheapest |
6h 38m Average total duration Fastest 6h 8m Onboard + 30m Additional time* | 10h 41m Average total duration 10h 11m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Travel optionsfrom Milan to Karlsruhe
How to get from Milan to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Milan to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
FlixBusCheapest
FlixBusFastest
DE4354+
ICE 915 · ICE 71Other options
FlixBus
FlixBus
4743 · 30492
DE4358+
ICE 109
DE4358+
ICE 203
U21969+
ICE 205Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Milan to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Milan to Karlsruhe.

This is compared to other travel options from Milan to Karlsruhe:
A bus is $37 (€30) less than a train for this route with tickets for a train from Milan to Karlsruhe costing on average $70 (€56).
Other travel options to Karlsruhe take longer:
Bus takes on average 7h 20m.
- Around 9 buses per day.
- Around 1 flights per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Milan and Karlsruhe as scheduled services by train and bus can vary by season or day of the week.
- Flights mostly depart from Milan Bergamo Orio al Serio Airport and arrive in Karlsruhe/Baden-Baden Airport.
- Trains mostly depart from Milan Centrale and arrive in Karlsruhe Hbf.
- Buses mostly depart from Milano, Autostazione Lampugnano and arrive in Karlsruhe Hbf.
- Travel with FlixBus, BlaBlaCar Bus, Marino Autolinee to go to Karlsruhe by bus.
- Travel with Ryanair, KM Malta Airlines, Eurowings to go to Karlsruhe by flight.
- Travel with Deutsche Bahn, Trenitalia, Trenitalia EuroCity to go to Karlsruhe by train.
- 6 direct buses per day with FlixBus, BlaBlaCar Bus, Marino Autolinee.
- 1 direct flights per day with KM Malta Airlines.
- 0 direct trains per day with Trenitalia EuroCity.
Travelling from Milan to Karlsruhe: related information
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