Travel Information
Compare train, bus, and flight for Milan to Karlsruhe
Omio recommends booking the train as it is the most popular option from Milan to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from €24. For those with little time consider booking a flight which can get you there in 1h 7m. The ticket price range depends on the travel mode: a bus costs an average of €24, and a train costs an average of €80.
Distance: 247 miles (398 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€119 Average price | €42 Average price Cheapest | €71 Average price |
6h 38m Average total duration 6h 8m Onboard + 30m Additional time* | 10h 55m Average total duration 10h 25m Onboard + 30m Additional time* | 4h 7m Average total duration Fastest 1h 7m Onboard + 3h 0m Additional time* |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Travel optionsfrom Milan to Karlsruhe
How to get from Milan to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Milan to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
FlixBusCheapest
4743 · 30492Fastest
DE4356+
ICE 915 · ICE 71Other options
EC 150
FlixBus
FlixBus
FlixBus
U21969+
ICE 203
U21967+
ICE 103
U21969+
ICE 205Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Milan to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Milan to Karlsruhe.

There are 2 options to travel from Milan to Karlsruhe including taking a train or bus.
The cheapest way to go to Karlsruhe from Milan is by taking a bus, which costs on average $26 (€23).
This is compared to other ways of getting from Milan to Karlsruhe:
A bus is () less than a flight with an average ticket price of () from Milan to Karlsruhe.
Taking a bus costs $29 (€26) less than taking a train, which average ticket prices of $55 (€50).
The quickest way to travel from Milan to Karlsruhe is by train, which takes on average 6 h 19 min compared to other travel options that take longer:
Getting to Karlsruhe by bus takes 8 h 10 min on average.
The distance is approximately 247 miles (398 km) from Milan to Karlsruhe.
The average frequency per day from Milan to Karlsruhe is:
- Around 4 buses per day.
- Around 1 train per day.
However, we recommend checking specific travel dates for your route from Milan to Karlsruhe as scheduled services by train or bus can vary by season or day of the week.
These are the most popular departure and arrival points from Milan to Karlsruhe:
- Buses most often depart from Milan at Milano, Autostazione Lampugnano and arrive in Karlsruhe at Karlsruhe Hbf.
- Flights most often depart from Milan at Milan Bergamo Orio al Serio Airport and arrive in Karlsruhe at Karlsruhe/Baden-Baden Airport.
- Trains from Milan to Karlsruhe most often leave from Milan Centrale and arrive in Karlsruhe Hbf.
The following travel companies offer services from Milan to Karlsruhe:
- FlixBus, BlaBlaCar Bus or Marino Autolinee can get you to Karlsruhe by bus. You can find a good deal for bus tickets with FlixBus from Milan to Karlsruhe for $26 (€23) on Omio.
- Travel with Ryanair or Eurowings for flights to Karlsruhe. If you’re looking for a good deal on tickets, check for Ryanair Milan to Karlsruhe tickets on Omio for $19 (€17).
- Deutsche Bahn or Trenitalia EuroCity can get you to Karlsruhe by train. You can find a good deal for train tickets with Deutsche Bahn from Milan to Karlsruhe for $55 (€50) on Omio.
Yes, there are direct routes from Milan to Karlsruhe with the following travel companies:
- You can find 3 direct buses per day to take to Karlsruhe with FlixBus, BlaBlaCar Bus or Marino Autolinee.
- You can find 1 direct train per day to take to Karlsruhe with Trenitalia EuroCity.
Direct services to Karlsruhe tend to save you time and add more convenience as you won't need to transfer at another stop in between, so it's worth paying attention to before booking tickets for your trip.
Travelling from Milan to Karlsruhe: related information
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