Travel Information
Compare train and bus for Milan to Karlsruhe
Omio recommends booking the bus as it is the most popular option from Milan to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from $35. For those with little time consider booking a train which can get you there in 6h 8m. The ticket price range depends on the travel mode: a bus costs an average of $35, and a train costs an average of $78.
Distance: 247 miles (398 km)
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
$50 Average price Cheapest | $162 Average price | $176 Average price (fuel + tolls) |
10h 32m Average total duration 10h 2m Onboard + 30m Additional time* | 6h 38m Average total duration Fastest 6h 8m Onboard + 30m Additional time* | 6h 18m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Milan to Karlsruhe:
A bus is $113 (€91) less than a train for this route with tickets for a train from Milan to Karlsruhe costing on average $162 (€131).
Other travel options to Karlsruhe take longer:
Train takes on average 6h 8m.
Bus takes on average 10h 2m.
Travel optionsfrom Milan to Karlsruhe
How to get from Milan to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Milan to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
FlixBus8:25 PM7h20Milano, Autostazione Lampugnano3:45 AMKarlsruhe Hbf$671One-way0 transfers
Cheapest
FlixBus8:25 PM7h20Milano, Autostazione Lampugnano3:45 AMKarlsruhe Hbf$671One-way0 transfers
Fastest
DE4358+
ICE 919 · ICE 7312:00 PM3h23Milan Malpensa Airport3:23 PMKarlsruhe Hbf$2431One-way2 transfers
Other options
EC 15011:10 AM6h19Milan Centrale5:29 PMKarlsruhe Hbf$2751One-way0 transfers
FlixBus7:15 AM8h20Milano, Autostazione Lampugnano3:35 PMKarlsruhe Hbf$731One-way0 transfers
FlixBus1:15 AM9h55Milano, Autostazione Lampugnano11:10 AMKarlsruhe Hbf$741One-way0 transfers
4743 · 304923:20 PM11h45Milano, Autostazione Lampugnano3:05 AMKarlsruhe, Hinterm Hauptbahnhof (Südeingang)$771One-way1 transfer
EC5403+
ICE 1037:00 AM3h59Milan Linate Airport10:59 AMKarlsruhe Hbf$2201One-way1 transfer
EC5403+
ICE 915 · ICE 717:00 AM4h23Milan Linate Airport11:23 AMKarlsruhe Hbf$2201One-way2 transfers
DE4358+
ICE 20312:00 PM8h59Milan Malpensa Airport8:59 PMKarlsruhe Hbf$2251One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Milan to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Milan to Karlsruhe.

This is compared to other travel options from Milan to Karlsruhe:
A bus is $113 (€91) less than a train for this route with tickets for a train from Milan to Karlsruhe costing on average $162 (€131).
Other travel options to Karlsruhe take longer:
Train takes on average 6h 8m.
Bus takes on average 10h 2m.
- Around 9 buses per day.
- Around 1 flights per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Milan and Karlsruhe as scheduled services by train and bus can vary by season or day of the week.
- Flights mostly depart from Milan Bergamo Orio al Serio Airport and arrive in Karlsruhe/Baden-Baden Airport.
- Trains mostly depart from Milan Centrale and arrive in Karlsruhe Hbf.
- Buses mostly depart from Milano, Autostazione Lampugnano and arrive in Karlsruhe Hbf.
- Travel with FlixBus, BlaBlaCar Bus, Marino Autolinee to go to Karlsruhe by bus.
- Travel with Ryanair, Malta Air, Eurowings to go to Karlsruhe by flight.
- Travel with Deutsche Bahn, Trenitalia, Trenitalia EuroCity to go to Karlsruhe by train.
- 6 direct buses per day with FlixBus, BlaBlaCar Bus, Marino Autolinee.
- 1 direct flights per day with Malta Air.
- 0 direct trains per day with Deutsche Bahn, Trenitalia EuroCity.
Travelling from Milan to Karlsruhe: related information
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