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Compare train, bus, and flight for Prague to Frankfurt am Main
Omio recommends booking the train as it is the most popular option from Prague to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from €25. For those with little time consider booking a flight which can get you there in 1h 59m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €25, and a flight costs an average of €109.
Distance: 254 miles (409 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€69 Average price | €39 Average price Cheapest | €191 Average price |
7h 15m Average total duration 6h 45m Onboard + 30m Additional time* | 12h 1m Average total duration 11h 31m Onboard + 30m Additional time* | 4h 59m Average total duration Fastest 1h 59m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.0kg CO2 emissions | 1.2 - 2.5kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Prague to Frankfurt am Main
How to get from Prague to Frankfurt am Main by train, bus or flight.
Our recommendation
The best way to travel from Prague to Frankfurt am Main is by taking a bus because it’s the best combination of price and speed.
FlixBusCheapest
(Prague -> Amsterdam)Fastest
DE4406Other options
rj 178 · ICE 1558
rj 382 · IC 2442 · ICE 691
rj 178 · IC 2440 · ICE 599
FlixBus
FlixBus
FlixBus
LO528 · LO379
LO524 · LO379
LO530 · LO379Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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How to get from Prague to Frankfurt am Main
The Best Way According to our Users
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FAQs: Travel from Prague to Frankfurt am Main
Travel to Frankfurt am Main easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Frankfurt am Main.

There are 3 travel options from Prague to Frankfurt am Main: bus, train or flight.
The cheapest way to go to Frankfurt am Main from Prague is by taking a train, which costs on average $23 (€21).
This is compared to other ways of getting from Prague to Frankfurt am Main:
A train is $5 (€5) less than a bus for this route with tickets for a bus from Prague to Frankfurt am Main costing on average $29 (€26).
A train is $89 (€80) less than a flight with an average ticket price of $112 (€101) from Prague to Frankfurt am Main.
The fastest way from Prague to Frankfurt am Main is by flight with an average journey time of 1 h 10 min.
There are alternative travel options to Frankfurt am Main that take longer:
Bus takes on average 6 h 25 min.
Train takes on average 7 h 2 min.
The distance from Prague to Frankfurt am Main is approximately 254 miles (409 km).
The average frequency per day from Prague to Frankfurt am Main is:
- 35 buses a day.
- 37 flights a day.
- 12 trains a day.
However, we recommend checking specific travel dates for your route to Frankfurt am Main from Prague as scheduled services by bus, train or flight can vary by season or day of the week.
These are the most popular departure and arrival points when traveling from Prague to Frankfurt am Main:
- Most travelers take a bus from Prague, Central Train Station to Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36).
- Most travelers who purchase a plane ticket from Prague to Frankfurt am Main depart from Prague Vaclav Havel Airport to Frankfurt am Main Airport.
The following travel companies offer services from Prague to Frankfurt am Main:
- FlixBus can take you to Frankfurt am Main by bus. If searching for a good deal on buses, you can find tickets for FlixBus from Prague to Frankfurt am Main for $35 (€32).
- Lufthansa, LOT Polish Airlines, KLM, Eurowings, Lufthansa Cityline (2), Austrian Airlines, KLM Cityhopper, Brussels Airlines or LAER can get you to Frankfurt am Main by plane. You can find a good deal for plane tickets with LOT Polish Airlines from Prague to Frankfurt am Main for $112 (€101) on Omio.
- Deutsche Bahn or ÖBB | Euro City (EC) can take you to Frankfurt am Main by train. If searching for a good deal on trains, you can find tickets for Deutsche Bahn from Prague to Frankfurt am Main for $23 (€21).
Yes, there are direct services available from Prague to Frankfurt am Main with the following travel companies:
- Direct bus available with FlixBus 13 direct buses per day.
- 4 direct flights per day with Lufthansa.
Direct services tend to save you time and add more convenience in getting you to Frankfurt am Main as you won't need to transfer at another stop in between, so it's worth paying attention to before booking your tickets between Prague and Frankfurt am Main.
Travelling from Prague to Frankfurt am Main: related information
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