How to travel from Prague to Frankfurt am Main

Sat, Oct 10
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Deutsche Bahn
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České dráhy
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Deutsche Bahn
Lufthansa
České dráhy
Leo Express
1,000+ more
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Travel Information

Compare train, bus, and flight for Prague to Frankfurt am Main

Omio recommends booking the train as it is the most popular option from Prague to Frankfurt am Main among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $45 For those with little time, consider booking a flight, which has an average total journey time of 4h 53m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $45, while a flight costs an average of $339.

Distance: 254 miles (409 km)

Compare train with

Most popular
Train
Bus
Flight
Driving

$110

Average price

$45

Average price

Cheapest

$339

Average price

$110

Average price

(fuel + tolls)

7h 43m

Average total duration

7h 13m

Onboard

+

30m

Additional time*

8h 11m

Average total duration

7h 41m

Onboard

+

30m

Additional time*

4h 53m

Average total duration

Fastest

2h 53m

Onboard

+

2h 0m

Additional time*

5h 1m

Average total duration

(door-to-door)

0.1 - 0.4kg

CO2 emissions

Lowest

0.4 - 1.0kg

CO2 emissions

1.2 - 2.5kg

CO2 emissions

-

CO2 emissions

Deutsche Bahn

Most popular train company

FlixBus

Most popular bus company

Lufthansa

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Prague to Frankfurt am Main is a bus with an average price of $45.

This is compared to other travel options from Prague to Frankfurt am Main:

A bus is $65 less than a train for this route with tickets for a train from Prague to Frankfurt am Main costing on average $110.

A bus is $293 less than a flight for this route with tickets for a flight from Prague to Frankfurt am Main costing on average $339.

The fastest way to travel from Prague to Frankfurt am Main is by flight with an average journey time of 4h 53m.

Other travel options to Frankfurt am Main take longer:

Train takes on average 7h 43m.

Bus takes on average 8h 11m.

It's helpful to compare your options as there are 3 ways to travel between Prague and Frankfurt am Main including taking a train, bus, and flight.
We recommend using the train as it is the most popular way to get from Prague to Frankfurt am Main among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.

Tickets start at around $110 compared to roughly $110 in fuel and tolls — a saving of about $0.21. The journey takes 7h 13m versus 5h 1m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.

Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.

Travel options
from Prague to Frankfurt am Main

How to get from Prague to Frankfurt am Main by train, bus or flight.

Our recommendation

bus

The best way to travel from Prague to Frankfurt am Main is by taking a bus because it’s the best combination of price and speed.

  • FlixBusFlixBus
    4:15 PM8h05
    Praha, ÚAN Florenc
    12:20 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
    $421One-way
    0 transfers

Cheapest

  • FlixBusFlixBus
    4:15 PM8h05
    Praha, ÚAN Florenc
    12:20 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)
    $421One-way
    0 transfers

Fastest

  • Condor FlugdienstDE4406
    8:40 AM1h00
    Prague Vaclav Havel Airport
    9:40 AMFrankfurt am Main Airport
    $1791One-way
    0 transfers

Other options

  • Deutsche BahnEX 354 · 3576 · ICE 526
    1:35 PM7h44
    Prague hlavní nádraží
    9:19 PMFrankfurt Airport long-distance station
    $681One-way
    2 transfers
  • Deutsche BahnEX 354 · 3576 · ICE 526
    1:35 PM7h27
    Prague hlavní nádraží
    9:02 PMFrankfurt (Main) Hbf
    $731One-way
    2 transfers
  • Deutsche BahnEX 362 · 3560 · ICE 722
    5:35 AM7h27
    Prague hlavní nádraží
    1:02 PMFrankfurt (Main) Hbf
    $821One-way
    2 transfers
  • Infobus7457083
    4:30 AM8h05
    Prague
    12:35 PMFrankfurt am Main
    $421One-way
    0 transfers
  • FlixBusFlixBus
    9:10 AM7h35
    Praha, Na Knížecí
    4:45 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
    $451One-way
    0 transfers
  • FlixBusFlixBus
    4:15 PM7h35
    Praha, ÚAN Florenc
    11:50 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)
    $451One-way
    0 transfers
  • LufthansaLH1395
    11:55 AM1h10
    Prague Vaclav Havel Airport
    1:05 PMFrankfurt am Main Airport
    $1141One-way
    0 transfers
  • LufthansaLH1397
    2:40 PM1h10
    Prague Vaclav Havel Airport
    3:50 PMFrankfurt am Main Airport
    $1141One-way
    0 transfers
  • LufthansaLH1393
    9:10 AM1h10
    Prague Vaclav Havel Airport
    10:20 AMFrankfurt am Main Airport
    $1141One-way
    0 transfers

Find all the dates and times for this journey by train, bus, flight, and ferry .

Compare prices and tickets Prices for trains, buses and flights

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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How to get from Prague to Frankfurt am Main

The Best Way According to our Users

If you want to travel from Prague to Frankfurt am Main there are several options available to you. For this route, however, 74,41% of our customers choose the bus as their preferred method of transportation. Nowadays, traveling by bus is a relaxing and entertaining experience. Most bus companies offer different on-board services; ranging from "welcome drinks" to free wi-fi or personal entertainment. For this reason, the bus is often chosen as the best way to get from Prague to Frankfurt am Main. Bus companies normally offer comfortable journeys for reasonable prices, and if you choose to travel on a night bus you can even save the money of one night in a hotel. For that reason, the bus is most likely the cheapest way to get to your destination.

Search on Omio to find cheap tickets from Prague to Frankfurt am Main. It’s easy to find the most attractive prices and choose your preferred route for your journey. Book on web or app, and travel with your mobile ticket —without the stress of printing your ticket.

More than 1,000 travel companies trust us to sell their tickets all in one place.

Trenitalia
Easyjet
Deutsche Bahn
SNCF

FAQs: Travel from Prague to Frankfurt am Main

Travel to Frankfurt am Main easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Frankfurt am Main.

FAQs
There are 3 options to travel between Prague and Frankfurt am Main including taking a train, bus, and flight.
The cheapest way to travel from Prague to Frankfurt am Main is a bus with an average price of $45.

This is compared to other travel options from Prague to Frankfurt am Main:

A bus is $65 less than a train for this route with tickets for a train from Prague to Frankfurt am Main costing on average $110.

A bus is $293 less than a flight for this route with tickets for a flight from Prague to Frankfurt am Main costing on average $339.

The fastest way to travel from Prague to Frankfurt am Main is by flight with an average journey time of 4h 53m.

Other travel options to Frankfurt am Main take longer:

Train takes on average 7h 43m.

Bus takes on average 8h 11m.

The distance from Prague to Frankfurt am Main is approximately 254 miles (409 km).
The average frequency per day from Prague to Frankfurt am Main is:
  • Around 56 flights per day.
  • Around 28 buses per day.
  • Around 17 trains per day.

However, we recommend checking specific travel dates for your route between Prague and Frankfurt am Main as scheduled services by train, bus, and flight can vary by season or day of the week.

These are the most popular departure and arrival points from Prague to Frankfurt am Main:
  • Flights mostly depart from Prague Vaclav Havel Airport and arrive in Frankfurt am Main Airport.
  • Trains mostly depart from Prague hlavní nádraží and arrive in Frankfurt (Main) Hbf.
  • Buses mostly depart from Praha, ÚAN Florenc and arrive in Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof).
If finding a good deal is your main consideration for your trip from Prague to Frankfurt am Main, then we'll help you find the best value travel companies for you:
  • Travel with Lufthansa, Condor Flugdienst, Air Dolomiti, Lot Polish Airlines, Austrian Airlines, KLM, Lufthansa Cityline, KLM Cityhopper, Brussels Airlines, Qatar Airways, tarom, Croatia Airlines, Air Baltic, Helvetic Airways, British Airways, Cityjet, Edelweiss Air, Swiss, Air Serbia, TAP Portugal to go to Frankfurt am Main by flight.
  • Travel with Deutsche Bahn, České dráhy, Leo Express, Intercity to go to Frankfurt am Main by train.
  • Travel with FlixBus, Infobus, BlaBlaCar Bus, KLR to go to Frankfurt am Main by bus.
Yes, there are direct services available from Prague to Frankfurt am Main with the following travel companies:
  • 8 direct flights per day with Lufthansa, Condor Flugdienst, Air Dolomiti.
  • 0 direct trains per day with Leo Express.
  • 13 direct buses per day with FlixBus, Infobus, BlaBlaCar Bus, KLR.
Omio customers who travel from Prague to Frankfurt am Main often also extend their vacation to go to Paris, London, Berlin, Barcelona, Amsterdam. Omio can help you plan your trip by finding the best connections between Frankfurt am Main and these popular destinations at a great price.
Most travelers need at least three days in Frankfurt am Main to see the main sights at a comfortable pace. If you want day trips or a slower itinerary, consider adding extra time.
In Frankfurt am Main, visitors can enjoy panoramic views from the Main Tower and explore the vibrant Kleinmarkthalle for a variety of foods. The Senckenberg Natural History Museum offers fascinating dinosaur fossils, while a walk along the River Main provides scenic vistas. Shop at the lively Zeil or visit the Römer, a historic city hall. Art enthusiasts can explore the Städel Museum, while nature lovers will appreciate the Palmengarten. Delve into literary history at the Goethe House and admire the Gothic architecture of Frankfurt Cathedral.
Typically, spending 2 to 3 days in Frankfurt am Main is sufficient to explore its main attractions, such as the Römer, Städel Museum, and Palmengarten, while also enjoying the city's vibrant dining and shopping scenes.
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