Travel Information
Compare train and bus for Amsterdam to Karlsruhe
Omio recommends booking the train as it is the most popular option from Amsterdam to Karlsruhe among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €47 For those with little time, consider booking a train, which has an average total journey time of 6h 0m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of €47, while a train costs an average of €107.
Distance: 278 miles (448 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
€107 Average price | €47 Average price Cheapest | €104 Average price (fuel + tolls) |
6h 0m Average total duration Fastest 5h 30m Onboard + 30m Additional time* | 10h 45m Average total duration 10h 15m Onboard + 30m Additional time* | 5h 37m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Amsterdam to Karlsruhe
Compare the available ways to get from Amsterdam to Karlsruhe, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Amsterdam to Karlsruhe:
A bus is €60 less than a train for this route with tickets for a train from Amsterdam to Karlsruhe costing on average €107.
Other travel options to Karlsruhe take longer:
Bus takes on average 10h 45m.
You'll arrive about 7m sooner (5h 30m by train vs 5h 37m by car). Tickets start at around €107 compared to roughly €104 in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
Travel optionsfrom Amsterdam to Karlsruhe
How to get from Amsterdam to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Amsterdam to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
FlixBus8:50 PM 8h00 Amsterdam, Piarcoplein (Amsterdam Sloterdijk) 4:50 AM Karlsruhe Hbf €35 1 One-way 0 transfers
Cheapest
FlixBus8:50 PM 8h00 Amsterdam, Piarcoplein (Amsterdam Sloterdijk) 4:50 AM Karlsruhe Hbf €35 1 One-way 0 transfers
Fastest
LH1003+
ICE 1037:30 AM 3h29 Amsterdam Airport Schiphol 10:59 AM Karlsruhe Hbf €281 1 One-way 1 transfer
Other options
IC 3561 · 20093 · ICE 205 · S114:56 PM 6h18 Amsterdam Zuid 11:14 PM Karlsruhe Europaplatz/Post Galerie (Kaiserstraße) €42 1 One-way 3 transfers
IC 60403 · STR 38:03 PM 8h31 Amsterdam Centraal 4:34 AM Europaplatz/Post Galerie (Karlstraße) €42 1 One-way 1 transfer
ICE 221 · ICE 617 · ICE 677 · S116:38 PM 5h36 Amsterdam Centraal 12:14 AM Karlsruhe Europaplatz/Post Galerie (Kaiserstraße) €49 1 One-way 3 transfers
FlixBus4:50 PM 11h00 Schiphol, Airport Terminal 1 3:50 AM Karlsruhe Hbf €35 1 One-way 0 transfers
FlixBus4:30 PM 11h20 Amsterdam, Piarcoplein (Amsterdam Sloterdijk) 3:50 AM Karlsruhe Hbf €35 1 One-way 0 transfers
FlixBus9:00 AM 9h05 Amsterdam, Piarcoplein (Amsterdam Sloterdijk) 6:05 PM Karlsruhe Hbf €36 1 One-way 0 transfers
KL1819+
ICE 20512:30 PM 10h30 Amsterdam Airport Schiphol 11:00 PM Karlsruhe Hbf €228 1 One-way 1 transfer
KL1819+
ICE 20312:30 PM 8h30 Amsterdam Airport Schiphol 9:00 PM Karlsruhe Hbf €242 1 One-way 1 transfer
KL1815+
ICE 1078:30 AM 6h31 Amsterdam Airport Schiphol 3:01 PM Karlsruhe Hbf €243 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Amsterdam to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Amsterdam to Karlsruhe.

This is compared to other travel options from Amsterdam to Karlsruhe:
A bus is €60 less than a train for this route with tickets for a train from Amsterdam to Karlsruhe costing on average €107.
Other travel options to Karlsruhe take longer:
Bus takes on average 10h 45m.
- Around 6 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between Amsterdam and Karlsruhe as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Amsterdam Centraal and arrive in Karlsruhe Hbf.
- Buses mostly depart from Amsterdam, Piarcoplein (Amsterdam Sloterdijk) and arrive in Karlsruhe Hbf.
- Travel with Deutsche Bahn, VIAS Rail GmbH, Hessische Landesbahn to go to Karlsruhe by train.
- Travel with FlixBus, BlaBlaCar Bus to go to Karlsruhe by bus.
- 5 direct buses per day with FlixBus.
Travelling from Amsterdam to Karlsruhe: related information
Here are some other resources that might have the information you need
