Travel Information
Compare train and bus for Florence to Karlsruhe
Omio recommends booking the bus as it is the most popular option from Florence to Karlsruhe among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $70 For those with little time, consider booking a train, which has an average total journey time of 9h 29m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.2 - 0.6kg. Average ticket prices depend on the travel mode: a bus costs an average of $70, while a train costs an average of $249.
Distance: 386 miles (622 km)
Compare bus with
Most popular Bus | Train |
|---|---|
$70 Average price Cheapest | $249 Average price |
13h 50m Average total duration 13h 20m Onboard + 30m Additional time* | 9h 29m Average total duration Fastest 8h 59m Onboard + 30m Additional time* |
0.6 - 1.6kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Florence to Karlsruhe
How to get from Florence to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Florence to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
FlixBus8:00 PM15h10Scandicci, Villa Costanza (Florence)11:10 AMKarlsruhe Hbf$421One-way0 transfers
Cheapest
FlixBus8:00 PM15h10Scandicci, Villa Costanza (Florence)11:10 AMKarlsruhe Hbf$421One-way0 transfers
Fastest
EN8853+
ICE 10710:10 AM4h51Florence Peretola Airport3:01 PMKarlsruhe Hbf$8511One-way1 transfer
Other options
FlixBus · FlixBus · FlixBus4:55 AM19h05Firenze, Piazzale Montelungo12:00 AMKarlsruhe Hbf$891One-way2 transfers
FlixBus · FlixBus · FlixBus2:15 AM16h55Firenze, Piazzale Montelungo7:10 PMKarlsruhe Hbf$911One-way2 transfers
FlixBus · FlixBus4:35 AM16h25Scandicci, Villa Costanza (Florence)9:00 PMKarlsruhe Hbf$911One-way1 transfer
KL1654 · KL1821+
ICE 615 · ICE 37912:40 PM9h19Florence Peretola Airport9:59 PMKarlsruhe Hbf$2941One-way3 transfers
KL1654 · KL1821+
ICE 20512:40 PM10h19Florence Peretola Airport10:59 PMKarlsruhe Hbf$2941One-way2 transfers
KL1652 · KL1821+
ICE 615 · ICE 37911:20 AM10h39Florence Peretola Airport9:59 PMKarlsruhe Hbf$2941One-way3 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Florence to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Florence to Karlsruhe.

This is compared to other travel options from Florence to Karlsruhe:
A bus is $179 (€146) less than a train for this route with tickets for a train from Florence to Karlsruhe costing on average $249 (€204).
Other travel options to Karlsruhe take longer:
Bus takes on average 13h 50m.
- Around 15 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Florence and Karlsruhe as scheduled services by train and bus can vary by season or day of the week.
- Buses mostly depart from Scandicci, Villa Costanza (Florence) and arrive in Karlsruhe Hbf.
- Travel with Trenitalia, Frecciarossa to go to Karlsruhe by train.
- Travel with FlixBus, Infobus, BlaBlaCar Bus to go to Karlsruhe by bus.
- 1 direct buses per day with FlixBus, Infobus.
Travelling from Florence to Karlsruhe: related information
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