Travel Information
Compare bus for Rome to Karlsruhe
Omio recommends booking the bus as it is the most popular option from Rome to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from $57. For those with little time consider booking a bus which can get you there in 17h 45m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of $57, and a bus costs an average of $57.
Distance: 529 miles (852 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
$79 Average price Cheapest | $336 Average price (fuel + tolls) |
18h 15m Average total duration Fastest 17h 45m Onboard + 30m Additional time* | 10h 50m Average total duration (door-to-door) |
0.9 - 2.1kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Rome to Karlsruhe
How to get from Rome to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Rome to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
FlixBus4:35 PM18h35Roma, Autostazione Tiburtina11:10 AMKarlsruhe Hbf$561One-way0 transfers
Cheapest
FlixBus4:35 PM18h35Roma, Autostazione Tiburtina11:10 AMKarlsruhe Hbf$561One-way0 transfers
Fastest
DE4186+
ICE 2034:40 PM4h19Rome Leonardo da Vinci Fiumicino Airport8:59 PMKarlsruhe Hbf$1971One-way1 transfer
Other options
FlixBus · FlixBus1:00 PM20h45Roma, Autostazione Tiburtina9:45 AMKarlsruhe Hbf$821One-way1 transfer
FlixBus · FlixBus10:55 PM20h40Roma, Autostazione Tiburtina7:35 PMKarlsruhe Hbf$831One-way1 transfer
FlixBus · FlixBus+
FlixTrain5:00 PM22h26Roma, Autostazione Tiburtina3:26 PMKarlsruhe Hbf$841One-way2 transfers
ICE 205+
EC29921:00 PM9h59Rome Leonardo da Vinci Fiumicino Airport10:59 PMKarlsruhe Hbf$941One-way1 transfer
ICE 203+
EC29921:00 PM7h59Rome Leonardo da Vinci Fiumicino Airport8:59 PMKarlsruhe Hbf$981One-way1 transfer
ICE 613 · ICE 377+
EC29921:00 PM6h59Rome Leonardo da Vinci Fiumicino Airport7:59 PMKarlsruhe Hbf$1041One-way2 transfers
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FAQs: Travel from Rome to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Rome to Karlsruhe.

- Around 13 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Rome and Karlsruhe as scheduled services by bus can vary by season or day of the week.
- Buses mostly depart from Roma, Autostazione Tiburtina and arrive in Karlsruhe Hbf.
- Travel with FlixBus, Marino Autolinee to go to Karlsruhe by bus.
- 1 direct buses per day with FlixBus.
Travelling from Rome to Karlsruhe: related information
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