4.9
4.6
Travel Information
Compare bus for Rome to Karlsruhe
Omio recommends booking the bus as it is the most popular option from Rome to Karlsruhe among Omio's users. If you are prioritising price, take the flight, with an average ticket price of €69 For those with little time, consider booking a flight, which has an average total journey time of 5h 51m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.9 - 2.1kg. Average ticket prices depend on the travel mode: a flight costs an average of €69, while a bus costs an average of €97.
Distance: 529 miles (852 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
€97 Average price | €69 Average price Cheapest | €278 Average price (fuel + tolls) |
18h 14m Average total duration 17h 44m Onboard + 30m Additional time* | 5h 51m Average total duration Fastest 3h 51m Onboard + 2h 0m Additional time* | 10h 50m Average total duration (door-to-door) |
0.9 - 2.1kg CO2 emissions Lowest | 2.6 - 5.1kg CO2 emissions | - CO2 emissions |
 Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Rome to Karlsruhe
Compare the available ways to get from Rome to Karlsruhe, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Rome to Karlsruhe:
A flight is €29 less than a bus for this route with tickets for a bus from Rome to Karlsruhe costing on average €97.
Other travel options to Karlsruhe take longer:
Bus takes on average 18h 14m.
Tickets start at around €97 compared to roughly €278 in fuel and tolls — a saving of about €182. The journey takes 17h 44m versus 10h 50m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
Travel optionsfrom Rome to Karlsruhe
How to get from Rome to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Rome to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
- FlixBus
4:35 PM 18h35 Roma, Autostazione Tiburtina 11:10 AM Karlsruhe Hbf €60 1 One-way 0 transfers
Cheapest
- FlixBus
4:35 PM 18h35 Roma, Autostazione Tiburtina 11:10 AM Karlsruhe Hbf €60 1 One-way 0 transfers
Fastest
LH2331:30 PM 1h55 Rome Leonardo da Vinci Fiumicino Airport 3:25 PM Frankfurt am Main Airport €475 1 One-way 0 transfers
Other options
- FlixBus · FlixBus
1:00 PM 20h45 Roma, Autostazione Tiburtina 9:45 AM Karlsruhe Hbf €80 1 One-way 1 transfer - FlixBus · FlixBus+
FlixTrain5:00 PM 22h26 Roma, Autostazione Tiburtina 3:26 PM Karlsruhe Hbf €81 1 One-way 2 transfers - FlixBus · FlixBus
9:00 PM 19h30 Roma, Autostazione Tiburtina 4:30 PM Karlsruhe Hbf €81 1 One-way 1 transfer
U22993+
ICE 1096:40 AM 10h19 Rome Leonardo da Vinci Fiumicino Airport 4:59 PM Karlsruhe Hbf €178 1 One-way 1 transfer- U22993+ICE 107
6:40 AM 8h19 Rome Leonardo da Vinci Fiumicino Airport 2:59 PM Karlsruhe Hbf €180 1 One-way 1 transfer - U22993+ICE 915 · ICE 71
6:40 AM 4h43 Rome Leonardo da Vinci Fiumicino Airport 11:23 AM Karlsruhe Hbf €183 1 One-way 2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Rome to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Rome to Karlsruhe.
This is compared to other travel options from Rome to Karlsruhe:
A flight is €29 less than a bus for this route with tickets for a bus from Rome to Karlsruhe costing on average €97.
Other travel options to Karlsruhe take longer:
Bus takes on average 18h 14m.
- Around 12 buses per day.
- Around 2 flights per day.
However, we recommend checking specific travel dates for your route between Rome and Karlsruhe as scheduled services by bus can vary by season or day of the week.
- Flights mostly depart from Rome Leonardo da Vinci Fiumicino Airport and arrive in Karlsruhe/Baden-Baden Airport.
- Trains mostly depart from Rome Termini and arrive in Karlsruhe Hbf.
- Buses mostly depart from Roma, Autostazione Tiburtina and arrive in Karlsruhe Hbf.
- Travel with FlixBus, Marino Autolinee to go to Karlsruhe by bus.
- Travel with Malta Air, Ryanair to go to Karlsruhe by flight.
- 1 direct buses per day with FlixBus.
Travelling from Rome to Karlsruhe: related information
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