Travel optionsfrom Rome to Karlsruhe
How to get from Rome to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Rome to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
FlixBus4:35 PM18h35Roma, Autostazione Tiburtina11:10 AMKarlsruhe Hbfkr6921One-way0 transfers
Cheapest
FlixBus4:35 PM18h35Roma, Autostazione Tiburtina11:10 AMKarlsruhe Hbfkr6921One-way0 transfers
Fastest
FlixBus · FlixBus10:40 AM17h05Roma, Autostazione Tiburtina3:45 AMKarlsruhe Hbfkr9871One-way1 transfer
Other options
FlixBus · FlixBus · FlixBus5:25 PM18h45Roma, Autostazione (Metro Anagnina)12:10 PMKarlsruhe Hbfkr8831One-way2 transfers
FlixBus · FlixBus8:00 PM19h00Roma, Autostazione Tiburtina3:00 PMKarlsruhe Hbfkr8911One-way1 transfer
FlixBus · FlixBus9:25 AM17h45Roma, Autostazione Tiburtina3:10 AMKarlsruhe Hbfkr9191One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Travel Information
Compare bus for Rome to Karlsruhe
Omio recommends booking the bus as it is the most popular option from Rome to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from kr374. For those with little time consider booking a bus which can get you there in 17h 45m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of kr374, and a bus costs an average of kr374.
Distance: 529 miles (852 km)
Compare bus with
Most popular Bus | Driving |
|---|---|
kr517 Average price Cheapest | kr2193 Average price (fuel + tolls) |
18h 15m Average total duration Fastest 17h 45m Onboard + 30m Additional time* | 10h 50m Average total duration (door-to-door) |
0.9 - 2.1kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare prices and tickets Prices for trains, buses and flights
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Aug 03
Aug 04
Aug 05
Aug 06
Aug 07
Aug 08
Aug 09
Aug 10
Aug 11
Aug 12
Aug 13
Aug 14
Aug 15
Aug 16
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Rome to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Rome to Karlsruhe.

- Around 13 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Rome and Karlsruhe as scheduled services by bus can vary by season or day of the week.
- Buses mostly depart from Roma, Autostazione Tiburtina and arrive in Karlsruhe Hbf.
- Travel with FlixBus, Marino Autolinee to go to Karlsruhe by bus.
- 1 direct buses per day with FlixBus.
Travelling from Rome to Karlsruhe: related information
Here are some other resources that might have the information you need
