Travel Information
Compare bus for Rome to Karlsruhe
Omio recommends booking the bus as it is the most popular option from Rome to Karlsruhe among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €66 For those with little time, consider booking a bus, which has an average total journey time of 18h 20m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.9 - 2.1kg. Average ticket prices depend on the travel mode: a bus costs an average of €66, while a bus costs an average of €66.
Distance: 529 miles (852 km)
Compare bus with
Most popular Bus |
|---|
€66 Average price Cheapest |
18h 20m Average total duration Fastest 17h 50m Onboard + 30m Additional time* |
0.9 - 2.1kg CO2 emissions Lowest |
![]() Most popular bus company |
Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Rome to Karlsruhe
How to get from Rome to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Rome to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
FlixBus4:35 PM18h35Roma, Autostazione Tiburtina11:10 AMKarlsruhe Hbf€571One-way0 transfers
Cheapest
FlixBus4:35 PM18h35Roma, Autostazione Tiburtina11:10 AMKarlsruhe Hbf€571One-way0 transfers
Fastest
FR 7174 · FR 820711:25 AM11h25Rome Leonardo da Vinci Fiumicino Airport10:50 PMKarlsruhe/Baden-Baden Airport€2461One-way1 transfer
Other options
FlixBus · FlixBus+
FlixTrain8:00 PM18h21Roma, Autostazione Tiburtina2:21 PMKarlsruhe Hbf€621One-way2 transfers
FlixBus · FlixBus+
FlixTrain12:45 PM21h38Roma, Autostazione (Metro Anagnina)10:23 AMKarlsruhe Hbf€741One-way2 transfers
FlixBus · FlixBus8:00 PM19h00Roma, Autostazione Tiburtina3:00 PMKarlsruhe Hbf€761One-way1 transfer
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FAQs: Travel from Rome to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Rome to Karlsruhe.

- Around 13 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Rome and Karlsruhe as scheduled services by bus can vary by season or day of the week.
- Buses mostly depart from Roma, Autostazione Tiburtina and arrive in Karlsruhe Hbf.
- Travel with FlixBus, Marino Autolinee to go to Karlsruhe by bus.
- 1 direct buses per day with FlixBus.
Travelling from Rome to Karlsruhe: related information
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