Travel Information from Rome to Karlsruhe
| 528 miles (852 km) | |
| Train or bus | |
| $40 - $285 | |
| Bus • $40 (€36) • 18 h 5 min | |
| Train • $285 (€257) • 9 h 39 min | |
| FlixBus or Frecciarossa |
Travel 528 miles (852 km) by train or bus between Rome and Karlsruhe. The most popular travel companies which serve this journey are FlixBus or Frecciarossa among others. Travelers can even take a direct bus or train from Rome to Karlsruhe.
Travel optionsfrom Rome to Karlsruhe
How to get from Rome to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Rome to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
FlixBusCheapest
FlixBusFastest
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ICE 107Other options
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
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ICE 107
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ICE 517 · ICE 279Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Rome to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Rome to Karlsruhe.

There are 2 options to travel between Rome and Karlsruhe including taking a train or bus.
The cheapest way to go to Karlsruhe from Rome is by taking a bus, which costs on average $40 (€36).
This is compared to other ways of getting from Rome to Karlsruhe:
Taking a bus costs $244 (€221) less than taking a train, which average ticket prices of $285 (€257).
The fastest way from Rome to Karlsruhe is by train with an average journey time of 9 h 39 min.
There are alternative travel options to Karlsruhe that take longer:
Bus takes 18 h 5 min on average.
The Rome to Karlsruhe distance is around 528 miles (852 km).
The average frequency per day from Rome to Karlsruhe is:
- Around 1 bus per day.
- Around 1 train per day.
However, we recommend checking specific travel dates for your journey between Rome and Karlsruhe as scheduled services by train or bus can vary by season or day of the week.
These are the most popular departure and arrival points from Rome to Karlsruhe:
- Buses most often depart from Rome at Roma, Autostazione Tiburtina and arrive in Karlsruhe at Karlsruhe Hbf.
Omio works with many trusted partners that can help you travel the best way from Rome to Karlsruhe:
- You can take a bus from Rome to Karlsruhe with FlixBus. Cheap tickets can be found for $40 (€36) with FlixBus from Rome to Karlsruhe.
- You can go to Karlsruhe from Rome by train with Frecciarossa. You'll see cheap train tickets for $285 (€257) with Frecciarossa from Rome to Karlsruhe on Omio.
Yes, there are direct routes from Rome to Karlsruhe with the following travel companies:
- You'll find 1 direct bus a day to Karlsruhe with FlixBus.
Direct services to Karlsruhe tend to save you time and add more convenience as you won't need to transfer at another stop in between, so it's worth paying attention to before booking tickets for your route.
Travelling from Rome to Karlsruhe: related information
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