Travel Information
Compare train and bus for Rome to Karlsruhe
Omio recommends booking the bus as it is the most popular option from Rome to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from €49. For those with little time consider booking a train which can get you there in 9h 39m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.1kg. The ticket price range depends on the travel mode: a bus costs an average of €49, and a train costs an average of €229.
Distance: 529 miles (852 km)
Compare bus with
Most popular Bus | Train |
|---|---|
€83 Average price Cheapest | €229 Average price |
17h 55m Average total duration 17h 25m Onboard + 30m Additional time* | 10h 9m Average total duration Fastest 9h 39m Onboard + 30m Additional time* |
0.9 - 2.1kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Rome to Karlsruhe
How to get from Rome to Karlsruhe by train, bus or flight.
Our recommendation
The best way to travel from Rome to Karlsruhe is by taking a bus because it’s the best combination of price and speed.
FlixBusCheapest
FlixBusFastest
U22993+
ICE 915 · ICE 71Other options
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
U22993+
ICE 107
U22993+
ICE 109
LH233+
ICE 203Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Rome to Karlsruhe
Travel to Karlsruhe easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Rome to Karlsruhe.

This is compared to other travel options from Rome to Karlsruhe:
A bus is $226 (€180) less than a train for this route with tickets for a train from Rome to Karlsruhe costing on average $288 (€229).
Other travel options to Karlsruhe take longer:
Bus takes on average 17h 5m.
- Around 12 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Rome and Karlsruhe as scheduled services by train and bus can vary by season or day of the week.
- Buses mostly depart from Roma, Autostazione Tiburtina and arrive in Karlsruhe Hbf.
- Travel with Frecciarossa to go to Karlsruhe by train.
- Travel with FlixBus to go to Karlsruhe by bus.
- 1 direct buses per day with FlixBus.
Travelling from Rome to Karlsruhe: related information
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