Travel Information
Compare train, bus, and flight for Frankfurt am Main to Palermo
Omio recommends booking the flight as it is the most popular option from Frankfurt am Main to Palermo among Omio's users. If you are prioritising price take the bus with prices starting from $96. For those with little time consider booking a flight which can get you there in 2h 59m. The ticket price range depends on the travel mode: a bus costs an average of $96, and a train costs an average of $430.
Distance: 860 miles (1385 km)
Compare flight with
Most popular Flight | Bus | Train | Driving |
|---|---|---|---|
$240 Average price | $163 Average price Cheapest | $430 Average price | $320 Average price (fuel + tolls) |
5h 59m Average total duration Fastest 2h 59m Onboard + 3h 0m Additional time* | 33h 7m Average total duration 32h 37m Onboard + 30m Additional time* | 24h 28m Average total duration 23h 58m Onboard + 30m Additional time* | 22h 1m Average total duration (door-to-door) |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Frankfurt am Main to Palermo:
A bus is $76 (€62) less than a flight for this route with tickets for a flight from Frankfurt am Main to Palermo costing on average $240 (€195).
A bus is $266 (€217) less than a train for this route with tickets for a train from Frankfurt am Main to Palermo costing on average $430 (€350).
Other travel options to Palermo take longer:
Train takes on average 23h 58m.
Bus takes on average 32h 37m.
Travel optionsfrom Frankfurt am Main to Palermo
How to get from Frankfurt am Main to Palermo by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Palermo is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus · FlixBus1:40 AM37h35Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)$1601One-way2 transfers
Cheapest
FlixBus · FlixBus · FlixBus1:40 AM37h35Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)$1601One-way2 transfers
Fastest
LH3222:35 PM2h20Frankfurt am Main Airport4:55 PMPalermo Airport$1971One-way0 transfers
Other options
FlixBus · FlixBus · FlixBus1:15 AM38h00Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)$1671One-way2 transfers
FlixTrain+
FlixBus · FlixBus · FlixBus8:05 PM38h55Frankfurt South station11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$1681One-way3 transfers
FlixBus · FlixBus · FlixBus10:45 PM36h15Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$1761One-way2 transfers
AZ407 · AZ17896:25 PM4h05Frankfurt am Main Airport10:30 PMPalermo Airport$1671One-way1 transfer
AZ407 · AZ17836:25 PM4h40Frankfurt am Main Airport11:05 PMPalermo Airport$1671One-way1 transfer
LH108 · LH19161:15 PM4h05Frankfurt am Main Airport5:20 PMPalermo Airport$2381One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jun 19
Jun 20
Jun 21
Jun 22
Jun 23
Jun 24
Jun 25
Jun 26
Jun 27
Jun 28
Jun 29
Jun 30
Jul 01
Jul 02
Jul 03
Jul 04
Jul 05
Jul 06
Jul 07
Jul 08
Jul 09
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Frankfurt am Main to Palermo
Travel to Palermo easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Palermo.

This is compared to other travel options from Frankfurt am Main to Palermo:
A bus is $76 (€62) less than a flight for this route with tickets for a flight from Frankfurt am Main to Palermo costing on average $240 (€195).
A bus is $266 (€217) less than a train for this route with tickets for a train from Frankfurt am Main to Palermo costing on average $430 (€350).
Other travel options to Palermo take longer:
Train takes on average 23h 58m.
Bus takes on average 32h 37m.
- Around 46 flights per day.
- Around 5 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Palermo as scheduled services by train, bus, and flight can vary by season or day of the week.
- Buses mostly depart from Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) and arrive in Palermo, Via Tommaso Fazello (Terminal Bus).
- Flights mostly depart from Frankfurt am Main Airport and arrive in Palermo Airport.
- Travel with Malta Air, ITA, Lufthansa, Ryanair, Air Dolomiti, Austrian Airlines, Amelia, Swiss, Condor Flugdienst to go to Palermo by flight.
- Travel with Intercity Notte, Deutsche Bahn Intercity (DB IC) to go to Palermo by train.
- Travel with FlixBus, Infobus to go to Palermo by bus.
- 1 direct flights per day with Malta Air, Lufthansa, Ryanair, Condor Flugdienst.
- 0 direct buses per day with Infobus.
Travelling from Frankfurt am Main to Palermo: related information
Here are some other resources that might have the information you need


