Travel Information
Compare train, bus, and flight for Frankfurt am Main to Palermo
Omio recommends booking the flight as it is the most popular option from Frankfurt am Main to Palermo among Omio's users. If you are prioritising price take the bus with prices starting from $91. For those with little time consider booking a flight which can get you there in 2h 59m. The ticket price range depends on the travel mode: a bus costs an average of $91, and a train costs an average of $455.
Distance: 860 miles (1385 km)
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
$244 Average price | $160 Average price Cheapest | $478 Average price |
5h 59m Average total duration Fastest 2h 59m Onboard + 3h 0m Additional time* | 33h 6m Average total duration 32h 36m Onboard + 30m Additional time* | 24h 28m Average total duration 23h 58m Onboard + 30m Additional time* |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Travel optionsfrom Frankfurt am Main to Palermo
How to get from Frankfurt am Main to Palermo by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Palermo is by taking a flight because it’s the best combination of price and speed.
FR 6349Cheapest
FlixBus · FlixBus · FlixBusFastest
FR 6349Other options
FlixBus · FlixBus · FlixBus
FlixTrain+
FlixBus · FlixBus
FlixBus · FlixBus
KL1824+
KL1601+
KL3634
KL1824+
KL1601+
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KL3431Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Frankfurt am Main to Palermo
Travel to Palermo easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Palermo.

This is compared to other travel options from Frankfurt am Main to Palermo:
A flight is $68 (€55) less than a bus for this route with tickets for a bus from Frankfurt am Main to Palermo costing on average $91 (€75).
A flight is $431 (€352) less than a train for this route with tickets for a train from Frankfurt am Main to Palermo costing on average $455 (€371).
Other travel options to Palermo take longer:
Train takes on average 28h 57m.
Bus takes on average 33h 15m.
- Around 41 flights per day.
- Around 4 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Palermo as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Palermo Airport.
- Buses mostly depart from Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) and arrive in Palermo, Via Tommaso Fazello (Terminal Bus).
- Travel with Intercity Notte, Deutsche Bahn to go to Palermo by train.
- Travel with FlixBus, Infobus to go to Palermo by bus.
- Travel with ITA, KM Malta Airlines, Lufthansa, Ryanair, Air Dolomiti, Austrian Airlines, Amelia, SWISS, Condor to go to Palermo by flight.
- 1 direct flights per day with KM Malta Airlines, Condor.
Travelling from Frankfurt am Main to Palermo: related information
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