Travel Information
Compare train, bus, and flight for Frankfurt am Main to Palermo
Omio recommends booking the flight as it is the most popular option from Frankfurt am Main to Palermo among Omio's users. If you are prioritising price take the bus with prices starting from €94. For those with little time consider booking a flight which can get you there in 3h 4m. The ticket price range depends on the travel mode: a bus costs an average of €94, and a train costs an average of €376.
Distance: 860 miles (1385 km)
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
€169 Average price | €159 Average price Cheapest | €395 Average price |
6h 4m Average total duration Fastest 3h 4m Onboard + 3h 0m Additional time* | 33h 8m Average total duration 32h 38m Onboard + 30m Additional time* | 24h 28m Average total duration 23h 58m Onboard + 30m Additional time* |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Travel optionsfrom Frankfurt am Main to Palermo
How to get from Frankfurt am Main to Palermo by train, bus or flight.
Our recommendation
The best way to travel from Frankfurt am Main to Palermo is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBusCheapest
FlixBus · FlixBusFastest
AZ407 · AZ1783Other options
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus · FlixBus
AZ7289 · AZ1787
AZ7411 · AZ1771
AZ7291 · AZ1771Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Frankfurt am Main to Palermo
Travel to Palermo easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Frankfurt am Main to Palermo.

This is compared to other travel options from Frankfurt am Main to Palermo:
A flight is $78 (€62) less than a bus for this route with tickets for a bus from Frankfurt am Main to Palermo costing on average $119 (€94).
A flight is $433 (€343) less than a train for this route with tickets for a train from Frankfurt am Main to Palermo costing on average $475 (€376).
Other travel options to Palermo take longer:
Train takes on average 28h 57m.
Bus takes on average 33h 15m.
- Around 36 flights per day.
- Around 4 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Frankfurt am Main and Palermo as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Palermo Airport.
- Buses mostly depart from Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) and arrive in Palermo, Via Tommaso Fazello (Terminal Bus).
- Travel with ITA, Lufthansa, Ryanair, KM Malta Airlines, Air Dolomiti, Lufthansa Cityline, Amelia, SWISS, Condor, KLM to go to Palermo by flight.
- Travel with Intercity Notte, Deutsche Bahn to go to Palermo by train.
- Travel with FlixBus, Infobus to go to Palermo by bus.
- 1 direct flights per day with Lufthansa, KM Malta Airlines, Condor.
- 0 direct buses per day with Infobus.
Travelling from Frankfurt am Main to Palermo: related information
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