Travel Information
Compare bus, flight, and train for Lyon to Palermo
Omio recommends booking the flight as it is the most popular option from Lyon to Palermo among Omio's users. If you are prioritising price take the bus with prices starting from $98. For those with little time consider booking a flight which can get you there in 2h 41m. The ticket price range depends on the travel mode: a bus costs an average of $98, and a flight costs an average of $53.
Distance: 684 miles (1102 km)
Compare flight with
Most popular Flight | Bus | Train | Driving |
|---|---|---|---|
$265 Average price | $171 Average price Cheapest | $251 Average price | $319 Average price (fuel + tolls) |
5h 41m Average total duration Fastest 2h 41m Onboard + 3h 0m Additional time* | 28h 52m Average total duration 28h 22m Onboard + 30m Additional time* | 24h 41m Average total duration 24h 11m Onboard + 30m Additional time* | 19h 26m Average total duration (door-to-door) |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Lyon to Palermo:
A bus is $80 (€66) less than a train for this route with tickets for a train from Lyon to Palermo costing on average $251 (€207).
A bus is $94 (€78) less than a flight for this route with tickets for a flight from Lyon to Palermo costing on average $265 (€219).
Other travel options to Palermo take longer:
Train takes on average 24h 11m.
Bus takes on average 28h 22m.
Travel optionsfrom Lyon to Palermo
How to get from Lyon to Palermo by train, bus or flight.
Our recommendation
The best way to travel from Lyon to Palermo is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus10:50 AM28h25Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)$1631One-way1 transfer
Cheapest
FlixBus · FlixBus10:50 AM28h25Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)$1631One-way1 transfer
Fastest
FlixBus · FlixBus10:50 AM28h25Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)3:15 PMPalermo, Via Tommaso Fazello (Terminal Bus)$1631One-way1 transfer
Other options
FlixBus · FlixBus3:15 AM31h45Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$1851One-way1 transfer
FlixBus · FlixBus · FlixBus11:00 PM36h00Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)11:00 AMPalermo, Via Tommaso Fazello (Terminal Bus)$2181One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Lyon to Palermo
Travel to Palermo easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Palermo.

This is compared to other travel options from Lyon to Palermo:
A bus is $80 (€66) less than a train for this route with tickets for a train from Lyon to Palermo costing on average $251 (€207).
A bus is $94 (€78) less than a flight for this route with tickets for a flight from Lyon to Palermo costing on average $265 (€219).
Other travel options to Palermo take longer:
Train takes on average 24h 11m.
Bus takes on average 28h 22m.
- Around 20 flights per day.
- Around 3 buses per day.
- Around 1 trains per day.
However, we recommend checking specific travel dates for your route between Lyon and Palermo as scheduled services by bus, flight, and train can vary by season or day of the week.
- Flights mostly depart from Lyon Saint Exupery Airport and arrive in Palermo Airport.
- Trains mostly depart from Lyon Part Dieu and arrive in Palermo Centrale.
- Buses mostly depart from Lyon, Perrache Bus Station and arrive in Palermo, Via Tommaso Fazello (Terminal Bus).
- Travel with FlixBus, BlaBlaCar Bus to go to Palermo by bus.
- Travel with Intercity Notte to go to Palermo by train.
- Travel with easyJet, Volotea, Transavia France, Vueling, Air Dolomiti, Lufthansa Cityline, Lufthansa to go to Palermo by flight.
- 1 direct flights per day with easyJet, Volotea, Transavia France.
Travelling from Lyon to Palermo: related information
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