Travel Information
Compare bus, train, and flight for Lyon to Palermo
Omio recommends booking the flight as it is the most popular option from Lyon to Palermo among Omio's users. If you are prioritising price, take the train, with an average ticket price of €124 For those with little time, consider booking a flight, which has an average total journey time of 6h 33m. Average ticket prices depend on the travel mode: a train costs an average of €124, while a flight costs an average of €313.
Distance: 684 miles (1102 km)
Compare flight with
Most popular Flight | Bus | Train | Driving |
|---|---|---|---|
€313 Average price | €151 Average price | €124 Average price Cheapest | €265 Average price (fuel + tolls) |
6h 33m Average total duration Fastest 4h 33m Onboard + 2h 0m Additional time* | 28h 36m Average total duration 28h 6m Onboard + 30m Additional time* | 24h 21m Average total duration 23h 51m Onboard + 30m Additional time* | 19h 26m Average total duration (door-to-door) |
![]() Most popular airline | ![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Compare ways to travel from Lyon to Palermo
Compare the available ways to get from Lyon to Palermo, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Lyon to Palermo:
A train is €27 less than a bus for this route with tickets for a bus from Lyon to Palermo costing on average €151.
A train is €189 less than a flight for this route with tickets for a flight from Lyon to Palermo costing on average €313.
Other travel options to Palermo take longer:
Train takes on average 24h 21m.
Bus takes on average 28h 36m.
You'll arrive about 14h 53m sooner (4h 33m by flight vs 19h 26m by car). Tickets start at around €313 compared to roughly €265 in fuel and tolls — a bit more, but you get time back and avoid a long drive.
Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.
Travel optionsfrom Lyon to Palermo
How to get from Lyon to Palermo by train, bus or flight.
Our recommendation
The best way to travel from Lyon to Palermo is by taking a flight because it’s the best combination of price and speed.
VY8131 · VY61269:20 PM 11h20 Lyon Saint Exupery Airport 8:40 AM Palermo Airport €122 1 One-way 1 transfer
Cheapest
VY8131 · VY61269:20 PM 11h20 Lyon Saint Exupery Airport 8:40 AM Palermo Airport €122 1 One-way 1 transfer
Fastest
VY8129 · VY27244:40 PM 4h30 Lyon Saint Exupery Airport 9:10 PM Palermo Airport €242 1 One-way 1 transfer
Other options
FlixBus · FlixBus3:30 AM 31h30 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) €153 1 One-way 1 transfer
FlixBus · FlixBus · FlixBus11:00 PM 36h00 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) 11:00 AM Palermo, Via Tommaso Fazello (Terminal Bus) €187 1 One-way 2 transfers
FlixBus · FlixBus9:35 AM 29h40 Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) 3:15 PM Palermo, Via Tommaso Fazello (Terminal Bus) €194 1 One-way 1 transfer
LH236+
AZ1767+
LH459310:35 AM 9h15 Lyon Saint Exupery Airport 7:50 PM Palermo Airport €294 1 One-way 2 transfers
AF7367 · AF1404+
FR 49063:05 PM 8h00 Lyon Saint Exupery Airport 11:05 PM Palermo Airport €313 1 One-way 2 transfers
AF7365 · AF1404+
FR 49062:25 PM 8h40 Lyon Saint Exupery Airport 11:05 PM Palermo Airport €313 1 One-way 2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Lyon to Palermo
Travel to Palermo easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Palermo.

This is compared to other travel options from Lyon to Palermo:
A train is €27 less than a bus for this route with tickets for a bus from Lyon to Palermo costing on average €151.
A train is €189 less than a flight for this route with tickets for a flight from Lyon to Palermo costing on average €313.
Other travel options to Palermo take longer:
Train takes on average 24h 21m.
Bus takes on average 28h 36m.
- Around 65 flights per day.
- Around 4 trains per day.
- Around 3 buses per day.
However, we recommend checking specific travel dates for your route between Lyon and Palermo as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Lyon Saint Exupery Airport and arrive in Palermo Airport.
- Trains mostly depart from Lyon Part Dieu and arrive in Palermo Centrale.
- Buses mostly depart from Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) and arrive in Palermo, Via Tommaso Fazello (Terminal Bus).
- Travel with FlixBus to go to Palermo by bus.
- Travel with Air France, KLM, Lufthansa, ITA, Turkish Airlines, Malta Air, Vueling, Brussels Airlines, Lufthansa City Airlines, Austrian Airlines, easyJet, Transavia France, British Airways, Air Baltic, Swiss, Air Dolomiti, Volotea, CitizenPlane, Lufthansa Cityline, Helvetic Airways, Eurowings, KLM Cityhopper, Edelweiss Air to go to Palermo by flight.
- Travel with Intercity Notte, Intercity to go to Palermo by train.
- 1 direct flights per day with easyJet, Transavia France, Volotea, CitizenPlane.
Travelling from Lyon to Palermo: related information
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