Travel Information
Compare bus, train, and flight for Mannheim to Prague
Omio recommends booking the train as it is the most popular option from Mannheim to Prague among Omio's users. If you are prioritising price take the bus with prices starting from $32. For those with little time consider booking a flight which can get you there in 2h 2m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $32, and a flight costs an average of $157.
Distance: 267 miles (431 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$112 Average price | $56 Average price Cheapest | $213 Average price |
9h 40m Average total duration 9h 10m Onboard + 30m Additional time* | 7h 2m Average total duration 6h 32m Onboard + 30m Additional time* | 5h 2m Average total duration Fastest 2h 2m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | 1.3 - 2.6kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Mannheim to Prague
How to get from Mannheim to Prague by train, bus or flight.
Our recommendation
The best way to travel from Mannheim to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBus5:20 AM7h25Mannheim, ZOB (Heinrich-Von-Stephan-Straße)12:45 PMPraha, Na Knížecí$561One-way0 transfers
Cheapest
FlixBus5:20 AM7h25Mannheim, ZOB (Heinrich-Von-Stephan-Straße)12:45 PMPraha, Na Knížecí$561One-way0 transfers
Fastest
DE44073:00 PM1h00Frankfurt am Main Airport4:00 PMPrague Vaclav Havel Airport$2051One-way0 transfers
Other options
ICE 692 · IC 2443 · rj 3839:29 AM7h56Mannheim Hbf5:25 PMPrague hlavní nádraží$1541One-way2 transfers
ICE 774 · ICE 527 · 3565+
3578:03 AM8h18Mannheim Hbf4:21 PMPrague hlavní nádraží$1591One-way3 transfers
ICE 692 · IC 2443 · RJ 3839:29 AM7h56Mannheim Hbf5:25 PMPrague hlavní nádraží$1711One-way2 transfers
FlixBus5:20 AM7h45Mannheim, ZOB (Heinrich-Von-Stephan-Straße)1:05 PMPraha, ÚAN Florenc$561One-way0 transfers
FlixBus3:35 PM7h20Mannheim, ZOB (Heinrich-Von-Stephan-Straße)10:55 PMPraha, Na Knížecí$561One-way0 transfers
FlixBus3:35 PM7h35Mannheim, ZOB (Heinrich-Von-Stephan-Straße)11:10 PMPraha, ÚAN Florenc$561One-way0 transfers
ICE 1010+
DE440711:07 AM4h53Mannheim Hbf4:00 PMPrague Vaclav Havel Airport$2071One-way1 transfer
ICE 218+
DE44113:55 PM5h30Mannheim Hbf9:25 PMPrague Vaclav Havel Airport$2051One-way1 transfer
ICE 516+
DE44114:34 PM4h51Mannheim Hbf9:25 PMPrague Vaclav Havel Airport$2081One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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How to get from Mannheim to Prague
The Best Way According to our Users
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FAQs: Travel from Mannheim to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mannheim to Prague.

This is compared to other travel options from Mannheim to Prague:
A bus is $11 (€9) less than a train for this route with tickets for a train from Mannheim to Prague costing on average $43 (€35).
A bus is $125 (€100) less than a flight for this route with tickets for a flight from Mannheim to Prague costing on average $157 (€125).
Other travel options to Prague take longer:
Bus takes on average 7h 10m.
Train takes on average 7h 46m.
- Around 55 flights per day.
- Around 11 trains per day.
- Around 7 buses per day.
However, we recommend checking specific travel dates for your route between Mannheim and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Mannheim Hbf and arrive in Prague hlavní nádraží.
- Buses mostly depart from Mannheim, ZOB (Heinrich-Von-Stephan-Straße) and arrive in Praha, ÚAN Florenc.
- Travel with alex-Länderbahn und Vogtlandbahn-GmbH, Deutsche Bahn, České dráhy, ÖBB to go to Prague by train.
- Travel with FlixBus, BlaBlaCar to go to Prague by bus.
- Travel with Lufthansa, LOT Polish Airlines to go to Prague by flight.
- 0 direct trains per day with ÖBB.
- 6 direct buses per day with FlixBus, BlaBlaCar.
Travelling from Mannheim to Prague: related information
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