Travel Information
Compare bus and flight for Mannheim to Rome
Omio recommends booking the flight as it is the most popular option from Mannheim to Rome among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $130 For those with little time, consider booking a flight, which has an average total journey time of 5h 31m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 0.9 - 2.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $130, while a flight costs an average of $539.
Distance: 559 miles (900 km)
Compare flight with
Most popular Flight | Bus | Driving |
|---|---|---|
$539 Average price | $130 Average price Cheapest | $342 Average price (fuel + tolls) |
5h 31m Average total duration Fastest 3h 31m Onboard + 2h 0m Additional time* | 19h 14m Average total duration 18h 44m Onboard + 30m Additional time* | 12h 45m Average total duration (door-to-door) |
2.7 - 5.4kg CO2 emissions | 0.9 - 2.3kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Mannheim to Rome:
A bus is $408 (€343) less than a flight for this route with tickets for a flight from Mannheim to Rome costing on average $539 (€452).
Other travel options to Rome take longer:
Bus takes on average 19h 14m.
You'll arrive about 9h 14m sooner (3h 31m by flight vs 12h 45m by car). Tickets start at around $539 (€452) compared to roughly $342 (€287) in fuel and tolls — a bit more, but you get time back and avoid a long drive.
Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.
Travel optionsfrom Mannheim to Rome
How to get from Mannheim to Rome by train, bus or flight.
Our recommendation
The best way to travel from Mannheim to Rome is by taking a bus because it’s the best combination of price and speed.
FlixBus7:00 PM18h50Mannheim, ZOB (Heinrich-Von-Stephan-Straße)1:50 PMRoma, Autostazione Tiburtina$571One-way0 transfers
Cheapest
FlixBus7:00 PM18h50Mannheim, ZOB (Heinrich-Von-Stephan-Straße)1:50 PMRoma, Autostazione Tiburtina$571One-way0 transfers
Fastest
EW28826:10 AM1h35Stuttgart Airport7:45 AMRome Leonardo da Vinci Fiumicino Airport$1291One-way0 transfers
Other options
FlixBus · FlixBus · FlixBus2:45 PM21h30Mannheim, ZOB (Heinrich-Von-Stephan-Straße)12:15 PMRoma, Autostazione (Metro Anagnina)$1101One-way2 transfers
FlixBus · FlixBus2:45 PM18h45Mannheim, ZOB (Heinrich-Von-Stephan-Straße)9:30 AMRoma, Autostazione Tiburtina$1111One-way1 transfer
FlixBus · FlixBus7:00 PM20h05Mannheim, ZOB (Heinrich-Von-Stephan-Straße)3:05 PMRoma, Autostazione (Metro Anagnina)$1151One-way1 transfer
EW28866:25 PM1h35Stuttgart Airport8:00 PMRome Leonardo da Vinci Fiumicino Airport$1661One-way0 transfers
U229959:00 PM1h55Frankfurt am Main Airport10:55 PMRome Leonardo da Vinci Fiumicino Airport$1731One-way0 transfers
TGV 9583+
29542+
U229953:21 PM7h34Mannheim Hbf10:55 PMRome Leonardo da Vinci Fiumicino Airport$2011One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Mannheim to Rome
Travel to Rome easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mannheim to Rome.

This is compared to other travel options from Mannheim to Rome:
A bus is $408 (€343) less than a flight for this route with tickets for a flight from Mannheim to Rome costing on average $539 (€452).
Other travel options to Rome take longer:
Bus takes on average 19h 14m.
- Around 94 flights per day.
- Around 12 buses per day.
However, we recommend checking specific travel dates for your route between Mannheim and Rome as scheduled services by bus and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Rome Leonardo da Vinci Fiumicino Airport.
- Trains mostly depart from Mannheim Hbf and arrive in Rome Termini.
- Buses mostly depart from Mannheim, ZOB (Heinrich-Von-Stephan-Straße) and arrive in Roma, Autostazione Tiburtina.
- Travel with easyJet, Eurowings, Lufthansa, ITA, Malta Air, Vueling, Avion Express Malta, Swiss, Lufthansa Cityline, Icelandair, Brussels Airlines, Condor Flugdienst, Qatar Airways, Air Baltic, Croatia Airlines, Helvetic Airways, Lot Polish Airlines, British Airways, Ryanair, Edelweiss Air, Lufthansa City Airlines, Air France, KLM, Air Dolomiti, Austrian Airlines, AJet, GetJet Airlines, TAP Portugal to go to Rome by flight.
- Travel with FlixBus, BlaBlaCar Bus, Marino Autolinee to go to Rome by bus.
- 13 direct flights per day with easyJet, Eurowings, Lufthansa, ITA, Malta Air, Avion Express Malta, Condor Flugdienst, Ryanair.
- 1 direct buses per day with FlixBus.
Travelling from Mannheim to Rome: related information
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