Travel optionsfrom Prague to Mannheim
How to get from Prague to Mannheim by train, bus or flight.
Our recommendation
The best way to travel from Prague to Mannheim is by taking a train because it’s the best combination of price and speed.
RJ 174 · BUS 10174 · ICE 1552 · ICE 6772:41 PM8h48Prague-Holešovice11:29 PMMannheim Hbf€401One-way3 transfers
Cheapest
RJ 174 · BUS 10174 · ICE 1552 · ICE 6772:41 PM8h48Prague-Holešovice11:29 PMMannheim Hbf€401One-way3 transfers
Fastest
DE44068:50 AM1h00Prague Vaclav Havel Airport9:50 AMFrankfurt am Main Airport€1361One-way0 transfers
Other options
R 686 · BUS 10174 · ICE 1552 · ICE 6771:47 PM9h42Prague hlavní nádraží11:29 PMMannheim Hbf€401One-way3 transfers
EX 354 · 3576 · ICE 526 · ICE 7751:35 PM8h22Prague hlavní nádraží9:57 PMMannheim Hbf€491One-way3 transfers
EX 354 · 3576 · ICE 526 · ICE 7751:35 PM8h22Prague hlavní nádraží9:57 PMMannheim Hbf€491One-way3 transfers
FlixBus5:45 PM7h20Praha, Na Knížecí1:05 AMMannheim, ZOB (Heinrich-Von-Stephan-Straße)€411One-way0 transfers
FlixBus5:15 PM7h50Praha, ÚAN Florenc1:05 AMMannheim, ZOB (Heinrich-Von-Stephan-Straße)€411One-way0 transfers
FlixBus7:55 AM7h40Praha, Na Knížecí3:35 PMMannheim, ZOB (Heinrich-Von-Stephan-Straße)€571One-way0 transfers
LH14016:35 PM1h10Prague Vaclav Havel Airport7:45 PMFrankfurt am Main Airport€791One-way0 transfers
LH13939:05 AM1h10Prague Vaclav Havel Airport10:15 AMFrankfurt am Main Airport€961One-way0 transfers
LH13972:20 PM1h10Prague Vaclav Havel Airport3:30 PMFrankfurt am Main Airport€961One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Travel Information
Compare train, bus, and flight for Prague to Mannheim
Omio recommends booking the bus as it is the most popular option from Prague to Mannheim among Omio's users. If you are prioritising price take the bus with prices starting from €26. For those with little time consider booking a flight which can get you there in 1h 14m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €26, and a flight costs an average of €80.
Distance: 267 miles (431 km)
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
€40 Average price Cheapest | €92 Average price | €143 Average price | €92 Average price (fuel + tolls) |
7h 27m Average total duration 6h 57m Onboard + 30m Additional time* | 8h 25m Average total duration 7h 55m Onboard + 30m Additional time* | 4h 14m Average total duration Fastest 1h 14m Onboard + 3h 0m Additional time* | 5h 51m Average total duration (door-to-door) |
0.4 - 1.1kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.3 - 2.6kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Prague to Mannheim:
A bus is €52 less than a train for this route with tickets for a train from Prague to Mannheim costing on average €92.
A bus is €103 less than a flight for this route with tickets for a flight from Prague to Mannheim costing on average €143.
Other travel options to Mannheim take longer:
Bus takes on average 6h 57m.
Train takes on average 7h 55m.
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Prague to Mannheim
Travel to Mannheim easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Mannheim.

This is compared to other travel options from Prague to Mannheim:
A bus is €52 less than a train for this route with tickets for a train from Prague to Mannheim costing on average €92.
A bus is €103 less than a flight for this route with tickets for a flight from Prague to Mannheim costing on average €143.
Other travel options to Mannheim take longer:
Bus takes on average 6h 57m.
Train takes on average 7h 55m.
- Around 62 flights per day.
- Around 12 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between Prague and Mannheim as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Mannheim Hbf.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Mannheim, ZOB (Heinrich-Von-Stephan-Straße).
- Travel with FlixBus, BlaBlaCar, BlaBlaCar Bus to go to Mannheim by bus.
- Travel with Lufthansa to go to Mannheim by flight.
- Travel with Deutsche Bahn, České dráhy, ÖBB | Euro City (EC) to go to Mannheim by train.
- 6 direct buses per day with FlixBus, BlaBlaCar.
- 0 direct trains per day with ÖBB | Euro City (EC).
- 7 direct flights per day with Lufthansa.
Travelling from Prague to Mannheim: related information
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