Travel Information
Compare train, bus, and flight for Prague to Mannheim
Omio recommends booking the bus as it is the most popular option from Prague to Mannheim among Omio's users. If you are prioritising price take the bus with prices starting from $33. For those with little time consider booking a flight which can get you there in 1h 18m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $33, and a flight costs an average of $99.
Distance: 267 miles (431 km)
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
$56 Average price Cheapest | $101 Average price | $176 Average price |
7h 28m Average total duration 6h 58m Onboard + 30m Additional time* | 9h 8m Average total duration 8h 38m Onboard + 30m Additional time* | 4h 18m Average total duration Fastest 1h 18m Onboard + 3h 0m Additional time* |
0.4 - 1.1kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.3 - 2.6kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Prague to Mannheim
How to get from Prague to Mannheim by train, bus or flight.
Our recommendation
The best way to travel from Prague to Mannheim is by taking a bus because it’s the best combination of price and speed.
FlixBus7:55 AM7h40Praha, Na Knížecí3:35 PMMannheim, ZOB (Heinrich-Von-Stephan-Straße)$591One-way0 transfers
Cheapest
FlixBus5:45 PM7h20Praha, Na Knížecí1:05 AMMannheim, ZOB (Heinrich-Von-Stephan-Straße)$571One-way0 transfers
Fastest
DE44085:00 PM1h00Prague Vaclav Havel Airport6:00 PMFrankfurt am Main Airport$2541One-way0 transfers
Other options
EX 356 · ICE 109011:35 AM9h12Prague hlavní nádraží8:47 PMMannheim Hbf$1591One-way1 transfer
RJ 170 · IC 2044 · ICE 5938:47 PM13h43Prague hlavní nádraží10:30 AMMannheim Hbf$1421One-way2 transfers
EX 358 · ICE 9129:35 AM9h29Prague hlavní nádraží7:04 PMMannheim Hbf$1871One-way1 transfer
FlixBus7:35 AM8h00Praha, ÚAN Florenc3:35 PMMannheim, ZOB (Heinrich-Von-Stephan-Straße)$591One-way0 transfers
FlixBus5:15 PM7h50Praha, ÚAN Florenc1:05 AMMannheim, ZOB (Heinrich-Von-Stephan-Straße)$571One-way0 transfers
FlixBus8:40 PM6h20Praha, Na Knížecí3:00 AMMannheim, ZOB (Heinrich-Von-Stephan-Straße)$591One-way0 transfers
DE4408+
ICE 2055:00 PM5h26Prague Vaclav Havel Airport10:26 PMMannheim Hbf$2441One-way1 transfer
DE4408+
ICE 6155:00 PM4h25Prague Vaclav Havel Airport9:25 PMMannheim Hbf$2511One-way1 transfer
DE4408+
S9 · ICE 7755:00 PM4h57Prague Vaclav Havel Airport9:57 PMMannheim Hbf$2511One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 04
May 05
May 06
May 07
May 08
May 09
May 10
May 11
May 12
May 13
May 14
May 15
May 16
May 17
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Prague to Mannheim
Travel to Mannheim easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Mannheim.

This is compared to other travel options from Prague to Mannheim:
A bus is $2 (€1) less than a train for this route with tickets for a train from Prague to Mannheim costing on average $35 (€28).
A bus is $66 (€53) less than a flight for this route with tickets for a flight from Prague to Mannheim costing on average $99 (€79).
Other travel options to Mannheim take longer:
Bus takes on average 6h 20m.
Train takes on average 7h 49m.
- Around 58 flights per day.
- Around 12 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between Prague and Mannheim as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Mannheim Hbf.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Mannheim, ZOB (Heinrich-Von-Stephan-Straße).
- Travel with Deutsche Bahn, ÖBB | Euro City (EC) to go to Mannheim by train.
- Travel with Lufthansa to go to Mannheim by flight.
- Travel with FlixBus, BlaBlaCar, BlaBlaCar Bus to go to Mannheim by bus.
- 0 direct trains per day with ÖBB | Euro City (EC).
- 7 direct flights per day with Lufthansa.
- 6 direct buses per day with FlixBus, BlaBlaCar.
Travelling from Prague to Mannheim: related information
Here are some other resources that might have the information you need

