Travel Information
Compare train, bus, and flight for Prague to Mannheim
Omio recommends booking the train as it is the most popular option from Prague to Mannheim among Omio's users. If you are prioritising price take the bus with prices starting from €30. For those with little time consider booking a flight which can get you there in 1h 18m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €30, and a flight costs an average of €79.
Distance: 267 miles (431 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€87 Average price | €45 Average price Cheapest | €164 Average price |
9h 4m Average total duration 8h 34m Onboard + 30m Additional time* | 7h 36m Average total duration 7h 6m Onboard + 30m Additional time* | 4h 18m Average total duration Fastest 1h 18m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.1kg CO2 emissions | 1.3 - 2.6kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Prague to Mannheim
How to get from Prague to Mannheim by train, bus or flight.
Our recommendation
The best way to travel from Prague to Mannheim is by taking a bus because it’s the best combination of price and speed.
FlixBusCheapest
FlixBusFastest
DE4406Other options
EX 356 · ICE 512
EX 358 · ICE 514
rj 382 · IC 2442 · ICE 691
FlixBus
FlixBus
LO528 · LO379
LO522 · LO383
LO524 · LO379Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Prague to Mannheim
Travel to Mannheim easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Prague to Mannheim.

This is compared to other travel options from Prague to Mannheim:
A bus is $6 (€5) less than a train for this route with tickets for a train from Prague to Mannheim costing on average $44 (€35).
A bus is $62 (€49) less than a flight for this route with tickets for a flight from Prague to Mannheim costing on average $100 (€79).
Other travel options to Mannheim take longer:
Bus takes on average 6h 20m.
Train takes on average 7h 51m.
- Around 50 flights per day.
- Around 10 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between Prague and Mannheim as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Prague Vaclav Havel Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Prague hlavní nádraží and arrive in Mannheim Hbf.
- Buses mostly depart from Praha, ÚAN Florenc and arrive in Mannheim, ZOB (Heinrich-Von-Stephan-Straße).
- Travel with Deutsche Bahn, ÖBB | Euro City (EC) to go to Mannheim by train.
- Travel with FlixBus, BlaBlaCar, BlaBlaCar Bus to go to Mannheim by bus.
- Travel with Lufthansa to go to Mannheim by flight.
- 0 direct trains per day with ÖBB | Euro City (EC).
- 6 direct buses per day with FlixBus, BlaBlaCar.
- 5 direct flights per day with Lufthansa.
Travelling from Prague to Mannheim: related information
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