Travel Information
Compare train, bus, and flight for Mannheim to Lyon
Omio recommends booking the train as it is the most popular option from Mannheim to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €27. For those with little time consider booking a train which can get you there in 5h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €27, and a train costs an average of €53.
Distance: 309 miles (498 km)
Compare train with
Most popular Train | Bus |
|---|---|
€115 Average price | €44 Average price Cheapest |
5h 49m Average total duration Fastest 5h 19m Onboard + 30m Additional time* | 9h 43m Average total duration 9h 13m Onboard + 30m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.2kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Mannheim to Lyon
How to get from Mannheim to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Mannheim to Lyon is by taking a bus because it’s the best combination of price and speed.
51510Cheapest
51510Fastest
LH1074Other options
9580
9590+
12177
ICE 277+
87424+
5537
FlixBus · FlixBus
FlixBus
FlixBus · FlixBus
KL1826+
KL1431
ICE 1014+
AF7368+
AF1619
KL1814+
KL1431Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Mannheim to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mannheim to Lyon.

This is compared to other travel options from Mannheim to Lyon:
A bus is $33 (€26) less than a train for this route with tickets for a train from Mannheim to Lyon costing on average $67 (€53).
A bus is $108 (€86) less than a flight for this route with tickets for a flight from Mannheim to Lyon costing on average $143 (€114).
Other travel options to Lyon take longer:
Flight takes on average 3h 30m.
Bus takes on average 9h 0m.
- Around 17 flights per day.
- Around 8 buses per day.
- Around 3 trains per day.
However, we recommend checking specific travel dates for your route between Mannheim and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Mannheim Hbf and arrive in Lyon Part Dieu.
- Buses mostly depart from Mannheim, ZOB (Heinrich-Von-Stephan-Straße) and arrive in Lyon, Perrache Bus Station.
- Travel with BlaBlaCar Bus, FlixBus, BlaBlaCar, Union Ivkoni - Unibus to go to Lyon by bus.
- Travel with TGV, TGV INOUI, Deutsche Bahn to go to Lyon by train.
- 2 direct buses per day with BlaBlaCar Bus, FlixBus, BlaBlaCar.
- 1 direct trains per day with TGV, TGV INOUI, Deutsche Bahn.
Travelling from Mannheim to Lyon: related information
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