Travel Information
Compare train, bus, and flight for Mannheim to Lyon
Omio recommends booking the train as it is the most popular option from Mannheim to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from $33. For those with little time consider booking a train which can get you there in 5h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $33, and a train costs an average of $72.
Distance: 309 miles (498 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$154 Average price | $51 Average price Cheapest | $163 Average price (fuel + tolls) |
5h 49m Average total duration Fastest 5h 19m Onboard + 30m Additional time* | 9h 42m Average total duration 9h 12m Onboard + 30m Additional time* | 6h 33m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.2kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Mannheim to Lyon:
A bus is $103 (€85) less than a train for this route with tickets for a train from Mannheim to Lyon costing on average $154 (€126).
A bus is $254 (€208) less than a flight for this route with tickets for a flight from Mannheim to Lyon costing on average $304 (€249).
Other travel options to Lyon take longer:
Bus takes on average 9h 12m.
Flight takes on average 10h 19m.
Travel optionsfrom Mannheim to Lyon
How to get from Mannheim to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Mannheim to Lyon is by taking a bus because it’s the best combination of price and speed.
FlixBus11:59 PM10h31Mannheim, ZOB (Heinrich-Von-Stephan-Straße)10:30 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$391One-way0 transfers
Cheapest
FlixBus11:59 PM10h31Mannheim, ZOB (Heinrich-Von-Stephan-Straße)10:30 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$391One-way0 transfers
Fastest
LH10829:40 PM1h20Frankfurt am Main Airport11:00 PMLyon Saint Exupery Airport$3831One-way0 transfers
Other options
TGV 95802:42 PM5h16Mannheim Hbf7:58 PMLyon Part Dieu$981One-way0 transfers
ICE 277+
12177+
874249:37 AM8h22Mannheim Hbf5:59 PMLyon Part Dieu$1241One-way2 transfers
ICE 277+
5537+
874249:37 AM8h22Mannheim Hbf5:59 PMLyon Part Dieu$1241One-way2 transfers
FlixBus · FlixBus5:25 PM14h50Mannheim, ZOB (Heinrich-Von-Stephan-Straße)8:15 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$431One-way1 transfer
FlixBus9:20 AM11h30Mannheim, ZOB (Heinrich-Von-Stephan-Straße)8:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$441One-way0 transfers
FlixBus · FlixBus2:00 AM14h25Mannheim, ZOB (Heinrich-Von-Stephan-Straße)4:25 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)$491One-way1 transfer
ICE 1010+
AF7370+
AF121911:07 AM10h18Mannheim Hbf9:25 PMLyon Saint Exupery Airport$1901One-way2 transfers
ICE 204+
AF7370+
AF16197:33 AM13h52Mannheim Hbf9:25 PMLyon Saint Exupery Airport$1901One-way2 transfers
ICE 204+
AF7370+
AF12197:33 AM13h52Mannheim Hbf9:25 PMLyon Saint Exupery Airport$1901One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Mannheim to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mannheim to Lyon.

This is compared to other travel options from Mannheim to Lyon:
A bus is $103 (€85) less than a train for this route with tickets for a train from Mannheim to Lyon costing on average $154 (€126).
A bus is $254 (€208) less than a flight for this route with tickets for a flight from Mannheim to Lyon costing on average $304 (€249).
Other travel options to Lyon take longer:
Bus takes on average 9h 12m.
Flight takes on average 10h 19m.
- Around 21 flights per day.
- Around 8 buses per day.
- Around 3 trains per day.
However, we recommend checking specific travel dates for your route between Mannheim and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Mannheim Hbf and arrive in Lyon Part Dieu.
- Buses mostly depart from Mannheim, ZOB (Heinrich-Von-Stephan-Straße) and arrive in Lyon, Perrache Bus Station.
- Travel with TGV, SNCF | TGV INOUI, TER, Deutsche Bahn Intercity (DB IC) to go to Lyon by train.
- Travel with BlaBlaCar Bus, FlixBus, BlaBlaCar to go to Lyon by bus.
- 1 direct trains per day with TGV, SNCF | TGV INOUI.
- 2 direct buses per day with BlaBlaCar Bus, FlixBus, BlaBlaCar.
Travelling from Mannheim to Lyon: related information
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