4.9
4.6
Travel Information
Compare train, bus, and flight for Mannheim to Lyon
Omio recommends booking the train as it is the most popular option from Mannheim to Lyon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $65 For those with little time, consider booking a flight, which has an average total journey time of 4h 42m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $65, while a flight costs an average of $467.
Distance: 309 miles (498 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$75 Average price | $65 Average price Cheapest | $467 Average price | $161 Average price (fuel + tolls) |
5h 58m Average total duration 5h 28m Onboard + 30m Additional time* | 11h 35m Average total duration 11h 5m Onboard + 30m Additional time* | 4h 42m Average total duration Fastest 2h 42m Onboard + 2h 0m Additional time* | 6h 33m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.2kg CO2 emissions | 1.5 - 3.0kg CO2 emissions | - CO2 emissions |
 Most popular train company |  Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Mannheim to Lyon
Compare the available ways to get from Mannheim to Lyon, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Mannheim to Lyon:
A bus is $11 (€9) less than a train for this route with tickets for a train from Mannheim to Lyon costing on average $75 (€63).
A bus is $403 (€338) less than a flight for this route with tickets for a flight from Mannheim to Lyon costing on average $467 (€392).
Other travel options to Lyon take longer:
Train takes on average 5h 58m.
Bus takes on average 11h 35m.
The journey is about 1h 5m faster (5h 28m by train vs 6h 33m by car) and roughly $86 (€72) cheaper once you factor in fuel and tolls ($75 (€63) vs $161 (€135)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Travel optionsfrom Mannheim to Lyon
How to get from Mannheim to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Mannheim to Lyon is by taking a train because it’s the best combination of price and speed.
- 9580
2:42 PM 5h16 Mannheim Hbf 7:58 PM Lyon Part Dieu $101 1 One-way 0 transfers
Cheapest
- 9580
2:42 PM 5h16 Mannheim Hbf 7:58 PM Lyon Part Dieu $101 1 One-way 0 transfers
Fastest
- 9580
2:42 PM 5h16 Mannheim Hbf 7:58 PM Lyon Part Dieu $101 1 One-way 0 transfers
Other options
- 5537+
959011:40 AM 6h19 Mannheim Hbf 5:59 PM Lyon Part Dieu $115 1 One-way 1 transfer 
ICE 273 · ICE 9578+98776:37 AM 6h22 Mannheim Hbf 12:59 PM Lyon Part Dieu $121 1 One-way 2 transfers- 9877+9568
7:39 AM 5h20 Mannheim Hbf 12:59 PM Lyon Part Dieu $121 1 One-way 1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Mannheim to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mannheim to Lyon.
This is compared to other travel options from Mannheim to Lyon:
A bus is $11 (€9) less than a train for this route with tickets for a train from Mannheim to Lyon costing on average $75 (€63).
A bus is $403 (€338) less than a flight for this route with tickets for a flight from Mannheim to Lyon costing on average $467 (€392).
Other travel options to Lyon take longer:
Train takes on average 5h 58m.
Bus takes on average 11h 35m.
- Around 39 flights per day.
- Around 17 trains per day.
- Around 7 buses per day.
However, we recommend checking specific travel dates for your route between Mannheim and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Mannheim Hbf and arrive in Lyon Part Dieu.
- Buses mostly depart from Mannheim, ZOB (Heinrich-Von-Stephan-Straße) and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
- Travel with KLM, Lufthansa, Air France, Austrian Airlines, Air Baltic, Lot Polish Airlines, British Airways, Lufthansa Cityline, Air Dolomiti, KLM Cityhopper, Lufthansa City Airlines, Brussels Airlines, Twin Jet, CitizenPlane, BA Euroflyer to go to Lyon by flight.
- Travel with SNCF | TGV INOUI, TGV, TER, SNCF | Intercités de nuit, SNCF TER | Operated by SNCF Voyageurs 1187, SNCF | Intercités to go to Lyon by train.
- Travel with FlixBus, BlaBlaCar Bus to go to Lyon by bus.
- 4 direct flights per day with Lufthansa, Air Dolomiti, Twin Jet.
- 1 direct trains per day with SNCF | TGV INOUI, TGV.
- 2 direct buses per day with FlixBus, BlaBlaCar Bus.
Travelling from Mannheim to Lyon: related information
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