How to travel from Mannheim to Lyon

Sun, Sep 20
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Travel Information

Compare train, bus, and flight for Mannheim to Lyon

Omio recommends booking the flight as it is the most popular option from Mannheim to Lyon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $71 For those with little time, consider booking a flight, which has an average total journey time of 4h 42m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $71, while a flight costs an average of $491.

Distance: 309 miles (498 km)

Compare flight with

Most popular
Flight
Train
Bus
Driving

$491

Average price

$81

Average price

$71

Average price

Cheapest

$165

Average price

(fuel + tolls)

4h 42m

Average total duration

Fastest

2h 42m

Onboard

+

2h 0m

Additional time*

5h 57m

Average total duration

5h 27m

Onboard

+

30m

Additional time*

11h 31m

Average total duration

11h 1m

Onboard

+

30m

Additional time*

6h 33m

Average total duration

(door-to-door)

1.5 - 3.0kg

CO2 emissions

0.1 - 0.4kg

CO2 emissions

Lowest

0.5 - 1.2kg

CO2 emissions

-

CO2 emissions

Direct Options

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

The cheapest way to travel from Mannheim to Lyon is a bus with an average price of $71.

This is compared to other travel options from Mannheim to Lyon:

A bus is $10 less than a train for this route with tickets for a train from Mannheim to Lyon costing on average $81.

A bus is $420 less than a flight for this route with tickets for a flight from Mannheim to Lyon costing on average $491.

The fastest way to travel from Mannheim to Lyon is by flight with an average journey time of 4h 42m.

Other travel options to Lyon take longer:

Train takes on average 5h 57m.

Bus takes on average 11h 31m.

It's helpful to compare your options as there are 3 ways to travel between Mannheim and Lyon including taking a train, bus, and flight.
We recommend using the flight as it is the most popular way to get from Mannheim to Lyon among Omio's users.
Take the flight. It's the quicker way to make this trip, and the time saved usually justifies the slightly higher cost.

You'll arrive about 3h 51m sooner (2h 42m by flight vs 6h 33m by car). Tickets start at around $491 compared to roughly $165 in fuel and tolls — a bit more, but you get time back and avoid a long drive.

Driving makes more sense if you're travelling as a group, want flexibility on timing, or plan to stop en route.

Travel options
from Mannheim to Lyon

How to get from Mannheim to Lyon by train, bus or flight.

Our recommendation

bus

The best way to travel from Mannheim to Lyon is by taking a bus because it’s the best combination of price and speed.

  • FlixBusFlixBus · FlixBus
    2:00 AM10h40
    Mannheim, ZOB (Heinrich-Von-Stephan-Straße)
    12:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    $531One-way
    1 transfer

Cheapest

  • FlixBusFlixBus · FlixBus
    2:00 AM10h40
    Mannheim, ZOB (Heinrich-Von-Stephan-Straße)
    12:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    $531One-way
    1 transfer

Fastest

  • Air DolomitiEN8910
    8:20 AM1h20
    Frankfurt am Main Airport
    9:40 AMLyon Saint Exupery Airport
    $4661One-way
    0 transfers

Other options

  • TGVTGV 9580
    2:42 PM5h16
    Mannheim Hbf
    7:58 PMLyon Part Dieu
    $1581One-way
    0 transfers
  • Deutsche BahnICE 73+TGVTGV 9592+SNCF | TGV INOUI5539
    3:00 PM7h56
    Mannheim Hbf
    10:56 PMLyon Part Dieu
    $1591One-way
    2 transfers
  • Deutsche BahnICE 2533+SNCF | TGV INOUI5539+Südwestdeutsche Verkehrs-AG87448
    3:37 PM7h19
    Mannheim Hbf
    10:56 PMLyon Part Dieu
    $1801One-way
    2 transfers
  • FlixBusFlixBus · FlixBus
    5:25 PM14h50
    Mannheim, ZOB (Heinrich-Von-Stephan-Straße)
    8:15 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    $531One-way
    1 transfer
  • BlaBlaCar Bus51510
    8:05 PM9h05
    Mannheim, ZOB (Heinrich-Von-Stephan-Straße)
    5:10 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    $731One-way
    0 transfers
  • FlixBusFlixBus · FlixBus
    5:05 PM11h15
    Mannheim, ZOB (Heinrich-Von-Stephan-Straße)
    4:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)
    $881One-way
    1 transfer
  • KLMKL1832 · KL1427
    2:15 PM19h05
    Stuttgart Airport
    9:20 AMLyon Saint Exupery Airport
    $3241One-way
    1 transfer
  • KLMKL1830 · KL1427
    11:05 AM22h15
    Stuttgart Airport
    9:20 AMLyon Saint Exupery Airport
    $3251One-way
    1 transfer
  • KLMKL1832 · KL1435
    2:15 PM8h35
    Stuttgart Airport
    10:50 PMLyon Saint Exupery Airport
    $3261One-way
    1 transfer

Find all the dates and times for this journey by train, bus, flight, and ferry .

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FAQs: Travel from Mannheim to Lyon

Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mannheim to Lyon.

FAQs
There are 3 options to travel between Mannheim and Lyon including taking a train, bus, and flight.
The cheapest way to travel from Mannheim to Lyon is a bus with an average price of $71.

This is compared to other travel options from Mannheim to Lyon:

A bus is $10 less than a train for this route with tickets for a train from Mannheim to Lyon costing on average $81.

A bus is $420 less than a flight for this route with tickets for a flight from Mannheim to Lyon costing on average $491.

The fastest way to travel from Mannheim to Lyon is by flight with an average journey time of 4h 42m.

Other travel options to Lyon take longer:

Train takes on average 5h 57m.

Bus takes on average 11h 31m.

The distance from Mannheim to Lyon is approximately 309 miles (498 km).
The average frequency per day from Mannheim to Lyon is:
  • Around 37 flights per day.
  • Around 16 trains per day.
  • Around 7 buses per day.

However, we recommend checking specific travel dates for your route between Mannheim and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.

These are the most popular departure and arrival points from Mannheim to Lyon:
  • Flights mostly depart from Frankfurt am Main Airport and arrive in Lyon Saint Exupery Airport.
  • Trains mostly depart from Mannheim Hbf and arrive in Lyon Part Dieu.
  • Buses mostly depart from Mannheim, ZOB (Heinrich-Von-Stephan-Straße) and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
If finding a good deal is your main consideration for your trip from Mannheim to Lyon, then we'll help you find the best value travel companies for you:
  • Travel with FlixBus, BlaBlaCar Bus to go to Lyon by bus.
  • Travel with TGV, SNCF TER | Operated by SNCF Voyageurs 1187, SNCF | TGV INOUI, SNCF | Intercités de nuit, TER, SNCF | Intercités to go to Lyon by train.
  • Travel with BA Euroflyer, Lufthansa Cityline, KLM Cityhopper, Brussels Airlines, Lufthansa City Airlines, Air France, KLM, Air Dolomiti, Austrian Airlines, Lufthansa, Air Baltic, Twin Jet, Lot Polish Airlines, British Airways to go to Lyon by flight.
Yes, there are direct services available from Mannheim to Lyon with the following travel companies:
  • 2 direct buses per day with FlixBus, BlaBlaCar Bus.
  • 1 direct trains per day with TGV, SNCF | TGV INOUI.
  • 4 direct flights per day with Air Dolomiti, Lufthansa, Twin Jet.
Omio customers who travel from Mannheim to Lyon often also extend their vacation to go to Paris, Barcelona, Milan, Geneva, London. Omio can help you plan your trip by finding the best connections between Lyon and these popular destinations at a great price.
Most travelers need at least three days in Lyon to see the main sights at a comfortable pace. If you want day trips or a slower itinerary, consider adding extra time.
In Lyon, you can explore Les Halles de Lyon Paul Bocuse, an indoor market offering gourmet food, take a river cruise on the Rhône and Saône, and discover the secret passageways of the traboules in Vieux Lyon. Attend a performance at the Opéra de Lyon or visit the Institut Lumière for cinema history. Don't miss the Basilica of Notre-Dame de Fourvière for panoramic views, Vieux Lyon for its Renaissance architecture, Parc de la Tête d'Or with its zoo and botanical garden, the Musée des Confluences, or the bustling Place Bellecour.
For a fulfilling experience in Lyon, spending 2 to 3 days is ideal. This allows you to explore key attractions such as Vieux Lyon, Basilica of Notre-Dame de Fourvière, and the Musée des Confluences, while also enjoying the city's renowned gastronomy and vibrant cultural scene.
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