- Must visit
Musée des Beaux-Arts de Lyon
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Cheapest price on Oct 15
$42
Average ticket price on Oct 15
$66
Fastest journey on Oct 15
9 h 5 m
Average journey duration on Oct 15
11 h 25 m
Buses on Oct 15
7
Distance
498 km
The best way to find a cheap bus ticket from Mannheim to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mannheim to Lyon will cost around $66 if you buy it on the day, but the cheapest tickets can be found for only $42.
On Thu, Oct 15, we found 7 buses from Mannheim to Lyon, including 3 direct services.
On Thu, Oct 15 the direct buses cover the 498 km distance in an average of 11 h 25 m but if you time it right, some buses will get you there in just 9 h 5 m .
On Thu, Oct 15 the slowest buses will take 13 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
51510
FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
51510
FlixBus
FlixBus
FlixBus · FlixBus
FlixBus · FlixBusBuses from Mannheim to Lyon run on average 7 times per day, taking around 11h 1m. Cheap bus tickets for this journey start at $31 but you can travel from only $9 by train.
There are 2 buses per day. The earliest bus runs at 00:15, the last at 23:55. The fastest bus covers the 309 miles (498 km) distance in 8h 45m.
Distance 309 miles (498 km) |
Average bus duration 11h 1m |
Cheapest ticket price $31 |
Buses per day 7 |
Direct buses 2 |
Fastest bus 8h 45m |
First bus 12:15 AM |
Last bus 11:55 PM |
Cheapest Month Dec |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Oct - Dec |
Busiest Day Wed |
Least Busy Day Thu |
Best time to book 21 days |
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:00AM | Arrival Time 02:25PM | Duration 14h25 | Departure days Tue | Cheapest price $55 |
Operator FlixBus | Departure Time 12:10AM | Arrival Time 01:45PM | Duration 13h35 | Departure days Tue | Cheapest price $63 |
Operator BlaBlaCar Bus | Departure Time 12:15AM | Arrival Time 01:40PM | Duration 13h25 | Departure days Mon | Cheapest price $53 |
Operator FlixBus | Departure Time 01:10AM | Arrival Time 02:45PM | Duration 13h35 | Departure days Mon, Wed, Thu, Fri | Cheapest price $52 |
Operator FlixBus | Departure Time 02:00AM | Arrival Time 03:20PM | Duration 13h20 | Departure days Mon, Wed, Thu, Fri, Sun | Cheapest price $55 |
Operator FlixBus | Departure Time 03:05AM | Arrival Time 05:45PM | Duration 14h40 | Departure days Mon, Fri, Sun | Cheapest price $46 |
Operator FlixBus | Departure Time 05:50AM | Arrival Time 10:50PM | Duration 17h00 | Departure days Tue | Cheapest price $60 |
Operator FlixBus | Departure Time 07:20AM | Arrival Time 06:50PM | Duration 11h30 | Departure days Tue | Cheapest price $50 |
Operator FlixBus | Departure Time 09:20AM | Arrival Time 08:50PM | Duration 11h30 | Departure days Mon, Wed, Thu, Fri, Sun | Cheapest price $45 |
Operator BlaBlaCar Bus | Departure Time 12:30PM | Arrival Time 03:30AM | Duration 15h00 | Departure days Tue | Cheapest price $69 |
Operator BlaBlaCar Bus | Departure Time 01:30PM | Arrival Time 03:30AM | Duration 14h00 | Departure days Mon | Cheapest price $48 |
Operator FlixBus | Departure Time 01:40PM | Arrival Time 02:45AM | Duration 13h05 | Departure days Tue | Cheapest price $56 |
Operator FlixBus | Departure Time 02:40PM | Arrival Time 03:45AM | Duration 13h05 | Departure days Tue | Cheapest price $48 |
Operator FlixBus | Departure Time 03:05PM | Arrival Time 02:35AM | Duration 11h30 | Departure days Sat | Cheapest price $80 |
Operator FlixBus | Departure Time 03:25PM | Arrival Time 06:15AM | Duration 14h50 | Departure days Tue | Cheapest price $57 |
Operator FlixBus | Departure Time 04:05PM | Arrival Time 03:35AM | Duration 11h30 | Departure days Sat | Cheapest price $55 |
Operator FlixBus | Departure Time 04:25PM | Arrival Time 05:05AM | Duration 12h40 | Departure days Wed, Thu, Sat | Cheapest price $51 |
Operator FlixBus | Departure Time 05:05PM | Arrival Time 04:20AM | Duration 11h15 | Departure days Mon, Fri, Sun | Cheapest price $45 |
Operator FlixBus | Departure Time 05:25PM | Arrival Time 08:15AM | Duration 14h50 | Departure days Mon, Wed, Thu, Fri, Sun | Cheapest price $46 |
Operator BlaBlaCar | Departure Time 05:40PM | Arrival Time 11:50PM | Duration 6h10 | Departure days Thu | Cheapest price $59 |
Operator BlaBlaCar Bus | Departure Time 06:05PM | Arrival Time 03:10AM | Duration 9h05 | Departure days Sat | Cheapest price $39 |
Operator BlaBlaCar Bus | Departure Time 07:05PM | Arrival Time 04:10AM | Duration 9h05 | Departure days Sat | Cheapest price $39 |
Operator BlaBlaCar Bus | Departure Time 08:05PM | Arrival Time 05:10AM | Duration 9h05 | Departure days Thu, Fri, Sun | Cheapest price $42 |
Operator FlixBus | Departure Time 09:40PM | Arrival Time 01:25PM | Duration 15h45 | Departure days Wed | Cheapest price $51 |
Operator BlaBlaCar Bus | Departure Time 10:15PM | Arrival Time 11:40AM | Duration 13h25 | Departure days Mon | Cheapest price $76 |
Operator FlixBus | Departure Time 10:59PM | Arrival Time 09:30AM | Duration 10h31 | Departure days Sat | Cheapest price $59 |
Operator FlixBus | Departure Time 11:59PM | Arrival Time 10:30AM | Duration 10h31 | Departure days Mon, Thu, Fri, Sun | Cheapest price $43 |
The table below shows live departures for Mannheim to Lyon buses for today, Wednesday, October 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 5:25 PM Mannheim, ZOB (Heinrich-Von-Stephan-Straße) | 14h50 | 8:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 9:40 PM Mannheim, ZOB (Heinrich-Von-Stephan-Straße) | 15h45 | 1:25 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
| Thursday, October 15 | |||||
FlixBus · FlixBus | 1:10 AM Mannheim, ZOB (Heinrich-Von-Stephan-Straße) | 13h35 | 2:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 2:00 AM Mannheim, ZOB (Heinrich-Von-Stephan-Straße) | 13h20 | 3:20 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 9:20 AM Mannheim, ZOB (Heinrich-Von-Stephan-Straße) | 11h30 | 8:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 4:25 PM Mannheim, ZOB (Heinrich-Von-Stephan-Straße) | 12h40 | 5:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Discover the best of Lyon — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Lyon trip today.
Major fine arts museum in a former abbey, with strong collections from antiquity to modern art. A core cultural stop in Lyon.
Museum of cinema miniatures and film props in Vieux Lyon. Popular for detailed sets, special-effects history, and family-friendly exhibits.
Excellent free natural history and ethnography museum with fossils, animals, and global cultures. A strong local favorite, especially for families.
Renaissance quarter with cobbled lanes, traboules, courtyards, and major monuments. Essential for atmosphere, history, and walking exploration.
Central peninsula between the Rhône and Saône, packed with elegant streets, squares, shopping, and many of Lyon’s classic city views.
Historic silk-workers’ hill district with stairways, murals, markets, and hidden passageways. Great for local character and city panoramas.
Pike dumplings in a rich crayfish sauce. A Lyon classic from traditional bouchons, prized for its delicate fish texture and luxurious sauce.
Crisp salad of frisée, bacon lardons, croutons, and a poached egg. A staple Lyonnaise bistro dish that reflects the city's hearty cooking style.
Slow-cooked onions with vinegar, often served warm or chilled. This old Lyonnais side dish is traditional in bouchons and pairs well with charcuterie.
Refined dining by Paul Bocuse, known for polished French cuisine and iconic Lyon dishes in an elegant, historic dining room.
Well-known traditional bouchon in Vieux Lyon, praised for generous Lyonnais specialties and a lively old-city atmosphere.
Historic bouchon near Place Bellecour serving quenelles, salade lyonnaise, and classic regional fare in a warm traditional setting.
Moderate for Western Europe: hotels and dining are mid-priced, while public transport is good value for visitors.
Service is usually included. Round up or leave 5-10% for great restaurant service. Round up taxi fares; small change is fine in cafes.
Find answers to the most common questions about traveling from Mannheim to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

Most Mannheim to Lyon buses use the Mannheim, ZOB (Heinrich-Von-Stephan-Straße) to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) station pair, with some services arriving at Lyon, Gare Routière de Perrache. Use this guide to compare Mannheim and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Mannheim, ZOB (Heinrich-Von-Stephan-Straße) is 2 km from Mannheim city centre. Public transport options include:
Mannheim, ZOB (Heinrich-Von-Stephan-Straße) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food and coffee shop nearby.
Wi-Fi is available at Mannheim, ZOB (Heinrich-Von-Stephan-Straße). ATMs are located in nearby shopping area.
Ticket office support is available at Mannheim, ZOB (Heinrich-Von-Stephan-Straße).
Available at Mannheim, ZOB (Heinrich-Von-Stephan-Straße): Parking, Taxis, WC.
Accessibility facilities are available at Mannheim, ZOB (Heinrich-Von-Stephan-Straße): Ramp access for wheelchairs is provided.
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Free Wi-Fi. ATMs are located near the main entrance.
Ticket office support is available at Lyon, Gare Routière de Perrache.
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:
Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.
Ticket office support is available at Lyon, St Exupéry Aéroport.
Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.
Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.
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