Travel Information
Compare train, bus, and flight for Lyon to Mannheim
Omio recommends booking the train as it is the most popular option from Lyon to Mannheim among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $71 For those with little time, consider booking a flight, which has an average total journey time of 4h 42m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of $71, while a flight costs an average of $519.
Distance: 309 miles (498 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$136 Average price | $71 Average price Cheapest | $519 Average price | $162 Average price (fuel + tolls) |
5h 56m Average total duration 5h 26m Onboard + 30m Additional time* | 10h 43m Average total duration 10h 13m Onboard + 30m Additional time* | 4h 42m Average total duration Fastest 2h 42m Onboard + 2h 0m Additional time* | 6h 32m Average total duration (door-to-door) |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.2kg CO2 emissions | 1.5 - 3.0kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Lyon to Mannheim:
A bus is $54 (€46) less than a train for this route with tickets for a train from Lyon to Mannheim costing on average $121 (€101).
A bus is $422 (€353) less than a flight for this route with tickets for a flight from Lyon to Mannheim costing on average $488 (€408).
Other travel options to Mannheim take longer:
Train takes on average 6h 2m.
Bus takes on average 10h 50m.
The journey is about 1h 0m faster (5h 32m by train vs 6h 32m by car) and roughly $42 (€35) cheaper once you factor in fuel and tolls ($121 (€101) vs $162 (€135)). You'll also arrive in the city centre rather than hunting for parking, and you can work, read, or watch the landscape go by instead of concentrating on the road.
Driving is still worth considering if you want to stop along the way or need a car once you arrive.
Travel optionsfrom Lyon to Mannheim
How to get from Lyon to Mannheim by train, bus or flight.
Our recommendation
The best way to travel from Lyon to Mannheim is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus6:05 PM12h40Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)6:45 AMMannheim, ZOB (Heinrich-Von-Stephan-Straße)$481One-way1 transfer
Cheapest
FlixBus · FlixBus6:05 PM12h40Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)6:45 AMMannheim, ZOB (Heinrich-Von-Stephan-Straße)$481One-way1 transfer
Fastest
LH2247 · LH21469:30 AM2h55Lyon Saint Exupery Airport12:25 PMStuttgart Airport$4341One-way1 transfer
Other options
958310:01 AM5h17Lyon Part Dieu3:18 PMMannheim Hbf$1431One-way0 transfers
TGV 958310:01 AM5h17Lyon Part Dieu3:18 PMMannheim Hbf$1481One-way0 transfers
5516+
956311:38 AM6h39Lyon Part Dieu6:17 PMMannheim Hbf$1521One-way1 transfer
FlixBus11:00 PM10h15Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)9:15 AMMannheim, ZOB (Heinrich-Von-Stephan-Straße)$481One-way0 transfers
FlixBus · FlixBus5:05 PM11h40Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)4:45 AMMannheim, ZOB (Heinrich-Von-Stephan-Straße)$491One-way1 transfer
FlixBus7:30 AM11h30Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)7:00 PMMannheim, ZOB (Heinrich-Von-Stephan-Straße)$501One-way0 transfers
LH2251 · LH21525:50 PM4h55Lyon Saint Exupery Airport10:45 PMStuttgart Airport$2791One-way1 transfer
EN8911+
ICE 10910:45 AM5h41Lyon Saint Exupery Airport4:26 PMMannheim Hbf$3151One-way1 transfer
LH1079+
ICE 2056:55 PM3h31Lyon Saint Exupery Airport10:26 PMMannheim Hbf$3171One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Lyon to Mannheim
Travel to Mannheim easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Mannheim.

This is compared to other travel options from Lyon to Mannheim:
A bus is $65 (€55) less than a train for this route with tickets for a train from Lyon to Mannheim costing on average $136 (€113).
A bus is $449 (€375) less than a flight for this route with tickets for a flight from Lyon to Mannheim costing on average $519 (€434).
Other travel options to Mannheim take longer:
Train takes on average 5h 56m.
Bus takes on average 10h 43m.
- Around 40 flights per day.
- Around 10 trains per day.
- Around 7 buses per day.
However, we recommend checking specific travel dates for your route between Lyon and Mannheim as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Lyon Saint Exupery Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Lyon Part Dieu and arrive in Mannheim Hbf.
- Buses mostly depart from Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) and arrive in Mannheim, ZOB (Heinrich-Von-Stephan-Straße).
- Travel with BA Euroflyer, Lufthansa Cityline, KLM Cityhopper, Brussels Airlines, Lufthansa City Airlines, Air France, KLM, Air Dolomiti, Austrian Airlines, Lufthansa, Air Baltic, Twin Jet, Lot Polish Airlines, British Airways to go to Mannheim by flight.
- Travel with BlaBlaCar Bus, FlixBus to go to Mannheim by bus.
- Travel with TGV, SNCF | TGV INOUI, SNCF | Intercités de nuit to go to Mannheim by train.
- 4 direct flights per day with Air Dolomiti, Lufthansa, Twin Jet.
- 2 direct buses per day with BlaBlaCar Bus, FlixBus.
- 2 direct trains per day with TGV, SNCF | TGV INOUI.
Travelling from Lyon to Mannheim: related information
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