Travel Information
Compare train, bus, and flight for Lyon to Mannheim
Omio recommends booking the train as it is the most popular option from Lyon to Mannheim among Omio's users. If you are prioritising price take the bus with prices starting from $33. For those with little time consider booking a flight which can get you there in 1h 0m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of $33, and a flight costs an average of $124.
Distance: 309 miles (498 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$121 Average price | $53 Average price Cheapest | $272 Average price |
5h 44m Average total duration 5h 14m Onboard + 30m Additional time* | 9h 17m Average total duration 8h 47m Onboard + 30m Additional time* | 4h 0m Average total duration Fastest 1h 0m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.2kg CO2 emissions | 1.5 - 3.0kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Lyon to Mannheim
How to get from Lyon to Mannheim by train, bus or flight.
Our recommendation
The best way to travel from Lyon to Mannheim is by taking a bus because it’s the best combination of price and speed.
515113:20 AM9h20Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)12:40 PMMannheim, ZOB (Heinrich-Von-Stephan-Straße)$371One-way0 transfers
Cheapest
515113:20 AM9h20Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)12:40 PMMannheim, ZOB (Heinrich-Von-Stephan-Straße)$371One-way0 transfers
Fastest
EN891110:30 AM1h20Lyon Saint Exupery Airport11:50 AMFrankfurt am Main Airport$8561One-way0 transfers
Other options
12176+
956311:38 AM6h39Lyon Part Dieu6:17 PMMannheim Hbf$1451One-way1 transfer
TGV 958310:01 AM5h17Lyon Part Dieu3:18 PMMannheim Hbf$1721One-way0 transfers
958310:01 AM5h17Lyon Part Dieu3:18 PMMannheim Hbf$1851One-way0 transfers
FlixBus7:30 AM11h30Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)7:00 PMMannheim, ZOB (Heinrich-Von-Stephan-Straße)$551One-way0 transfers
FlixBus11:00 PM10h15Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)9:15 AMMannheim, ZOB (Heinrich-Von-Stephan-Straße)$571One-way0 transfers
FlixBus · FlixBus12:20 AM11h00Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)11:20 AMMannheim, ZOB (Heinrich-Von-Stephan-Straße)$621One-way1 transfer
KL1428+
KL1819+
ICE 1099:55 AM6h31Lyon Saint Exupery Airport4:26 PMMannheim Hbf$3311One-way2 transfers
KL1428+
KL1819+
ICE 10119:55 AM6h58Lyon Saint Exupery Airport4:53 PMMannheim Hbf$3351One-way2 transfers
KL1428+
KL1819+
ICE 6119:55 AM7h30Lyon Saint Exupery Airport5:25 PMMannheim Hbf$3341One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Lyon to Mannheim
Travel to Mannheim easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Lyon to Mannheim.

This is compared to other travel options from Lyon to Mannheim:
A bus is $30 (€24) less than a train for this route with tickets for a train from Lyon to Mannheim costing on average $63 (€50).
A bus is $90 (€72) less than a flight for this route with tickets for a flight from Lyon to Mannheim costing on average $124 (€99).
Other travel options to Mannheim take longer:
Train takes on average 5h 14m.
Bus takes on average 9h 15m.
- Around 20 flights per day.
- Around 8 buses per day.
- Around 6 trains per day.
However, we recommend checking specific travel dates for your route between Lyon and Mannheim as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Lyon Saint Exupery Airport and arrive in Frankfurt am Main Airport.
- Trains mostly depart from Lyon Part Dieu and arrive in Mannheim Hbf.
- Buses mostly depart from Lyon, Perrache Bus Station and arrive in Mannheim, ZOB (Heinrich-Von-Stephan-Straße).
- Travel with Volotea to go to Mannheim by flight.
- Travel with TGV, SNCF | TGV INOUI to go to Mannheim by train.
- Travel with BlaBlaCar Bus, FlixBus, BlaBlaCar to go to Mannheim by bus.
- 5 direct flights per day with Volotea.
- 2 direct trains per day with TGV, SNCF | TGV INOUI.
- 3 direct buses per day with BlaBlaCar Bus, FlixBus, BlaBlaCar.
Travelling from Lyon to Mannheim: related information
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