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4.6
Travel Information
Compare bus, train, and flight for Mainz to Brussels
Omio recommends booking the train as it is the most popular option from Mainz to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $50 For those with little time, consider booking a train, which has an average total journey time of 4h 12m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $50, while a flight costs an average of $545.
Distance: 183 miles (295 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$111 Average price | $50 Average price Cheapest | $545 Average price | $72 Average price (fuel + tolls) |
4h 12m Average total duration Fastest 3h 42m Onboard + 30m Additional time* | 8h 45m Average total duration 8h 15m Onboard + 30m Additional time* | 4h 32m Average total duration 2h 32m Onboard + 2h 0m Additional time* | 4h 23m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.7kg CO2 emissions | 0.9 - 1.8kg CO2 emissions | - CO2 emissions |
 Most popular train company |  Most popular bus company |  Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Mainz to Brussels
Compare the available ways to get from Mainz to Brussels, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Mainz to Brussels:
A bus is $62 less than a train for this route with tickets for a train from Mainz to Brussels costing on average $111.
A bus is $496 less than a flight for this route with tickets for a flight from Mainz to Brussels costing on average $545.
Other travel options to Brussels take longer:
Flight takes on average 4h 32m.
Bus takes on average 8h 45m.
You'll arrive about 41m sooner (3h 42m by train vs 4h 23m by car). Tickets start at around $111 compared to roughly $72 in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
Travel optionsfrom Mainz to Brussels
How to get from Mainz to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Mainz to Brussels is by taking a bus because it’s the best combination of price and speed.
9:30 AM7h45Mainz5:15 PMBrussels$391One-way0 transfers
Cheapest
- 9:30 AM7h45Mainz5:15 PMBrussels$391One-way0 transfers
Fastest
- 10:20 AM5h45Mainz4:05 PMBrussels$411One-way0 transfers
Other options
- 11:25 AM13h48Mainz1:13 AMBrussels$491One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Mainz to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mainz to Brussels.
This is compared to other travel options from Mainz to Brussels:
A bus is $62 less than a train for this route with tickets for a train from Mainz to Brussels costing on average $111.
A bus is $496 less than a flight for this route with tickets for a flight from Mainz to Brussels costing on average $545.
Other travel options to Brussels take longer:
Flight takes on average 4h 32m.
Bus takes on average 8h 45m.
- Around 25 flights per day.
- Around 7 trains per day.
- Around 3 buses per day.
However, we recommend checking specific travel dates for your route between Mainz and Brussels as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Brussels Airport.
- Trains mostly depart from Mainz Hbf and arrive in Brussels-Midi.
- Buses mostly depart from Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36) and arrive in Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord).
- Travel with Brussels Airlines, Lufthansa, KLM Cityhopper, CitizenPlane, Swiss, BA Cityflyer, KLM, Qatar Airways, Austrian Airlines, Air Baltic, Lot Polish Airlines, British Airways to go to Brussels by flight.
- Travel with FlixBus, BlaBlaCar Bus to go to Brussels by bus.
- Travel with Deutsche Bahn, Eurostar to go to Brussels by train.
- 6 direct flights per day with Brussels Airlines, Lufthansa, CitizenPlane, Air Baltic.
- 1 direct buses per day with FlixBus.
Travelling from Mainz to Brussels: related information
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