Travel Information
Compare bus, train, and flight for Mainz to Brussels
Omio recommends booking the train as it is the most popular option from Mainz to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from $20. For those with little time consider booking a flight which can get you there in 1h 0m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of $20, and a flight costs an average of $154.
Distance: 183 miles (295 km)
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
$98 Average price | $34 Average price Cheapest | $303 Average price |
4h 12m Average total duration 3h 42m Onboard + 30m Additional time* | 6h 0m Average total duration 5h 30m Onboard + 30m Additional time* | 4h 0m Average total duration Fastest 1h 0m Onboard + 3h 0m Additional time* |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.7kg CO2 emissions | 0.9 - 1.8kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Mainz to Brussels
How to get from Mainz to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Mainz to Brussels is by taking a bus because it’s the best combination of price and speed.
FlixBusCheapest
FlixBusFastest
LH1006Other options
ICE 1049 · ICE 16
IC 1947 · ICE 314
4470 · ICE 16
FlixBus · FlixBus
30481 · 1657
30483 · 50100
LH5654+
SN2812
EN8958+
SN2812
SN2614Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 12
Mar 13
Mar 14
Mar 15
Mar 16
Mar 17
Mar 18
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Mainz to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mainz to Brussels.

This is compared to other travel options from Mainz to Brussels:
A bus is $29 (€23) less than a train for this route with tickets for a train from Mainz to Brussels costing on average $49 (€40).
A bus is $134 (€108) less than a flight for this route with tickets for a flight from Mainz to Brussels costing on average $154 (€124).
Other travel options to Brussels take longer:
Train takes on average 3h 33m.
Bus takes on average 5h 45m.
- Around 27 flights per day.
- Around 5 trains per day.
- Around 3 buses per day.
However, we recommend checking specific travel dates for your route between Mainz and Brussels as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Brussels Airport.
- Trains mostly depart from Mainz Hbf and arrive in Brussels-Midi.
- Buses mostly depart from Mainz, Binger Schlag (Kurzzeitparkplatz) and arrive in Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord).
- Travel with FlixBus, BlaBlaCar, BlaBlaCar Bus to go to Brussels by bus.
- Travel with Lufthansa, Brussels Airlines to go to Brussels by flight.
- Travel with Deutsche Bahn, Österreichische Bundesbahnen, Süwex to go to Brussels by train.
- 2 direct buses per day with FlixBus, BlaBlaCar.
- 0 direct trains per day with Österreichische Bundesbahnen.
Travelling from Mainz to Brussels: related information
Here are some other resources that might have the information you need
