Travel Information
Compare train, bus, and flight for Mainz to Amsterdam
Omio recommends booking the train as it is the most popular option from Mainz to Amsterdam among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $61 For those with little time, consider booking a train, which has an average total journey time of 5h 15m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.3kg. Average ticket prices depend on the travel mode: a bus costs an average of $61, while a flight costs an average of $554.
Distance: 221 miles (356 km)
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$113 Average price | $61 Average price Cheapest | $554 Average price | $96 Average price (fuel + tolls) |
5h 15m Average total duration Fastest 4h 45m Onboard + 30m Additional time* | 10h 15m Average total duration 9h 45m Onboard + 30m Additional time* | 5h 23m Average total duration 3h 23m Onboard + 2h 0m Additional time* | 5h 8m Average total duration (door-to-door) |
0.1 - 0.3kg CO2 emissions Lowest | 0.4 - 0.9kg CO2 emissions | 1.1 - 2.1kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Mainz to Amsterdam:
A bus is $52 (€44) less than a train for this route with tickets for a train from Mainz to Amsterdam costing on average $113 (€95).
A bus is $494 (€415) less than a flight for this route with tickets for a flight from Mainz to Amsterdam costing on average $554 (€465).
Other travel options to Amsterdam take longer:
Flight takes on average 5h 23m.
Bus takes on average 10h 15m.
You'll arrive about 23m sooner (4h 45m by train vs 5h 8m by car). Tickets start at around $113 (€95) compared to roughly $96 (€81) in fuel and tolls — so you're paying a bit more, but getting hours of your day back, a city-centre arrival, and the freedom to work or relax instead of drive.
Driving makes more sense if you're travelling as a group (where fuel costs split several ways), want to stop along the way, or need a car once you arrive.
Travel optionsfrom Mainz to Amsterdam
How to get from Mainz to Amsterdam by train, bus or flight.
Our recommendation
The best way to travel from Mainz to Amsterdam is by taking a bus because it’s the best combination of price and speed.
(Prague -> Amsterdam)5:55 AM7h35Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)1:30 PMAmsterdam, Piarcoplein (Amsterdam Sloterdijk)$281One-way0 transfers
Cheapest
(Prague -> Amsterdam)5:55 AM7h35Frankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)1:30 PMAmsterdam, Piarcoplein (Amsterdam Sloterdijk)$281One-way0 transfers
Fastest
KL18147:00 AM1h05Frankfurt am Main Airport8:05 AMAmsterdam Airport Schiphol$1,0291One-way0 transfers
Other options
IC 2241 · 10608 · 20070 · IC 35407:17 AM5h47Mainz Hbf1:04 PMAmsterdam Zuid$411One-way3 transfers
IC 1947 · 10616 · 20078 · IC 355611:20 AM5h44Mainz Hbf5:04 PMAmsterdam Zuid$421One-way3 transfers
IC 2241 · 26808 · 18926 · IC 39407:17 AM5h58Mainz Hbf1:15 PMAmsterdam Centraal$451One-way3 transfers
FlixBus · FlixBus8:20 AM11h55Mainz, Binger Schlag (Kurzzeitparkplatz)8:15 PMAmsterdam, Piarcoplein (Amsterdam Sloterdijk)$491One-way1 transfer
FlixBus · FlixBus12:05 PM11h15Mainz, Binger Schlag (Kurzzeitparkplatz)11:20 PMAmsterdam, Piarcoplein (Amsterdam Sloterdijk)$561One-way1 transfer
FlixBus · FlixBus10:40 PM16h05Mainz, Binger Schlag (Kurzzeitparkplatz)2:45 PMAmsterdam, Piarcoplein (Amsterdam Sloterdijk)$1131One-way1 transfer
KL181811:45 AM1h15Frankfurt am Main Airport1:00 PMAmsterdam Airport Schiphol$2621One-way0 transfers
KL181610:15 AM1h15Frankfurt am Main Airport11:30 AMAmsterdam Airport Schiphol$2621One-way0 transfers
KL18202:15 PM1h15Frankfurt am Main Airport3:30 PMAmsterdam Airport Schiphol$2621One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Mainz to Amsterdam
Travel to Amsterdam easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Mainz to Amsterdam.

This is compared to other travel options from Mainz to Amsterdam:
A bus is $52 (€44) less than a train for this route with tickets for a train from Mainz to Amsterdam costing on average $113 (€95).
A bus is $494 (€415) less than a flight for this route with tickets for a flight from Mainz to Amsterdam costing on average $554 (€465).
Other travel options to Amsterdam take longer:
Flight takes on average 5h 23m.
Bus takes on average 10h 15m.
- Around 39 flights per day.
- Around 7 trains per day.
- Around 6 buses per day.
However, we recommend checking specific travel dates for your route between Mainz and Amsterdam as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Amsterdam Airport Schiphol.
- Trains mostly depart from Mainz Hbf and arrive in Amsterdam Centraal.
- Buses mostly depart from Mainz, Binger Schlag (Kurzzeitparkplatz) and arrive in Amsterdam, Piarcoplein (Amsterdam Sloterdijk).
- Travel with Lufthansa, KLM Cityhopper, Lufthansa Cityline, Swiss, BA Cityflyer, Lufthansa City Airlines, KLM, Air France, Air Dolomiti, Qatar Airways, Austrian Airlines, Air Baltic, Helvetic Airways, Lot Polish Airlines, British Airways, Cityjet to go to Amsterdam by flight.
- Travel with FlixBus to go to Amsterdam by bus.
- Travel with Deutsche Bahn, VIAS Rail GmbH to go to Amsterdam by train.
- 9 direct flights per day with Lufthansa, KLM Cityhopper, KLM, Air Dolomiti, Cityjet.
Travelling from Mainz to Amsterdam: related information
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