- Must visit
Uffizi Gallery
World-famous gallery with Botticelli, Leonardo, and Michelangelo. Essential for understanding Renaissance painting and one of Florence’s top visits.
Cheapest price on Sep 19
$142
Average ticket price on Sep 19
$142
Fastest journey on Sep 19
4 h 15 m
Average journey duration on Sep 19
4 h 24 m
Trains on Sep 19
20
Distance
435 km
The best way to find a cheap train ticket from Sant'Agnello to Florence is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Sant'Agnello to Florence will cost around $142 if you buy it on the day, but the cheapest tickets can be found for only $142.
It's difficult to get from Sant'Agnello to Florence without transferring at least once.










Omio recommends booking the train as it is the most popular option from Sant'Agnello to Florence among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $45 For those with little time, consider booking a flight, which has an average total journey time of 4h 12m. Average ticket prices depend on the travel mode: a bus costs an average of $45, while a flight costs an average of $459.
Distance: 270 miles (435 km)
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
$45 Average price Cheapest | $459 Average price | $103 Average price (fuel + tolls) | |
8h 5m Average total duration 7h 35m Onboard + 30m Additional time* | 4h 12m Average total duration Fastest 2h 12m Onboard + 2h 0m Additional time* | 5h 11m Average total duration (door-to-door) | |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Sant'Agnello to Florence:
A bus is $414 (€339) less than a flight for this route with tickets for a flight from Sant'Agnello to Florence costing on average $459 (€375).
Other travel options to Florence take longer:
Bus takes on average 7h 35m.
The table below shows live departures for Sant'Agnello to Florence trains for tomorrow, Saturday, September 19. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:32 AM S. Agnello | 4h39 | 10:11 AM Florence | 1 transfer | |
![]() | 5:52 AM S. Agnello | 4h35 | 10:27 AM Florence | 1 transfer | |
![]() | 6:28 AM S. Agnello | 4h43 | 11:11 AM Florence | 1 transfer | |
![]() | 7:04 AM S. Agnello | 4h42 | 11:46 AM Florence | 1 transfer | |
![]() | 8:53 AM S. Agnello | 4h53 | 1:46 PM Florence | 1 transfer |
Find all the dates and times for this journey
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a train from Sant'Agnello to Florence and enjoy the approximately 270 miles (435 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 03:45, the last at 22:22.
Distance 270 miles (435 km) |
First train 3:45 AM |
Last train 10:22 PM |
Cheapest Month Aug |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 5 days |
Discover the best of Florence — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence trip today.
World-famous gallery with Botticelli, Leonardo, and Michelangelo. Essential for understanding Renaissance painting and one of Florence’s top visits.
Houses Michelangelo’s David alongside major Renaissance sculptures. A must for first-time visitors interested in Florence’s artistic legacy.
Monastic museum with Fra Angelico frescoes and tranquil cells. Ideal for experiencing spiritual art in one of Florence’s most atmospheric spaces.
Florence’s monumental main square, framed by civic buildings and sculpture. A must for first impressions, history, and lively urban atmosphere.
The cathedral square is Florence’s ceremonial heart, surrounded by the Duomo, Baptistery, and bell tower. Essential for architecture lovers.
Riverside viewpoint with one of Florence’s classic panoramas. Best at sunset for sweeping views over the Arno, domes, and historic center.
Thick Florentine T-bone steak from Chianina beef, grilled rare over coals. It is the city's signature celebratory dish and a classic of Tuscan cuisine.
A rustic Tuscan bread soup with black cabbage, cannellini beans, vegetables, and olive oil. A beloved frugal dish rooted in Florentine home cooking.
A thick soup of bread, tomatoes, basil, garlic, and olive oil, served warm or at room temperature. It celebrates simple Tuscan ingredients and stale bread.
Three-Michelin-star fine dining by Enoteca Pinchiorri, known for refined Italian cuisine and an exceptional wine cellar. Elegant and formal.
Legendary casual stop for Lampredotto sandwiches and other tripe specialties. Simple, authentic street food experience in central Florence.
Historic steakhouse famed for Bistecca Alla Fiorentina and classic Tuscan dishes. Traditional, bustling atmosphere near Santa Croce.
Moderate for Italy: hotels in the center are pricier, but dining and transit are reasonable versus Rome or Venice.
Service is often included. Round up or leave €1-2 at cafés, 5-10% for great restaurant service, and round up taxi fares.
Official public transport app
Firenze Santa Maria Novella -> Piazza del Duomo, Florence
Find answers to the most common questions about traveling from Sant'Agnello to Florence by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, this guide helps you travel smarter and with confidence.

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