- Must visit
Paolo Orsi Regional Archaeological Museum
Leading archaeology museum with superb Greek and Roman finds, essential for understanding ancient Syracuse and eastern Sicily.
The best way to find a cheap train ticket from Pisa to Syracuse is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Syracuse will cost around $117 if you buy it on the day, but the cheapest tickets can be found for only $100.
On Wed, Nov 04, we found 2 trains from Pisa to Syracuse, including 2 direct services.
On Wed, Nov 04 the direct trains cover the 845 km distance in an average of 17 h 6 m but if you time it right, some trains will get you there in just 16 h 10 m .
On Wed, Nov 04 the slowest trains will take 18 h 2 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

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Trains from Pisa to Syracuse run on average 30 times per day, taking around 15h 36m. Cheap train tickets for this journey start at $12 if you book in advance.
The earliest train runs at 02:21, the last at 21:53. The fastest train covers the 525 miles (845 km) distance in 12h 37m.
Distance 525 miles (845 km) |
Average train duration 15h 36m |
Cheapest ticket price $12 |
Trains per day 30 |
Fastest train 12h 37m |
First train 2:21 AM |
Last train 9:53 PM |
Cheapest Month Oct |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Apr - Jun |
Best time to book 1 day |
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Pisa to Syracuse.
The table below shows live departures for Pisa to Syracuse trains for tomorrow, Wednesday, November 4. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:21 AM Pisa | 16h10 | 4:31 PM Syracuse | 0 transfersDirect | |
![]() | 1:21 AM Pisa | 18h02 | 7:23 PM Syracuse | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
Discover the best of Syracuse — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse trip today.
Leading archaeology museum with superb Greek and Roman finds, essential for understanding ancient Syracuse and eastern Sicily.
Gallery inside Palazzo Bellomo showing medieval and Baroque art, including Antonello da Messina's celebrated Annunciation.
Interactive science museum focused on Archimedes and Leonardo, engaging for families and visitors curious about inventions.
Syracuse's historic island center, packed with Baroque lanes, seafront walks, ancient ruins, and a vibrant local atmosphere.
Grand limestone square framed by the cathedral and palaces, one of Sicily's most elegant and memorable urban spaces.
Freshwater spring beside the sea linked to myth, famous for papyrus plants and its central place in Ortigia legends.
Pasta with fresh tomato sauce, fried eggplant, ricotta salata and basil. A classic Sicilian dish tied to nearby Catania and widely loved in Syracuse.
Rice balls stuffed with ragù, cheese or butter, then breaded and fried. A staple Sicilian street food eaten across Syracuse.
Small fried fish, often anchovies or whitebait, served simply with lemon. It reflects Syracuse's strong seafood tradition and daily catch.
Refined Michelin-starred dining on Ortigia with creative Sicilian tasting menus, elegant service and a romantic historic setting.
Historic market stop famous for sandwiches, charcuterie, cheese and quick Sicilian bites amid the bustling Ortigia food market.
Well-known Ortigia seafood restaurant serving local fish, pasta and Sicilian classics in a polished but relaxed atmosphere.
Moderate for Sicily. Dining and hotels are often cheaper than Rome or Milan, while summer stays in Ortigia and tourist dining can raise costs. Local buses are low cost.
Service is often included or minimal. Round up or leave 5-10% at restaurants for good service. Taxis are usually rounded up. In cafes, small change is enough.
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Syracuse.
Find answers to the most common questions about traveling from Pisa to Syracuse by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Syracuse, this guide helps you travel smarter and with confidence.

Most Pisa to Syracuse trains use the Pisa Centrale to station pair. Use this guide to compare Pisa and Syracuse train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Pisa Centrale has practical services for this route, including Wifi, Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Ticket Office, Bike Parking, Bike Rental, and Information Desk.
Food options include: McDonald's, Panetteria Binario 1
There is free Wi-Fi available at the McDonald's.
The ticket office is open Mon - Sun: 06:00 - 20:30. Information desks are located just outside the station on Piazza Vittorio Emanuele II.
Luggage storage is there is a luggage storage office near the end of Platform 1.
Available at Pisa Centrale: Parking, Taxis, WC.
Available at Pisa Centrale: Bike Parking, Bike Rental.
Accessibility facilities are available at Pisa Centrale: Accessible facilities including barrier-free restrooms, elevators, ramps, and disabled parking. Sala Blu mobility assistance available from 07:45 to 22:30 with advanced one-hour notice.
Nearby hotels include Hotel NH Pisa, Hotel La Pace, Hotel Maria.
Here are some other resources that might have the information you need