- Must visit
Paolo Orsi Regional Archaeological Museum
Sicily’s most important archaeological museum, with major collections from prehistoric to Greek and Roman Syracuse. A key stop for understanding the city’s ancient history.
Cheapest price
$129
Average price
$133
Fastest journey
15 h 57 m
Average duration
17 h
Trains per day
2
Distance
845 km
The best way to find a cheap train ticket from Pisa to Syracuse is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Syracuse will cost around $133 if you buy it on the day, but the cheapest tickets can be found for only $129.
Of the 2 trains that leave Pisa for Syracuse on Mon, Jun 22, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Jun 22 the direct trains cover the 845 km distance in an average of 17 h but if you time it right, some trains will get you there in just 15 h 57 m .
On Mon, Jun 22 the slowest trains will take 18 h 2 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the train as it is the most popular option from Pisa to Syracuse among Omio's users. If you are prioritising price take the flight with prices starting from $39. For those with little time consider booking a flight which can get you there in 1h 33m. The ticket price range depends on the travel mode: a flight costs an average of $39, and a train costs an average of $46.
Distance: 525 miles (845 km)
Most popular Train | Flight | Bus |
|---|---|---|
$122 Average price | $39 Average price Cheapest | $110 Average price |
15h 41m Average total duration 15h 11m Onboard + 30m Additional time* | 4h 33m Average total duration Fastest 1h 33m Onboard + 3h 0m Additional time* | 24h 12m Average total duration 23h 42m Onboard + 30m Additional time* |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Pisa to Syracuse:
A flight is $71 (€58) less than a bus for this route with tickets for a bus from Pisa to Syracuse costing on average $110 (€90).
A flight is $83 (€68) less than a train for this route with tickets for a train from Pisa to Syracuse costing on average $122 (€100).
Other travel options to Syracuse take longer:
Train takes on average 15h 11m.
Bus takes on average 23h 42m.
The table below shows live departures for Pisa to Syracuse trains for today, Sunday, June 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Intercity 511+ InterCityNotte 1955 | 2:53 PM Pisa Centrale | 18h14 | 9:07 AM Syracuse station | 1 transfer | |
Regionale Veloce 4050+ FRECCIAROSSA 9431+ InterCityNotte 1955 | 5:32 PM Pisa Centrale | 15h35 | 9:07 AM Syracuse station | 2 transfers | |
FRECCIAROSSA 8623+ InterCityNotte 1959 | 7:11 PM Pisa Centrale | 16h24 | 11:35 AM Syracuse station | 1 transfer | |
Regionale Veloce 4058+ FRECCIAROSSA 9435+ InterCityNotte 1959 | 7:32 PM Pisa Centrale | 16h03 | 11:35 AM Syracuse station | 2 transfers | |
| Monday, June 22 | |||||
![]() | 1:21 AM Pisa | 18h02 | 7:23 PM Syracuse | 0 transfersDirect | |
![]() | 1:34 AM Pisa | 15h57 | 5:31 PM Syracuse | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Pisa to Syracuse run on average 6 times per day, taking around 15h 11m. Cheap train tickets for this journey start at $46 (€38) but you can travel from only $39 (€32) by flight.
The earliest train runs at 02:21, the last at 21:53. The fastest train covers the 525 miles (845 km) distance in 15h 5m.
Distance 525 miles (845 km) |
Average train duration 15h 11m |
Cheapest ticket price $46 (€38) |
Trains per day 6 |
Fastest train 15h 5m |
First train 2:21 AM |
Last train 9:53 PM |
Cheapest Month Oct |
Cheapest Day Thu |
High Season Oct - Dec |
Low Season Apr - Jun |
Best time to book 1 day |
Discover the best of Syracuse — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse trip today.
Sicily’s most important archaeological museum, with major collections from prehistoric to Greek and Roman Syracuse. A key stop for understanding the city’s ancient history.
An art museum in a historic palace on Ortigia, known for Sicilian medieval and Renaissance works, including Antonello da Messina’s Annunciation.
An interactive museum with models and reconstructions of inventions linked to Leonardo and Archimedes. Popular with families and visitors exploring Ortigia.
The historic heart of Syracuse, packed with sea views, Baroque lanes, markets, and major landmarks. The top area for walking, photography, and atmosphere.
Syracuse’s most celebrated square, framed by elegant Baroque buildings and the cathedral. A classic must-see and especially beautiful in the evening.
A freshwater spring beside the sea, linked to Greek myth and lined with papyrus plants. One of Ortigia’s most photographed corners.
A local pasta preparation often made with tomatoes, garlic, olive oil, breadcrumbs, and sometimes anchovies, reflecting the simple coastal flavors of Syracuse.
Traditional Sicilian pasta with sardines, wild fennel, pine nuts, and raisins; a classic sweet-savory dish widely associated with eastern Sicily.
Swordfish cooked in a rich sauce with tomatoes, capers, olives, and onions, showcasing the seafood traditions of the Ionian coast.
Popular casual spot celebrated for Sicilian sandwiches, boards, and regional products, with a convivial atmosphere in Ortigia.
Established Ortigia restaurant known for refined Sicilian cuisine, fresh seafood, and an elegant atmosphere in a historic setting.
Established Ortigia venue offering creative Sicilian dishes with strong vegetarian and vegan options in a stylish contemporary space.
Moderate by Italian standards. Casual dining is affordable, while Ortigia hotels and seafood restaurants cost more in peak season.
Service is often included or modest. Tipping is not required, but leaving EUR 1-2 at cafes or 5-10% in restaurants for good service is appreciated. Round up taxis.
Official public transport app
Syracuse, Largo Aretusa -> Siracusa Railway Station
Find answers to the most common questions about traveling from Pisa to Syracuse by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Syracuse, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need