- Must visit
Paolo Orsi Regional Archaeological Museum
Sicily’s most important archaeological museum, with major collections from prehistoric to Greek and Roman Syracuse. A key stop for understanding the city’s ancient history.
Cheapest price
$24
Average price
$30
Fastest journey
5 h 1 m
Average duration
6 h 51 m
Trains per day
5
Distance
204 km
The best way to find a cheap train ticket from Palermo to Syracuse is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Syracuse will cost around $30 if you buy it on the day, but the cheapest tickets can be found for only $24.
It's difficult to get from Palermo to Syracuse without transferring at least once.
treno 5506 effettuato con bus PA318 · Regionale 5506 · Regionale 5385
treno 5520 effettuato con bus PA326 · Regionale 5520 · Regionale 5521
treno 5512 effettuato con bus PA324 · Regionale 5512 · Regionale 5397
Regionale 34862 · treno 5354 effettuato con bus PA408 · Regionale 21801
Regionale 5370+
Intercity 727
treno 5506 effettuato con bus PA318 · Regionale 5506 · Regionale 5385
treno 5512 effettuato con bus PA324 · Regionale 5512 · Regionale 5397
treno 5520 effettuato con bus PA326 · Regionale 5520 · Regionale 5521
Regionale 5370+
Intercity 727
Regionale 34862 · treno 5354 effettuato con bus PA408 · Regionale 21801Omio recommends booking the bus as it is the most popular option from Palermo to Syracuse among Omio's users. If you are prioritising price take the train with prices starting from $24. For those with little time consider booking a bus which can get you there in 4h 9m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a train costs an average of $24, and a bus costs an average of $19.
Distance: 126 miles (204 km)
| Train | Most popular Bus |
|---|---|
$25 Average price Cheapest | $30 Average price |
5h 27m Average total duration 4h 57m Onboard + 30m Additional time* | 4h 39m Average total duration Fastest 4h 9m Onboard + 30m Additional time* |
0.1 - 0.2kg CO2 emissions Lowest | 0.2 - 0.5kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Palermo to Syracuse:
A train is $5 (€4) less than a bus for this route with tickets for a bus from Palermo to Syracuse costing on average $30 (€25).
Other travel options to Syracuse take longer:
Train takes on average 4h 57m.
The table below shows live departures for Palermo to Syracuse trains for today, Saturday, June 20. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale Veloce 5360 · Regionale 22117 | 4:28 PM Palermo Centrale | 7h08 | 11:36 PM Syracuse station | 1 transfer | |
Regionale Veloce 5360+ Intercity 727 | 4:28 PM Palermo Centrale | 6h16 | 10:44 PM Syracuse station | 1 transfer | |
treno 5520 effettuato con bus PA326 · Regionale 5520 · Regionale 12989 | 5:02 PM Palermo Centrale | 4h36 | 9:38 PM Syracuse station | 2 transfers | |
| Sunday, June 21 | |||||
treno 5506 effettuato con bus PA318 · Regionale 5506 · Regionale 5385 | 7:02 AM Palermo Centrale | 5h01 | 12:03 PM Syracuse station | 2 transfers | |
Regionale 34862 · treno 5354 effettuato con bus PA408 · Regionale 21801 | 8:27 AM Palermo Centrale | 10h45 | 7:12 PM Syracuse station | 2 transfers | |
Regionale 5370+ Intercity 727 | 2:25 PM Palermo Centrale | 8h19 | 10:44 PM Syracuse station | 1 transfer | |
treno 5512 effettuato con bus PA324 · Regionale 5512 · Regionale 5397 | 3:02 PM Palermo Centrale | 5h04 | 8:06 PM Syracuse station | 2 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Palermo to Syracuse run on average 8 times per day, taking around 4h 57m. Cheap train tickets for this journey start at $24 (€20) but you can travel from only $19 (€16) by bus.
The earliest train runs at 03:17, the last at 21:53. The fastest train covers the 126 miles (204 km) distance in 4h 7m.
Distance 126 miles (204 km) |
Average train duration 4h 57m |
Cheapest ticket price $24 (€20) |
Trains per day 8 |
Fastest train 4h 7m |
First train 3:17 AM |
Last train 9:53 PM |
Cheapest Month Dec |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sat |
Best time to book 21 days |
Discover the best of Syracuse — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse trip today.
Sicily’s most important archaeological museum, with major collections from prehistoric to Greek and Roman Syracuse. A key stop for understanding the city’s ancient history.
An art museum in a historic palace on Ortigia, known for Sicilian medieval and Renaissance works, including Antonello da Messina’s Annunciation.
An interactive museum with models and reconstructions of inventions linked to Leonardo and Archimedes. Popular with families and visitors exploring Ortigia.
The historic heart of Syracuse, packed with sea views, Baroque lanes, markets, and major landmarks. The top area for walking, photography, and atmosphere.
Syracuse’s most celebrated square, framed by elegant Baroque buildings and the cathedral. A classic must-see and especially beautiful in the evening.
A freshwater spring beside the sea, linked to Greek myth and lined with papyrus plants. One of Ortigia’s most photographed corners.
A local pasta preparation often made with tomatoes, garlic, olive oil, breadcrumbs, and sometimes anchovies, reflecting the simple coastal flavors of Syracuse.
Traditional Sicilian pasta with sardines, wild fennel, pine nuts, and raisins; a classic sweet-savory dish widely associated with eastern Sicily.
Swordfish cooked in a rich sauce with tomatoes, capers, olives, and onions, showcasing the seafood traditions of the Ionian coast.
Popular casual spot celebrated for Sicilian sandwiches, boards, and regional products, with a convivial atmosphere in Ortigia.
Established Ortigia restaurant known for refined Sicilian cuisine, fresh seafood, and an elegant atmosphere in a historic setting.
Established Ortigia venue offering creative Sicilian dishes with strong vegetarian and vegan options in a stylish contemporary space.
Moderate by Italian standards. Casual dining is affordable, while Ortigia hotels and seafood restaurants cost more in peak season.
Service is often included or modest. Tipping is not required, but leaving EUR 1-2 at cafes or 5-10% in restaurants for good service is appreciated. Round up taxis.
Official public transport app
Syracuse, Largo Aretusa -> Siracusa Railway Station
Find answers to the most common questions about traveling from Palermo to Syracuse by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Syracuse, this guide helps you travel smarter and with confidence.

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