- Must visit
Paolo Orsi Regional Archaeological Museum
Leading archaeology museum with superb Greek and Roman finds, essential for understanding ancient Syracuse and eastern Sicily.
Cheapest price
$25
Average price
$33
Fastest journey
4 h 30 m
Average duration
4 h 57 m
Trains per day
15
Distance
204 km
The best way to find a cheap train ticket from Palermo to Syracuse is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Syracuse will cost around $33 if you buy it on the day, but the cheapest tickets can be found for only $25.
It's difficult to get from Palermo to Syracuse without transferring at least 2 times.
treno 5508 effettuato con bus PA320 · Regionale 5508 · Regionale Veloce 5391
treno 5512 effettuato con bus PA324 · Regionale 5512 · Regionale 12989
treno 5512 effettuato con bus PA324 · Regionale 5512 · Regionale Veloce 5397
treno 5506 effettuato con bus PA318 · Regionale 5506 · Regionale 5507
treno 5520 effettuato con bus PA326 · Regionale 5520 · Regionale 12989
treno 5520 effettuato con bus PA326 · Regionale 5520 · Regionale 12989
treno 5512 effettuato con bus PA324 · Regionale 5512 · Regionale Veloce 5397
treno 5508 effettuato con bus PA320 · Regionale 5508 · Regionale Veloce 5391
treno 5510 effettuato con bus PA322 · Regionale 5510 · Regionale 5399
treno 5506 effettuato con bus PA318 · Regionale 5506 · Regionale 5507Omio recommends booking the bus as it is the most popular option from Palermo to Syracuse among Omio's users. If you are prioritising price take the train with prices starting from $25. For those with little time consider booking a bus which can get you there in 4h 9m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a train costs an average of $25, and a bus costs an average of $19.
Distance: 126 miles (204 km)
| Train | Most popular Bus |
|---|---|
$25 Average price Cheapest | $30 Average price |
5h 27m Average total duration 4h 57m Onboard + 30m Additional time* | 4h 39m Average total duration Fastest 4h 9m Onboard + 30m Additional time* |
0.1 - 0.2kg CO2 emissions Lowest | 0.2 - 0.5kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Palermo to Syracuse:
A train is $5 (€4) less than a bus for this route with tickets for a bus from Palermo to Syracuse costing on average $30 (€25).
Other travel options to Syracuse take longer:
Train takes on average 4h 57m.
The table below shows live departures for Palermo to Syracuse trains for tomorrow, Wednesday, August 5. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 5352 · Regionale Veloce 5391 | 6:12 AM Palermo Centrale | 7h53 | 2:05 PM Syracuse station | 1 transfer | |
Intercity 736+ Regionale Veloce 5391 | 6:54 AM Palermo Centrale | 7h11 | 2:05 PM Syracuse station | 1 transfer | |
treno 5506 effettuato con bus PA318 · Regionale 5506 · Regionale 5507 | 7:02 AM Palermo Centrale | 5h09 | 12:11 PM Syracuse station | 2 transfers | |
Regionale 5354 · Regionale Veloce 5395 · Regionale 21789 | 8:10 AM Palermo Centrale | 8h59 | 5:09 PM Targia | 2 transfers | |
Regionale 5354 · Regionale Veloce 5395 | 8:10 AM Palermo Centrale | 8h00 | 4:10 PM Syracuse station | 1 transfer | |
treno 5508 effettuato con bus PA320 · Regionale 5508 · Regionale Veloce 5391 | 9:02 AM Palermo Centrale | 5h03 | 2:05 PM Syracuse station | 2 transfers | |
Intercity 730+ Regionale Veloce 5395 · Regionale 21789 | 10:00 AM Palermo Centrale | 7h09 | 5:09 PM Targia | 2 transfers | |
Intercity 730+ Regionale Veloce 5395 | 10:00 AM Palermo Centrale | 6h10 | 4:10 PM Syracuse station | 1 transfer | |
treno 5510 effettuato con bus PA322 · Regionale 5510 · Regionale 5399 | 1:02 PM Palermo Centrale | 5h04 | 6:06 PM Syracuse station | 2 transfers | |
Regionale 5358 · Regionale 12989 | 2:25 PM Palermo Centrale | 7h07 | 9:32 PM Syracuse station | 1 transfer | |
treno 5512 effettuato con bus PA324 · Regionale 5512 · Regionale 12989 | 3:02 PM Palermo Centrale | 6h30 | 9:32 PM Syracuse station | 2 transfers | |
treno 5512 effettuato con bus PA324 · Regionale 5512 · Regionale Veloce 5397 | 3:02 PM Palermo Centrale | 4h58 | 8:00 PM Syracuse station | 2 transfers | |
Regionale 5360 · Regionale 22117 | 4:35 PM Palermo Centrale | 6h55 | 11:30 PM Syracuse station | 1 transfer | |
Regionale 5360+ Intercity 727 | 4:35 PM Palermo Centrale | 6h03 | 10:38 PM Syracuse station | 1 transfer | |
treno 5520 effettuato con bus PA326 · Regionale 5520 · Regionale 12989 | 5:02 PM Palermo Centrale | 4h30 | 9:32 PM Syracuse station | 2 transfers | |
Find all the dates and times for this journey
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Trains from Palermo to Syracuse run on average 8 times per day, taking around 4h 57m. Cheap train tickets for this journey start at $25 (€20) but you can travel from only $19 (€16) by bus.
The earliest train runs at 03:17, the last at 21:53. The fastest train covers the 126 miles (204 km) distance in 4h 7m.
Distance 126 miles (204 km) |
Average train duration 4h 57m |
Cheapest ticket price $25 (€20) |
Trains per day 8 |
Fastest train 4h 7m |
First train 3:17 AM |
Last train 9:53 PM |
Cheapest Month Dec |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sat |
Best time to book 21 days |
Discover the best of Syracuse — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Syracuse trip today.
Leading archaeology museum with superb Greek and Roman finds, essential for understanding ancient Syracuse and eastern Sicily.
Gallery inside Palazzo Bellomo showing medieval and Baroque art, including Antonello da Messina's celebrated Annunciation.
Interactive science museum focused on Archimedes and Leonardo, engaging for families and visitors curious about inventions.
Syracuse's historic island center, packed with Baroque lanes, seafront walks, ancient ruins, and a vibrant local atmosphere.
Grand limestone square framed by the cathedral and palaces, one of Sicily's most elegant and memorable urban spaces.
Freshwater spring beside the sea linked to myth, famous for papyrus plants and its central place in Ortigia legends.
Pasta with fresh tomato sauce, fried eggplant, ricotta salata and basil. A classic Sicilian dish tied to nearby Catania and widely loved in Syracuse.
Rice balls stuffed with ragù, cheese or butter, then breaded and fried. A staple Sicilian street food eaten across Syracuse.
Small fried fish, often anchovies or whitebait, served simply with lemon. It reflects Syracuse's strong seafood tradition and daily catch.
Refined Michelin-starred dining on Ortigia with creative Sicilian tasting menus, elegant service and a romantic historic setting.
Historic market stop famous for sandwiches, charcuterie, cheese and quick Sicilian bites amid the bustling Ortigia food market.
Well-known Ortigia seafood restaurant serving local fish, pasta and Sicilian classics in a polished but relaxed atmosphere.
Moderate for Sicily. Dining and hotels are often cheaper than Rome or Milan, while summer stays in Ortigia and tourist dining can raise costs. Local buses are low cost.
Service is often included or minimal. Round up or leave 5-10% at restaurants for good service. Taxis are usually rounded up. In cafes, small change is enough.
Find answers to the most common questions about traveling from Palermo to Syracuse by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Syracuse, this guide helps you travel smarter and with confidence.

Here are some other resources that might have the information you need