- Must visit
Uffizi Galleries
World-famous museum of Renaissance art with masterpieces by Botticelli, Leonardo, Michelangelo, and Raphael. Timed entry is strongly advised due to very high demand.
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The cheapest and fastest trains from Chicago, IL to Florence, SC
Showing times and prices for Jun 21
Cheapest price
$443
Average price
$443
Fastest journey
1 d 8 h 30 m
Average duration
1 d 8 h 30 m
Trains per day
1
Distance
1095 km
Cheap tickets
The best way to find a cheap train ticket from Chicago, IL to Florence, SC is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Chicago, IL to Florence, SC will cost around $443 if you buy it on the day, but the cheapest tickets can be found for only $443.
Fast trains
It's difficult to get from Chicago, IL to Florence, SC without transferring at least once.
6:40 PM32h30Chicago, IL3:10 AMFlorence, SC$4431One-way1 transfer
- 6:40 PM32h30Chicago, IL3:10 AMFlorence, SC$4431One-way1 transfer
Travel Information
Compare train and bus for Chicago, IL to Florence, SC
Omio recommends booking the train as it is the most popular option from Chicago, IL to Florence, SC among Omio's users. If you are prioritising price take the bus with prices starting from $167. For those with little time consider booking a bus which can get you there in 23h 34m. The ticket price range depends on the travel mode: a bus costs an average of $167, and a train costs an average of $342.
Distance: 680 miles (1095 km)
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
$564 Average price | $214 Average price Cheapest | $168 Average price (fuel + tolls) |
25h 41m Average total duration 25h 11m Onboard + 30m Additional time* | 24h 4m Average total duration Fastest 23h 34m Onboard + 30m Additional time* | 13h 36m Average total duration (door-to-door) |
Most popular train company |  Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
The cheapest way to travel from Chicago, IL to Florence, SC is a bus with an average price of $214 (€175).
This is compared to other travel options from Chicago, IL to Florence, SC:
A bus is $350 (€287) less than a train for this route with tickets for a train from Chicago, IL to Florence, SC costing on average $564 (€462).
The fastest way to travel from Chicago, IL to Florence, SC is by bus with an average journey time of 23h 34m.
Other travel options to Florence, SC take longer:
Train takes on average 25h 11m.
It's helpful to compare your options as there are 2 ways to travel between Chicago, IL and Florence, SC including taking a train and bus.
We recommend using the train as it is the most popular way to get from Chicago, IL to Florence, SC among Omio's users.
Take the train. It's the cheaper option, and the extra time on board is usually more relaxing than driving it.
Tickets start at around $564 (€462) compared to roughly $168 (€138) in fuel and tolls — a saving of about $-396.04 (€-324.25). The journey takes 25h 11m versus 13h 36m by car, so you'll arrive a bit later, but you can work, read, or sleep along the way rather than spending the time behind the wheel. You'll also save the hassle of parking at the other end.
Driving is worth it if you're on a tight schedule, travelling as a group, or want to stop somewhere en route.
Live departures
Chicago, IL to Florence, SC train times
The table below shows live departures for Chicago, IL to Florence, SC trains for today, Saturday, June 20. You can also manually refresh the results below to see updated train journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| 11:40 PM Chicago, IL | 31h30 | 7:10 AM Florence, SC | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Chicago, IL to Florence, SC by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Jun 21
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Journey information
Overview: Train from Chicago, IL to Florence, SC
USAUSA
Trains from Chicago, IL to Florence, SC run on average 2 times per day, taking around 25h 11m. Cheap train tickets for this journey start at $342 (€280) but you can travel from only $167 (€136) by bus.
The earliest train runs at 17:55, the last at 23:32. The fastest train covers the 680 miles (1095 km) distance in 31h 30m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $167 (€136)
Distance 680 miles (1095 km) |
Average train duration 25h 11m |
Cheapest ticket price $342 (€280) |
Trains per day 2 |
Fastest train 31h 30m |
First train 5:55 PM |
Last train 11:32 PM |
Cheapest Month Dec |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Jul - Sep |
Best time to book 28 days |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $167 (€136)
Train companies: Amtrak from Chicago, IL to Florence, SC trainsAmtrak trains will get you between Chicago, IL and Florence, SC from $167 (€136). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Average Duration
31h 30m
Cheapest Price
$342 (€280)
Amtrak frequency
2 a day
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the train
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone
Complete guide to Florence
Things to do in Florence
Discover the best of Florence — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence trip today.
- Must visit
Accademia Gallery
Best known for Michelangelo’s David, this compact museum is one of Florence’s essential stops. Advance booking is commonly recommended because queues can be long.
- Recommended
Palazzo Pitti
Large palace museum complex with royal apartments, paintings, and design collections. Worth visiting for its scale, courtly interiors, and links to Medici history.
- Must visit
Piazza del Duomo
The monumental heart of Florence, surrounded by the cathedral, dome, baptistery, and bell tower. Essential for first-time visitors and classic city views.
- Must visit
Piazza della Signoria
Historic square lined with civic architecture and open-air sculptures. One of Florence’s liveliest public spaces and a key stop on any walking route.
- Must visit
Piazzale Michelangelo
The city’s most famous viewpoint, especially popular at sunset for sweeping skyline photos. A social media favorite and classic Florence panorama.
- Gluten-free
Pulled Pork Barbecue
Slow-smoked pork shoulder, usually chopped or pulled and served with a tangy Southern barbecue sauce. It is a staple across the Carolinas and common in Florence-area smokehouses.
Fried Catfish
Cornmeal-coated catfish fillets fried until crisp, often served with hush puppies and slaw. This is a classic Pee Dee and broader South Carolina comfort dish.
- Gluten-free
Shrimp And Grits
Creamy stone-ground grits topped with shrimp, often with bacon, gravy, or a light sauce. A defining Lowcountry and South Carolina dish regularly found in Florence.
Wholly Smokin' Downtown
Established downtown barbecue spot specializing in smoked meats, Southern sides, and a casual local atmosphere.
Victors
Upscale, long-running Florence restaurant known for steaks, seafood, and polished Southern-American dining in an elegant setting.
Tubb's Shrimp & Fish Co.
Well-known casual seafood restaurant recognized for fried seafood platters, shrimp, fish, and regional comfort fare.
United States Dollar
Costs are moderate for the U.S. Budget eats are easy to find, while hotels and fine dining can raise daily costs.
Average meal costs
- Budget
- USD 8-15 for fast food or a simple lunch.
- Mid-range
- USD 18-35 per person at a casual sit-down restaurant.
- Fine dining
- USD 50-100+ per person before drinks and tip.
- Coffee
- USD 3-6 for drip coffee or a latte.
Tipping culture
Tip 18-20% at restaurants. Tip USD 1-2 per drink at bars, round up or tip 10-15% for taxis, and tip hotel staff USD 2-5 for helpful service.
FAQs: Trains from Chicago, IL to Florence, SC
Find answers to the most common questions about traveling from Chicago, IL to Florence, SC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.
Train ticket prices from Chicago, IL to Florence, SC can vary. The cheapest ticket starts at $342 (€280), while the average price is around $564 (€462).
The train from Chicago, IL to Florence, SC takes 31h 30m and runs 2 per day.
The distance by train from Chicago, IL to Florence, SC is 680 miles (1095 km).
The first train from Chicago, IL to Florence, SC leaves at 5:55 PM.
The last train from Chicago, IL to Florence, SC leaves at 11:32 PM.
There is no high speed train available from Chicago, IL to Florence, SC.
There is no direct train service currently available from Chicago, IL to Florence, SC.
Unfortunately, there is no night train available from Chicago, IL to Florence, SC.
The train station in Chicago, IL that goes to Florence, SC is Chicago Union Station, Chicago, IL, which connects to Florence Station, Florence, SC.
The cheapest way to get from Chicago, IL to Florence, SC is by bus, with a cost of around $167 (€136).
The train journey from Chicago, IL to Florence, SC offers scenic views of the Midwest's fields and towns, transitioning into the lush greenery and gentle hills of the southeastern U.S., providing a diverse landscape experience.
A day trip from Chicago, IL to Florence, SC is not feasible as the journey duration is 31h 30m. The distance is 680 miles (1095 km). There are 2 trips per day available by train.
To fully explore Florence, SC, two to three days are recommended. This allows time to visit local attractions such as the Florence County Museum, War Between the States Museum, and enjoy the local dining and shopping experiences.
Yes, you can take the train from Chicago, IL to Florence, SC.
Since neither Chicago, IL nor Florence, SC are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
Popular day trips by train from Florence, SC include Charleston, SC, Kingstree, SC.
We recommend using the train as it is the most popular way to get from Chicago, IL to Florence, SC among Omio's users.
Items not allowed on trains typically include hazardous materials such as explosives, flammable liquids, corrosive substances, and illegal drugs. Additionally, large or bulky items that may obstruct aisles or emergency exits, as well as pets without proper carriers, may be restricted. Specific prohibited items can vary by train operator and region, so please check the rules for your particular journey.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Florence, SC, travelers should be cautious of petty crimes like pickpocketing and vehicle break-ins, especially in less crowded areas. It's advisable to stay in well-lit, populated places and avoid displaying valuables openly. Common scams include overcharging by taxi drivers and unofficial ticket sellers; always use licensed transportation and purchase tickets from authorized vendors. Staying aware of surroundings and securing personal belongings helps ensure a safe visit.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
popular train stations
Popular train stations from Chicago, IL to Florence, SC
Most Chicago, IL to Florence, SC trains use the Union Station to Florence Station station pair. Use this guide to compare Chicago, IL and Florence, SC train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Departure train stations in Chicago
Arrival train stations in Florence
Which Chicago, IL station do trains to Florence, SC leave from?
Trains from Chicago, IL to Florence, SC leave from Union Station. The station is 1 miles (3 km) from Chicago, IL city centre at 225 South Canal Street, Chicago, IL 60606, USA.
Union Station225 South Canal Street, Chicago, IL 60606, USA+1 800-872-7245
City-centre transport
Getting to Union Station from Chicago city centre
Union Station is 3 km from Chicago city centre. Public transport options include:
Bus28, 151 · 7m · $4 · every ~13 min
Union Station train station facilities and services
Union Station has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: The Chicago Firehouse Restaurant, Lou Mitchell's
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Union Station. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Union Station. Lost and found is available at the station.
Parking, taxis and toilets
Available at Union Station: Parking, Taxis, WC.
Bike and car services
Available at Union Station: Bike Parking, Car Rental.
Accessibility
Accessibility facilities are available at Union Station: Elevators, ramps, restrooms.
Shops, hotels and contact
Nearby hotels include The Kimpton Gray Hotel, JW Marriott Chicago, W Chicago - City Center.
Which Florence, SC station do trains from Chicago, IL arrive at?
Trains from Chicago, IL to Florence, SC arrive at Florence Station. Florence Station is 0 miles (1 km) from Florence, SC city centre.
Florence Station805 East Day Street, Florence, SC 29506, USA+1 800-872-7245
City-centre transport
Getting to Florence Station from Florence city centre
BusGreyhound services available nearby
Florence Station train station facilities and services
Florence Station has practical services for this route, including Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Information Desk, and Luggage Carts.
Food and drink
Food and drink options are available at Florence Station.
Tickets and information
Ticket office support is available at Florence Station. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Florence Station. Lost and found is available at the station.
Parking, taxis and toilets
Available at Florence Station: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Florence Station: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Aloft Florence, Hyatt Place Florence Downtown, Hotel Florence, Tapestry Collection by Hilton.
Most popular train connections from Chicago, IL
More options for your journey from Chicago, IL to Florence, SC
Here are some other resources that might have the information you need
Most popular trains to and from Florence, SC and Chicago, IL
Most popular train connections to Florence, SC
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