- Must visit
Uffizi Galleries
World-famous museum of Renaissance art with masterpieces by Botticelli, Leonardo, Michelangelo, and Raphael. Timed entry is strongly advised due to very high demand.
Omio recommends booking the bus as it is the most popular option from Jacksonville, NC to Florence, SC among Omio's users. If you are prioritising price take the bus with prices starting from $55. For those with little time consider booking a bus which can get you there in 23h 50m. The ticket price range depends on the travel mode: a bus costs an average of $55, and a bus costs an average of $55.
Distance: 138 miles (223 km)
Most popular Bus | Driving |
|---|---|
$60 Average price Cheapest | $32 Average price (fuel + tolls) |
24h 20m Average total duration Fastest 23h 50m Onboard + 30m Additional time* | 2h 52m Average total duration (door-to-door) |
Direct Options | Direct Options |
Other travel options to Florence, SC take longer:
Bus takes on average 23h 50m.
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Take a train from Jacksonville, NC to Florence, SC and enjoy the approximately 138 miles (223 km) long journey. Find schedules and pricing options for a convenient and affordable trip.
The earliest train runs at 10:54, the last at 10:54.
Distance 138 miles (223 km) |
Average train duration 5h 30m |
Trains per day 2 |
First train 10:54 AM |
Last train 10:54 AM |
High Season Apr - Jun |
Low Season Jan - Mar |
Discover the best of Florence — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Florence trip today.
World-famous museum of Renaissance art with masterpieces by Botticelli, Leonardo, Michelangelo, and Raphael. Timed entry is strongly advised due to very high demand.
Best known for Michelangelo’s David, this compact museum is one of Florence’s essential stops. Advance booking is commonly recommended because queues can be long.
Large palace museum complex with royal apartments, paintings, and design collections. Worth visiting for its scale, courtly interiors, and links to Medici history.
The monumental heart of Florence, surrounded by the cathedral, dome, baptistery, and bell tower. Essential for first-time visitors and classic city views.
Historic square lined with civic architecture and open-air sculptures. One of Florence’s liveliest public spaces and a key stop on any walking route.
The city’s most famous viewpoint, especially popular at sunset for sweeping skyline photos. A social media favorite and classic Florence panorama.
Slow-smoked pork shoulder, usually chopped or pulled and served with a tangy Southern barbecue sauce. It is a staple across the Carolinas and common in Florence-area smokehouses.
Cornmeal-coated catfish fillets fried until crisp, often served with hush puppies and slaw. This is a classic Pee Dee and broader South Carolina comfort dish.
Creamy stone-ground grits topped with shrimp, often with bacon, gravy, or a light sauce. A defining Lowcountry and South Carolina dish regularly found in Florence.
Established downtown barbecue spot specializing in smoked meats, Southern sides, and a casual local atmosphere.
Upscale, long-running Florence restaurant known for steaks, seafood, and polished Southern-American dining in an elegant setting.
Well-known casual seafood restaurant recognized for fried seafood platters, shrimp, fish, and regional comfort fare.
Costs are moderate for the U.S. Budget eats are easy to find, while hotels and fine dining can raise daily costs.
Tip 18-20% at restaurants. Tip USD 1-2 per drink at bars, round up or tip 10-15% for taxis, and tip hotel staff USD 2-5 for helpful service.
Find answers to the most common questions about traveling from Jacksonville, NC to Florence, SC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

Most Jacksonville, NC to Florence, SC trains use the Swansboro to Florence Station station pair. Use this guide to compare Jacksonville, NC and Florence, SC train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Florence Station has practical services for this route, including Lockers, Parking, Dining, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Information Desk, and Luggage Carts.
Food and drink options are available at Florence Station.
Ticket office support is available at Florence Station. Information desks are located in the main hall.
Luggage storage is available at Florence Station. Lost and found is available at the station.
Available at Florence Station: Parking, Taxis, WC.
Accessibility facilities are available at Florence Station: Elevators, ramps.
Nearby hotels include Aloft Florence, Hyatt Place Florence Downtown, Hotel Florence, Tapestry Collection by Hilton.
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