Harrisburg, PA to Florence, SC train with Amtrak

Fri, Mar 20
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Amtrak
Regionale
Deutsche Bahn
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Frecciarossa
2,000+ travel companies
Amtrak
Regionale
Deutsche Bahn
iryo
Frecciarossa
2,000+ travel companies
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Travel Information

Compare train and bus for Harrisburg, PA to Florence, SC

Omio recommends booking the train as it is the most popular option from Harrisburg, PA to Florence, SC among Omio's users. If you are prioritising price take the train with prices starting from $194. For those with little time consider booking a train which can get you there in 12h 8m. The ticket price range depends on the travel mode: a train costs an average of $194, and a bus costs an average of $183.

Distance: 448 miles (722 km)

Compare train with

Most popular
Train
Bus

$223

Average price

Cheapest

$232

Average price

12h 38m

Average total duration

Fastest

12h 8m

Onboard

+

30m

Additional time*

24h 23m

Average total duration

23h 53m

Onboard

+

30m

Additional time*

Direct Options

Direct Options

Compare prices and tickets Harrisburg, PA to Florence, SC by train or bus

Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Journey information

Overview: Train from Harrisburg, PA to Florence, SC

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Trains from Harrisburg, PA to Florence, SC run on average 2 times per day, taking around 12h 8m. Cheap train tickets for this journey start at $194 (€157) but you can travel from only $183 (€148) by bus.

The earliest train runs at 05:00, the last at 23:32. The fastest train covers the 448 miles (722 km) distance in 12h 52m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $183 (€148)
Distance
448 miles (722 km)
Average train duration
12h 8m
Cheapest ticket price
$194 (€157)
Trains per day
2
Fastest train
12h 52m
First train
05:00
Last train
23:32
Cheapest month
Dec
Cheapest day
Thu
High season
Jan - Mar
Low season
Jan - Mar
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from $183 (€148)

Train companies: Amtrak from Harrisburg, PA to Florence, SC trainsAmtrak trains will get you between Harrisburg, PA and Florence, SC from $183 (€148). With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Amtrak

About
Amtrak is the main passenger train operator in the United States, providing medium- and long-distance intercity services across 46 states and three Canadian provinces. Operating over 300 trains daily and serving more than 500 destinations, Amtrak connects cities and regions nationwide through routes such as the high-speed Acela in the Northeast Corridor, the scenic Coast Starlight along the West Coast, and the Empire Builder linking Chicago to the Midwest and the Pacific Northwest. Other notable services include the Northeast Regional, Keystone Service, and the unique Auto Train, which allows passengers to bring their cars onboard. Amtrak offers a variety of classes to suit different budgets and travel needs, including Coach, Business, First Class, and Sleeper Class with options like Roomettes, Bedrooms, and Bedroom Suites for overnight journeys. Ticket types include Saver, Value, Flexible, Business, and Premium. Onboard amenities vary by service but may include comfortable seating, Wi-Fi, power outlets, dining options, and lounge access on select trains. Popular routes include Washington, D.C.–Boston, San Diego–San Luis Obispo, San Jose–Sacramento, and Chicago–Seattle.
Luggage & cancellation policy
Average Duration
12h 52m
Cheapest Price
$194 (€157)
Amtrak frequency
2 a day
Luggage included
2 personal items and 2 carry-on bags included free
Luggage storage
Overhead racks, under seats, and designated luggage areas at end of cars
Cancellation Policy
Cancellation policies depend on ticket type and timing
Refund
Full refund if train is canceled by Amtrak
Amenities on board the train
Wifi
Food sold onboard
Café car with snacks, beverages, and light meals. Long-distance trains have full-service dining cars
Seat reservation
Included in ticket price for Business and First Class. Optional fee for Coach Class
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible restrooms, Red Cap assistance service, accessible platforms and stations
Pets
Small pets under 20 pounds allowed for $26 fee. Must be in carrier. Service animals travel free
Quiet zone

FAQs: Trains from Harrisburg, PA to Florence, SC

Find answers to the most common questions about traveling from Harrisburg, PA to Florence, SC by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Florence, SC, this guide helps you travel smarter and with confidence.

FAQs
Train ticket prices from Harrisburg, PA to Florence, SC can vary. The cheapest ticket starts at $194 (€157), while the average price is around $223 (€181).
The train from Harrisburg, PA to Florence, SC takes 12h 52m and runs 2 per day.
The first train from Harrisburg, PA to Florence, SC leaves at 5:00 AM.
The distance by train from Harrisburg, PA to Florence, SC is 448 miles (722 km).
The last train from Harrisburg, PA to Florence, SC leaves at 11:32 PM.
There is no high speed train available from Harrisburg, PA to Florence, SC.
There is no direct train service currently available from Harrisburg, PA to Florence, SC.
Unfortunately, there is no night train available from Harrisburg, PA to Florence, SC.
The train station in Harrisburg, PA that goes to Florence, SC is Harrisburg Station, Harrisburg, PA, which connects to Florence Station, Florence, SC.
The cheapest way to get from Harrisburg, PA to Florence, SC is by bus, with a cost of around $183 (€148).
The train journey from Harrisburg, PA to Florence, SC offers a mix of urban and rural scenery, with views of rolling hills, small towns, and stretches of countryside, though it is not particularly renowned for being scenic.
A day trip from Harrisburg, PA to Florence, SC is not feasible as the journey takes 12h 52m and covers a distance of 448 miles (722 km). Additionally, the frequency is 2 trips per day for trains.
To fully explore Florence, SC, two to three days are recommended. This allows time to visit local attractions such as the Florence County Museum, War Between the States Museum, and enjoy the local dining and shopping experiences.
Yes, you can take the train from Harrisburg, PA to Florence, SC.

popular train stations

Popular train stations from Harrisburg, PA to Florence, SC

Harrisburg
Florence
The major train station for departures in Harrisburg is Harrisburg Station. Find all the information you need to know about services, amenities and connections at Harrisburg Station for your trip from Harrisburg to Florence.
Harrisburg StationWifiLockersParkingDiningATMTaxisAccessibilityWCHotelLost and Found OfficeTicket OfficeBike ParkingCar RentalInformation DeskLuggage Carts
Amenities at train station
WifiWifi
LockersLockers
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Lost and Found OfficeLost and Found Office
Ticket OfficeTicket Office
Bike ParkingBike Parking
Car RentalCar Rental
Information DeskInformation Desk
Luggage CartsLuggage Carts
information
phone
Phone Number
ticketOfficeHours
Ticket Office Hours
  • 6:00 AM - 10:00 PM Monday - Sunday
ticketOfficeHours
Distance to city center
1 km
platformCount
Number of platforms
5
Wifi
Wifi
  • Free
Parking
Parking
  • Parking available on-site with both short-term and long-term options.
Dining
Dining
  • The Millworks
  • Bricco
Taxis
Taxis
  • Outside the main entrance.
Accessibility
Accessibility
  • Elevators, ramps, restrooms.
WC
WC
  • $0.50
Hotel
Hotel
  • Hilton Harrisburg
  • Crowne Plaza Harrisburg-Hershey
  • Radisson Hotel Harrisburg
Lost and Found Office
Lost and Found Office
  • Located in the main hall
Car Rental
Car Rental
  • Enterprise
  • Hertz
Information Desk
Information Desk
  • Located in the main hall
Luggage Carts
Luggage Carts
  • Free
Station Plan
  • Hall 1: main entrance, ticket office, and waiting area
  • Hall 2: platforms for Amtrak and regional trains
  • Hall 3: bus connections and car rental services
Public transit options for Harrisburg Station
  • Bus: CAT (Capital Area Transit) services available
  • Greyhound and other intercity bus services

More options for your journey from Harrisburg, PA to Florence, SC

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