- Must visit
Saint Louis Art Museum
Major fine arts museum in Forest Park with a strong encyclopedic collection spanning ancient to contemporary works. A top cultural stop in the city.
Omio recommends booking the bus as it is the most popular option from Tempe, AZ to St. Louis, MO among Omio's users. If you are prioritising price take the bus with prices starting from $179. For those with little time consider booking a flight which can get you there in 2h 58m. The ticket price range depends on the travel mode: a bus costs an average of $179, and a flight costs an average of $452.
Distance: 1262 miles (2031 km)
Most popular Bus | Flight |
|---|---|
$179 Average price Cheapest | $452 Average price |
30h 55m Average total duration 30h 25m Onboard + 30m Additional time* | 5h 58m Average total duration Fastest 2h 58m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
This is compared to other travel options from Tempe, AZ to St. Louis, MO:
A bus is $274 (€225) less than a flight for this route with tickets for a flight from Tempe, AZ to St. Louis, MO costing on average $452 (€372).
Other travel options to St. Louis, MO take longer:
Bus takes on average 30h 25m.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:45AM | Arrival Time 01:10PM | Duration 30h25 | Departure days Sat | Cheapest price $179 |
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Tempe, AZ to St. Louis, MO run on average 11 times per day, taking around 30h 25m. Cheap bus tickets for this journey start at $179 (€147) if you book in advance.
There are 6 buses per day. The earliest bus runs at 01:20, the last at 19:42. The fastest bus covers the 1262 miles (2031 km) distance in 30h 25m.
Distance 1262 miles (2031 km) |
Average bus duration 30h 25m |
Cheapest ticket price $179 (€147) |
Buses per day 11 |
Direct buses 6 |
Fastest bus 30h 25m |
First bus 1:20 AM |
Last bus 7:42 PM |
Cheapest Month Jun |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jan - Mar |
Discover the best of St. Louis — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect St. Louis trip today.
Major fine arts museum in Forest Park with a strong encyclopedic collection spanning ancient to contemporary works. A top cultural stop in the city.
Highly original artist-built museum and playground inside a former warehouse, known for tunnels, slides, rooftop features, and immersive installations.
History museum in Forest Park covering St. Louis, Missouri, and regional stories through accessible permanent and temporary exhibitions.
One of the largest urban parks in the United States, home to major cultural institutions, lakes, trails, and broad green space.
Walkable neighborhood known for handsome architecture, lively streets, and a strong mix of shops, culture, and city atmosphere.
Popular entertainment corridor with street life, public art, music history, and a strong local identity near Washington University.
A thin, cracker-like crust pizza cut into squares and traditionally topped with Provel cheese. It is one of the city’s most iconic local foods.
Breaded and fried meat- or cheese-filled ravioli, usually served with marinara. This St. Louis specialty is a classic appetizer across the city.
A rich, dense cake with a buttery base and sweet, gooey topping. It is a beloved St. Louis dessert found in bakeries throughout the region.
Legendary dessert stand serving frozen custard concretes and sundaes; a must-visit local institution with nostalgic charm.
Popular barbecue spot known for Memphis-style smoked ribs, pulled pork, and brisket in a lively casual setting.
Established Italian restaurant in the historic Hill neighborhood, famous for toasted ravioli, pasta, and classic old-school hospitality.
Generally moderate for U.S. city travel. Hotels vary, while casual dining, coffee, and local transport are fairly manageable.
Tip 18-20% at restaurants; 20%+ for great service. Tip bartenders USD 1-2 per drink, taxis about 10-15%, and round up for casual service.
Find answers to the most common questions about traveling from Tempe, AZ to St. Louis, MO by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at St. Louis, MO, this guide helps you travel smarter and with confidence.

Most Tempe, AZ to St. Louis, MO buses use the Mesa, South Country Club Drive (Greyhound Bus Station) to St. Louis, S 15th St (Civic center) station pair, with some services arriving at St. Louis, Lambert International Airport. Use this guide to compare Tempe, AZ and St. Louis, MO bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
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