The cheapest and fastest buses from Tampa, FL to Key West, FL
Cheapest price
$53
Average price
$53
Fastest journey
17 h 10 m
Average duration
17 h 10 m
Buses per day
1
Distance
383 km
The best way to find a cheap bus ticket from Tampa, FL to Key West, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Tampa, FL to Key West, FL will cost around $53 if you buy it on the day, but the cheapest tickets can be found for only $53.
Of the 1 buses that leave Tampa, FL for Key West, FL on Thu, Jan 15, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Jan 15 the direct buses cover the 383 km distance in an average of 17 h 10 m but if you time it right, some buses will get you there in just 17 h 10 m .
On Thu, Jan 15 the slowest buses will take 17 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare bus and flight for Tampa, FL to Key West, FL
Omio recommends booking the bus as it is the most popular option from Tampa, FL to Key West, FL among Omio's users. If you are prioritising price take the bus with prices starting from €42. For those with little time consider booking a flight which can get you there in 1h 4m. The ticket price range depends on the travel mode: a bus costs an average of €42, and a flight costs an average of €49.
Distance: 237 miles (383 km)
Compare bus with
Most popular Bus | Flight |
|---|---|
€59 Average price Cheapest | €79 Average price |
12h 25m Average total duration 11h 55m Onboard + 30m Additional time* | 4h 4m Average total duration Fastest 1h 4m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Live departures
Tampa, FL to Key West, FL bus times
The table below shows live departures for Tampa, FL to Key West, FL buses for today, Wednesday, January 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:40 PM Tampa, FL | 15h50 | 1:30 PM Key West, FL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Tampa, FL to Key West, FL by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jan 15
Jan 16
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Jan 19
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Jan 21
Journey information
Overview: Bus from Tampa, FL to Key West, FL
Buses from Tampa, FL to Key West, FL run on average 4 times per day, taking around 11h 55m. Cheap bus tickets for this journey start at $53 (€42) if you book in advance.
The earliest bus runs at 09:30, the last at 17:00. The fastest bus covers the 237 miles (383 km) distance in 15h 35m.
Distance 237 miles (383 km) |
Average bus duration 11h 55m |
Cheapest ticket price $53 (€42) |
Buses per day 4 |
Fastest bus 15h 35m |
First bus 09:30 |
Last bus 17:00 |
Bus providers: FlixBus from Tampa, FL to Key West, FLYou can travel by bus between Tampa, FL to Key West, FL with FlixBus for as low as $53 (€42). When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Tampa, FL to Key West, FL
Find answers to the most common questions about traveling from Tampa, FL to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.

- Ernest Hemingway Home and Museum, the former residence of the famous author featuring guided tours and a colony of six-toed cats
- Key West Butterfly and Nature Conservatory, a lush habitat housing hundreds of butterflies and exotic birds
- Fort Zachary Taylor Historic State Park, a Civil War-era fort offering beach access, snorkeling, and picnic areas
- Mallory Square, a waterfront plaza known for its nightly sunset celebrations and street performances
- Key West Lighthouse and Keeper's Quarters Museum, offering panoramic views of the island and insights into maritime history.
- Duval Street, stroll along the vibrant street lined with shops, bars, and restaurants
- Dry Tortugas National Park, visit the remote park known for its historic fort and snorkeling opportunities
- Southernmost Point Buoy, take a photo at the iconic landmark marking the southernmost point in the continental USA
- Key West Ghost and Mysteries Tour, embark on a guided tour exploring the haunted history of the island
- Fury Water Adventures, enjoy a variety of water sports including snorkeling, parasailing, and sunset cruises.
To find the cheapest bus tickets for your trip from Tampa, FL to Key West, FL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
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Popular bus stations from Tampa, FL to Key West, FL
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