Tampa, FL to Key West, FL bus with Greyhound

Thu, Sep 17
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The cheapest and fastest buses from Tampa, FL to Key West, FL

Showing times, prices and bookable tickets for Sep 17

Cheapest price on Sep 17

$58

Average ticket price on Sep 17

$64

Fastest journey on Sep 17

13 h 55 m

Average journey duration on Sep 17

15 h 36 m

Buses on Sep 17

4

Distance

383 km

Cheap tickets

The best way to find a cheap bus ticket from Tampa, FL to Key West, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Tampa, FL to Key West, FL will cost around $64 if you buy it on the day, but the cheapest tickets can be found for only $58.

Fast buses

It's difficult to get from Tampa, FL to Key West, FL without transferring at least once.

  • FlixBusFlixBus+Greyhound ·
    4:00 PM17h30
    Tampa, Marion Transit Center
    9:30 AMKey West, South Roosevelt Boulevard (Key West International Airport), FL
    $581One-way
    2 transfers
  • FlixBusFlixBus+Greyhound ·
    4:35 PM16h55
    Tampa, USF Holly Drive (Central Plant), FL
    9:30 AMKey West, South Roosevelt Boulevard (Key West International Airport), FL
    $581One-way
    2 transfers
  • FlixBusFlixBus+Greyhound
    10:35 PM13h55
    Tampa, Marion Transit Center
    12:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FL
    $691One-way
    1 transfer
  • FlixBusFlixBus · FlixBus+Greyhound
    10:25 PM14h05
    Tampa, USF Holly Drive (Central Plant), FL
    12:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FL
    $711One-way
    2 transfers

Travel Information

Compare bus and flight for Tampa, FL to Key West, FL

Omio recommends booking the flight as it is the most popular option from Tampa, FL to Key West, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $79 For those with little time, consider booking a flight, which has an average total journey time of 6h 15m. Average ticket prices depend on the travel mode: a bus costs an average of $79, while a flight costs an average of $714.

Distance: 237 miles (383 km)

Compare bus with

Bus
Most popular
Flight
Driving

$79

Average price

Cheapest

$714

Average price

$81

Average price

(fuel + tolls)

12h 14m

Average total duration

11h 44m

Onboard

+

30m

Additional time*

6h 15m

Average total duration

Fastest

4h 15m

Onboard

+

2h 0m

Additional time*

7h 9m

Average total duration

(door-to-door)

Greyhound

Most popular bus company

American Airlines

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Tampa, FL to Key West, FL is a bus with an average price of $79.

This is compared to other travel options from Tampa, FL to Key West, FL:

A bus is $635 less than a flight for this route with tickets for a flight from Tampa, FL to Key West, FL costing on average $714.

The fastest way to travel from Tampa, FL to Key West, FL is by flight with an average journey time of 4h 15m.

Other travel options to Key West, FL take longer:

Bus takes on average 11h 44m.

It's helpful to compare your options as there are 2 ways to travel between Tampa, FL and Key West, FL including taking a bus and flight.
We recommend using the flight as it is the most popular way to get from Tampa, FL to Key West, FL among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $79 compared to roughly $81 in fuel and tolls — a saving of about $2. The journey takes 11h 44m versus 7h 9m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Tampa, FL to Key West, FL Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
Greyhound
Departure Time
04:00PM
Arrival Time
09:30AM
Duration
17h30
Departure days
Mon, Tue, Wed, Thu, Fri, Sat
Cheapest price
$54
Operator
Greyhound
Departure Time
04:35PM
Arrival Time
09:30AM
Duration
16h55
Departure days
Mon, Tue, Wed, Thu, Fri, Sat
Cheapest price
$55
Operator
Greyhound
Departure Time
04:55PM
Arrival Time
09:30AM
Duration
16h35
Departure days
Sun
Cheapest price
$58
Operator
Greyhound
Departure Time
05:25PM
Arrival Time
09:30AM
Duration
16h05
Departure days
Sun
Cheapest price
$59
Operator
FlixBus
Departure Time
10:25PM
Arrival Time
12:30PM
Duration
14h05
Departure days
Mon, Thu, Fri, Sat, Sun
Cheapest price
$64
Operator
Greyhound
Departure Time
10:25PM
Arrival Time
03:30PM
Duration
17h05
Departure days
Wed
Cheapest price
$56
Operator
FlixBus
Departure Time
10:35PM
Arrival Time
03:30PM
Duration
16h55
Departure days
Everyday
Cheapest price
$57

Live departures

Tampa, FL to Key West, FL bus times

The table below shows live departures for Tampa, FL to Key West, FL buses for today, Wednesday, September 16. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBusFlixBus+Greyhound · 10:25 PM Tampa, USF Holly Drive (Central Plant), FL
17h05
3:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL2 transfers
FlixBusFlixBus+Greyhound10:35 PM Tampa, Marion Transit Center
16h55
3:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL1 transfer
Thursday, September 17
FlixBusFlixBus+Greyhound · 4:00 PM Tampa, Marion Transit Center
17h30
9:30 AM Key West, South Roosevelt Boulevard (Key West International Airport), FL2 transfers
FlixBusFlixBus+Greyhound · 4:35 PM Tampa, USF Holly Drive (Central Plant), FL
16h55
9:30 AM Key West, South Roosevelt Boulevard (Key West International Airport), FL2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Tampa, FL to Key West, FL by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Sep 17
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Why should you book Tampa, FL to Key West, FL buses with Omio?

Greyhound as well as FlixBus offer buses services from Tampa, FL to Key West, FL.
Omio is an official ticket reseller for all your travel options from Tampa, FL to Key West, FL.

Why book with Omio vs Greyhound?

  • Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of FlixBus to find the best option for your trip from Tampa, FL to Key West, FL.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Tampa, FL to Key West, FL.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Tampa, FL to Key West, FL.
  • Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Tampa, FL to Key West, FL.

Journey information

Overview: Bus from Tampa, FL to Key West, FL

USAUSA
USAUSA
Icon of bus

Buses from Tampa, FL to Key West, FL run on average 4 times per day, taking around 11h 44m. Cheap bus tickets for this journey start at $56 if you book in advance.

The earliest bus runs at 10:00, the last at 22:35. The fastest bus covers the 237 miles (383 km) distance in 11h 0m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
237 miles (383 km)
Average bus duration
11h 44m
Cheapest ticket price
$56
Buses per day
4
Fastest bus
11h 0m
First bus
10:00 AM
Last bus
10:35 PM
Cheapest Month
Oct
Cheapest Day
Sun
High Season
Jul - Sep
Low Season
Oct - Dec
Busiest Day
Thu
Least Busy Day
Thu
Best time to book
35 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: Greyhound, FlixBus from Tampa, FL to Key West, FLYou can travel by bus between Tampa, FL to Key West, FL with Greyhound, FlixBus for as low as $74. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
11h 50m
Cheapest FlixBus Price
$61
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
11h 0m
Cheapest Greyhound Price
$56
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from Tampa, FL to Key West, FL

Find answers to the most common questions about traveling from Tampa, FL to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Tampa, FL to Key West, FL can start from as little as $56 when you book in advance. The average bus ticket price for Tampa, FL to Key West, FL is $79 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Tampa, FL to Key West, FL is 11h 0m to travel the 237 miles (383 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Tampa, FL to Key West, FL leaves at 10:00 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Tampa, FL to Key West, FL leaves at 10:35 PM.
There are 4 buses a day from Tampa, FL to Key West, FL which require at least one change with Greyhound, FlixBus. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Tampa, FL to Key West, FL, you can count on Greyhound, FlixBus for the best way to get you to Key West, FL. You can also check all possible bus companies who offer a service between Tampa, FL and Key West, FL and compare the amenities they offer before buying a bus ticket.
When departing from Tampa, FL , you have various bus station options to start your journey from including Tampa, Marion Transit Center, Tampa, USF Holly Drive (Central Plant), FL, Saint Petersburg, Central Avenue N / Dr Martin Luther King St Jr, FL . When arriving in Key West, FL , you can end your journey in bus stations like Key West, South Roosevelt Boulevard (Key West International Airport), FL .Passengers board the bus most frequently from Tampa, Marion Transit Center, which is located around away from the city centre, and they get off the bus at Key West, South Roosevelt Boulevard (Key West International Airport), FL, located 2 away from the city centre.
A trip to Key West, FL from Tampa, FL is worth doing but not as a day trip with a journey time of 11h 0m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Tampa, FL to Key West, FL is October.
It's helpful to compare your options as there are 2 ways to travel between Tampa, FL and Key West, FL including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Tampa, FL to Key West, FL:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Tampa, FL to Key West, FL for bus company Greyhound, FlixBus.
Some of the most interesting sights to explore in Key West, FL are:
  • Ernest Hemingway Home and Museum, the former residence of the famous author featuring guided tours and a colony of six-toed cats
  • Key West Butterfly and Nature Conservatory, a lush habitat housing hundreds of butterflies and exotic birds
  • Fort Zachary Taylor Historic State Park, a Civil War-era fort offering beach access, snorkeling, and picnic areas
  • Mallory Square, a waterfront plaza known for its nightly sunset celebrations and street performances
  • Key West Lighthouse and Keeper's Quarters Museum, offering panoramic views of the island and insights into maritime history.
The best things to do in Key West, FL include:
  • Duval Street, stroll along the vibrant street lined with shops, bars, and restaurants
  • Dry Tortugas National Park, visit the remote park known for its historic fort and snorkeling opportunities
  • Southernmost Point Buoy, take a photo at the iconic landmark marking the southernmost point in the continental USA
  • Key West Ghost and Mysteries Tour, embark on a guided tour exploring the haunted history of the island
  • Fury Water Adventures, enjoy a variety of water sports including snorkeling, parasailing, and sunset cruises.
Whether you can cancel your bus ticket from Tampa, FL to Key West, FL depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company Greyhound, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Tampa, FL to Key West, FL.
Yes, the following luggage options are included when booking a bus ticket from Tampa, FL to Key West, FL:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Tampa, FL to Key West, FL:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Tampa, FL to Key West, FL. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Tampa, FL to Key West, FL with the following bus company: Greyhound, FlixBus
Yes, there are USB plugs on board the bus from Tampa, FL to Key West, FL with the following bus company: Greyhound, FlixBus.
Yes, there is Wifi on board the bus from Tampa, FL to Key West, FL with the following bus company: Greyhound, FlixBus.
Since neither Tampa, FL nor Key West, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the flight as it is the most popular way to get from Tampa, FL to Key West, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Key West, FL, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Duval Street. Common scams include overpriced taxi rides and timeshare presentations that pressure visitors into purchases. It's advisable to use licensed transportation and be vigilant with personal belongings to stay safe.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Tampa, FL to Key West, FL

Most Tampa, FL to Key West, FL buses use the Tampa, Marion Transit Center to Key West, South Roosevelt Boulevard (Key West International Airport) station pair. Use this guide to compare Tampa, FL and Key West, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Tampa
Arrival bus stations in Key West

Which Tampa, FL station do buses to Key West, FL leave from?

Buses from Tampa, FL to Key West, FL leave from Tampa, Marion Transit Center. The station is 0 miles (1 km) from Tampa, FL city centre at Marion Transit Center, 1211 N Marion St, Tampa, FL 33602, USA.
Tampa, Marion Transit CenterMarion Transit Center, 1211 N Marion St, Tampa, FL 33602, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Tampa, Marion Transit Center from Tampa city centre

Bus1, 5, 19, 30 · 3m · $5 · every ~15 min

Tampa, Marion Transit Center bus station facilities and services

Tampa, Marion Transit Center has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Tampa, Marion Transit Center. ATMs are available at Tampa, Marion Transit Center.

Tickets and information

Ticket office support is available at Tampa, Marion Transit Center.

Parking, taxis and toilets

Available at Tampa, Marion Transit Center: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Tampa, Marion Transit Center: Wheelchair accessible with ramps.

Tampa, USF Holly Drive (Central Plant)University of South Florida, Central Plant, 13302 USF Chestnut Dr, Tampa, FL 33620, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Tampa, USF Holly Drive (Central Plant) from Tampa city centre

Tampa, USF Holly Drive (Central Plant) is 13 km from Tampa city centre. Public transport options include:

BusFlixBus 2421 · 26m · $1
9, 400 · 1h 3m · $5 · every ~7 min
6 · 1h 9m · $5 · every ~5 min

Tampa, USF Holly Drive (Central Plant) bus station facilities and services

Tampa, USF Holly Drive (Central Plant) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Tampa, USF Holly Drive (Central Plant). ATMs are available at Tampa, USF Holly Drive (Central Plant).

Tickets and information

Ticket office support is available at Tampa, USF Holly Drive (Central Plant).

Parking, taxis and toilets

Available at Tampa, USF Holly Drive (Central Plant): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Tampa, USF Holly Drive (Central Plant): Wheelchair accessible facilities.

More options for your journey from Tampa, FL to Key West, FL

Here are some other resources that might have the information you need

Return journeys for buses from Key West, FL to Tampa, FL
Flights from Tampa, FL to Key West, FL
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Tickets and more information for coaches to Key West, FL

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