- Must visit
Ernest Hemingway Home and Museum
The Ernest Hemingway Home and Museum lets visitors tour the writer's residence, gardens, and rooms tied to his Key West years.
2,000+ travel companies
2,000+ travel companies
Scan to get our free app
Use our app to get live travel updates and book mobile tickets for trains, buses, flights, and ferries.
App Store
4.942K ratings
Google Play
4.6136K reviews
The cheapest and fastest buses from Orlando, FL to Key West, FL
Showing times, prices and bookable tickets for Nov 01
- Cheapest price on Nov 01
- €64
- Average ticket price on Nov 01
- €71
- Fastest journey on Nov 01
- 9 h 40 m
- Average journey duration on Nov 01
- 11 h 3 m
- Buses on Nov 01
- 5
- Distance
- 445 km
Cheap tickets
The best way to find a cheap bus ticket from Orlando, FL to Key West, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Key West, FL will cost around €71 if you buy it on the day, but the cheapest tickets can be found for only €64.
Fast buses
It's difficult to get from Orlando, FL to Key West, FL without transferring at least once.
FlixBus+
5:50 AM 9h40 Orlando, The Florida Mall, FL 3:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL €64 1 One-way 1 transfer- FlixBus+
5:20 AM 10h10 Orlando, N John Young Pkwy (Greyhound Bus Station) 3:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL €65 1 One-way 1 transfer - FlixBus+
12:45 AM 12h45 Orlando, N John Young Pkwy (Greyhound Bus Station) 12:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL €68 1 One-way 1 transfer - FlixBus+
1:15 AM 12h15 Orlando, The Florida Mall, FL 12:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL €69 1 One-way 1 transfer - ·
11:05 PM 10h25 Orlando, N John Young Pkwy (Greyhound Bus Station) 9:30 AM Key West, South Roosevelt Boulevard (Key West International Airport), FL €89 1 One-way 1 transfer
- FlixBus+
5:50 AM 9h40 Orlando, The Florida Mall, FL 3:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL €64 1 One-way 1 transfer - FlixBus+
5:20 AM 10h10 Orlando, N John Young Pkwy (Greyhound Bus Station) 3:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL €65 1 One-way 1 transfer - ·
11:05 PM 10h25 Orlando, N John Young Pkwy (Greyhound Bus Station) 9:30 AM Key West, South Roosevelt Boulevard (Key West International Airport), FL €89 1 One-way 1 transfer - FlixBus+
1:15 AM 12h15 Orlando, The Florida Mall, FL 12:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL €69 1 One-way 1 transfer - FlixBus+
12:45 AM 12h45 Orlando, N John Young Pkwy (Greyhound Bus Station) 12:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL €68 1 One-way 1 transfer
Journey information
Overview: Bus from Orlando, FL to Key West, FL
USAUSA
Buses from Orlando, FL to Key West, FL run on average 4 times per day, taking around 9h 36m. Cheap bus tickets for this journey start at €34 if you book in advance.
The earliest bus runs at 00:45, the last at 22:35. The fastest bus covers the 276 miles (445 km) distance in 8h 35m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Plan this route
Journey facts
- Distance276 miles (445 km)
- Average bus duration9h 36m
- Cheapest ticket price€34
- Buses per day4
- Fastest bus8h 35m
- First bus12:45 AM
- Last bus10:35 PM
- Cheapest MonthOct
- Cheapest DayTue
- High SeasonJul - Sep
- Low SeasonJan - Mar
- Best time to book35 days
Understand & plan this route
Explore this journey
Book with confidence
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Frequently asked questions about your Orlando, FL to Key West, FL trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Orlando, FL to Key West, FL.
Cheap bus tickets from Orlando, FL to Key West, FL can start from as little as €34 when you book in advance. The average bus ticket price for Orlando, FL to Key West, FL is €52 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The earliest bus from Orlando, FL to Key West, FL leaves at 12:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Orlando, FL to Key West, FL leaves at 10:35 PM.
There are 4 buses a day from Orlando, FL to Key West, FL which require at least one change with FlixBus, Greyhound. Schedules can vary on holidays or weekends with fewer buses.
Orlando, FL to Key West, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:45AM | Arrival Time 12:30PM | Duration 12h45 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price €44 |
Operator FlixBus | Departure Time 01:15AM | Arrival Time 12:30PM | Duration 12h15 | Departure days Everyday | Cheapest price €44 |
Operator Greyhound | Departure Time 03:35AM | Arrival Time 03:30PM | Duration 11h55 | Departure days Wed, Thu | Cheapest price €43 |
Operator FlixBus | Departure Time 05:20AM | Arrival Time 03:30PM | Duration 10h10 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price €38 |
Operator Greyhound | Departure Time 05:50AM | Arrival Time 03:30PM | Duration 9h40 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price €39 |
Operator Greyhound | Departure Time 11:05PM | Arrival Time 09:30AM | Duration 10h25 | Departure days Mon, Tue, Wed, Thu, Fri, Sun | Cheapest price €38 |
Live departures
Orlando, FL to Key West, FL bus times
The table below shows live departures for Orlando, FL to Key West, FL buses for tomorrow, Sunday, November 1. You can also manually refresh the results below to see updated bus journeys.
Last updated at
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus+ | 12:45 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 12h45 | 12:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL | 1 transfer | |
| FlixBus+ | 1:15 AM Orlando, The Florida Mall, FL | 12h15 | 12:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL | 1 transfer | |
| FlixBus+ | 5:20 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 10h10 | 3:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL | 1 transfer | |
| FlixBus+ | 5:50 AM Orlando, The Florida Mall, FL | 9h40 | 3:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Orlando, FL to Key West, FL buses with Omio?
FlixBus as well as Greyhound offer buses services from Orlando, FL to Key West, FL.
Omio is an official ticket reseller for all your travel options from Orlando, FL to Key West, FL.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Orlando, FL to Key West, FL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Orlando, FL to Key West, FL.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Orlando, FL to Key West, FL.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Orlando, FL to Key West, FL.
Bus companies
Bus companies from Orlando, FL to Key West, FL
Buses from Orlando, FL to Key West, FL with FlixBus and Greyhound. Overnight buses available on this route with FlixBus and Greyhound. Use the details below to compare onboard facilities.
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
9h 10m
Cheapest FlixBus Price
€34
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Greyhound
About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
8h 35m
Cheapest Greyhound Price
€34
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Companies, tickets, and onboard amenities between Orlando, FL and Key West, FL
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
When taking a bus from Orlando, FL to Key West, FL, you can count on FlixBus, Greyhound for the best way to get you to Key West, FL. You can also check all possible bus companies who offer a service between Orlando, FL and Key West, FL and compare the amenities they offer before buying a bus ticket.
Yes, the following accessibility options are available when taking the bus from Orlando, FL to Key West, FL:
- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Orlando, FL to Key West, FL for bus company FlixBus, Greyhound.
Whether you can cancel your bus ticket from Orlando, FL to Key West, FL depends on the bus companies:
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company {providersWithBike}.
Yes, there is food available to purchase on board the bus from Orlando, FL to Key West, FL.
Yes, the following luggage options are included when booking a bus ticket from Orlando, FL to Key West, FL:
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Orlando, FL to Key West, FL:
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Orlando, FL to Key West, FL. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the bus from Orlando, FL to Key West, FL with the following bus company: FlixBus, Greyhound
Yes, there are USB plugs on board the bus from Orlando, FL to Key West, FL with the following bus company: FlixBus, Greyhound.
Yes, there is Wifi on board the bus from Orlando, FL to Key West, FL with the following bus company: FlixBus, Greyhound.
Complete guide to Key West, FL
Things to do in Key West, FL
Discover the best of Key West, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Key West, FL trip today.
- Recommended
Key West Butterfly and Nature Conservatory
The Key West Butterfly and Nature Conservatory features a glass habitat with butterflies, birds, and tropical plants in a calm setting.
- Recommended
Key West Museum of Art and History at the Custom House
The Key West Museum of Art and History at the Custom House presents island history, art, and rotating exhibitions in a grand landmark building.
- Must visit
Duval Street
Duval Street is Key West's main historic thoroughfare, lined with shops, galleries, and lively architecture across the old town.
- Must visit
Mallory Square
Mallory Square is a waterfront plaza known for harbor views, public space, and easy access to the historic seaport district.
- Must visit
Fort Zachary Taylor Historic State Park
Fort Zachary Taylor Historic State Park combines a coastal fort, walking paths, shaded grounds, and one of the island's best natural beaches.
- Vegetarian
Key Lime Pie
Tangy pie made with Key lime juice, sweetened condensed milk, and a graham cracker crust. It is the island's signature dessert and a classic Florida Keys specialty.
- Gluten-free
Key West Pink Shrimp
Fresh local pink shrimp, usually simply peeled and chilled or lightly cooked. They are prized in the Keys for their sweet flavor and local waters.
- Gluten-free
Yellowtail Snapper
Whole snapper, often yellowtail, seasoned and grilled or baked. It reflects Key West's strong fishing culture and the abundance of fresh local catch.
Nine One Five
Polished seafood restaurant focused on Florida fish, oysters, and seasonal ingredients in a refined but approachable dining room.
Sandy's Cafe
Beloved casual spot for Cuban coffee, breakfast, sandwiches, and Cuban toast. A dependable choice for everyday local flavors.
Half Shell Raw Bar
Historic seafood house known for pink shrimp, conch dishes, and classic Key lime pie in a lively, casual Old Town setting.
US Dollar ($)
Very pricey versus many US beach towns; hotels, seafood, and drinks run high, while transit is limited and parking can add costs.
Average meal costs
- Budget
- $12-20 for fast food or casual takeout.
- Mid-range
- $25-45 per person for a restaurant meal.
- Fine dining
- $60+ per person for upscale dining.
- Coffee
- $4-6 for coffee or a latte.
Tipping culture
Tip 18-20% at restaurants, $1-2 per drink at bars, 10-15% for taxis, and small change at cafes.
Plan your visit to Key West, FL
Get destination-focused answers for the end of your trip, including what to do, when to go, practical entry details, and tips for making the most of your time in Key West, FL.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Key West, FL, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Duval Street. Common scams include overpriced taxi rides and timeshare presentations that pressure visitors into purchases. It's advisable to use licensed transportation and be vigilant with personal belongings to stay safe.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.
FAQs: Bus from Orlando, FL to Key West, FL
Find answers to the most common questions about traveling from Orlando, FL to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.
It's helpful to compare your options as there are 2 ways to travel between Orlando, FL and Key West, FL including taking a bus and flight.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
popular bus stations
Popular bus stations from Orlando, FL to Key West, FL
Most Orlando, FL to Key West, FL buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to Key West, South Roosevelt Boulevard (Key West International Airport) station pair. Use this guide to compare Orlando, FL and Key West, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Departure bus stations in Orlando
Arrival bus stations in Key West
Which Orlando, FL station do buses to Key West, FL leave from?
Buses from Orlando, FL to Key West, FL leave from Orlando, N John Young Pkwy (Greyhound Bus Station). The station is 1 miles (3 km) from Orlando, FL city centre at 555 John Young Pkwy, Orlando, FL 32805, USA.
Orlando, N John Young Pkwy (Greyhound Bus Station)555 John Young Pkwy, Orlando, FL 32805, USA
City-centre transport
Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre
Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:
Bus125 · 40m · €2 · every ~6 min
125 · 41m · €2 · every ~6 min
Orlando, N John Young Pkwy (Greyhound Bus Station) bus station facilities and services
Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Tickets and information
Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).
Parking, taxis and toilets
Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.
Orlando, The Florida MallOrlando Florida Mall Ave,Florida Mall Ave 1632,32809
City-centre transport
Getting to Orlando, The Florida Mall from Orlando city centre
Bus42 · 26m · €2 · every ~5 min
Which Key West, FL station do buses from Orlando, FL arrive at?
Buses from Orlando, FL to Key West, FL arrive at Key West, South Roosevelt Boulevard (Key West International Airport). Key West, South Roosevelt Boulevard (Key West International Airport) is 1 miles (3 km) from Key West, FL city centre.
Key West, South Roosevelt Boulevard (Key West International Airport)Key West International Airport, 3491 S Roosevelt Blvd, Key West, FL 33040, USA
City-centre transport
Getting to Key West, South Roosevelt Boulevard (Key West International Airport) from Key West city centre
Key West, South Roosevelt Boulevard (Key West International Airport) is 2 km from Key West city centre. Public transport options include:
TRUE
Key West, South Roosevelt Boulevard (Key West International Airport) bus station facilities and services
Key West, South Roosevelt Boulevard (Key West International Airport) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Key West, South Roosevelt Boulevard (Key West International Airport). ATMs are available at Key West, South Roosevelt Boulevard (Key West International Airport).
Tickets and information
Ticket office support is available at Key West, South Roosevelt Boulevard (Key West International Airport).
Parking, taxis and toilets
Available at Key West, South Roosevelt Boulevard (Key West International Airport): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Key West, South Roosevelt Boulevard (Key West International Airport): The station is wheelchair accessible.
Bus stations for Orlando, FL to Key West, FL
Check bus stations information for Orlando, FL and Key West, FL, including where buses depart and arrive on this route.
When departing from Orlando, FL , you have various bus station options to start your journey from including Orlando, N John Young Pkwy (Greyhound Bus Station), Orlando, The Florida Mall . When arriving in Key West, FL , you can end your journey in bus stations like Key West, South Roosevelt Boulevard (Key West International Airport) .Passengers board the bus most frequently from Orlando, N John Young Pkwy (Greyhound Bus Station), which is located around 1 miles (3 km) away from the city centre, and they get off the bus at Key West, South Roosevelt Boulevard (Key West International Airport), located 3 away from the city centre.
Most popular bus connections from Orlando, FL
Most popular buses to and from Key West, FL and Orlando, FL
Most popular bus connections to Key West, FL
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
