Orlando, FL to Key West, FL bus with FlixBus

Thu, Sep 17
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The cheapest and fastest buses from Orlando, FL to Key West, FL

Showing times, prices and bookable tickets for Sep 17

Cheapest price on Sep 17

$50

Average ticket price on Sep 17

$51

Fastest journey on Sep 17

10 h 25 m

Average journey duration on Sep 17

12 h 12 m

Buses on Sep 17

3

Distance

445 km

Cheap tickets

The best way to find a cheap bus ticket from Orlando, FL to Key West, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Orlando, FL to Key West, FL will cost around $51 if you buy it on the day, but the cheapest tickets can be found for only $50.

Fast buses

It's difficult to get from Orlando, FL to Key West, FL without transferring at least once.

  • Greyhound ·
    11:05 PM10h25
    Orlando, N John Young Pkwy (Greyhound Bus Station)
    9:30 AMKey West, South Roosevelt Boulevard (Key West International Airport), FL
    $501One-way
    1 transfer
  • Greyhound ·
    3:35 AM11h55
    Orlando, N John Young Pkwy (Greyhound Bus Station)
    3:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FL
    $511One-way
    1 transfer
  • FlixBusFlixBus+Greyhound
    1:15 AM14h15
    Orlando, The Florida Mall, FL
    3:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FL
    $521One-way
    1 transfer

Travel Information

Compare bus and flight for Orlando, FL to Key West, FL

Omio recommends booking the bus as it is the most popular option from Orlando, FL to Key West, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of $69 For those with little time, consider booking a flight, which has an average total journey time of 4h 46m. Average ticket prices depend on the travel mode: a bus costs an average of $69, while a flight costs an average of $553.

Distance: 276 miles (445 km)

Compare bus with

Most popular
Bus
Flight
Driving

$69

Average price

Cheapest

$553

Average price

$132

Average price

(fuel + tolls)

10h 5m

Average total duration

9h 35m

Onboard

+

30m

Additional time*

4h 46m

Average total duration

Fastest

2h 46m

Onboard

+

2h 0m

Additional time*

6h 33m

Average total duration

(door-to-door)

FlixBus

Most popular bus company

American Airlines

Most popular airline

Your own car or car rental

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Orlando, FL to Key West, FL is a bus with an average price of $69.

This is compared to other travel options from Orlando, FL to Key West, FL:

A bus is $484 less than a flight for this route with tickets for a flight from Orlando, FL to Key West, FL costing on average $553.

The fastest way to travel from Orlando, FL to Key West, FL is by flight with an average journey time of 2h 46m.

Other travel options to Key West, FL take longer:

Bus takes on average 9h 35m.

It's helpful to compare your options as there are 2 ways to travel between Orlando, FL and Key West, FL including taking a bus and flight.
We recommend using the bus as it is the most popular way to get from Orlando, FL to Key West, FL among Omio's users.
Take the bus. It's the cheapest way to make this trip, and the price gap is usually bigger than people expect.

Tickets start at around $69 compared to roughly $132 in fuel and tolls — a saving of about $63. The journey takes 9h 35m versus 6h 33m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.

Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.

Orlando, FL to Key West, FL Bus Timetables

OperatorDeparture TimeArrival TimeDurationDeparture daysCheapest price
Operator
FlixBus
Departure Time
12:45AM
Arrival Time
12:30PM
Duration
11h45
Departure days
Mon, Tue, Fri, Sat, Sun
Cheapest price
$49
Operator
FlixBus
Departure Time
01:15AM
Arrival Time
03:30PM
Duration
14h15
Departure days
Everyday
Cheapest price
$49
Operator
Greyhound
Departure Time
03:35AM
Arrival Time
03:30PM
Duration
11h55
Departure days
Wed, Thu
Cheapest price
$48
Operator
FlixBus
Departure Time
05:20AM
Arrival Time
03:30PM
Duration
10h10
Departure days
Mon, Tue, Fri, Sat, Sun
Cheapest price
$44
Operator
Greyhound
Departure Time
05:50AM
Arrival Time
03:30PM
Duration
9h40
Departure days
Mon, Tue, Fri, Sat, Sun
Cheapest price
$44
Operator
Greyhound
Departure Time
11:05PM
Arrival Time
09:30AM
Duration
10h25
Departure days
Everyday
Cheapest price
$44

Live departures

Orlando, FL to Key West, FL bus times

The table below shows live departures for Orlando, FL to Key West, FL buses for today, Wednesday, September 16. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
Greyhound · 11:05 PM Orlando, N John Young Pkwy (Greyhound Bus Station)
10h25
9:30 AM Key West, South Roosevelt Boulevard (Key West International Airport), FL1 transfer
Thursday, September 17
FlixBusFlixBus+Greyhound1:15 AM Orlando, The Florida Mall, FL
14h15
3:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL1 transfer
Greyhound · 3:35 AM Orlando, N John Young Pkwy (Greyhound Bus Station)
11h55
3:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL1 transfer

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Orlando, FL to Key West, FL by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Orlando, FL to Key West, FL buses with Omio?

FlixBus as well as Greyhound offer buses services from Orlando, FL to Key West, FL.
Omio is an official ticket reseller for all your travel options from Orlando, FL to Key West, FL.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Orlando, FL to Key West, FL.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Orlando, FL to Key West, FL.

Why book with Omio over Wanderu or Trainline?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Orlando, FL to Key West, FL.
  • Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Orlando, FL to Key West, FL.

Journey information

Overview: Bus from Orlando, FL to Key West, FL

USAUSA
USAUSA
Icon of bus

Buses from Orlando, FL to Key West, FL run on average 4 times per day, taking around 9h 35m. Cheap bus tickets for this journey start at $49 if you book in advance.

The earliest bus runs at 00:45, the last at 22:35. The fastest bus covers the 276 miles (445 km) distance in 8h 35m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
276 miles (445 km)
Average bus duration
9h 35m
Cheapest ticket price
$49
Buses per day
4
Fastest bus
8h 35m
First bus
12:45 AM
Last bus
10:35 PM
Cheapest Month
Oct
Cheapest Day
Wed
High Season
Jul - Sep
Low Season
Jan - Mar
Best time to book
35 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, Greyhound from Orlando, FL to Key West, FLYou can travel by bus between Orlando, FL to Key West, FL with FlixBus, Greyhound for as low as $49. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
9h 10m
Cheapest FlixBus Price
$50
FlixBus frequency
3 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Learn more about FlixBus

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Greyhound Duration
8h 35m
Cheapest Greyhound Price
$49
Greyhound frequency
2 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.
Learn more about Greyhound

FAQs: Bus from Orlando, FL to Key West, FL

Find answers to the most common questions about traveling from Orlando, FL to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Orlando, FL to Key West, FL can start from as little as $49 when you book in advance. The average bus ticket price for Orlando, FL to Key West, FL is $69 ; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by bus from Orlando, FL to Key West, FL is 8h 35m to travel the 276 miles (445 km) long journey. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest bus from Orlando, FL to Key West, FL leaves at 12:45 AM. Plan your trip with the Journey Planner from Omio.
The latest bus from Orlando, FL to Key West, FL leaves at 10:35 PM.
There are 4 buses a day from Orlando, FL to Key West, FL which require at least one change with FlixBus, Greyhound. Schedules can vary on holidays or weekends with fewer buses.
When taking a bus from Orlando, FL to Key West, FL, you can count on FlixBus, Greyhound for the best way to get you to Key West, FL. You can also check all possible bus companies who offer a service between Orlando, FL and Key West, FL and compare the amenities they offer before buying a bus ticket.
When departing from Orlando, FL , you have various bus station options to start your journey from including Orlando, N John Young Pkwy (Greyhound Bus Station), Orlando, The Florida Mall, FL . When arriving in Key West, FL , you can end your journey in bus stations like Key West, South Roosevelt Boulevard (Key West International Airport), FL .Passengers board the bus most frequently from Orlando, N John Young Pkwy (Greyhound Bus Station), which is located around 1 miles (3 km) away from the city centre, and they get off the bus at Key West, South Roosevelt Boulevard (Key West International Airport), FL, located 2 away from the city centre.
A trip to Key West, FL from Orlando, FL is worth doing but not as a day trip with a journey time of 8h 35m each way. Check with Omio app the best way to travel.
The cheapest month for a bus from Orlando, FL to Key West, FL is October.
It's helpful to compare your options as there are 2 ways to travel between Orlando, FL and Key West, FL including taking a bus and flight.
Yes, the following accessibility options are available when taking the bus from Orlando, FL to Key West, FL:
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Orlando, FL to Key West, FL for bus company FlixBus, Greyhound.
Some of the most interesting sights to explore in Key West, FL are:
  • Ernest Hemingway Home and Museum, the former residence of the famous author featuring guided tours and a colony of six-toed cats
  • Key West Butterfly and Nature Conservatory, a lush habitat housing hundreds of butterflies and exotic birds
  • Fort Zachary Taylor Historic State Park, a Civil War-era fort offering beach access, snorkeling, and picnic areas
  • Mallory Square, a waterfront plaza known for its nightly sunset celebrations and street performances
  • Key West Lighthouse and Keeper's Quarters Museum, offering panoramic views of the island and insights into maritime history.
The best things to do in Key West, FL include:
  • Duval Street, stroll along the vibrant street lined with shops, bars, and restaurants
  • Dry Tortugas National Park, visit the remote park known for its historic fort and snorkeling opportunities
  • Southernmost Point Buoy, take a photo at the iconic landmark marking the southernmost point in the continental USA
  • Key West Ghost and Mysteries Tour, embark on a guided tour exploring the haunted history of the island
  • Fury Water Adventures, enjoy a variety of water sports including snorkeling, parasailing, and sunset cruises.
Whether you can cancel your bus ticket from Orlando, FL to Key West, FL depends on the bus companies:
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the bus with bus company FlixBus, Greyhound.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
Yes, there is food available to purchase on board the bus from Orlando, FL to Key West, FL.
Yes, the following luggage options are included when booking a bus ticket from Orlando, FL to Key West, FL:
  • Greyhound
    • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a bus ticket from Orlando, FL to Key West, FL:
  • Greyhound
    • $15 per additional bag.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the bus from Orlando, FL to Key West, FL. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the bus from Orlando, FL to Key West, FL with the following bus company: FlixBus, Greyhound
Yes, there are USB plugs on board the bus from Orlando, FL to Key West, FL with the following bus company: FlixBus, Greyhound.
Yes, there is Wifi on board the bus from Orlando, FL to Key West, FL with the following bus company: FlixBus, Greyhound.
Since neither Orlando, FL nor Key West, FL are in the Schengen Area, passport requirements depend on the specific immigration rules of United States and United States. Entry and visa requirements can be subject to change. For the latest information, check with your destination's embassy or consulate.
We recommend using the bus as it is the most popular way to get from Orlando, FL to Key West, FL among Omio's users.
The currency used in the United States is the US Dollar (USD). For travelers, using cards is generally more convenient and widely accepted, especially credit and debit cards, while cash is useful for small purchases or places that do not accept cards.
In Key West, FL, travelers should be cautious of pickpocketing and petty theft, especially in crowded areas like Duval Street. Common scams include overpriced taxi rides and timeshare presentations that pressure visitors into purchases. It's advisable to use licensed transportation and be vigilant with personal belongings to stay safe.
Pack lightweight, versatile clothing suitable for the destination's climate, and use secure, lockable luggage to protect belongings. Keep essential items like travel documents, medication, and valuables in a carry-on bag for easy access. Use packing organizers or cubes to maximize space and maintain order. Lastly, include a small first aid kit and personal hygiene items for added comfort during travel.

popular bus stations

Popular bus stations from Orlando, FL to Key West, FL

Most Orlando, FL to Key West, FL buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to Key West, South Roosevelt Boulevard (Key West International Airport) station pair. Use this guide to compare Orlando, FL and Key West, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Orlando
Arrival bus stations in Key West

Which Orlando, FL station do buses to Key West, FL leave from?

Buses from Orlando, FL to Key West, FL leave from Orlando, N John Young Pkwy (Greyhound Bus Station). The station is 1 miles (3 km) from Orlando, FL city centre at 555 John Young Pkwy, Orlando, FL 32805, USA.
Orlando, N John Young Pkwy (Greyhound Bus Station)555 John Young Pkwy, Orlando, FL 32805, USAWifiParkingATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre

Orlando, N John Young Pkwy (Greyhound Bus Station) is 3 km from Orlando city centre. Public transport options include:

Bus125 · 40m · $2 · every ~6 min
125 · 41m · $2 · every ~6 min

Orlando, N John Young Pkwy (Greyhound Bus Station) bus station facilities and services

Orlando, N John Young Pkwy (Greyhound Bus Station) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Wi-Fi and ATMs

Wi-Fi is available at Orlando, N John Young Pkwy (Greyhound Bus Station). ATMs are available at Orlando, N John Young Pkwy (Greyhound Bus Station).

Tickets and information

Ticket office support is available at Orlando, N John Young Pkwy (Greyhound Bus Station).

Parking, taxis and toilets

Available at Orlando, N John Young Pkwy (Greyhound Bus Station): Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Orlando, N John Young Pkwy (Greyhound Bus Station): The station is accessible for individuals with disabilities.

Orlando, The Florida MallOrlando Florida Mall Ave,Florida Mall Ave 1632,32809
City-centre transport

Getting to Orlando, The Florida Mall from Orlando city centre

Bus42 · 26m · $2 · every ~5 min

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