The cheapest and fastest buses from Orlando, FL to Key West, FL
Cheapest price
kr326
Average price
kr352
Fastest journey
9 h 40 m
Average duration
10 h 39 m
Buses per day
5
Distance
445 km
The best way to find a cheap bus ticket from Orlando, FL to Key West, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Orlando, FL to Key West, FL will cost around kr352 if you buy it on the day, but the cheapest tickets can be found for only kr326.
It's difficult to get from Orlando, FL to Key West, FL without transferring at least once.
FlixBus+
5:50 AM9h40Orlando, The Florida Mall, FL3:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FLkr3261One-way1 transfer
· 11:05 PM10h25Orlando, N John Young Pkwy (Greyhound Bus Station)9:30 AMKey West, South Roosevelt Boulevard (Key West International Airport), FLkr3341One-way1 transfer
FlixBus+
5:20 AM10h10Orlando, N John Young Pkwy (Greyhound Bus Station)3:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FLkr3341One-way1 transfer
FlixBus+
1:15 AM11h15Orlando, The Florida Mall, FL12:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FLkr3821One-way1 transfer
FlixBus+
12:45 AM11h45Orlando, N John Young Pkwy (Greyhound Bus Station)12:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FLkr3821One-way1 transfer
FlixBus+
5:50 AM9h40Orlando, The Florida Mall, FL3:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FLkr3261One-way1 transfer
FlixBus+
5:20 AM10h10Orlando, N John Young Pkwy (Greyhound Bus Station)3:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FLkr3341One-way1 transfer
· 11:05 PM10h25Orlando, N John Young Pkwy (Greyhound Bus Station)9:30 AMKey West, South Roosevelt Boulevard (Key West International Airport), FLkr3341One-way1 transfer
FlixBus+
1:15 AM11h15Orlando, The Florida Mall, FL12:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FLkr3821One-way1 transfer
FlixBus+
12:45 AM11h45Orlando, N John Young Pkwy (Greyhound Bus Station)12:30 PMKey West, South Roosevelt Boulevard (Key West International Airport), FLkr3821One-way1 transfer
Travel Information
Compare bus and flight for Orlando, FL to Key West, FL
Omio recommends booking the bus as it is the most popular option from Orlando, FL to Key West, FL among Omio's users. If you are prioritising price take the bus with prices starting from kr334. For those with little time consider booking a flight which can get you there in 3h 52m. The ticket price range depends on the travel mode: a bus costs an average of kr334, and a flight costs an average of kr431.
Distance: 276 miles (445 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
kr622 Average price Cheapest | kr1441 Average price | kr849 Average price (fuel + tolls) |
9h 48m Average total duration 9h 18m Onboard + 30m Additional time* | 6h 52m Average total duration Fastest 3h 52m Onboard + 3h 0m Additional time* | 6h 33m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Orlando, FL to Key West, FL:
A bus is kr820 less than a flight for this route with tickets for a flight from Orlando, FL to Key West, FL costing on average kr1441.
Other travel options to Key West, FL take longer:
Bus takes on average 9h 18m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Orlando, FL to Key West, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator FlixBus | Departure Time 12:45AM | Arrival Time 12:30PM | Duration 11h45 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price kr382 |
Operator FlixBus | Departure Time 01:15AM | Arrival Time 12:30PM | Duration 11h15 | Departure days Everyday | Cheapest price kr382 |
Operator Greyhound | Departure Time 03:35AM | Arrival Time 03:30PM | Duration 11h55 | Departure days Wed | Cheapest price kr422 |
Operator FlixBus | Departure Time 04:30AM | Arrival Time 03:30PM | Duration 11h00 | Departure days Thu | Cheapest price kr350 |
Operator FlixBus | Departure Time 05:20AM | Arrival Time 03:30PM | Duration 10h10 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price kr334 |
Operator Greyhound | Departure Time 05:50AM | Arrival Time 03:30PM | Duration 9h40 | Departure days Mon, Tue, Fri, Sat, Sun | Cheapest price kr326 |
Operator Greyhound | Departure Time 11:05PM | Arrival Time 09:30AM | Duration 10h25 | Departure days Everyday | Cheapest price kr334 |
Live departures
Orlando, FL to Key West, FL bus times
The table below shows live departures for Orlando, FL to Key West, FL buses for today, Sunday, August 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
· | 11:05 PM Orlando, N John Young Pkwy (Greyhound Bus Station) | 10h25 | 9:30 AM Key West, South Roosevelt Boulevard (Key West International Airport), FL | 1 transfer | |
| Monday, August 3 | |||||
FlixBus+![]() | 12:45 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 11h45 | 12:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL | 1 transfer | |
FlixBus+![]() | 1:15 AM Orlando, The Florida Mall, FL | 11h15 | 12:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL | 1 transfer | |
FlixBus+![]() | 5:20 AM Orlando, N John Young Pkwy (Greyhound Bus Station) | 10h10 | 3:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL | 1 transfer | |
FlixBus+![]() | 5:50 AM Orlando, The Florida Mall, FL | 9h40 | 3:30 PM Key West, South Roosevelt Boulevard (Key West International Airport), FL | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Orlando, FL to Key West, FL by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Aug 03
Aug 04
Aug 05
Aug 06
Aug 07
Aug 08
Aug 09
Aug 10
Aug 11
Aug 12
Aug 13
Aug 14
Aug 15
Aug 16
Why should you book Orlando, FL to Key West, FL buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Greyhound to find the best option for your trip from Orlando, FL to Key West, FL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Orlando, FL to Key West, FL.
Why book with Omio over Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Greyhound to find the best option for your trip from Orlando, FL to Key West, FL.
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Orlando, FL to Key West, FL.
Journey information
Overview: Bus from Orlando, FL to Key West, FL
Buses from Orlando, FL to Key West, FL run on average 4 times per day, taking around 9h 18m. Cheap bus tickets for this journey start at kr334 if you book in advance.
The earliest bus runs at 00:45, the last at 22:35. The fastest bus covers the 276 miles (445 km) distance in 9h 25m.
Distance 276 miles (445 km) |
Average bus duration 9h 18m |
Cheapest ticket price kr334 |
Buses per day 4 |
Fastest bus 9h 25m |
First bus 12:45 AM |
Last bus 10:35 PM |
Cheapest Month Oct |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Apr - Jun |
Best time to book 6 days |
Bus providers: FlixBus, Greyhound from Orlando, FL to Key West, FLYou can travel by bus between Orlando, FL to Key West, FL with FlixBus, Greyhound for as low as kr334. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Greyhound
FAQs: Bus from Orlando, FL to Key West, FL
Find answers to the most common questions about traveling from Orlando, FL to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Ernest Hemingway Home and Museum, the former residence of the famous author featuring guided tours and a colony of six-toed cats
- Key West Butterfly and Nature Conservatory, a lush habitat housing hundreds of butterflies and exotic birds
- Fort Zachary Taylor Historic State Park, a Civil War-era fort offering beach access, snorkeling, and picnic areas
- Mallory Square, a waterfront plaza known for its nightly sunset celebrations and street performances
- Key West Lighthouse and Keeper's Quarters Museum, offering panoramic views of the island and insights into maritime history.
- Duval Street, stroll along the vibrant street lined with shops, bars, and restaurants
- Dry Tortugas National Park, visit the remote park known for its historic fort and snorkeling opportunities
- Southernmost Point Buoy, take a photo at the iconic landmark marking the southernmost point in the continental USA
- Key West Ghost and Mysteries Tour, embark on a guided tour exploring the haunted history of the island
- Fury Water Adventures, enjoy a variety of water sports including snorkeling, parasailing, and sunset cruises.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Greyhound
- $15 per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Orlando, FL to Key West, FL
Most Orlando, FL to Key West, FL buses use the Orlando, N John Young Pkwy (Greyhound Bus Station) to Key West, South Roosevelt Boulevard (Key West International Airport) station pair. Use this guide to compare Orlando, FL and Key West, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to Orlando, N John Young Pkwy (Greyhound Bus Station) from Orlando city centre
Getting to Orlando, The Florida Mall from Orlando city centre
Most popular bus connections from Orlando, FL
More options for your journey from Orlando, FL to Key West, FL
Here are some other resources that might have the information you need
