Orlando, FL to Key West, FL bus with FlixBus

Tue, Dec 16
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FlixBus
Greyhound
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
FlixBus
Greyhound
Alsa
BlaBlaCar Bus
Rede Expressos
1,000+ travel companies
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Travel Information

Compare bus and flight for Orlando, FL to Key West, FL

Omio recommends booking the bus as it is the most popular option from Orlando, FL to Key West, FL among Omio's users. If you are prioritising price take the bus with prices starting from €39. For those with little time consider booking a flight which can get you there in 1h 55m. The ticket price range depends on the travel mode: a bus costs an average of €39, and a flight costs an average of €34.

Distance: 276 miles (445 km)

Compare bus with

Most popular
Bus
Flight

€52

Average price

Cheapest

€122

Average price

9h 48m

Average total duration

9h 18m

Onboard

+

30m

Additional time*

4h 55m

Average total duration

Fastest

1h 55m

Onboard

+

3h 0m

Additional time*

Direct Options

Direct Options

Compare prices and tickets Orlando, FL to Key West, FL by bus or flight

Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
Dec 16
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Dec 19
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Journey information

Overview: Bus from Orlando, FL to Key West, FL

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Icon of bus

Buses from Orlando, FL to Key West, FL run on average 5 times per day, taking around 9h 18m. Cheap bus tickets for this journey start at $49 (€39) but you can travel from only $43 (€34) by flight.

The earliest bus runs at 00:45, the last at 22:35. The fastest bus covers the 276 miles (445 km) distance in 9h 25m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $43 (€34)
Distance
276 miles (445 km)
Average bus duration
9h 18m
Cheapest ticket price
$49 (€39)
Buses per day
5
Fastest bus
9h 25m
First bus
00:45
Last bus
22:35
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from $43 (€34)

Bus providers: FlixBus, Greyhound from Orlando, FL to Key West, FLYou can travel by bus between Orlando, FL to Key West, FL with FlixBus, Greyhound for as low as $43 (€34). When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
10h 0m
Cheapest Price
$53 (€42)
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Greyhound

About
Greyhound Lines, Inc. is a prominent American intercity bus transportation provider, established in 1914. It operates the largest intercity bus network in the United States, also extending services to Canada and Mexico. Greyhound is known for offering affordable and reliable long-distance travel, connecting major cities and rural communities across North America. The company's buses are equipped with amenities such as free Wi-Fi, power outlets, and extra legroom to enhance passenger comfort. Greyhound is a subsidiary of Flix SE, which also owns FlixBus, and together they offer an extensive network of over 1,600 destinations.
Luggage & cancellation policy
Average Duration
9h 25m
Cheapest Price
$55 (€44)
Greyhound frequency
3 a day
Luggage included
One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
Additional luggage
$15 per additional bag.
Cancellation Policy
You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Wheelchair-accessible buses.
Bikes
Bikes are allowed.

FAQs: Bus from Orlando, FL to Key West, FL

Find answers to the most common questions about traveling from Orlando, FL to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.

FAQs
Cheap bus tickets from Orlando, FL to Key West, FL can start from as little as $56 (€45) when you book in advance. The average bus ticket price for Orlando, FL to Key West, FL is $63 (€51); however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
On average the Orlando, FL to Key West, FL bus time is 10 h 45 min   covering the 275 mile (444 km) long route, but the journey time can vary depending on specific dates or if traveling on weekends and holidays.
The first bus from Orlando, FL to Key West, FL leaves at 12: 45AM. Plan your trip with the Journey Planner   from Omio.
The last bus from Orlando, FL to Key West, FL leaves at 10: 35PM.
There are 6 buses a day from Orlando, FL to Key West, FL which require at least one change with FlixBus or Greyhound. Schedules can vary on holidays or weekends with fewer buses.
For the route from Orlando, FL to Key West, FL you can take a bus with FlixBus or Greyhound. Be sure to check out all possible bus companies that offer services between Orlando, FL and Key West, FL on Omio to compare what amenities they may have.
The cheapest month for a bus from Orlando, FL to Key West, FL is November.
You have options as you can travel to Key West, FL from Orlando, FL 2 different ways: bus or flight.
Yes, the following accessibility options are available when taking the bus from Orlando, FL to Key West, FL:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Greyhound
    • Assistance
    • Priority seating
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the bus from Orlando, FL to Key West, FL for bus providers FlixBus and Greyhound.
Some of the most interesting sights to explore in Key West, FL are:
  • Ernest Hemingway Home and Museum, the former residence of the famous author featuring guided tours and a colony of six-toed cats
  • Key West Butterfly and Nature Conservatory, a lush habitat housing hundreds of butterflies and exotic birds
  • Fort Zachary Taylor Historic State Park, a Civil War-era fort offering beach access, snorkeling, and picnic areas
  • Mallory Square, a waterfront plaza known for its nightly sunset celebrations and street performances
  • Key West Lighthouse and Keeper's Quarters Museum, offering panoramic views of the island and insights into maritime history.
The best things to do in Key West, FL include:
  • Duval Street, stroll along the vibrant street lined with shops, bars, and restaurants
  • Dry Tortugas National Park, visit the remote park known for its historic fort and snorkeling opportunities
  • Southernmost Point Buoy, take a photo at the iconic landmark marking the southernmost point in the continental USA
  • Key West Ghost and Mysteries Tour, embark on a guided tour exploring the haunted history of the island
  • Fury Water Adventures, enjoy a variety of water sports including snorkeling, parasailing, and sunset cruises.
Yes, bikes are allowed on board the bus with bus providers FlixBus and Greyhound.
Whether you can cancel your bus ticket from Orlando, FL to Key West, FL depends on the bus providers:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Greyhound
    • You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.

To find the cheapest bus tickets for your trip from Orlando, FL to Key West, FL, follow these tips:

  • Book in advance: Tickets are often cheaper when booked early.
  • Be flexible with dates and times: Traveling during off-peak hours or on weekdays can help you save money.
  • Use our search filters: Sort results by price to quickly identify the most affordable options.
  • Look for special deals or discounts: Check for promotions or discounts available on our website and app.
  • Start your search now and compare ticket prices to find the best deal!

    Yes, there is food available to purchase on board the bus from Orlando, FL to Key West, FL.
    Yes, the following luggage options are included when booking a bus ticket from Orlando, FL to Key West, FL:
    • FlixBus
      • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
    • Greyhound
      • One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
    Yes, the following additional luggage options are available when booking a bus ticket from Orlando, FL to Key West, FL:
    • FlixBus
      • Additional luggage can be purchased for a fee.
    • Greyhound
      • $15 per additional bag.
    Yes, you can bring your pet on the bus from Orlando, FL to Key West, FL. The following conditions apply:
    • FlixBus
      • Small pets in carriers allowed
      • Guide dogs travel for free.
    You can reserve your seat on the bus from Orlando, FL to Key West, FL with the following bus providers: FlixBus and Greyhound
    Yes, there are USB plugs on board the bus from Orlando, FL to Key West, FL with the following bus companies: FlixBus and Greyhound.
    Yes, there is Wifi on board the bus from Orlando, FL to Key West, FL with the following bus providers: FlixBus and Greyhound.

    popular bus stations

    Popular bus stations from Orlando, FL to Key West, FL

    Orlando
    Key West
    The major bus station for departures in Orlando is Orlando, N John Young Pkwy (Greyhound Bus Station). Find all the information you need to know about services, amenities and connections at Orlando, N John Young Pkwy (Greyhound Bus Station) for your trip from Orlando to Key West.
    Orlando, N John Young Pkwy (Greyhound Bus Station)
    information
    Orlando, The Florida Mall

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