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Journey information
Overview: Bus from Naples, FL to Key West, FL
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 109 miles (176 km) |
First bus 09:30 |
Last bus 12:55 |
Key Takeaways
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
FAQs: Bus from Naples, FL to Key West, FL
Find answers to the most common questions about traveling from Naples, FL to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.

The first bus from Naples, FL to Key West, FL leaves at 9: 30AM. Plan your trip with the Journey Planner from Omio.
The last bus from Naples, FL to Key West, FL leaves at 12: 55PM.
A day trip to Key West, FL from Naples, FL is worth doing with a journey time of min each way. Check with Omio app the best way to travel.
No, the bus from Naples, FL to Key West, FL has no accessibility options.
No, there are no bathrooms on board the bus from Naples, FL to Key West, FL.
Some of the most interesting sights to explore in Key West, FL are:
- Ernest Hemingway Home and Museum, the former residence of the famous author featuring guided tours and a colony of six-toed cats
- Key West Butterfly and Nature Conservatory, a lush habitat housing hundreds of butterflies and exotic birds
- Fort Zachary Taylor Historic State Park, a Civil War-era fort offering beach access, snorkeling, and picnic areas
- Mallory Square, a waterfront plaza known for its nightly sunset celebrations and street performances
- Key West Lighthouse and Keeper's Quarters Museum, offering panoramic views of the island and insights into maritime history.
The best things to do in Key West, FL include:
- Duval Street, stroll along the vibrant street lined with shops, bars, and restaurants
- Dry Tortugas National Park, visit the remote park known for its historic fort and snorkeling opportunities
- Southernmost Point Buoy, take a photo at the iconic landmark marking the southernmost point in the continental USA
- Key West Ghost and Mysteries Tour, embark on a guided tour exploring the haunted history of the island
- Fury Water Adventures, enjoy a variety of water sports including snorkeling, parasailing, and sunset cruises.
No, bikes are not allowed on board the bus from Naples, FL to Key West, FL.
To find the cheapest bus tickets for your trip from Naples, FL to Key West, FL, follow these tips:
Start your search now and compare ticket prices to find the best deal!
Yes, there is food available to purchase on board the bus from Naples, FL to Key West, FL.
No, luggage for the bus from Naples, FL to Key West, FL needs to be booked in addition.
No, there are no additional luggage options for the bus from Naples, FL to Key West, FL.
Unfortunately, pets are not allowed on the bus from Naples, FL to Key West, FL.
No, there are no USB plugs on board the bus from Naples, FL to Key West, FL.
No, there is no WiFi on board the bus from Naples, FL to Key West, FL.
Most popular bus connections from Naples, FL
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