Travel Information
Compare bus and flight for Los Angeles, CA to Key West, FL
Omio recommends booking the flight as it is the most popular option from Los Angeles, CA to Key West, FL among Omio's users. If you are prioritising price take the bus with prices starting from €485. For those with little time consider booking a flight which can get you there in 9h 21m. The ticket price range depends on the travel mode: a bus costs an average of €485, and a flight costs an average of €565.
Distance: 2279 miles (3668 km)
Compare bus with
| Bus | Most popular Flight |
|---|---|
€485 Average price Cheapest | €565 Average price |
79h 30m Average total duration 79h 0m Onboard + 30m Additional time* | 12h 21m Average total duration Fastest 9h 21m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options |
Compare prices and tickets Los Angeles, CA to Key West, FL by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Los Angeles, CA to Key West, FL buses with Omio?
Why book with Omio vs Greyhound?
- Compare with other providers: On Omio, you can not only buy tickets for Greyhound, but also compare tickets for the likes of to find the best option for your trip from Los Angeles, CA to Key West, FL.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Greyhound with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Los Angeles, CA to Key West, FL.
Why book with Omio over Wanderu?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Los Angeles, CA to Key West, FL.
Journey information
Overview: Bus from Los Angeles, CA to Key West, FL
Buses from Los Angeles, CA to Key West, FL run on average 3 times per day, taking around 79h 0m. Cheap bus tickets for this journey start at $613 (€485) if you book in advance.
The earliest bus runs at 09:35, the last at 23:30. The fastest bus covers the 2279 miles (3668 km) distance in 79h 0m.
Distance 2279 miles (3668 km) |
Average bus duration 79h 0m |
Cheapest ticket price $613 (€485) |
Buses per day 3 |
Fastest bus 79h 0m |
First bus 09:35 |
Last bus 23:30 |
Bus providers: Greyhound from Los Angeles, CA to Key West, FLYou can travel by bus between Los Angeles, CA to Key West, FL with Greyhound for as low as $613 (€485). When you search for schedules and tickets, Omio will show you the best journey
Greyhound
FAQs: Bus from Los Angeles, CA to Key West, FL
Find answers to the most common questions about traveling from Los Angeles, CA to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.

- Greyhound
- Assistance
- Priority seating
- Wheelchair-accessible buses.
- Ernest Hemingway Home and Museum, the former residence of the famous author featuring guided tours and a colony of six-toed cats
- Key West Butterfly and Nature Conservatory, a lush habitat housing hundreds of butterflies and exotic birds
- Fort Zachary Taylor Historic State Park, a Civil War-era fort offering beach access, snorkeling, and picnic areas
- Mallory Square, a waterfront plaza known for its nightly sunset celebrations and street performances
- Key West Lighthouse and Keeper's Quarters Museum, offering panoramic views of the island and insights into maritime history.
- Duval Street, stroll along the vibrant street lined with shops, bars, and restaurants
- Dry Tortugas National Park, visit the remote park known for its historic fort and snorkeling opportunities
- Southernmost Point Buoy, take a photo at the iconic landmark marking the southernmost point in the continental USA
- Key West Ghost and Mysteries Tour, embark on a guided tour exploring the haunted history of the island
- Fury Water Adventures, enjoy a variety of water sports including snorkeling, parasailing, and sunset cruises.
- Greyhound
- You can cancel your ticket for a refund or exchange up to 24 hours before departure, for a cancellation fee applied.
- Greyhound
- One carry-on bag up to 25 lbs (11 kg) and one checked bag up to 50 lbs (23 kg).
- Greyhound
- $15 per additional bag.
popular bus stations
Popular bus stations from Los Angeles, CA to Key West, FL
Most popular bus connections from Los Angeles, CA
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