Travel Information
Compare bus and flight for Los Angeles, CA to Key West, FL
Omio recommends booking the bus as it is the most popular option from Los Angeles, CA to Key West, FL among Omio's users. If you are prioritising price take the bus with prices starting from $279. For those with little time consider booking a flight which can get you there in 7h 40m. The ticket price range depends on the travel mode: a bus costs an average of $279, and a flight costs an average of $478.
Distance: 2279 miles (3668 km)
Compare bus with
Most popular Bus | Flight | Driving |
|---|---|---|
$283 Average price Cheapest | $489 Average price | $578 Average price (fuel + tolls) |
77h 28m Average total duration 76h 58m Onboard + 30m Additional time* | 10h 40m Average total duration Fastest 7h 40m Onboard + 3h 0m Additional time* | 42h 7m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Los Angeles, CA to Key West, FL:
A bus is $207 (€167) less than a flight for this route with tickets for a flight from Los Angeles, CA to Key West, FL costing on average $489 (€396).
Other travel options to Key West, FL take longer:
Bus takes on average 76h 58m.
You'll arrive about {timeSavings} sooner ({durationInMinutes} by bus vs {drivingDurationInMinutes} by car) and save roughly {savingsAmount} compared to fuel and tolls ({cheapestPrice} vs {drivingPriceInCents}). You also skip the drive itself — no traffic stress, no parking, and you can use the time to work, nap, or catch up on a series with the onboard Wi-Fi.
Direct coaches are operated by {directProviders}.
Driving is still worth considering if you're travelling with bulky luggage, need flexibility on departure times, or plan to stop along the way.
Los Angeles, CA to Key West, FL Bus Timetables
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 06:30AM | Arrival Time 01:30PM | Duration 79h00 | Departure days Sun | Cheapest price $279 |
Operator Greyhound | Departure Time 04:35PM | Arrival Time 07:30PM | Duration 74h55 | Departure days Sat | Cheapest price $287 |
Compare prices and tickets Los Angeles, CA to Key West, FL by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Los Angeles, CA to Key West, FL
Buses from Los Angeles, CA to Key West, FL run on average 3 times per day, taking around 76h 58m. Cheap bus tickets for this journey start at $279 (€225) if you book in advance.
The earliest bus runs at 09:35, the last at 23:30. The fastest bus covers the 2279 miles (3668 km) distance in 74h 55m.
Distance 2279 miles (3668 km) |
Average bus duration 76h 58m |
Cheapest ticket price $279 (€225) |
Buses per day 3 |
Fastest bus 74h 55m |
First bus 9:35 AM |
Last bus 11:30 PM |
Cheapest Month Apr |
Cheapest Day Sat |
High Season Jan - Mar |
Low Season Jul - Sep |
FAQs: Bus from Los Angeles, CA to Key West, FL
Find answers to the most common questions about traveling from Los Angeles, CA to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.

- Ernest Hemingway Home and Museum, the former residence of the famous author featuring guided tours and a colony of six-toed cats
- Key West Butterfly and Nature Conservatory, a lush habitat housing hundreds of butterflies and exotic birds
- Fort Zachary Taylor Historic State Park, a Civil War-era fort offering beach access, snorkeling, and picnic areas
- Mallory Square, a waterfront plaza known for its nightly sunset celebrations and street performances
- Key West Lighthouse and Keeper's Quarters Museum, offering panoramic views of the island and insights into maritime history.
- Duval Street, stroll along the vibrant street lined with shops, bars, and restaurants
- Dry Tortugas National Park, visit the remote park known for its historic fort and snorkeling opportunities
- Southernmost Point Buoy, take a photo at the iconic landmark marking the southernmost point in the continental USA
- Key West Ghost and Mysteries Tour, embark on a guided tour exploring the haunted history of the island
- Fury Water Adventures, enjoy a variety of water sports including snorkeling, parasailing, and sunset cruises.
popular bus stations
Popular bus stations from Los Angeles, CA to Key West, FL
Most popular bus connections from Los Angeles, CA
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