- Must visit
Ernest Hemingway Home and Museum
The Ernest Hemingway Home and Museum lets visitors tour the writer's residence, gardens, and rooms tied to his Key West years.
Cheapest price on Sep 20
€187
Average ticket price on Sep 20
€189
Fastest journey on Sep 20
1 d 17 h
Average journey duration on Sep 20
1 d 17 h 38 m
Buses on Sep 20
2
Distance
1980 km
The best way to find a cheap bus ticket from Detroit, MI to Key West, FL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Detroit, MI to Key West, FL will cost around €189 if you buy it on the day, but the cheapest tickets can be found for only €187.
On Sun, Sep 20, we found 2 buses from Detroit, MI to Key West, FL, including 2 direct services.
On Sun, Sep 20 the direct buses cover the 1980 km distance in an average of 1 d 17 h 38 m but if you time it right, some buses will get you there in just 1 d 17 h .
On Sun, Sep 20 the slowest buses will take 1 d 18 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Omio recommends booking the bus as it is the most popular option from Detroit, MI to Key West, FL among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €193 For those with little time, consider booking a bus, which has an average total journey time of 36h 10m. Average ticket prices depend on the travel mode: a bus costs an average of €193, while a bus costs an average of €193.
Distance: 1230 miles (1980 km)
Most popular Bus | Driving |
|---|---|
€193 Average price Cheapest | €250 Average price (fuel + tolls) |
36h 10m Average total duration Fastest 35h 40m Onboard + 30m Additional time* | 23h 9m Average total duration (door-to-door) |
![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options |
Tickets start at around €193 compared to roughly €250 in fuel and tolls — a saving of about €57. The journey takes 35h 40m versus 23h 9m by car, so you'll arrive a bit later, but you can use the time productively rather than spending it behind the wheel. No parking to sort, no fuel stops, and most coaches have Wi-Fi and power outlets.
Driving is worth considering if you're on a tight schedule, travelling as a group (where fuel costs split several ways), or want the flexibility to stop along the way.
| Operator | Departure Time | Arrival Time | Duration | Departure days | Cheapest price |
|---|---|---|---|---|---|
Operator Greyhound | Departure Time 12:15AM | Arrival Time 07:30PM | Duration 43h15 | Departure days Fri | Cheapest price €222 |
Operator Greyhound | Departure Time 12:30AM | Arrival Time 05:30PM | Duration 41h00 | Departure days Sun | Cheapest price €187 |
Operator Greyhound | Departure Time 01:15AM | Arrival Time 07:30PM | Duration 42h15 | Departure days Sun | Cheapest price €191 |
Operator Greyhound USA | Departure Time 07:15AM | Arrival Time 01:02PM | Duration 53h47 | Departure days Wed, Fri | Cheapest price €333 |
The table below shows live departures for Detroit, MI to Key West, FL buses for tomorrow, Saturday, September 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 12:30 AM Detroit, MI | 41h00 | 5:30 PM Key West, FL | 0 transfersDirect | |
![]() | 1:15 AM Detroit, MI | 42h15 | 7:30 PM Key West, FL | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Buses from Detroit, MI to Key West, FL run on average 2 times per day, taking around 35h 40m. Cheap bus tickets for this journey start at €187 if you book in advance.
The earliest bus runs at 07:15, the last at 07:15. The fastest bus covers the 1230 miles (1980 km) distance in 35h 34m.
Distance 1230 miles (1980 km) |
Average bus duration 35h 40m |
Cheapest ticket price €187 |
Buses per day 2 |
Fastest bus 35h 34m |
First bus 7:15 AM |
Last bus 7:15 AM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Oct - Dec |
Best time to book 70 days |
Discover the best of Key West, FL — top attractions, local food, transport tips, budget advice, and currency essentials. Plan your perfect Key West, FL trip today.
The Ernest Hemingway Home and Museum lets visitors tour the writer's residence, gardens, and rooms tied to his Key West years.
The Key West Butterfly and Nature Conservatory features a glass habitat with butterflies, birds, and tropical plants in a calm setting.
The Key West Museum of Art and History at the Custom House presents island history, art, and rotating exhibitions in a grand landmark building.
Duval Street is Key West's main historic thoroughfare, lined with shops, galleries, and lively architecture across the old town.
Mallory Square is a waterfront plaza known for harbor views, public space, and easy access to the historic seaport district.
Fort Zachary Taylor Historic State Park combines a coastal fort, walking paths, shaded grounds, and one of the island's best natural beaches.
Find answers to the most common questions about traveling from Detroit, MI to Key West, FL by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Key West, FL, this guide helps you travel smarter and with confidence.

Most Detroit, MI to Key West, FL buses use the Detroit, Greyhound Terminal to Key West, South Roosevelt Boulevard (Key West International Airport) station pair. Use this guide to compare Detroit, MI and Key West, FL bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Detroit, Greyhound Terminal is 1 km from Detroit city centre. Public transport options include:
Detroit, Greyhound Terminal has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food options include: Fast food and coffee shops available.
Free Wi-Fi available in waiting areas. ATMs are aTM located near the main entrance.
Ticket office support is available at Detroit, Greyhound Terminal.
Available at Detroit, Greyhound Terminal: Parking, Taxis, WC.
Accessibility facilities are available at Detroit, Greyhound Terminal: Wheelchair accessible facilities available.
Key West, South Roosevelt Boulevard (Key West International Airport) is 2 km from Key West city centre. Public transport options include:
Key West, South Roosevelt Boulevard (Key West International Airport) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi is available at Key West, South Roosevelt Boulevard (Key West International Airport). ATMs are available at Key West, South Roosevelt Boulevard (Key West International Airport).
Ticket office support is available at Key West, South Roosevelt Boulevard (Key West International Airport).
Available at Key West, South Roosevelt Boulevard (Key West International Airport): Parking, Taxis, WC.
Accessibility facilities are available at Key West, South Roosevelt Boulevard (Key West International Airport): The station is wheelchair accessible.
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